α-Mangostin Suppresses Phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 Expressions via αvβ3 Integrin/FAK/ERK and NF-κB Signaling Pathway in Human Lung Adenocarcinoma A549 Cells

Cell Biochemistry and Biophysics

Volumn 58, Issue 1, 2010, Pages 31-44

  Shih, Yuan Wei ^a   Chien, Shang Tao ^b   Chen, Pin Shern ^c   Lee, Jian Hui ^a   Wu, Shu Hau ^a   Yin, Li Te ^a  

^a CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^b KAOHSIUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Mangostin; v 3 Integrin; ERK1 2; FAK; Invasion; Migration; MMP 2; MMP 9; PMA

Indexed keywords

FOCAL ADHESION KINASE 1; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MANGOSTIN; MAPK1 PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHORBOL 13 ACETATE 12 MYRISTATE; PTK2 PROTEIN, HUMAN; SMALL INTERFERING RNA; VITRONECTIN RECEPTOR; XANTHONE DERIVATIVE;

ADENOCARCINOMA; ARTICLE; BIOSYNTHESIS; CELL MOTION; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; HUMAN; LUNG TUMOR; METABOLISM; METASTASIS; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; WESTERN BLOTTING;

ADENOCARCINOMA; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL MOVEMENT; FOCAL ADHESION KINASE 1; HUMANS; INTEGRIN ALPHAVBETA3; LUNG NEOPLASMS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NEOPLASM METASTASIS; NF-KAPPA B; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TETRADECANOYLPHORBOL ACETATE; XANTHONES;

EID: 77955665296     PISSN: 10859195     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12013-010-9091-2     Document Type: Article

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