Liposomal lipid and plasmid DNA delivery to B16/BL6 tumors after intraperitoneal administration of cationic liposome DNA aggregates

Journal of Pharmacology and Experimental Therapeutics

Volumn 289, Issue 2, 1999, Pages 807-815

  Reimer, Dorothy L ^a   Kong, Spencer ^a   Monck, Myrna ^b   Wyles, Jessica ^c   Tam, Pat ^b   Wasan, Ellen K ^a   Bally, Marcel B ^a  

^a BRITISH COLUMBIA CANCER AGENCY   (Canada)

^b Inex Pharmaceuticals   (Canada)

^c British Columbia Cancer Agency ^*

Author keywords

[No Author keywords available]

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; DIOLEOYLDIMETHYLAMMONIUM CHLORIDE; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; LIPOSOME; PHOSPHOLIPID; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; CONFERENCE PAPER; DOT HYBRIDIZATION; FEMALE; GENE EXPRESSION; GENE TARGETING; GENE TRANSFER; INTRAPERITONEAL DRUG ADMINISTRATION; MELANOMA B16; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOUTHERN BLOTTING;

ANIMALS; BLOTTING, SOUTHERN; CHLORAMPHENICOL O-ACETYLTRANSFERASE; ESCHERICHIA COLI; FEMALE; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; INJECTIONS, INTRAPERITONEAL; LIPIDS; LIPOSOMES; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NEOPLASM TRANSPLANTATION; PHOSPHATIDYLETHANOLAMINES; PLASMIDS; QUATERNARY AMMONIUM COMPOUNDS; TISSUE DISTRIBUTION;

EID: 0032954377     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (35)

1. Alton EWFW, Middleton PG, Caplen SN, Smith DM, Steel FM, Munkonge PK, Jeffrey DM, Geddes SL, Hart R, Williamson KI, Fasold AD, Miller P, Dickinson DJ, Stevenson BJ, Mclachlan G, Dorin JR and Porteous DJ (1993) Non-invasive liposome-mediated gene delivery can correct the ion transport defect in cystic fibrosis mutant mice. Nat Genet 5:135-142
2. Bally MB, Lim H, Cellis PR and Mayen LD (1998) Controlling the drug delivery attributes of lipid-based drug formulations. J Liposome Res 8:299-335.
3. Brigham KL, Meyrick B, Christman B, Conary JT, King G and Berry LC Jr (1989) In vivo transfection of murine lungs with a functioning prokaryotic gene using a liposome vehicle. Am J Med Sci 298:278-281.
4. Caplen NJ, Alton EWFW, Middleton JR, Dorin BJ, Stevenson X, Gao SR, Durham PK, Jeffrey ME, Hodson C, Coutelle C, Huang L, Porteous DJ, Williamson R and Geddes DM (1995) Liposome-mediated CFTR gene transfer to the nasal epithelium of patients with cystic fibrosis. Nat Med 1:39-46.
5. Chang YJ, Xia W, Shao R, Sorgi F, Hortobagyi GN, Huang L and Hung MC (1997) The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer. Oncogene 14:39-46.
6. Egilmez NK, Cuenca R, Yokota SJ, Sorgi F and Bankert RB (1996) In vivo cytokine gene therapy of human tumor xenografts in SCID mice by liposome-mediated DNA delivery. Gene Ther 8:607-614.
7. Feigner PL, Barenholz Y, Behr JP, Cheng SH, Cullis P, Huang L, Jessee JA, Seymour L, Szoka F, Thierry AR, Wagner E and Wu G (1997) Nomenclature for synthetic gene delivery systems. Hum Gene Ther 8:511-512.
8. Harvie P, Wong FMP and Bally MB (1998) Characterization of lipid DNA interactions. I. Destabilisation of bound lipids and DNA dissociation. Biophys J 75:1040-1051.
9. Hope MJ, Bally MB, Webb M and Cullis PR (1985) Production of large unilamellar vesicles by a rapid extrusion procedure: Characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochim Biophys Acta 812:55-65.
10. Hyde SC, Gill DR, Higgins CF, Trezise AE, Macvinish LJ, Cuthbert AW, Ratcliff R, Evans MJ and Colledge WH (1993) Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature (Lond) 362:250-255.
11. Jiao S, Ascadi G, Jani A, Felgner P and Wolff JA (1992) Persistence of plasmid DNA and expression in rat brain cells in vivo. Exp Neurobiol 115:400-413.
12. Meyer KB, Thompson MM, Levy MY, Barron LG and Szoka FC Jr (1995) Intratracheal gene delivery to the mouse airway: Characterization of plasmid DNA expression and pharmacokinetics. Gene Ther 2:450-460.
13. Nabel GJ, Nabel EG, Yang ZY, Fox BA, Plautz GE, Gao X, Huang L, Shu S, Gordon D and Chang AE (1993) Direct gene transfer with DNA-liposome complexes in melanoma: Expression, biological activity and lack of toxicity in humans. Proc Natl Acad Sci USA 90:11301-11311.
14. Nabel EG, Plautz G, Boyce FM, Stanley JC and Nabel GJ (1989) Recombinant gene expression in vivo within endothelial cells of the arterial wall. Science (Wash) 244:1342-1343.
15. Nabel EG, Plautz G and Nabel GJ (1990) Site-specific gene expression in vivo by direct gene transfer into the arterial wall. Science (Wash)249:1285-1288.
16. Nabel EG, Plautz G and Nabel GJ (1992) Transduction of a foreign histocompatibility gene into the arterial wall induces vasculitis. Proc Natl Acad Sci USA 89:5157-5161.
17. Ono T, Fujino Y, Tsuchiya T and Tsuda M (1990) Plasmid DNAs directly injected into mouse brain with lipofectin can be incorporated and expressed by brain cells. Neurosci Lett 117:259-263.
18. Parker SE, Khatibi S, Margalith M, Anderson D, Yankauckas M, Gromkowski SH, Latimer T, Lew D, Marquet M, Manthorpe M, Hobart PL, Hersh E, Stopeck AT and Norman J (1996) Plasmid DNA gene therapy: Studies with the human interleukin-2 gene in tumor cells in vitro and in the murine B16 melanoma model in vivo. Cancer Gene Ther 3:175-185.
19. Philip R, Liggitt D, Philip M, Dazin P and Debs R (1993) In vivo gene delivery. Efficient transfection of T lymphocytes in adult mice. J Biol Chem 268:16087-16090.
20. Plautz GE, Yang ZY, Wu BY, Gao X, Huang L and Nabel GJ (1993) Immunotherapy of malignancy by in vivo gene transfer in tumors. Proc Natl Acad Sci USA 90:4645-4649.
21. Reimer DL, Kong S and Bally MB (1997) Analysis of cationic liposome-mediated interactions of plasmid DNA with murine and human melanoma cells in vitro. J Biol Chem 272:19480-19487.
22. Rubin J, Galanis E, Pitot HC, Richardson RL, Burch PA, Charboneau JW, Reading CC, Lewis BD, Stahl S, Akporiaye ET and Harris DT (1997) Phase I study of immunotherapy of hepatic metastases of colorectal carcinoma by direct gene transfer of an allogenic histocompatibility antigen, HLA-B7. Gene Ther 4:419-425.
23. Sambrook J, Fritsch EF and Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd ed., Cold Spring Harbor Press, Cold Spring Harbor, New York.
24. Scherphof GL, Kuipers F, Derksen JTP, Spanjer HH and Vonk EJ (1987) Liposomes in vivo: Conversion of liposomal cholesterol to bile salts. Biochem Soc Trans 15:625-628.
25. Silver HKB, Klasa BJ and Bally MB (1996) Genetic allogenization of malignant melanoma. Transfus Sci 17:169-174.
26. Smith JG, Walzem RL and German JB (1993) Liposomes as agents of gene transfer. Biochim Biophys Acta 1154:327-340.
27. Stephan DJ, Yang ZY, San H, Simari RD, Wheeler CJ, Gordon D, Nabel GJ and Nabel EG (1996) A new cationic liposome DNA complex enhances the efficiency of arterial gene transfer in vivo. Hum Gene Ther 7:1803-1812.
28. Stopeck AT, Hersh EM, Akporiaye ET, Harris DT, Grogan T, Unger E, Warneke J, Schluter SF and Stahl S (1997) Phase I study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in patients with metastatic melanoma. J Clin Oncol 15:341-349.
29. Stribling R, Brunette E, Liggitt D, Gaensler K and Debs R (1992) Aerosol gene delivery in vivo. Proc Natl Acad Sci USA 89:11277-11281.
30. Szoka FC Jr, Xu Y and Zelphati O (1996) How are nucleic acids released in cells from cationic lipid-nucleic acid complexes? J Liposome Res 6:567-587.
31. Thierry AR, Lunardi-Iskandar Y, Bryant JL, Rabinovich P, Gallo RC and Mahan LC (1995) Systemic gene therapy: Biodistribution and long-term expression of a transgene in mice. Proc Natl Acad Sci USA 92:9742-9746.
32. Wheeler CJ, Felgner P, Tsai YJ, Marshall J, Sukhu L, Doh SG, Hartikka J, Nietpuski J, Yang G, Manthorpe M, Nichols M, Plewe M, Liang X, Norman J, Smith A and Cheng SH (1996) A novel cationic lipid greatly enhances plasmid DNA delivery and expression in mouse lung. Proc Natl Acad Sci USA 93:11454-11459.
33. Yang J-P and Huang L (1996) Direct gene transfer to mouse melanoma by intratumor injection of free DNA. Gene Ther 3:542-548.
34. Zabner J, Fasbender AJ, Moninger T, Poellinger KA and Welsh MJ (1995) Cellular and molecular barriers to gene transfer by a cationic lipid. J Biol Chem 270:18997-19007.
35. Zhu N, Liggitt D, Liu Y and Debs R (1993) Systemic gene expression after intravenous DNA delivery into adult mice. Science (Wash)261:209-211.