Ginsenoside Rg1 attenuates lipopolysaccharide-induced inflammatory responses via the phospholipase c-γ1 signaling pathway in murine BV-2 microglial cells

Current Medicinal Chemistry

Volumn 19, Issue 5, 2012, Pages 770-779

  Zong, Y ^a   Ai, Q L ^b   Zhong, L M ^b   Dai, J N ^a   Yang, P ^a   He, Y ^a   Sun, J ^a   Ling, E A ^c   Lu, D ^a  

^a KUNMING MEDICAL UNIVERSITY   (China)

^b Medical University   (China)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

BV 2 cells; C Jun N terminal protein kinase; Cyclic AMP responsive element (CRE) binding protein; Cyclooxygenase 2; Extracellular signal regulated kinase1 2; Ginsenoside Rg1; Inducible nitric oxide synthase; Inhibitor B ; Interleukin 1 ; Lipopolysaccharide; Mitogen activated protein kinases; Nuclear factor B; P38 mitogen activated protein kinase; Phospholipase C 1; Tumor necrosis factor

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOOXYGENASE 2; CYTOKINE; GINSENOSIDE RG 1; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOLIPASE C GAMMA1; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; ENZYME INHIBITION; IMMUNOFLUORESCENCE TEST; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CELL LINE; CENTRAL NERVOUS SYSTEM AGENTS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; GINSENOSIDES; INFLAMMATION; LIPOPOLYSACCHARIDES; MICE; MICROGLIA; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

EID: 84863229657     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712798992066     Document Type: Article

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