Colony stimulating factor-1 receptor as a target for small molecule inhibitors

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 5, 2010, Pages 1789-1797

  Mashkani, Baratali ^a   Griffith, Renate ^b   Ashman, Leonie K ^a,c  

^a UNIVERSITY OF NEWCASTLE   (Australia)

^b UNIVERSITY OF NEWCASTLE   (Australia)

^c HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

Author keywords

Binding mode; Drug design; Flexible docking; Kinase domain conformation; Kinase inhibition

Indexed keywords

COLONY STIMULATING FACTOR 1; CSF 1; DASATINIB; IMATINIB; LESTAURTINIB; MIDOSTAURIN; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 1;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG POTENTIATION; DRUG SELECTIVITY; DRUG STRUCTURE; ENZYME CONFORMATION; NONHUMAN; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; RECEPTOR BINDING;

BINDING SITES; CARBAZOLES; COMPUTER SIMULATION; DRUG DESIGN; HUMANS; HYDROGEN BONDING; INDOLES; PIPERAZINES; PROTEIN KINASE INHIBITORS; PYRIMIDINES; PYRROLES; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; STAUROSPORINE; THIAZOLES;

EID: 77249164470     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.01.056     Document Type: Article

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