Systemic control of plasmacytoid dendritic cells by CD8+ T cells and commensal microbiota

Journal of Immunology

Volumn 180, Issue 9, 2008, Pages 5843-5852

  Fujiwara, Daisuke ^a   Wei, Bo ^a   Presley, Laura L ^b   Brewer, Sarah ^a   McPherson, Michael ^a   Lewinski, Michael A ^a   Borneman, James ^b   Braun, Jonathan ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD8BETA ANTIBODY; LYMPHOCYTE ANTIBODY; PERFORIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CD8+ T LYMPHOCYTE; CELL FUNCTION; COLITIS; COMMENSAL; CONTROLLED STUDY; DENDRITIC CELL; DISEASE PREDISPOSITION; GENOTYPE; GERMFREE ANIMAL; IMMUNE RESPONSE; IMMUNOREGULATION; INTESTINE FLORA; MOUSE; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BACTERIUM; GENETICS; IMMUNOLOGY; INTESTINE; MICROBIOLOGY; MOUSE MUTANT; PLASMA CELL; TRANSPLANTATION;

ANIMALS; BACTERIA; CD8-POSITIVE T-LYMPHOCYTES; COLITIS; DENDRITIC CELLS; INTESTINES; MICE; MICE, KNOCKOUT; PERFORIN; PLASMA CELLS; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 44449093654     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.180.9.5843     Document Type: Article

References (54)

1. Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392: 245-252. (Pubitemid 28155090)
2. Villadangos, J. A., and P. Schnorrer. 2007. Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets in vivo. Nat. Rev. Immunol. 7: 543-555.2.
3. Shortman, K., and Y. J. Liu. 2002. Mouse and human dendritic cell subtypes. Nat. Rev. Immunol. 2: 151-161. (Pubitemid 37336516)
4. Asselin-Paturel, C., G. Brizard, J. J. Pin, F. Briere, and G. Trinchieri. 2003. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody. J. Immunol. 171: 6466-6477. (Pubitemid 37532075)
5. Fallarino, F., C. Orabona, C. Vacca, R. Bianchi, S. Gizzi, C. Asselin-Paturel, M. C. Fioretti, G. Trinchieri, U. Grohmann, and P. Puccetti. 2005. Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells. Int. Immunol. 17: 1429-1438. (Pubitemid 41631319)
6. Liu, Y. J. 2001. Dendritic cell subsets and lineages, and their functions in innate and adaptive immunity. Cell 106: 259-262. (Pubitemid 32772608)
7. Colonna, M., G. Trinchieri, and Y. J. Liu. 2004. Plasmacytoid dendritic cells in immunity. Nat. Immunol. 5: 1219-1226. (Pubitemid 41057736)
8. + regulatory T cells. J. Immunol. 173: 4433-4442.
9. Mellor, A. L., B. Baban, P. Chandler, B. Marshall, K. Jhaver, A. Hansen, P. A. Koni, M. Iwashima, and D. H. Munn. 2003. Induced indoleamine 2,3 dioxygenase expression in dendritic cell subsets suppresses T cell clonal expansion. J. Immunol. 171: 1652-1655. (Pubitemid 36966447)
10. Fallarino, F., C. Asselin-Paturel, C. Vacca, R. Bianchi, S. Gizzi, M. C. Fioretti, G. Trinchieri, U. Grohmann, and P. Pucceti. 2004. Murine plasmacytoid dendritic cells initiate the immunosuppressive pathway of tryptophan catabolism in response to CD200 receptor engagement. J. Immunol. 173: 3748-3754. (Pubitemid 39280736)
11. Agrawal, S., A. Agrawal, B. Doughty, A. Gerwitz, J. Blenis, T. Van Dyke, and B. Pulendran. 2003. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th response via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J. Immunol. 171: 4984-4989. (Pubitemid 37432777)
12. Sparwasser, T., E. S. Koch, R. M. Vabulas, K. Heeg, G. B. Lipford, J. W. Ellwart, and H. Wagner. 1998. Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells. Eur. J. Immunol. 28: 2045-2054. (Pubitemid 28271721)
13. Edwards, A. D., S. P. Manickasingham, R. Sporri, S. S. Diebold, O. Schulz, A. Sher, T. Kaisho, S. Akira, and C. Reis e Sousa. 2002. Microbial recognition via Toll-like receptor-dependent response of murine dendritic cells subsets to CD40 triggering. J. Immunol. 169: 3652-3660.
14. Walton, K. L. W., J. He, B. L. Kelsall, R. B. Sartor, and N. C. Fisher. 2006. Dendritic cells in germ-free and specific pathogen-free mice have similar phenotypes and in vitro antigen presenting function. Immunol. Lett. 102: 16-24. (Pubitemid 41606035)
15. Savage, D. C. 1977. Microbial ecology of the gastrointestinal tract. Annu. Rev. Microbiol. 31: 107-133.
16. Conway, P.-L. 1995. Microbial ecology of the human large intestine. In Human Colonic Bacteria: Role in Nutrition, Physiology and Pathology. G. R. Gibson and G. T. Macfarlane, eds. Boca Raton, FL, CRC, pp. 1-24.
17. Mackie, R. I., A. Sghir, and H. R. Gaskins. 1999. Developmental microbial ecology of the neonatal gastrointestinal tract. Am. J. Clin. Nutr. 69: 1035S-1045S.
18. Camerini, V., B. C. Sydora, R. Aranda, C. Nguyen, C. MacLean, W. H. McBride, and M. Kronenberg. 1998. Generation of intestinal mucosal lymphocytes in SCID mice reconstituted with mature, thymus-derived T cells. J. Immunol. 160: 2608-2618. (Pubitemid 28136710)
19. Scupham, A. J., L. L. Presley, B. Wei, E. Bent, N. Griffith, M. McPherson, F. Zhu, O. Oluwadara, N. Rao, J. Braun, and J. Borneman. 2006. Abundant and diverse fungal microbiota in the murine intestine. Appl. Environ. Microbiol. 72: 793-801.
20. Eckburg, P. B., E. M. Bik, C. N. Bernstein, E. Purdom, L. Dethlefsen, M. Sargent, S. R. Gill, K. E. Nelson, and D. A. Relman. 2005. Diversity of the human intestinal microbial flora. Science 308: 1635-1638.
21. Ley, R. E., P. J. Turnbaugh, S. Klein, and J. I. Gordon. 2006. Microbial ecology: human gut microbes associated with obesity. Nature 444: 1022-1023. (Pubitemid 46018512)
22. + T lymphocytes. Clin. Immunol. 117: 221-230.
23. high T cells to SCID recipients. J. Immunol. 158: 3464-3473.
24. + T cells in Tap-1 mutant mice. Proc. Natl. Acad. Sci. USA 91: 6525-6528.
25. van den Broek, M. E., D. Kagi, F. Ossendorp, R. Toes, S. Vamvakas, W. K. Lutz, C. J. Melief, R. M. Zinkernagel, and H. Hengartner. 1996. Decreased tumor surveillance in perforin-deficient mice. J. Exp. Med. 184: 1781-1790. (Pubitemid 26404469)
26. Nagai, Y., K. P. Garrett, S. Ohta, U. Bahrun, T. Kouro, S. Akira, K. Takatsu, and P. W. Kincade. 2006. Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment. Immunity 24: 801-812. (Pubitemid 43867369)
27. Tacke, F., F. Ginhoux, C. Jakubzick, N. V. Rooijen, M. Merad, and G. J. Randolph. 2006. Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery. J. Exp. Med. 203: 583-597.
28. Gilliet, M., and Y. J. Liu. 2002. Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells. J. Exp. Med. 195: 695-704. (Pubitemid 34259715)
29. + dendritic cells only after microbial stimulus. J. Exp. Med. 198: 1307-1319.
30. + NKT cells. Eur. J. Immunol. 30: 2300-2311.
31. Allman, D., M. Dalod, C. Asselin-Paturel, T. Delale, S. H. Robbins, G. Trinchieri, C. A. Biron, P. Kastner, and S. Chan. 2006. Ikaros is required for plasmacytoid dendritic cell differentiation. Blood 108: 4025-4034.
32. + T cells in vivo. Proc. Natl. Acad. Sci. USA 103: 147-152.
33. + T cells enter reactive lymph nodes and kill dendritic cells. Nat. Immunol. 8: 743-752.
34. + T cells in vivo: implications for adaptive immunotherapy. Eur. J. Immunol. 31: 1772-1779.
35. Montoya, C. J., H. B. Jie, L. Al-Harthi, C. Mulder, P. J. Patino, M. T. Rugeles, A. M. Krieg, A. L. Landay, and S. B. Wilson. 2006. Activation of plasmacytoid dendritic cells with TLR9 agonists initiates invariant NKT cell-mediated cross-talk with myeloid dendritic cells. J. Immunol. 177: 1028-1039. (Pubitemid 44036605)
36. Cao, W., D. B. Rosen, T. Ito, L. Bover, M. Bao, G. Watanabe, Z. Yao, L. Zhang, L. L. Lanier, and Y. J. Liu. 2006. Plasmacytoid dendritic cell-specific receptor ILT7-Fc1RI inhibits Toll-like receptor-induced interferon production. J. Exp. Med. 203: 1399-1405. (Pubitemid 43877601)
37. Lo, W. F., A. S. Woods, A. DeCloux, R. J. Cotter, E. S. Metcalf, and M. J. Soloski. 2000. Molecular mimicry mediated by MHC class Ib molecules after infection with Gram-negative pathogens. Nat. Med. 6: 215-218. (Pubitemid 30082369)
38. Borg, N. A., K. S. Wun, L. Kjer-Nielsen, M. C. Wilce, D. G. Pellicci, R. Koh, G. S. Besra, M. Bharadwaj, D. I. Godfrey, J. McCluskey, and J. Rossjohn. 2007. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 448: 44-49. (Pubitemid 47037002)
39. Wu, D., G. W. Xing, M. A. Poles, A. Horowitz, Y. Kinjo, B. Sullivan, V. Bodmer-Narkevitch, O. Plettenburg, M. Kronenberg, M. Tsuji, et al. 2005. Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells. Proc. Natl. Acad. Sci. USA 102: 1351-1356. (Pubitemid 40209173)
40. Mattner, J., K. L. Debord, N. Ismail, R. D. Goff, C. Cantu, III, D. Zhou, P. Saint-Mezard, V. Wang, Y. Gao, N. Yin, et al. 2005. Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 434: 525-529. (Pubitemid 40477062)
41. Hansen, T. H., S. Huang, P. L. Arnold, and D. H. Fremont. 2007. Patterns of nonclassical MHC antigen presentation. Nat. Immunol. 8: 563-568. (Pubitemid 46785119)
42. Ochando, J. C., C. Homma, Y. Yang, A. Hidalgo, A. Garin, F. Tacke, V. Angeli, Y. Li, P. Boros, Y. Ding, et al. 2006. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat. Med. 7: 652-662. (Pubitemid 43797347)
43. Palucka, A. K., J. P. Blanck, L. Bennett, V. Pascual, and J. Banchereau. 2005. Cross-regulation of TNF and IFN-α in autoimmune diseases. Proc. Natl. Acad. Sci. USA 102: 3372-3377. (Pubitemid 40328052)
44. + DC, with a plasmacytoid phenotype, induce differentiation and support function of T cells with regulatory properties. Immunology 108: 481-492.
45. Chang, C., and J. F. Miller. 2006. Campylobacter jejuni colonization of mice with limited enteric flora. Infect. Immun. 74: 5261-5271. (Pubitemid 44300445)
46. Ziegler, S. F. 2006. FOXP3: of mice and men. Annu. Rev. Immunol. 24: 209-226.
47. Izcue, A., J. L. Coombes, and F. Powrie. 2006. Regulatory T cells suppress systemic and mucosal immune activation to control intestinal inflammation. Immunol. Rev. 212: 256-271. (Pubitemid 44116713)
48. Weaver, C. T., L. E. Harrington, P. R. Mangan, M. Gavrieli, and K. M. Murphy. 2006. Th17: an effector CD4 T cell lineage with regulatory T cell ties. Immunity 24: 677-688. (Pubitemid 43867371)
49. Uhlig, H. H., B. S. McKenzie, S. Hue, C. Thompson, B. Joyce-Shaikh, R. Stepankova, N. Robinson, S. Buonocore, H. Tlaskalova-Hogenova, D. J. Cua, and F. Powrie. 2006. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology. Immunity 25: 309-318. (Pubitemid 44240502)
50. Vlad, G., R. Cortesini, and N. Suciu-Foca. 2005. License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC. J. Immunol. 174: 5907-5914. (Pubitemid 40663774)
51. Wingender, G., N. Garbi, B. Schumak, F. Jungerkes, E. Endl, D. von Bubnoff, J. Steitz, J. Striegler, G. Moldenhauer, T. Tuting, et al. 2006. Systemic application of CpG-rich DNA suppresses adaptive T cell immunity via induction of IDO. Eur. J. Immunol. 36: 12-20. (Pubitemid 43116387)
52. Katakura, K., J. Lee, D. Rachmilewitz, G. Li, L. Eckmann, and E. Raz. 2005. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J. Clin. Invest. 115: 695-702. (Pubitemid 40322244)
53. Obermeier, F., N. Dunger, U. G. Strauch, C. Hofmann, A. Bleich, N. Grunwald, H. J. Hedrich, E. Aschenbrenner, B. Schlegelberger, G. Rogler, et al. 2005. CpG motifs of bacterial DNA essentially contribute to the perpetuation of chronic intestinal inflammation. Gastroenterology 129: 913-927. (Pubitemid 41242684)
54. + T cell colitis through interaction with regulatory T cell subsets. Proc. Natl. Acad. Sci. USA 102: 2010-2015.