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ChemMedChem

Volumn 7, Issue 7, 2012, Pages 1202-1209

Predicting Drug Metabolism by Cytochrome P450 2C9: Comparison with the 2D6 and 3A4 Isoforms

(2) Rydberg, Patrik a Olsen, Lars a

a UNIVERSITY OF COPENHAGEN (Denmark)

Author keywords

Chemoinformatics; Cytochromes P450; Density functional calculations; Drug metabolism; Heme

Indexed keywords

AMINE; CARBOXYLIC ACID; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; DIARYLAMINE DERIVATIVE; DIVINYLAMINE DERIVATIVE; MALATHION; PHORATE; PHOSPHOROTHIOIC ACID; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; COMPUTER PROGRAM; CRYSTAL STRUCTURE; DESULFURIZATION; DRUG METABOLISM; EMPIRICAL TWO DIMENSIONAL MODEL; METABOLITE DOCKING MODEL; METASITE MODEL; MOLECULAR MODEL; PHARMACOPHORE; PREDICTION; PRIORITY JOURNAL; SCHRODINGER MODEL; SMARTCYP MODEL; SPAN2END MODEL; STARDROP MODEL; X RAY CRYSTALLOGRAPHY;

ARYL HYDROCARBON HYDROXYLASES; CRYSTALLOGRAPHY, X-RAY; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 CYP3A; LIGANDS; MODELS, MOLECULAR; PHARMACEUTICAL PREPARATIONS;

EID: 84862888243 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201200160 Document Type: Article

Times cited : (51)

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