α-Mangostin induces apoptosis and suppresses differentiation of 3T3-L1 cells via inhibiting fatty acid synthase

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Quan, Xiaofang ^a   Wang, Yi ^a   Ma, Xiaofeng ^a   Liang, Yan ^a   Tian, Weixi ^a   Ma, Qingyun ^b   Jiang, Hezhong ^c   Zhao, Youxing ^b  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^b INSTITUTE OF TROPICAL BIOSCIENCE AND BIOTECHNOLOGY   (China)

^c KUNMING INSTITUTE OF BOTANY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA MANGOSTIN; FATTY ACID SYNTHASE; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG; AZO COMPOUND; MANGOSTIN; OIL RED O; PALMITIC ACID DERIVATIVE; PIBENZIMOL; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; XANTHONE DERIVATIVE;

ADIPOCYTE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; CELL STRAIN 3T3; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; LIPID STORAGE; LIPOGENESIS; LIPOLYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOSIS INHIBITION; MOUSE; NONHUMAN; ANALYSIS OF VARIANCE; ANIMAL; CHROMATIN ASSEMBLY AND DISASSEMBLY; DRUG ANTAGONISM; DRUG EFFECT; IC 50;

GARCINIA MANGOSTANA;

3T3-L1 CELLS; ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; AZO COMPOUNDS; BISBENZIMIDAZOLE; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; CHROMATIN ASSEMBLY AND DISASSEMBLY; FATTY ACID SYNTHETASE COMPLEX; INHIBITORY CONCENTRATION 50; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; PALMITIC ACIDS; TETRAZOLIUM SALTS; THIAZOLES; XANTHONES;

EID: 84863264712     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033376     Document Type: Article

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