Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis

Oncogene

Volumn 31, Issue 26, 2012, Pages 3202-3212

  Derocq, D ^a,b,c   Prebois C ^a,b,c   Beaujouin, M ^a,b,c   Laurent Matha, V ^a,b,c   Pattingre, S ^a,b,c   Smith, G K ^d   Liaudet Coopman, E ^a,b,c  

^a INSTITUT DE RECHERCHE EN CANCÉROLOGIE DE MONTPELLIER   (France)

^b CENTRE VAL D AURELLE   (France)

^c UNIV MONTPELLIER   (France)

^d GLAXOSMITHKLINE   (United States)

Author keywords

cancer; cathepsin D; endocytosis; LRP1; RIP; tyrosine phosphorylation

Indexed keywords

CATHEPSIN D; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN;

ARTICLE; BETA CHAIN; CONTROLLED STUDY; ENDOCYTOSIS; FIBROBLAST; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; REGULATED INTRAMEMBRANE PROTEOLYSIS;

ANIMALS; BREAST NEOPLASMS; CATHEPSIN D; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOCYTOSIS; ENZYME PRECURSORS; FIBROBLASTS; HUMANS; LOW DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN-1; MAMMARY GLANDS, HUMAN; NEOPLASM INVASIVENESS; PROTEIN STRUCTURE, TERTIARY; PROTEOLYSIS; TUMOR MICROENVIRONMENT;

EID: 84863227600     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.501     Document Type: Article

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