-
1
-
-
0026530097
-
Human gene therapy
-
W.F. Anderson Human gene therapy Science 256 1992 808 813
-
(1992)
Science
, vol.256
, pp. 808-813
-
-
Anderson, W.F.1
-
2
-
-
0029160083
-
A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: Polyethylenimine
-
O. Boussif, F. Lezoualc'h, M.A. Zanta, M.D. Mergny, D. Scherman, B. Demeneix, and J.P. Behr A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine Proc. Natl. Acad. Sci. U.S.A. 92 1995 7297
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 7297
-
-
Boussif, O.1
Lezoualc'H, F.2
Zanta, M.A.3
Mergny, M.D.4
Scherman, D.5
Demeneix, B.6
Behr, J.P.7
-
3
-
-
0036953575
-
Lentiviruses in gene therapy clinical research
-
J.B. Connolly Lentiviruses in gene therapy clinical research Gene Ther. 9 2002 1730 1734
-
(2002)
Gene Ther.
, vol.9
, pp. 1730-1734
-
-
Connolly, J.B.1
-
4
-
-
0038004448
-
A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: Effect of molecular weight on transfection efficiency and cytotoxicity
-
DOI 10.1023/A:1014861900478
-
D. Fischer, T. Bieber, Y. Li, H.P. Elsasser, and T. Kissel A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine. Effect of molecular weight on transfection efficiency and cytotoxicity Pharmaceut. Res. 16 1999 1273 1279 (Pubitemid 29393618)
-
(1999)
Pharmaceutical Research
, vol.16
, Issue.8
, pp. 1273-1279
-
-
Fischer, D.1
Bieber, T.2
Li, Y.3
Elsasser, H.-P.4
Kissel, T.5
-
5
-
-
15944400651
-
Towards safe, non-viral therapeutic gene expression in humans
-
DOI 10.1038/nrg1577
-
D.J. Glover, H.J. Lipps, and D.A. Jans Towards safe, non-viral therapeutic gene expression in humans Nat. Rev. Genet. 6 2005 299 310 (Pubitemid 40469049)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.4
, pp. 299-310
-
-
Glover, D.J.1
Lipps, H.J.2
Jans, D.A.3
-
6
-
-
0035214028
-
Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine
-
DOI 10.1021/bc0100455
-
M.A. Gosselin, W. Guo, and R.J. Lee Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine Bioconjug. Chem. 12 2001 989 994 (Pubitemid 33136869)
-
(2001)
Bioconjugate Chemistry
, vol.12
, Issue.6
, pp. 989-994
-
-
Gosselin, M.A.1
Guo, W.2
Lee, R.J.3
-
7
-
-
0035816168
-
PEG drugs: An overview
-
DOI 10.1016/S0168-3659(01)00331-5, PII S0168365901003315
-
R.B. Greenwald PEG drugs: an overview J. Control. Release 74 2001 159 171 (Pubitemid 32727618)
-
(2001)
Journal of Controlled Release
, vol.74
, Issue.1-3
, pp. 159-171
-
-
Greenwald, R.B.1
-
8
-
-
84862817136
-
-
WO Patent WO/2010/083,104
-
Joshi, H., Vangapandu, S., Anelja, R., 2010. Conjugates of noscapine and folic acid and their use in treating cancer. WO Patent WO/2010/083,104.
-
(2010)
Conjugates of Noscapine and Folic Acid and Their Use in Treating Cancer
-
-
Joshi, H.1
Vangapandu, S.2
Anelja, R.3
-
9
-
-
0035286969
-
Polyethylenimine-mediated gene delivery: A mechanistic study
-
DOI 10.1002/jgm.173
-
A. Kichler, C. Leborgne, E. Coeytaux, and O. Danos Polyethylenimine- mediated gene delivery: a mechanistic study J. Gene Med. 3 2001 135 144 (Pubitemid 33685440)
-
(2001)
Journal of Gene Medicine
, vol.3
, Issue.2
, pp. 135-144
-
-
Kichler, A.1
Leborgne, C.2
Coeytaux, E.3
Danos, O.4
-
10
-
-
0037437033
-
Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: Comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine
-
DOI 10.1016/S0168-3659(03)00076-2
-
K. Kunath, A. von Harpe, D. Fischer, H. Petersen, U. Bickel, K. Voigt, and T. Kissel Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine J. Control. Release 89 2003 113 125 (Pubitemid 36412116)
-
(2003)
Journal of Controlled Release
, vol.89
, Issue.1
, pp. 113-125
-
-
Kunath, K.1
Von Harpe, A.2
Fischer, D.3
Petersen, H.4
Bickel, U.5
Voigt, K.6
Kissel, T.7
-
11
-
-
34548634706
-
An electrochemical method to detect folate receptor positive tumor cells
-
DOI 10.1016/j.elecom.2007.07.032, PII S1388248107003189
-
L. Liu, X. Zhu, D. Zhang, J. Huang, and G. Li An electrochemical method to detect folate receptor positive tumor cells Electrochem. Commun. 9 2007 2547 2550 (Pubitemid 47405288)
-
(2007)
Electrochemistry Communications
, vol.9
, Issue.10
, pp. 2547-2550
-
-
Liu, L.1
Zhu, X.2
Zhang, D.3
Huang, J.4
Li, G.5
-
12
-
-
2942623508
-
In vitro and in vivo delivery of intact BAC DNA - Comparison of different methods
-
DOI 10.1002/jgm.481
-
C. Magin Lachmann, G. Kotzamanis, L. D'Aiuto, H. Cooke, C. Huxley, and E. Wagner In vitro and in vivo delivery of intact BAC DNA - comparison of different methods J. Gene Med. 6 2004 195 209 (Pubitemid 40228038)
-
(2004)
Journal of Gene Medicine
, vol.6
, Issue.2
, pp. 195-209
-
-
Magin-Lachmann, C.1
Kotzamanis, G.2
D'Aiuto, L.3
Cooke, H.4
Huxley, C.5
Wagner, E.6
-
13
-
-
0033579358
-
Clinical trials: Gene therapy death prompts review of adenovirus vector
-
E. Marshall Clinical trials: gene therapy death prompts review of adenovirus vector Science 286 1999 2244
-
(1999)
Science
, vol.286
, pp. 2244
-
-
Marshall, E.1
-
14
-
-
19744372388
-
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
-
J.G. Med Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis J. Gene Med. 7 2005 657 663
-
(2005)
J. Gene Med.
, vol.7
, pp. 657-663
-
-
Med, J.G.1
-
15
-
-
0029836780
-
Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy
-
N. Mittereder, K.L. March, and B.C. Trapnell Evaluation of the concentration and bioactivity of adenovirus vectors for gene therapy J. Virol. 70 1996 7498 7509 (Pubitemid 26339054)
-
(1996)
Journal of Virology
, vol.70
, Issue.11
, pp. 7498-7509
-
-
Mittereder, N.1
March, K.L.2
Trapnell, B.C.3
-
16
-
-
19444372923
-
A two-stage poly(ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy
-
DOI 10.1016/j.ymthe.2005.02.010, PII S1525001605000808
-
S.M. Moghimi, P. Symonds, J.C. Murray, A.C. Hunter, G. Debska, and A. Szewczyk A two-stage poly (ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy Mol. Ther. 11 2005 990 995 (Pubitemid 40724119)
-
(2005)
Molecular Therapy
, vol.11
, Issue.6
, pp. 990-995
-
-
Moghimi, S.M.1
Symonds, P.2
Murray, J.C.3
Hunter, A.C.4
Debska, G.5
Szewczyk, A.6
-
17
-
-
0027595949
-
The basic science of gene therapy
-
R.C. Mulligan The basic science of gene therapy Science 260 1993 926 932
-
(1993)
Science
, vol.260
, pp. 926-932
-
-
Mulligan, R.C.1
-
18
-
-
23944464631
-
Recent advances in rational gene transfer vector design based on poly(ethylene imine) and its derivatives
-
DOI 10.1002/jgm.773
-
M. Neu, D. Fischer, and T. Kissel Recent advances in rational gene transfer vector design based on poly (ethylene imine) and its derivatives J. Gene Med. 7 2005 992 1009 (Pubitemid 41195062)
-
(2005)
Journal of Gene Medicine
, vol.7
, Issue.8
, pp. 992-1009
-
-
Neu, M.1
Fischer, D.2
Kissel, T.3
-
19
-
-
0032938324
-
PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
-
DOI 10.1038/sj.gt.3300900
-
M. Ogris, S. Brunner, S. Schüller, R. Kircheis, and E. Wagner PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery Gene Ther. 4 1999 595 605 (Pubitemid 29192668)
-
(1999)
Gene Therapy
, vol.6
, Issue.4
, pp. 595-605
-
-
Ogris, M.1
Brunner, S.2
Schuller, S.3
Kircheis, R.4
Wagner, E.5
-
20
-
-
33745460260
-
Current status of polymeric gene delivery systems
-
DOI 10.1016/j.addr.2006.03.007, PII S0169409X06000500
-
T.G. Park, J.H. Jeong, and S.W. Kim Current status of polymeric gene delivery systems Adv. Drug Deliver. Rev. 58 2006 467 486 (Pubitemid 43949425)
-
(2006)
Advanced Drug Delivery Reviews
, vol.58
, Issue.4
, pp. 467-486
-
-
Park, T.G.1
Jeong, J.H.2
Kim, S.W.3
-
21
-
-
0032954377
-
Liposomal lipid and plasmid DNA delivery to B16/BL6 tumors after intraperitoneal administration of cationic liposome DNA aggregates
-
D.L. Reimer, S. Kong, M. Monck, J. Wyles, P. Tam, E.K. Wasan, and M.B. Bally Liposomal lipid and plasmid DNA delivery to B16/BL6 tumors after intraperitoneal administration of cationic liposome DNA aggregates J. Pharmacol. Exp. Therap. 289 1999 807 815 (Pubitemid 29191235)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.289
, Issue.2
, pp. 807-815
-
-
Reimer, D.L.1
Kong, S.2
Monck, M.3
Wyles, J.4
Tam, P.5
Wasan, E.K.6
Bally, M.B.7
-
22
-
-
0034328925
-
Gene therapy: Trials and tribulations
-
N. Somia, and I.M. Verma Gene therapy: trials and tribulations Nat. Rev. Genetics 1 2000 91 99
-
(2000)
Nat. Rev. Genetics
, vol.1
, pp. 91-99
-
-
Somia, N.1
Verma, I.M.2
-
23
-
-
0041808932
-
Gene therapy progress and prospects: Adenoviral vectors
-
J.A. StGeorge Gene therapy progress and prospects: adenoviral vectors Gene Ther. 10 2003 1135 1141
-
(2003)
Gene Ther.
, vol.10
, pp. 1135-1141
-
-
Stgeorge, J.A.1
-
24
-
-
0642286447
-
Effect of polyethylene glycol on gene delivery of polyethylenimine
-
S.J. Sung, S.H. Min, K.Y. Cho, S. Lee, Y.J. Min, Y.I. Yeom, and J.K. Park Effect of polyethylene glycol on gene delivery of polyethylenimine Biol. Pharmaceut. Bull. 26 2003 492 500 (Pubitemid 39663595)
-
(2003)
Biological and Pharmaceutical Bulletin
, vol.26
, Issue.4
, pp. 492-500
-
-
Sung, S.-J.1
Min, S.H.2
Cho, K.Y.3
Lee, S.4
Min, Y.-J.5
Yeom, Y.I.6
Park, J.-K.7
-
25
-
-
0037409735
-
Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: Effects of PEGylation extent
-
DOI 10.1016/S0142-9612(03)00029-2
-
G.P. Tang, J.M. Zeng, S.J. Gao, Y.X. Ma, L. Shi, Y. Li, H.P. Too, and S. Wang Polyethylene glycol modified polyethylenimine for improved CNS gene transfer: effects of PEGylation extent Biomaterials 24 2003 2351 2362 (Pubitemid 36434055)
-
(2003)
Biomaterials
, vol.24
, Issue.13
, pp. 2351-2362
-
-
Tang, G.P.1
Zeng, J.M.2
Gao, S.J.3
Ma, Y.X.4
Shi, L.5
Li, Y.6
Too, H.-P.7
Wang, S.8
-
26
-
-
0038745599
-
Progress and problems with the use of viral vectors for gene therapy
-
DOI 10.1038/nrg1066
-
C.E. Thomas, A. Ehrhardt, and M.A. Kay Progress and problems with the use of viral vectors for gene therapy Nat. Rev. Genetics 4 2003 346 358 (Pubitemid 36538359)
-
(2003)
Nature Reviews Genetics
, vol.4
, Issue.5
, pp. 346-358
-
-
Thomas, C.E.1
Ehrhardt, A.2
Kay, M.A.3
-
27
-
-
17644401347
-
Cross-linked small polyethylenimines: While still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo
-
DOI 10.1007/s11095-004-1874-y
-
M. Thomas, Q. Ge, J.J. Lu, J. Chen, and A. Klibanov Cross-linked small polyethylenimines: while still nontoxic, deliver DNA efficiently to mammalian cells in vitro and in vivo Pharmaceut. Res. 22 2005 373 380 (Pubitemid 40558495)
-
(2005)
Pharmaceutical Research
, vol.22
, Issue.3
, pp. 373-380
-
-
Thomas, M.1
Ge, Q.2
Lu, J.J.3
Chen, J.4
Klibanov, A.M.5
-
28
-
-
0038574350
-
Non-viral gene therapy: Polycation-mediated DNA delivery
-
DOI 10.1007/s00253-003-1321-8
-
M. Thomas, and A.M. Klibanov Non-viral gene therapy: polycation-mediated DNA delivery Appl. Microbiol. Biotechnol. 62 2003 27 34 (Pubitemid 36836536)
-
(2003)
Applied Microbiology and Biotechnology
, vol.62
, Issue.1
, pp. 27-34
-
-
Thomas, M.1
Klibanov, A.M.2
-
29
-
-
0030805317
-
Relation between transfection efficiency and cytotoxicity of poly(2-dimethylamino)ethyl methacrylate)/plasmid complexes
-
DOI 10.1016/S0168-3659(97)00059-X, PII S016836599700059X
-
P. van de Wetering, J.Y. Cherng, H. Talsma, and W.E. Hennink Relation between transfection efficiency and cytotoxicity of poly (2-(dimethylamino) ethyl methacrylate)/plasmid complexes J. Control. Release 49 1997 59 69 (Pubitemid 27417901)
-
(1997)
Journal of Controlled Release
, vol.49
, Issue.1
, pp. 59-69
-
-
Van De Wetering, P.1
Cherng, J.-Y.2
Talsma, H.3
Hennink, W.E.4
-
30
-
-
0030928619
-
Gene therapy-promises, problems and prospects
-
I.M. Verma, and N. Somia Gene therapy-promises, problems and prospects Nature 389 1997 239 242
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
31
-
-
33646152761
-
A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes
-
S. Werth, B. Urban-Klein, L. Dai, S. Höbel, M. Grzelinski, U. Bakowsky, F. Czubayko, and A. Aigner A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection efficiency of DNA and siRNA in fresh or lyophilized complexes J. Control. Release 112 2006 257 270
-
(2006)
J. Control. Release
, vol.112
, pp. 257-270
-
-
Werth, S.1
Urban-Klein, B.2
Dai, L.3
Höbel, S.4
Grzelinski, M.5
Bakowsky, U.6
Czubayko, F.7
Aigner, A.8
-
32
-
-
0035408714
-
Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo
-
DOI 10.1002/jgm.187
-
L. Wightman, R. Kircheis, V. Rössler, S. Carotta, R. Ruzicka, M. Kursa, and E. Wagner Different behavior of branched and linear polyethylenimine for gene delivery in vitro and in vivo J. Gene Med. 3 2001 362 372 (Pubitemid 33691776)
-
(2001)
Journal of Gene Medicine
, vol.3
, Issue.4
, pp. 362-372
-
-
Wightman, L.1
Kircheis, R.2
Rossler, V.3
Garotta, S.4
Ruzicka, R.5
Kursa, M.6
Wagner, E.7
-
33
-
-
34447508073
-
Screening of the Metastasis-Associated Genes by Gene Chip in High Metastatic Human Ovarian Cancer Cell Lines
-
DOI 10.1016/S1673-8527(07)60066-6, PII S1673852707600666
-
S. Xu, H. Mou, L. Gu, D. Su, C. Zhu, and X. Liu Screening of the metastasis-associated genes by gene chip in high metastatic human ovarian cancer cell lines J. Genet. Genomics 34 2007 581 590 (Pubitemid 47069978)
-
(2007)
Journal of Genetics and Genomics
, vol.34
, Issue.7
, pp. 581-590
-
-
Xu, S.1
Mou, H.2
Gu, L.3
Su, D.4
Zhu, C.5
Liu, X.6
-
34
-
-
8544219695
-
Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate
-
DOI 10.1016/j.jconrel.2004.08.017, PII S0168365904003931
-
H.S. Yoo, and T.G. Park Folate-receptor-targeted delivery of doxorubicin nano-aggregates stabilized by doxorubicin-PEG-folate conjugate J. Control. Release 100 2004 247 256 (Pubitemid 39491276)
-
(2004)
Journal of Controlled Release
, vol.100
, Issue.2
, pp. 247-256
-
-
Yoo, H.S.1
Park, T.G.2
-
35
-
-
0142229694
-
Direct real-time molecular scale visualisation of the degradation of condensed DNA complexes exposed to DNase i
-
H.G. Abdelhady, S. Allen, M.C. Davies, C.J. Roberts, S.J.B. Tendler, and P.M. Williams Direct real-time molecular scale visualisation of the degradation of condensed DNA complexes exposed to DNase I Nucleic Acids Res. 31 2003 4001
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 4001
-
-
Abdelhady, H.G.1
Allen, S.2
Davies, M.C.3
Roberts, C.J.4
Tendler, S.J.B.5
Williams, P.M.6
-
36
-
-
0032801779
-
Biological barriers to cellular delivery of lipid-based DNA carriers
-
DOI 10.1016/S0169-409X(99)00034-4, PII S0169409X99000344
-
M.B. Bally, P. Harvie, F.M.P. Wong, S. Kong, E.K. Wasan, and D.L. Reimer Biological barriers to cellular delivery of lipid-based DNA carriers Adv. Drug Deliver. Rev. 38 1999 291 315 (Pubitemid 29376579)
-
(1999)
Advanced Drug Delivery Reviews
, vol.38
, Issue.3
, pp. 291-315
-
-
Bally, M.B.1
Harvie, P.2
Wong, F.M.P.3
Kong, S.4
Wasan, E.K.5
Reimer, D.L.6
-
37
-
-
0030852003
-
Cationic lipid-based gene delivery systems: Pharmaceutical perspectives
-
DOI 10.1023/A:1012187414126
-
R.I. Mahato, A. Rolland, and E. Tomlinson Cationic lipid-based gene delivery systems: pharmaceutical perspectives Pharmaceut. Res. 14 1997 853 859 (Pubitemid 27326978)
-
(1997)
Pharmaceutical Research
, vol.14
, Issue.7
, pp. 853-859
-
-
Mahato, R.I.1
Rolland, A.2
Tomlinson, E.3
|