Transgenic mouse models of hormonal mammary carcinogenesis: Advantages and limitations

Journal of Steroid Biochemistry and Molecular Biology

Volumn 131, Issue 3-5, 2012, Pages 76-82

  Kirma, Nameer B ^a   Tekmal, Rajeshwar R ^a  

^a University of Texas Health Science Center   (United States)

Author keywords

Breast cancer; Hormone mediated cancer models; Hormones and cancer; Transgenic models

Indexed keywords

4 CHLOROPHENYLACETIC ACID; ANDROGEN RECEPTOR; AROMATASE; AROMATASE INHIBITOR; BRCA1 PROTEIN; CYCLIN D1; CYCLIN E; CYTOCHROME P450 1B1; DIOXIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; EVEROLIMUS; FATTY ACID; HISTONE; LETROZOLE; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; NATURAL PRODUCT; PHOSPHATIDYLINOSITOL 3 KINASE; PROGESTERONE RECEPTOR; PROLINE GLUTAMIC ACID LEUCINE RICH PROTEIN; PROTEIN P53; SELECTIVE ESTROGEN RECEPTOR MODULATOR; SOMATOMEDIN C; STAT3 PROTEIN; STEROID RECEPTOR COACTIVATOR 3; TAMOXIFEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; BREAST CANCER; BREAST CARCINOGENESIS; BREAST HYPERPLASIA; CANCER CELL CULTURE; CANCER MODEL; CANCER PREVENTION; CELL CYCLE; DRUG TARGETING; ESTROGEN ACTIVITY; GENE EXPRESSION; GENOTOXICITY; HORMONE METABOLISM; KNOCKOUT MOUSE; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; ONCOGENE; PRECANCER; PROMOTER REGION; RED WINE; REVIEW; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, NEOPLASM; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NEOPLASM PROTEINS; NUCLEAR RECEPTOR COACTIVATORS; TRANSLATIONAL MEDICAL RESEARCH;

MUS; MUS MUSCULUS;

EID: 84862846155     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2011.11.005     Document Type: Review

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