Solution structure of kurtoxin: A gating modifier selective for Cav3 voltage-gated Ca 2+ channels

Biochemistry

Volumn 51, Issue 9, 2012, Pages 1862-1873

  Lee, Chul Won ^a,b   Bae, Chanhyung ^a   Lee, Jaeho ^a   Ryu, Jae Ha ^a   Kim, Ha Hyung ^c   Kohno, Toshiyuki ^d   Swartz, Kenton J ^e   Kim, Jae Il ^a  

^a Gwangju Institute of Science and Technology (GIST)   (South Korea)

^b Chonnam National University   (South Korea)

^c Chung Ang University   (South Korea)

^d KITASATO UNIVERSITY   (Japan)

^e NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID POLYPEPTIDE; BACKBONE STRUCTURES; C-TERMINAL SEGMENTS; DISULFIDE BONDS; HIGH AFFINITY; HYDROPHOBIC SURFACES; PEPTIDE LIGAND; SOLUTION STRUCTURES; SURFACE PROFILES;

AMINO ACIDS; CALCIUM; COVALENT BONDS; METABOLITES; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SIMULATED ANNEALING; SURFACE CHEMISTRY; SURFACE PROPERTIES;

TOXIC MATERIALS;

ALANINE; ALPHA TOXIN; ASPARTIC ACID; CAVEOLIN 3; CYSTEINE; GLYCINE; ISOLEUCINE; KURTOXIN; LEUCINE; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED CALCIUM CHANNEL;

ALPHA HELIX; ARTICLE; BETA SHEET; CALCULATION; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CHEMICAL STRUCTURE; CONTROLLED STUDY; DISULFIDE BOND; DYNAMICAL SIMULATED ANNEALING CALCULATION; HYDROPHOBICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POISONOUS SCORPION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; SIMULATION; SURFACE PROPERTY; TOXIN STRUCTURE;

ANIMALS; CALCIUM CHANNELS; CRYSTALLOGRAPHY, X-RAY; ION CHANNEL GATING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; PEPTIDES; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SCORPION VENOMS; SOLUTIONS;

PARABUTHUS TRANSVAALICUS; SCORPIONES;

EID: 84863288252     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi201633j     Document Type: Article

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