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Volumn 8, Issue 10, 2012, Pages 2915-2923

Multidrug resistance protein P-glycoprotein does not recognize nanoparticle C 60: Experiment and modeling

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONAL CHANGE; DEFENSE RESPONSE; IN-VITRO; INHIBITION ASSAYS; MOLECULAR DYNAMICS SIMULATIONS; MULTIDRUG RESISTANCE; P-GLYCOPROTEIN; RADIUS OF GYRATION; SMALL MOLECULES; THEORETICAL SIMULATION; XENOBIOTIC COMPOUNDS;

EID: 84863229941     PISSN: 1744683X     EISSN: 17446848     Source Type: Journal    
DOI: 10.1039/c2sm06811g     Document Type: Article
Times cited : (54)

References (52)
  • 1
    • 0037162803 scopus 로고    scopus 로고
    • Mechanisms of adaptation in a predator-prey arms race: TTX-resistant sodium channels
    • DOI 10.1126/science.1074310
    • S. Geffeney E. D. Brodie P. C. Ruben E. D. Brodie Mechanisms of adaptation in a predator-prey arms race: TTX-resistant sodium channels Science 2002 297 5585 1336 1339 (Pubitemid 34913169)
    • (2002) Science , vol.297 , Issue.5585 , pp. 1336-1339
    • Geffeney, S.1    Brodie Jr., E.D.2    Ruben, P.C.3    Brodie III, E.D.4
  • 2
    • 0033958086 scopus 로고    scopus 로고
    • Multiple physiological functions for multidrug transporter P-glycoprotein?
    • DOI 10.1016/S0968-0004(99)01493-0, PII S0968000499014930
    • R. W. Johnstone A. A. Ruefli M. J. Smyth Multiple physiological functions for multidrug transporter P-glycoprotein? Trends Biochem. Sci. 2000 25 1 1 6 (Pubitemid 30060419)
    • (2000) Trends in Biochemical Sciences , vol.25 , Issue.1 , pp. 1-6
    • Johnstone, R.W.1    Ruefli, A.A.2    Smyth, M.J.3
  • 5
    • 0023006005 scopus 로고
    • Isolation and expression of a complementary DNA that confers multidrug resistance
    • DOI 10.1038/323728a0
    • P. Gros Y. B. Ben Neriah J. M. Croop D. E. Housman Isolation and expression of a complementary DNA that confers multidrug resistance Nature 1986 323 728 731 (Pubitemid 17172974)
    • (1986) Nature , vol.323 , Issue.6090 , pp. 728-731
    • Gros, P.1    Ben Neriah, Y.2    Croop, J.M.3    Housman, D.E.4
  • 6
    • 0023019651 scopus 로고
    • Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance
    • DOI 10.1038/324485a0
    • J. H. Gerlach J. A. Endicott P. F. Juranka G. Henderson F. Sarangi K. L. DeucAars V. Ling Homology between P-glycoprotein and a bacterial haemolysin transport protein suggests a model for multidrug resistance Nature 1986 324 485 489 (Pubitemid 17184171)
    • (1986) Nature , vol.324 , Issue.6096 , pp. 485-489
    • Gerlach, J.H.1    Endicott, J.A.2    Juranka, P.F.3
  • 7
    • 79951682470 scopus 로고    scopus 로고
    • Influence of P-glycoprotein on embryotoxicity of the antifouling 4 biocides to sea urchin (Strongylocentrotus intermedius)
    • X. Xu J. Fu H. Wang B. Zhang X. Wang Yh. Wang Influence of P-glycoprotein on embryotoxicity of the antifouling 4 biocides to sea urchin (Strongylocentrotus intermedius) Ecotoxicology 2011 20 2 419 428
    • (2011) Ecotoxicology , vol.20 , Issue.2 , pp. 419-428
    • Xu, X.1    Fu, J.2    Wang, H.3    Zhang, B.4    Wang, X.5    Wang, Yh.6
  • 9
    • 20444403742 scopus 로고    scopus 로고
    • Classification of substrates and inhibitors of P-glycoprotein using unsupervised machine learning approach
    • DOI 10.1021/ci050041k
    • Y. H. Wang Y. Li S. L. Yang L. Yang Classification of substrates and inhibitors of P-glycoprotein using unsupervised machine learning approach J. Chem. Inf. Model. 2005 45 3 750 757 (Pubitemid 40795178)
    • (2005) Journal of Chemical Information and Modeling , vol.45 , Issue.3 , pp. 750-757
    • Wang, Y.-H.1    Li, Y.2    Yang, S.-L.3    Yang, L.4
  • 12
    • 65549103248 scopus 로고    scopus 로고
    • Potential health impact of nanoparticles
    • T. Xia N. Li A. E. Nel Potential health impact of nanoparticles Annu. Rev. Public Health 2009 30 137 150
    • (2009) Annu. Rev. Public Health , vol.30 , pp. 137-150
    • Xia, T.1    Li, N.2    Nel, A.E.3
  • 13
    • 77951541621 scopus 로고    scopus 로고
    • The biological mechanisms and physicochemical characteristics responsible for driving fullerene toxicity
    • H. J. Johnston G. R. Hutchison F. M. Christensen K. Aschberger V. Stone The biological mechanisms and physicochemical characteristics responsible for driving fullerene toxicity Toxicol. Sci. 2010 114 2 162 182
    • (2010) Toxicol. Sci. , vol.114 , Issue.2 , pp. 162-182
    • Johnston, H.J.1    Hutchison, G.R.2    Christensen, F.M.3    Aschberger, K.4    Stone, V.5
  • 15
    • 5644267981 scopus 로고    scopus 로고
    • Chemistry and nanoparticulate compositions of a 10,000 year-old ice core melt water
    • DOI 10.1016/j.watres.2004.08.010, PII S0043135404004063
    • L. E. Murr E. V. Esquivel J. J. Bang G. de la Rosa J. L. Gardea-Torresdey Chemistry and nanoparticulate compositions of a 10,000 year-old ice core melt water Water Res. 2004 38 4282 4296 (Pubitemid 39370938)
    • (2004) Water Research , vol.38 , Issue.19 , pp. 4282-4296
    • Murr, L.E.1    Esquivel, E.V.2    Bang, J.J.3    De La Rosa, G.4    Gardea-Torresdey, J.L.5
  • 16
    • 14944383798 scopus 로고    scopus 로고
    • The evolving role of natural products in drug discovery
    • DOI 10.1038/nrd1657
    • F. E. Koehn G. T. Carter The evolving role of natural products in drug discovery Nat. Rev. Drug Discovery 2005 4 206 220 (Pubitemid 40372555)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.3 , pp. 206-220
    • Koehn, F.E.1    Carter, G.T.2
  • 17
    • 77950160186 scopus 로고    scopus 로고
    • P-Glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human Leukemia cells
    • R. B. Li R'A Wu L. Zhao M. H. Wu L. Yang H. F. Zou P-Glycoprotein antibody functionalized carbon nanotube overcomes the multidrug resistance of human Leukemia cells ACS Nano 2010 4 3 1399 1408
    • (2010) ACS Nano , vol.4 , Issue.3 , pp. 1399-1408
    • Li, R.B.1    Wu, R.2    Zhao, L.3    Wu, M.H.4    Yang, L.5    Zou, H.F.6
  • 19
    • 0042622380 scopus 로고    scopus 로고
    • SWISS-MODEL: An automated protein homology-modeling server
    • DOI 10.1093/nar/gkg520
    • T. Schwede J. Kopp N. Guex M. C. Peitsch SWISS-MODEL: An automated protein homology-modeling server Nucleic Acids Res. 2003 31 3381 3385 (Pubitemid 37442164)
    • (2003) Nucleic Acids Research , vol.31 , Issue.13 , pp. 3381-3385
    • Schwede, T.1    Kopp, J.2    Guex, N.3    Peitsch, M.C.4
  • 21
    • 0001008704 scopus 로고
    • Molecular dynamics simulation of a bilayer of 200 lipids in the gel and in the liquid crystal-phases
    • H. Heller M. Schaefer K. Schulten Molecular dynamics simulation of a bilayer of 200 lipids in the gel and in the liquid crystal-phases J. Phys. Chem. 1993 97 8343 8360
    • (1993) J. Phys. Chem. , vol.97 , pp. 8343-8360
    • Heller, H.1    Schaefer, M.2    Schulten, K.3
  • 22
    • 0035170817 scopus 로고    scopus 로고
    • Electrostatics and the gating pore of Shaker potassium channels
    • DOI 10.1085/jgp.117.1.69
    • L. Islas F. Sigworth Electrostatics and the gating pore of shaker potassium channels J. Gen. Physiol. 2001 117 69 89 (Pubitemid 32061907)
    • (2001) Journal of General Physiology , vol.117 , Issue.1 , pp. 69-89
    • Islas, L.D.1    Sigworth, F.J.2
  • 25
    • 33751391901 scopus 로고
    • 60 in the gas and solid phases
    • 60 in the gas and solid phases J. Phys. Chem. 1992 96 858 861
    • (1992) J. Phys. Chem. , vol.96 , pp. 858-861
    • Girifalco, L.A.1
  • 27
    • 0242593434 scopus 로고    scopus 로고
    • Development and current status of the CHARMM force field for nucleic acids
    • DOI 10.1002/1097-0282(2000)56:4<257::AID-BIP10029>3.0.CO;2-W
    • A. D. MacKerell N. Banavali N. Foloppe Development and current status of the CHARMM force field for nucleic acids Biopolymers 2000 56 257 265 (Pubitemid 34105873)
    • (2000) Biopolymers , vol.56 , Issue.4 , pp. 257-265
    • MacKerell Jr., A.D.1    Banavali, N.2    Foloppe, N.3
  • 28
    • 3142714765 scopus 로고    scopus 로고
    • Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations
    • A. D. MacKerell Jr. M. Feig C. L. Brooks III Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations J. Comput. Chem. 2004 25 1400 1415
    • (2004) J. Comput. Chem. , vol.25 , pp. 1400-1415
    • MacKerell, Jr.A.D.1    Feig, M.2    Brooks Iii, C.L.3
  • 30
    • 33646940952 scopus 로고
    • Numerical integration of the cartesian equations of motion of a system with constraints: Molecular dynamics of n-alkanes
    • J. P. Ryckaert G. Ciccotti H. J. C. Berendsen Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes J. Comput. Phys. 1977 23 327 341
    • (1977) J. Comput. Phys. , vol.23 , pp. 327-341
    • Ryckaert, J.P.1    Ciccotti, G.2    Berendsen, H.J.C.3
  • 31
    • 48749148224 scopus 로고
    • Rattle: A "velocity" version of the shake algorithm for molecular dynamics calculations
    • H. C. Andersen Rattle: a "velocity" version of the shake algorithm for molecular dynamics calculations J. Comput. Phys. 1983 52 24 34
    • (1983) J. Comput. Phys. , vol.52 , pp. 24-34
    • Andersen, H.C.1
  • 32
    • 36849093466 scopus 로고    scopus 로고
    • Quantification of fullerenes by LC/ESI-MS and its application to in vivo toxicity assays
    • DOI 10.1021/ac0712289
    • C. W. Isaacson C. Y. Usenko R. L. Tanguay J. A. Field Quantification of fullerenes by LC/ESI-MS and its application to in vivo toxicity assays Anal. Chem. 2007 79 9091 9097 (Pubitemid 350231720)
    • (2007) Analytical Chemistry , vol.79 , Issue.23 , pp. 9091-9097
    • Isaacson, C.W.1    Usenko, C.Y.2    Tanguay, R.L.3    Field, J.A.4
  • 33
    • 0034998230 scopus 로고    scopus 로고
    • Insertion of fluorescent fatty acid probes into the outer membranes of the pathogenic spirochaetes Treponema pallidum and Borrelia burgdorferi
    • D. L. Cox J. D. Radolf Insertion of fluorescent fatty acid probes into the outer membranes of the pathogenic spirochaetes Treponema pallidum and Borrelia burgdorferi Microbiology 2001 147 1161 1169 (Pubitemid 32454634)
    • (2001) Microbiology , vol.147 , Issue.5 , pp. 1161-1169
    • Cox, D.L.1    Radolf, J.D.2
  • 34
    • 0033862088 scopus 로고    scopus 로고
    • Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines
    • DOI 10.1016/S0928-0987(00)00097-X, PII S092809870000097X
    • I. C. van der Sandt M. C. Blom-Roosemalen A. G. de Boer D. D. Breimer Specificity of doxorubicin versus rhodamine-123 in assessing P-glycoprotein functionality in the LLC-PK1, LLC-PK1:MDR1 and Caco-2 cell lines Eur. J. Pharm. Sci. 2000 11 207 214 (Pubitemid 30616443)
    • (2000) European Journal of Pharmaceutical Sciences , vol.11 , Issue.3 , pp. 207-214
    • Van Der Sandt, I.C.J.1    Blom-Roosemalen, M.C.M.2    De Boer, A.G.3    Breimer, D.D.4
  • 35
    • 14044265064 scopus 로고    scopus 로고
    • Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes
    • DOI 10.1124/dmd.104.001669
    • P. P. Annaert K. L. R. Brouwer Assessment of drug interactions in hepatobiliary transport using Rhodamine-123 in sandwich-cultured rat hepatocytes Drug Metab. Dispos. 2004 33 3 388 394 (Pubitemid 40279939)
    • (2005) Drug Metabolism and Disposition , vol.33 , Issue.3 , pp. 388-394
    • Annaert, P.P.1    Brouwer, K.L.R.2
  • 38
    • 24144490885 scopus 로고    scopus 로고
    • Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention
    • DOI 10.1021/mp050032z
    • S. K. Sahoo V. Labhasetwar Enhanced antiproliferative activity of transferrin-conjugated paclitaxel-loaded nanoparticles is mediated via sustained intracellular drug retention Mol. Pharmaceutics 2005 2 373 383 (Pubitemid 41503678)
    • (2005) Molecular Pharmaceutics , vol.2 , Issue.5 , pp. 373-383
    • Sahoo, S.K.1    Labhasetwar, V.2
  • 41
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • M. M. Gottesman T. Fojo S. E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2002 2 48 58 (Pubitemid 37328807)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.1 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 44
    • 35148834736 scopus 로고    scopus 로고
    • Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1). II. Clinical aspects
    • DOI 10.1016/j.drudis.2007.07.021, PII S1359644607003005
    • A. Aszalos Drug-drug interactions affected by the transporter protein, P-glycoprotein (ABCB1, MDR1): II. Clinical aspects Drug Discovery Today 2007 12 19-20 838 843 (Pubitemid 47539962)
    • (2007) Drug Discovery Today , vol.12 , Issue.19-20 , pp. 838-843
    • Aszalos, A.1
  • 45
    • 0030782511 scopus 로고    scopus 로고
    • Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
    • A. B. Shapiro V. Ling Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificitie Eur. J. Biochem. 1997 250 130 137 (Pubitemid 27504592)
    • (1997) European Journal of Biochemistry , vol.250 , Issue.1 , pp. 130-137
    • Shapiro, A.B.1    Ling, V.2
  • 46
    • 79951778220 scopus 로고    scopus 로고
    • Two TPX2-dependent switches control the activity of Aurora A
    • X. Xu X. Wang Z. Xiao Y. Li Yh Wang Two TPX2-dependent switches control the activity of Aurora A Plos one 2011 6 2 1 7
    • (2011) Plos One , vol.6 , Issue.2 , pp. 1-7
    • Xu, X.1    Wang, X.2    Xiao, Z.3    Li, Y.4    Wang, Y.5
  • 47
    • 79952456642 scopus 로고    scopus 로고
    • Dynamic communication between androgen and coactivator: Mutually induced conformational perturbations in androgen receptor ligand-binding domain
    • X. Xu W. Yang X. Wang Y. Li Y. Wang C. Ai Dynamic communication between androgen and coactivator: mutually induced conformational perturbations in androgen receptor ligand-binding domain Proteins: Struct., Funct., Bioinf. 2011 79 4 1154 1171
    • (2011) Proteins: Struct., Funct., Bioinf. , vol.79 , Issue.4 , pp. 1154-1171
    • Xu, X.1    Yang, W.2    Wang, X.3    Li, Y.4    Wang, Y.5    Ai, C.6
  • 48
    • 34548814998 scopus 로고    scopus 로고
    • Substrate-induced Conformational Changes and Dynamics of UDP-N-Acetylgalactosamine:Polypeptide N-Acetylgalactosaminyltransferase-2
    • DOI 10.1016/j.jmb.2007.08.028, PII S0022283607010996
    • A. L. Milac1 N. V. Buchete T. A. Fritz1 G. Hummer L. A. Tabak Substrate-induced conformational changes and dynamics of UDP-N- Acetylgalactosamine: Polypeptide N-Acetylgalactosaminyltransferase-2 J. Mol. Biol. 2007 373 439 451 (Pubitemid 47445582)
    • (2007) Journal of Molecular Biology , vol.373 , Issue.2 , pp. 439-451
    • Milac, A.L.1    Buchete, N.V.2    Fritz, T.A.3    Hummer, G.4    Tabak, L.A.5
  • 49
    • 0035813143 scopus 로고    scopus 로고
    • Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linkers as molecular rulers
    • T. W. Loo D. M. Clarke Determining the dimensions of the drug-binding domain of human P-glycoprotein using thiol cross-linkers as molecular rulers J. Biol. Chem. 2001 276 36877 36880
    • (2001) J. Biol. Chem. , vol.276 , pp. 36877-36880
    • Loo, T.W.1    Clarke, D.M.2
  • 50
    • 0346096509 scopus 로고    scopus 로고
    • An ABC transporter with a secondary-active multidrug translocator domain
    • DOI 10.1038/nature02173
    • H. Venter R. A. Shilling S. Velamakanni L. Balakrishnan H. W. Van Veen An ABC transporter with a secondary-active multidrug translocator domain Nature 2003 426 866 870 (Pubitemid 38056875)
    • (2003) Nature , vol.426 , Issue.6968 , pp. 866-870
    • Venter, H.1    Shilling, R.A.2    Velamakanni, S.3    Balakrishnan, L.4    Van Veen, H.W.5
  • 51
    • 4444266487 scopus 로고    scopus 로고
    • The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes
    • J. A. Sheps S. Ralph Z. Zhao D. L. Baillie V. Ling The ABC transporter gene family of Caenorhabditis elegans has implications for the evolutionary dynamics of multidrug resistance in eukaryotes GenomeBiology 2004 5 3 R15
    • (2004) GenomeBiology , vol.5 , Issue.3 , pp. 15
    • Sheps, J.A.1    Ralph, S.2    Zhao, Z.3    Baillie, D.L.4    Ling, V.5
  • 52
    • 24944575366 scopus 로고    scopus 로고
    • Tumorigenesis: The adaptation of mammalian cells to sustained stress environment by epigenetic alterations and succeeding matched mutations
    • DOI 10.1093/carcin/bgi079
    • T. V. Karpinets B. D. Foy Tumorigenesis: the adaptation of mammalian cells to sustained stress environment by epigenetic alterations and succeeding matched mutations Carcinogenesis 2005 26 8 1323 1334 (Pubitemid 41417874)
    • (2005) Carcinogenesis , vol.26 , Issue.8 , pp. 1323-1334
    • Karpinets, T.V.1    Foy, B.D.2


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