Plasma membrane-associated glycohydrolases activation by extracellular acidification due to proton exchangers

Neurochemical Research

Volumn 37, Issue 6, 2012, Pages 1296-1307

  Aureli, Massimo ^a   Loberto, Nicoletta ^a   Bassi, Rosaria ^a   Ferraretto, Anita ^a   Perego, Silvia ^a   Lanteri, Patrizia ^a   Chigorno, Vanna ^a   Sonnino, Sandro ^a   Prinetti, Alessandro ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Glycoconjugates; Glycohydrolases; Glycolipids; Glycoproteins; Optimal pH; Plasma membranes; Proton modulators

Indexed keywords

BETA GALACTOSIDASE; BETA GLUCOSIDASE GBA2; BETA N ACETYLHEXOSAMINIDASE; CONDURITOL B EPOXIDE SENSITIVE BETA GLUCOSIDASE; GLYCOSIDASE; PROTON; UNCLASSIFIED DRUG;

ACIDIFICATION; ACIDITY; ARTICLE; CELL MEMBRANE; CELL PH; ENZYME ACTIVATION; ENZYME ACTIVITY; GLIOMA CELL; HUMAN; HUMAN CELL; NEUROBLASTOMA CELL; PRIORITY JOURNAL; PROTON TRANSPORT; SKIN FIBROBLAST;

ACETAZOLAMIDE; AMILORIDE; BETA-GALACTOSIDASE; BETA-GLUCOSIDASE; BETA-N-ACETYLHEXOSAMINIDASES; CELL LINE, TUMOR; CELL MEMBRANE; CELLS, CULTURED; EGTAZIC ACID; ENZYME ACTIVATION; FIBROBLASTS; GLIOMA; HUMANS; HYDROGEN-ION CONCENTRATION; NEUROBLASTOMA; OMEPRAZOLE; PROTONS;

EID: 84862871503     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-012-0725-1     Document Type: Article

References (64)

1. Hakomori S (1996) Tumor malignancy defined by aberrant glycosylation and sphingo(glyco)lipid metabolism. Cancer Res 56:5309-5318 (Pubitemid 27011703)
2. Hakomori S (2002) Glycosylation defining cancer malignancy: new wine in an old bottle. Proc Natl Acad Sci USA 99: 10231-10233
3. Dennis JW, Granovsky M, Warren CE (1999) Glycoprotein glycosylation and cancer progression. Biochim Biophys Acta 1473:21-34
4. Traylor TD, Hogan EL (1980) Gangliosides of human cerebral astrocytomas. J Neurochem 34:126-131 (Pubitemid 10172687)
5. Jennemann R, Rodden A, Bauer BL, Mennel HD et al (1990) Glycosphingolipids of human gliomas. Cancer Res 50:7444-7449
6. Shinoura N, Dohi T, Kondo T, Yoshioka M et al (1992) Ganglioside composition and its relation to clinical data in brain tumors. Neurosurgery 31:541-549
7. Pan XL, Izumi T, Yamada H, Akiyoshi K et al (2000) Ganglioside patterns in neuroepithelial tumors of childhood. Brain Dev 22:196-198 (Pubitemid 30256254)
8. Wikstrand CJ, He XM, Fuller GN, Bigner SH et al (1991) Occurrence of lacto series gangliosides 3′-isoLM1 and 3′,6′-isoLD1 in human gliomas in vitro and in vivo. J Neuropathol Exp Neurol 50:756-769
9. Moskal JR, Kroes RA, Dawson G (2009) The glycobiology of brain tumors: disease relevance and therapeutic potential. Expert Rev Neurother 9:1529-1545
10. Meany DL, Chan DW (2011) Aberrant glycosylation associated with enzymes as cancer biomarkers. Clin Proteomics 8:7
11. Guo HB, Lee I, Kamar M, Pierce M (2003) N-acetylglucosaminyltransferase V expression levels regulate cadherinassociated homotypic cell-cell adhesion and intracellular signaling pathways. J Biol Chem 278:52412-52424 (Pubitemid 38035833)
12. Takahashi M, Kuroki Y, Ohtsubo K, Taniguchi N (2009) Core fucose and bisecting GlcNAc, the direct modifiers of the N-glycan core: their functions and target proteins. Carbohydr Res 344:1387-1390
13. Dennis JW, Laferte S, Waghorne C, Breitman ML et al (1987) Beta 1-6 branching of Asn-linked oligosaccharides is directly associated with metastasis. Science 236:582-585 (Pubitemid 17069927)
14. Yamamoto H, Swoger J, Greene S, Saito T et al (2000) Beta1,6-N- acetylglucosamine-bearing N-glycans in human gliomas: implications for a role in regulating invasivity. Cancer Res 60:134-142 (Pubitemid 30058743)
15. Yamamoto H, Oviedo A, Sweeley C, Saito T et al (2001) Alpha2,6-sialylation of cell-surface N-glycans inhibits glioma formation in vivo. Cancer Res 61:6822-6829 (Pubitemid 32896507)
16. Kroes RA, He H, Emmett MR, Nilsson CL et al (2010) Overexpression of ST6GalNAcV, a ganglioside-specific alpha2,6-sialyltransferase, inhibits glioma growth in vivo. Proc Natl Acad Sci USA 107:12646-12651
17. Prinetti A, Chigorno V, Mauri L, Loberto N et al (2007) Modulation of cell functions by glycosphingolipid metabolic remodeling in the plasma membrane. J Neurochem 103(Suppl 1):113-125
18. Aureli M, Loberto N, Chigorno V, Prinetti A et al (2011) Remodeling of sphingolipids by plasma membrane associated enzymes. Neurochem Res 36:1636-1644
19. Valaperta R, Chigorno V, Basso L, Prinetti A et al (2006) Plasma membrane production of ceramide from ganglioside GM3 in human fibroblasts. FASEB J 20:1227-1229
20. Aureli M, Loberto N, Lanteri P, Chigorno V et al (2011) Cell surface sphingolipid glycohydrolases in neuronal differentiation and aging in culture. J Neurochem 116:891-899
21. Miyagi T, Wada T, Yamaguchi K (2008) Roles of plasma membrane-associated sialidase NEU3 in human cancers. Biochim Biophys Acta 1780:532-537 (Pubitemid 351395305)
22. Kakugawa Y, Wada T, Yamaguchi K, Yamanami H et al (2002) Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression. Proc Natl Acad Sci USA 99:10718-10723
23. Wada T, Hata K, Yamaguchi K, Shiozaki K et al (2007) A crucial role of plasma membrane-associated sialidase in the survival of human cancer cells. Oncogene 26:2483-2490 (Pubitemid 46597274)
24. Boot RG, Verhoek M, Donker-Koopman W, Strijland A et al (2007) Identification of the non-lysosomal glucosylceramidase as beta-glucosidase 2. J Biol Chem 282:1305-1312
25. Mencarelli S, Cavalieri C, Magini A, Tancini B et al (2005) Identification of plasma membrane associated mature beta-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts. FEBS Lett 579:5501-5506 (Pubitemid 41455621)
26. Aureli M, Masilamani AP, Illuzzi G, Loberto N et al (2009) Activity of plasma membrane beta-galactosidase and beta-glucosidase. FEBS Lett 583:2469-2473
27. Monti E, Bassi MT, Papini N, Riboni M et al (2000) Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane. Biochem J 349:343-351 (Pubitemid 30440200)
28. van Weely S, Brandsma M, Strijland A, Tager JM et al (1993) Demonstration of the existence of a second, non-lysosomal glucocerebrosidase that is not deficient in Gaucher disease. Biochim Biophys Acta 1181:55-62 (Pubitemid 23087522)
29. + exchangers. Physiol Rev 77:51-74 (Pubitemid 27068802)
30. Halestrap AP, Price NT (1999) The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. Biochem J 343(Pt 2):281-299 (Pubitemid 29511759)
31. Chiche J, Brahimi-Horn MC, Pouyssegur J (2010) Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer. J Cell Mol Med 14:771-794
32. + exchanger in metastasis. Nat Rev Cancer 5:786-795 (Pubitemid 41400778)
33. Izumi H, Torigoe T, Ishiguchi H, Uramoto H et al (2003) Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy. Cancer Treat Rev 29:541-549 (Pubitemid 37428326)
34. + exchange. J Physiol 567:225-238 (Pubitemid 41167317)
35. Reshkin SJ, Bellizzi A, Albarani V, Guerra L et al (2000) Phosphoinositide 3-kinase is involved in the tumor-specific activation of human breast cancer cell Na(+)/H(+) exchange, motility, and invasion induced by serum deprivation. J Biol Chem 275:5361-5369 (Pubitemid 30115166)
36. Overkleeft HS, Renkema GH, Neele J, Vianello P et al (1998) Generation of specific deoxynojirimycin-type inhibitors of the nonlysosomal glucosylceramidase. J Biol Chem 273:26522-26527 (Pubitemid 28471661)
37. Leroy JG, Ho MW, MacBrinn MC, Zielke K et al (1972) I-cell disease: biochemical studies. Pediatr Res 6:752-757
38. Chiche J, Ilc K, Laferriere J, Trottier E et al (2009) Hypoxiainducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 69:358-368
39. Thongon N, Krishnamra N (2011) Omeprazole decreases magnesium transport across Caco-2 monolayers. World J Gastroenterol 17:1574-1583
40. Wong P, Kleemann HW, Tannock IF (2002) Cytostatic potential of novel agents that inhibit the regulation of intracellular pH. Br J Cancer 87:238-245
41. Elliott JT, Tona A, Plant AL (2003) Comparison of reagents for shape analysis of fixed cells by automated fluorescence microscopy. Cytometry A 52:90-100 (Pubitemid 37521507)
42. Yuanbo C, Fan Z, Jiachang Y (2005) Detecting proton flux across chromatophores driven by F0F1-ATPase using N-(fluorescein-5-thiocarbamoyl)-1,2- dihexadecanoyl-sn-glycero-3-phosphoeth anolamine, triethylammonium salt. Anal Biochem 344:102-107 (Pubitemid 41569382)
43. Stock C, Mueller M, Kraehling H, Mally S et al (2007) pH nanoenvironment at the surface of single melanoma cells. Cell Physiol Biochem 20:679-686 (Pubitemid 47340628)
44. Krahling H, Mally S, Eble JA, Noel J et al (2009) The glycocalyx maintains a cell surface pH nanoenvironment crucial for integrinmediated migration of human melanoma cells. Pflugers Arch 458:1069-1083
45. Reber F, Gersch U, Funk RW (2003) Blockers of carbonic anhydrase can cause increase of retinal capillary diameter, decrease of extracellular and increase of intracellular pH in rat retinal organ culture. Graefes Arch Clin Exp Ophthalmol 241:140-148 (Pubitemid 36747802)
46. Svastova E, Hulikova A, Rafajova M, Zat'ovicova M et al (2004) Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. FEBS Lett 577:439-445 (Pubitemid 39535327)
47. 2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J Physiol 581: 1235-1246 (Pubitemid 46887990)
48. 2+ exchange. Biochim Biophys Acta 1797: 1627-1637
49. + exchanger, NHE1: structure, regulation, and cellular actions. Annu Rev Pharmacol Toxicol 42:527-552 (Pubitemid 34160535)
50. + exchangers by measurement of reverse mode reaction. J Biol Chem 278:43580-43585 (Pubitemid 37345983)
51. Olbe L, Carlsson E, Lindberg P (2003) A proton-pump inhibitor expedition: the case histories of omeprazole and esomeprazole. Nat Rev Drug Discov 2:132-139 (Pubitemid 37361645)
52. Miyagi T, Wada T, Yamaguchi K, Hata K et al (2008) Plasma membrane-associated sialidase as a crucial regulator of transmembrane signalling. J Biochem 144:279-285
53. Preti A, Fiorilli A, Lombardo A, Caimi L et al (1980) Occurrence of sialyltransferase activity in the synaptosomal membranes prepared from calf brain cortex. J Neurochem 35:281-296 (Pubitemid 10034400)
54. Crespo PM, Demichelis VT, Daniotti JL (2010) Neobiosynthesis of glycosphingolipids by plasma membrane-associated glycosyltransferases. J Biol Chem 285:29179-29190
55. Alessenko AV (2000) The role of sphingomyelin cycle metabolites in transduction of signals of cell proliferation, differentiation and death. Membr Cell Biol 13:303-320 (Pubitemid 30184417)
56. van Blitterswijk WJ, van der Luit AH, Veldman RJ, Verheij M et al (2003) Ceramide: second messenger or modulator of membrane structure and dynamics? Biochem J 369:199-211 (Pubitemid 36174190)
57. Miyagi T, Wada T, Iwamatsu A, Hata K et al (1999) Molecular cloning and characterization of a plasma membrane-associated sialidase specific for gangliosides. J Biol Chem 274:5004-5011
58. Reddy A, Caler EV, Andrews NW (2001) Plasma membrane repair is mediated by Ca(2+)-regulated exocytosis of lysosomes. Cell 106:157-169 (Pubitemid 32772627)
59. Stuwe L, Muller M, Fabian A, Waning J et al (2007) pH dependence of melanoma cell migration: protons extruded by NHE1 dominate protons of the bulk solution. J Physiol 585:351-360 (Pubitemid 350193911)
60. + exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. J Biol Chem 279: 26991-27007 (Pubitemid 38812535)
61. Kalka D, von Reitzenstein C, Kopitz J, Cantz M (2001) The plasma membrane ganglioside sialidase cofractionates with markers of lipid rafts. Biochem Biophys Res Commun 283: 989-993 (Pubitemid 32924678)
62. Wang Y, Yamaguchi K, Wada T, Hata K et al (2002) A close association of the ganglioside-specific sialidase Neu3 with caveolin in membrane microdomains. J Biol Chem 277:26252-26259 (Pubitemid 34967114)
63. + exchanger 1 expression protects Ca2+-regulated adenylyl cyclases from changes in intracellular pH. J Biol Chem 280:30864-30872 (Pubitemid 41291817)
64. Prinetti A, Loberto N, Chigorno V, Sonnino S (2009) Glycosphingolipid behaviour in complex membranes. Biochim Biophys Acta 1788:184-193