메뉴 건너뛰기




Volumn 67, Issue 10, 2008, Pages 1461-1467

Amelioration of human lupus-like phenotypes in MRL/lpr mice by overexpression of interleukin 27 receptor α(WSX-1)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA ANTIBODY; GAMMA INTERFERON; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G2A; INTERLEUKIN 27; INTERLEUKIN 27 RECEPTOR ALPHA; INTERLEUKIN 4; INTERLEUKIN RECEPTOR; MESSENGER RNA; STAT3 PROTEIN; UNCLASSIFIED DRUG;

EID: 53149133918     PISSN: 00034967     EISSN: None     Source Type: Journal    
DOI: 10.1136/ard.2007.077537     Document Type: Article
Times cited : (50)

References (30)
  • 1
    • 18444385868 scopus 로고    scopus 로고
    • IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
    • Pflanz S, Timans JC, Cheung J, Rosales R, Kanzler H, Gilbert J, et al. IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity 2002;16:779-90.
    • (2002) Immunity , vol.16 , pp. 779-790
    • Pflanz, S.1    Timans, J.C.2    Cheung, J.3    Rosales, R.4    Kanzler, H.5    Gilbert, J.6
  • 2
    • 0038326688 scopus 로고    scopus 로고
    • Cutting edge: Role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment
    • Takeda A, Hamano S. Yamanaka A, Hanada T, Ishibashi T, Mak TW, et al. Cutting edge: role of IL-27/WSX-1 signaling for induction of T-bet through activation of STAT1 during initial Th1 commitment. J Immunol 2003;170:4886-90.
    • (2003) J Immunol , vol.170 , pp. 4886-4890
    • Takeda, A.1    Hamano, S.2    Yamanaka, A.3    Hanada, T.4    Ishibashi, T.5    Mak, T.W.6
  • 4
    • 10744222574 scopus 로고    scopus 로고
    • WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
    • Pflanz S, Hibbert L, Mattson J. Rosales R, Vaisberg E, Bazan JF, et al. WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J Immunol 2004;172:2225-31.
    • (2004) J Immunol , vol.172 , pp. 2225-2231
    • Pflanz, S.1    Hibbert, L.2    Mattson, J.3    Rosales, R.4    Vaisberg, E.5    Bazan, J.F.6
  • 5
    • 0034687402 scopus 로고    scopus 로고
    • Development of Th 1 - type immune responses requires the type I cytokine receptor TCCR
    • Chen Q, Ghilardi N, Wang H, Baker T, Xie MH, Gurney A, et al. Development of Th 1 - type immune responses requires the type I cytokine receptor TCCR. Nature 2000;407:916-20.
    • (2000) Nature , vol.407 , pp. 916-920
    • Chen, Q.1    Ghilardi, N.2    Wang, H.3    Baker, T.4    Xie, M.H.5    Gurney, A.6
  • 6
    • 17944377950 scopus 로고    scopus 로고
    • Yoshida H, Hamano S, Senaldi G, Covey T, Faggioni R, Mu S, et al. WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. Immunity 2001;15:569-78.
    • Yoshida H, Hamano S, Senaldi G, Covey T, Faggioni R, Mu S, et al. WSX-1 is required for the initiation of Th1 responses and resistance to L. major infection. Immunity 2001;15:569-78.
  • 7
    • 6344274850 scopus 로고    scopus 로고
    • The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity
    • Artis D, Villarino A, Silverman M, He W, Thornton EM, Mu S, et al. The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity. J Immunol 2004;173:5626-34.
    • (2004) J Immunol , vol.173 , pp. 5626-5634
    • Artis, D.1    Villarino, A.2    Silverman, M.3    He, W.4    Thornton, E.M.5    Mu, S.6
  • 9
    • 10744221849 scopus 로고    scopus 로고
    • WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production
    • Hamano S, Himeno K, Miyazaki Y, Ishii K, Yamanaka A, Takeda A, et al. WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production. Immunity 2003;19:657-67.
    • (2003) Immunity , vol.19 , pp. 657-667
    • Hamano, S.1    Himeno, K.2    Miyazaki, Y.3    Ishii, K.4    Yamanaka, A.5    Takeda, A.6
  • 10
    • 0345570521 scopus 로고    scopus 로고
    • The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection
    • Villarino A, Hibbert L, Lieberman L, Wilson E, Mak T, Yoshida H, et al. The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection. Immunity 2003;19:645-55.
    • (2003) Immunity , vol.19 , pp. 645-655
    • Villarino, A.1    Hibbert, L.2    Lieberman, L.3    Wilson, E.4    Mak, T.5    Yoshida, H.6
  • 11
    • 1542409969 scopus 로고    scopus 로고
    • Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis
    • Yamanaka A, Hamano S, Miyazaki Y, Ishii K, Takeda A, Mak TW, et al. Hyperproduction of proinflammatory cytokines by WSX-1-deficient NKT cells in concanavalin A-induced hepatitis. J Immunol 2004;172: 3590-6.
    • (2004) J Immunol , vol.172 , pp. 3590-3596
    • Yamanaka, A.1    Hamano, S.2    Miyazaki, Y.3    Ishii, K.4    Takeda, A.5    Mak, T.W.6
  • 12
    • 14844355133 scopus 로고    scopus 로고
    • The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis
    • Holscher C, Holscher A, Ruckerl D, Yoshimoto T, Yoshida H, Mak T, et al. The IL-27 receptor chain WSX-1 differentially regulates antibacterial immunity and survival during experimental tuberculosis. J Immunol 2005; 174:3534-44.
    • (2005) J Immunol , vol.174 , pp. 3534-3544
    • Holscher, C.1    Holscher, A.2    Ruckerl, D.3    Yoshimoto, T.4    Yoshida, H.5    Mak, T.6
  • 13
    • 23444445743 scopus 로고    scopus 로고
    • Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice
    • Miyazaki Y, Inoue H, Matsumura M, Matsumoto K, Nakano T, Tsuda M, et al. Exacerbation of experimental allergic asthma by augmented Th2 responses in WSX-1-deficient mice. J Immunol 2005;175:2401-7.
    • (2005) J Immunol , vol.175 , pp. 2401-2407
    • Miyazaki, Y.1    Inoue, H.2    Matsumura, M.3    Matsumoto, K.4    Nakano, T.5    Tsuda, M.6
  • 14
    • 33747588291 scopus 로고    scopus 로고
    • Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
    • Batten M, Li J, Yi S, Kljavin NM, Danilenko DM, Lucas S, et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nature immunology 2006;7:929-36.
    • (2006) Nature immunology , vol.7 , pp. 929-936
    • Batten, M.1    Li, J.2    Yi, S.3    Kljavin, N.M.4    Danilenko, D.M.5    Lucas, S.6
  • 15
    • 33747593830 scopus 로고    scopus 로고
    • Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
    • Stumhofer JS, Laurence A, Wilson EH, Huang E. Tato CM, Johnson LM, et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nature immunology 2006;7:937-45.
    • (2006) Nature immunology , vol.7 , pp. 937-945
    • Stumhofer, J.S.1    Laurence, A.2    Wilson, E.H.3    Huang, E.4    Tato, C.M.5    Johnson, L.M.6
  • 16
    • 33749515631 scopus 로고    scopus 로고
    • Two-sided roles of IL-27: Induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism
    • Yoshimura T, Takeda A, Hamano S. Miyazaki Y. Kinjyo I, Ishibashi T, et al. Two-sided roles of IL-27: induction of Th1 differentiation on naive CD4+ T cells versus suppression of proinflammatory cytokine production including IL-23-induced IL-17 on activated CD4+ T cells partially through STAT3-dependent mechanism. J Immunol 2006;177:5377-85.
    • (2006) J Immunol , vol.177 , pp. 5377-5385
    • Yoshimura, T.1    Takeda, A.2    Hamano, S.3    Miyazaki, Y.4    Kinjyo, I.5    Ishibashi, T.6
  • 17
    • 0014271714 scopus 로고
    • The pathogenesis of glomerulonephritis
    • Dixon FJ. The pathogenesis of glomerulonephritis. Am J Med 1968;44:493-8.
    • (1968) Am J Med , vol.44 , pp. 493-498
    • Dixon, F.J.1
  • 21
    • 0030175603 scopus 로고    scopus 로고
    • Role of Fas-mediated cell death in the regulation of immune responses
    • Van Parijs L, Abbas AK. Role of Fas-mediated cell death in the regulation of immune responses. Curr Opin Immunol 1996;8:355-61.
    • (1996) Curr Opin Immunol , vol.8 , pp. 355-361
    • Van Parijs, L.1    Abbas, A.K.2
  • 22
    • 0022273898 scopus 로고
    • Murine models of systemic lupus erythematosus
    • Theofilopoulos AN, Dixon FJ. Murine models of systemic lupus erythematosus. Adv Immunol 1985;37:269-390.
    • (1985) Adv Immunol , vol.37 , pp. 269-390
    • Theofilopoulos, A.N.1    Dixon, F.J.2
  • 23
    • 28244474156 scopus 로고    scopus 로고
    • Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1)
    • Shimizu S, Sugiyama N, Masutani K, Sadanaga A, Miyazaki Y, Inoue Y, et al. Membranous glomerulonephritis development with Th2-type immune deviations in MRL/lpr mice deficient for IL-27 receptor (WSX-1). J Immunol 2005;175:7185-92.
    • (2005) J Immunol , vol.175 , pp. 7185-7192
    • Shimizu, S.1    Sugiyama, N.2    Masutani, K.3    Sadanaga, A.4    Miyazaki, Y.5    Inoue, Y.6
  • 24
    • 26444605552 scopus 로고    scopus 로고
    • WSX-1 overexpression in CD4(+) T cells leads to hyperproliferation and cytokine hyperproduction in response to TCR stimulation
    • Takeda A. Hamano S. Shiraishi H. Yoshimura T. Ogata H. Ishii K, et al. WSX-1 overexpression in CD4(+) T cells leads to hyperproliferation and cytokine hyperproduction in response to TCR stimulation. Int Immunol 2005;17:889-97.
    • (2005) Int Immunol , vol.17 , pp. 889-897
    • Takeda, A.1    Hamano, S.2    Shiraishi, H.3    Yoshimura, T.4    Ogata, H.5    Ishii, K.6
  • 25
    • 31044440025 scopus 로고    scopus 로고
    • Toll-like receptor 9 signaling protects against murine lupus
    • Wu X, Peng SL. Toll-like receptor 9 signaling protects against murine lupus. Arthritis Rheum 2006;54:336-42.
    • (2006) Arthritis Rheum , vol.54 , pp. 336-342
    • Wu, X.1    Peng, S.L.2
  • 27
    • 33745666235 scopus 로고    scopus 로고
    • Expression of synaptopodin and GLEPPI as markers of steroid responsiveness in primary focal segmental glomerulosclerosis
    • Hirakawa M, Tsuruya K, Yotsueda H, Tokumoto M, Ikeda H, Katafuchi R, et al. Expression of synaptopodin and GLEPPI as markers of steroid responsiveness in primary focal segmental glomerulosclerosis. Life Sci 2006;79:757-63.
    • (2006) Life Sci , vol.79 , pp. 757-763
    • Hirakawa, M.1    Tsuruya, K.2    Yotsueda, H.3    Tokumoto, M.4    Ikeda, H.5    Katafuchi, R.6
  • 28
    • 0025875259 scopus 로고
    • Lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen PL, Eisenberg RA. Lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu Rev Immunol 1991;9:243-69.
    • (1991) Annu Rev Immunol , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 29
    • 33751568890 scopus 로고    scopus 로고
    • IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways
    • Owaki T, Asakawa M, Fukai F, Mizuguchi J, Yoshimoto T. IL-27 induces Th1 differentiation via p38 MAPK/T-bet- and intercellular adhesion molecule-1/LFA-1/ERK1/2-dependent pathways. J Immunol 2006;177:7579-87.
    • (2006) J Immunol , vol.177 , pp. 7579-7587
    • Owaki, T.1    Asakawa, M.2    Fukai, F.3    Mizuguchi, J.4    Yoshimoto, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.