Cell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function

FASEB Journal

Volumn 25, Issue 8, 2011, Pages 2770-2781

  Selvais, Charlotte ^a   D'Auria, Ludovic ^a   Tyteca, Donatienne ^a   Perrot, Gwenn ^b   Lemoine, Pascale ^a   Troeberg, Linda ^c   Dedieu, Steṕhane ^b   Noël, Agnes̀ ^d   Nagase, Hideaki ^c   Henriet, Patrick ^a   Courtoy, Pierre J ^a   Marbaix, Etienne ^a   Emonard, Hervé ^b  

^a DE DUVE INSTITUTE   (Belgium)

^b UNIVERSITÉ DE REIMS CHAMPAGNE ARDENNE   (France)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

ADAM; Endocytosis; MMP; Plasma membrane; Raft

Indexed keywords

A DISINTEGRIN AND METALLOPROTEINASE 12; ADAM PROTEIN; CHOLESTEROL; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; MATRIX METALLOPROTEINASE; METALLOPROTEINASE; RNA; SMALL INTERFERING RNA; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; CELL CULTURE; CELL MEMBRANE; ENDOCYTOSIS; FIBROSARCOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DEGRADATION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADAM PROTEINS; ANTIGENS, CD; BASE SEQUENCE; CELL LINE, TUMOR; CELL MEMBRANE; CHOLESTEROL; EPITHELIOID CELLS; FIBROBLASTS; HUMANS; LDL-RECEPTOR RELATED PROTEIN 1; MATRIX METALLOPROTEINASE 14; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MEMBRANE PROTEINS; METALLOPROTEASES; PROTEIN STRUCTURE, TERTIARY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 80051685667     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.10-169508     Document Type: Article

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