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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 8, 2012, Pages 2997-3000

Development of clickable active site-directed photoaffinity probes for γ-secretase

(9) Crump, Christina J a,b Am Ende, Christopher W c Eric Ballard, T c Pozdnyakov, Nikolay c Pettersson, Martin c Chau, De Ming a,b Bales, Kelly R c Li, Yue Ming a,b Johnson, Douglas S c

a MEMORIAL SLOAN KETTERING CANCER CENTER (United States)

b Weill Cornell Medical Center (United States)

c PFIZER INC (United States)

Author keywords

Secretase; Alzheimer's disease; Click chemistry; Clickable photoprobe; Photoaffinity labeling

Indexed keywords

ALKYNE; ASPARTIC PROTEINASE; AZIDE; BENZOPHENONE; BIOTIN; GAMMA SECRETASE; GAMMA SECRETASE INHIBITOR; L 505; L 646; PEPTIDASE; PRESENILIN 1; SIGNAL PEPTIDE PEPTIDASE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CLICK CHEMISTRY; COMPLEX FORMATION; CONJUGATION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVE SITE; FLUORESCENCE; GEL; HUMAN; HUMAN CELL; MOLECULAR PROBE; NONHUMAN; PHOTOAFFINITY LABELING; VALIDATION PROCESS; WESTERN BLOTTING;

ALKYNES; AMYLOID PRECURSOR PROTEIN SECRETASES; BENZOPHENONES; BLOTTING, WESTERN; CATALYTIC DOMAIN; CLICK CHEMISTRY; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR STRUCTURE; PHOTOAFFINITY LABELS;

EID: 84862817371 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.02.027 Document Type: Article

Times cited : (28)

References (33)

1
- 84857780152
- P.P. Geurink, L.M. Prely, G.A. van der Marel, R. Bischoff, and H.S. Overkleeft Top. Curr. Chem. 324 2012 85
- (2012) Top. Curr. Chem. , vol.324 , pp. 85
- Geurink, P.P.¹ Prely, L.M.² Van Der Marel, G.A.³ Bischoff, R.⁴ Overkleeft, H.S.⁵

2
- 77957787895
- K.F. Geoghegan, and D.S. Johnson Annu. Rep. Med. Chem. 45 2010 345
- (2010) Annu. Rep. Med. Chem. , vol.45 , pp. 345
- Geoghegan, K.F.¹ Johnson, D.S.²

3
- 0036861121
- M. Xu, M.T. Lai, Q. Huang, J. DiMuzio-Mower, J.L. Castro, T. Harrison, A. Nadin, J.G. Neduvelil, M.S. Shearman, J.A. Shafer, S.J. Gardell, and Y.M. Li Neurobiol. Aging 23 2002 1023
- (2002) Neurobiol. Aging , vol.23 , pp. 1023
- Xu, M.¹ Lai, M.T.² Huang, Q.³ Dimuzio-Mower, J.⁴ Castro, J.L.⁵ Harrison, T.⁶ Nadin, A.⁷ Neduvelil, J.G.⁸ Shearman, M.S.⁹ Shafer, J.A.¹⁰ Gardell, S.J.¹¹ Li, Y.M.¹²

4
- 82455210683
- C.J. Crump, D.S. Johnson, and Y.M. Li EMBO J. 30 2011 4696
- (2011) EMBO J. , vol.30 , pp. 4696
- Crump, C.J.¹ Johnson, D.S.² Li, Y.M.³

5
- 71849115226
- S. Yokoshima, Y. Abe, N. Watanabe, Y. Kita, T. Kan, T. Iwatsubo, T. Tomita, and T. Fukuyama Bioorg. Med. Chem. Lett. 19 2009 6869
- (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 6869
- Yokoshima, S.¹ Abe, Y.² Watanabe, N.³ Kita, Y.⁴ Kan, T.⁵ Iwatsubo, T.⁶ Tomita, T.⁷ Fukuyama, T.⁸

6
- 34547597126
- H. Fuwa, Y. Takahashi, Y. Konno, N. Watanabe, H. Miyashita, M. Sasaki, H. Natsugari, T. Kan, T. Fukuyama, T. Tomita, and T. Iwatsubo ACS Chem. Biol. 2 2007 408
- (2007) ACS Chem. Biol. , vol.2 , pp. 408
- Fuwa, H.¹ Takahashi, Y.² Konno, Y.³ Watanabe, N.⁴ Miyashita, H.⁵ Sasaki, M.⁶ Natsugari, H.⁷ Kan, T.⁸ Fukuyama, T.⁹ Tomita, T.¹⁰ Iwatsubo, T.¹¹

7
- 0038607066
- A.Y. Kornilova, C. Das, and M.S. Wolfe J. Biol. Chem. 278 2003 16470
- (2003) J. Biol. Chem. , vol.278 , pp. 16470
- Kornilova, A.Y.¹ Das, C.² Wolfe, M.S.³

8
- 0034602419
- D. Seiffert, J.D. Bradley, C.M. Rominger, D.H. Rominger, F. Yang, J.E. Meredith Jr., Q. Wang, A.H. Roach, L.A. Thompson, S.M. Spitz, J.N. Higaki, S.R. Prakash, A.P. Combs, R.A. Copeland, S.P. Arneric, P.R. Hartig, D.W. Robertson, B. Cordell, A.M. Stern, R.E. Olson, and R. Zaczek J. Biol. Chem. 275 2000 34086
- (2000) J. Biol. Chem. , vol.275 , pp. 34086
- Seiffert, D.¹ Bradley, J.D.² Rominger, C.M.³ Rominger, D.H.⁴ Yang, F.⁵ Meredith, Jr.J.E.⁶ Wang, Q.⁷ Roach, A.H.⁸ Thompson, L.A.⁹ Spitz, S.M.¹⁰ Higaki, J.N.¹¹ Prakash, S.R.¹² Combs, A.P.¹³ Copeland, R.A.¹⁴ Arneric, S.P.¹⁵ Hartig, P.R.¹⁶ Robertson, D.W.¹⁷ Cordell, B.¹⁸ Stern, A.M.¹⁹ Olson, R.E.²⁰ Zaczek, R.²¹ more..

9
- 35348860241
- D.J. Selkoe, and M.S. Wolfe Cell 131 2007 215
- (2007) Cell , vol.131 , pp. 215
- Selkoe, D.J.¹ Wolfe, M.S.²

10
- 61449208917
- For structural studies using cryoelectron microscopy see
- For structural studies using cryoelectron microscopy see, H. Li, M.S. Wolfe, and D.J. Selkoe Structure 17 2009 326
- (2009) Structure , vol.17 , pp. 326
- Li, H.¹ Wolfe, M.S.² Selkoe, D.J.³

11
- 58149094674
- P. Osenkowski, H. Li, W. Ye, D. Li, L. Aeschbach, P.C. Fraering, M.S. Wolfe, and D.J. Selkoe J. Mol. Biol. 385 2009 642
- (2009) J. Mol. Biol. , vol.385 , pp. 642
- Osenkowski, P.¹ Li, H.² Ye, W.³ Li, D.⁴ Aeschbach, L.⁵ Fraering, P.C.⁶ Wolfe, M.S.⁷ Selkoe, D.J.⁸

12
- 79958718948
- F. Renzi, X. Zhang, W.J. Rice, C. Torres-Arancivia, Y. Gomez-Llorente, R. Diaz, K. Ahn, C. Yu, Y.M. Li, S.S. Sisodia, and I. Ubarretxena-Belandia J. Biol. Chem. 286 2011 21440
- (2011) J. Biol. Chem. , vol.286 , pp. 21440
- Renzi, F.¹ Zhang, X.² Rice, W.J.³ Torres-Arancivia, C.⁴ Gomez-Llorente, Y.⁵ Diaz, R.⁶ Ahn, K.⁷ Yu, C.⁸ Li, Y.M.⁹ Sisodia, S.S.¹⁰ Ubarretxena-Belandia, I.¹¹

13
- 0034621824
- Y.M. Li, M. Xu, M.T. Lai, Q. Huang, J.L. Castro, J. DiMuzio-Mower, T. Harrison, C. Lellis, A. Nadin, J.G. Neduvelil, R.B. Register, M.K. Sardana, M.S. Shearman, A.L. Smith, X.P. Shi, K.C. Yin, J.A. Shafer, and S.J. Gardell Nature 405 2000 689
- (2000) Nature , vol.405 , pp. 689
- Li, Y.M.¹ Xu, M.² Lai, M.T.³ Huang, Q.⁴ Castro, J.L.⁵ Dimuzio-Mower, J.⁶ Harrison, T.⁷ Lellis, C.⁸ Nadin, A.⁹ Neduvelil, J.G.¹⁰ Register, R.B.¹¹ Sardana, M.K.¹² Shearman, M.S.¹³ Smith, A.L.¹⁴ Shi, X.P.¹⁵ Yin, K.C.¹⁶ Shafer, J.A.¹⁷ Gardell, S.J.¹⁸

14
- 10344255689
- L. Tarassishin, Y.I. Yin, B. Bassit, and Y.M. Li Proc. Natl. Acad. Sci. U.S.A. 101 2004 17050
- (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 17050
- Tarassishin, L.¹ Yin, Y.I.² Bassit, B.³ Li, Y.M.⁴

15
- 79959636033
- A. Haapasalo, and D.M. Kovacs J. Alzheimers Dis. 25 2011 3
- (2011) J. Alzheimers Dis. , vol.25 , pp. 3
- Haapasalo, A.¹ Kovacs, D.M.²

16
- 78049374467
- B. De Strooper, and W. Annaert Annu. Rev. Cell Dev. Biol. 26 2010 235
- (2010) Annu. Rev. Cell Dev. Biol. , vol.26 , pp. 235
- De Strooper, B.¹ Annaert, W.²

17
- 21144455523
- For examples of clickable photoaffinity probes see
- For examples of clickable photoaffinity probes see, L. Ballell, K.J. Alink, M. Slijper, C. Versluis, R.M. Liskamp, and R.J. Pieters ChemBioChem 6 2005 291
- (2005) ChemBioChem , vol.6 , pp. 291
- Ballell, L.¹ Alink, K.J.² Slijper, M.³ Versluis, C.⁴ Liskamp, R.M.⁵ Pieters, R.J.⁶

18
- 33646462162
- S.A. Sieber, S. Niessen, H.S. Hoover, and B.F. Cravatt Nat. Chem. Biol. 2 2006 274
- (2006) Nat. Chem. Biol. , vol.2 , pp. 274
- Sieber, S.A.¹ Niessen, S.² Hoover, H.S.³ Cravatt, B.F.⁴

19
- 33846649707
- C.M. Salisbury, and B.F. Cravatt Proc. Natl. Acad. Sci. U.S.A. 104 2007 1171
- (2007) Proc. Natl. Acad. Sci. U.S.A. , vol.104 , pp. 1171
- Salisbury, C.M.¹ Cravatt, B.F.²

20
- 36749047362
- A.L. MacKinnon, J.L. Garrison, R.S. Hegde, and J. Taunton J. Am. Chem. Soc. 129 2007 14560
- (2007) J. Am. Chem. Soc. , vol.129 , pp. 14560
- MacKinnon, A.L.¹ Garrison, J.L.² Hegde, R.S.³ Taunton, J.⁴

21
- 76249107767
- K.A. Kalesh, D.S. Sim, J. Wang, K. Liu, Q. Lin, and S.Q. Yao Chem. Commun. 46 2010 1118
- (2010) Chem. Commun. , vol.46 , pp. 1118
- Kalesh, K.A.¹ Sim, D.S.² Wang, J.³ Liu, K.⁴ Lin, Q.⁵ Yao, S.Q.⁶

22
- 80053498767
- H. Shi, X. Cheng, S.K. Sze, and S.Q. Yao Chem. Commun. 47 2011 11306
- (2011) Chem. Commun. , vol.47 , pp. 11306
- Shi, H.¹ Cheng, X.² Sze, S.K.³ Yao, S.Q.⁴

23
- 79961161118
- J. Eirich, R. Orth, and S.A. Sieber J. Am. Chem. Soc. 133 2011 12144
- (2011) J. Am. Chem. Soc. , vol.133 , pp. 12144
- Eirich, J.¹ Orth, R.² Sieber, S.A.³

24
- 82455172862
- C.J. Crump, B.A. Fish, S.V. Castro, D.-M. Chau, N. Gertsik, K. Ahn, C. Stiff, N. Pozdnyakov, K.R. Bales, D.S. Johnson, and Y.-M. Li ACS Chem. Neurosci. 2 2011 705
- (2011) ACS Chem. Neurosci. , vol.2 , pp. 705
- Crump, C.J.¹ Fish, B.A.² Castro, S.V.³ Chau, D.-M.⁴ Gertsik, N.⁵ Ahn, K.⁶ Stiff, C.⁷ Pozdnyakov, N.⁸ Bales, K.R.⁹ Johnson, D.S.¹⁰ Li, Y.-M.¹¹

25
- 33747875977
- D.I. Rozkiewicz, D. Janczewski, W. Verboom, B.J. Ravoo, and D.N. Reinhoudt Angew. Chem., Int. Ed. 45 2006 5292
- (2006) Angew. Chem., Int. Ed. , vol.45 , pp. 5292
- Rozkiewicz, D.I.¹ Janczewski, D.² Verboom, W.³ Ravoo, B.J.⁴ Reinhoudt, D.N.⁵

26
- 5444256890
- J. Chun, Y.I. Yin, G. Yang, L. Tarassishin, and Y.M. Li J. Org. Chem. 69 2004 7344
- (2004) J. Org. Chem. , vol.69 , pp. 7344
- Chun, J.¹ Yin, Y.I.² Yang, G.³ Tarassishin, L.⁴ Li, Y.M.⁵

27
- 0000273282
- B.E. Evans, K.E. Rittle, C.F. Homnick, J.P. Springer, J. Hirshfield, and D.F. Veber J. Org. Chem. 50 1985 4615
- (1985) J. Org. Chem. , vol.50 , pp. 4615
- Evans, B.E.¹ Rittle, K.E.² Homnick, C.F.³ Springer, J.P.⁴ Hirshfield, J.⁵ Veber, D.F.⁶

28
- 0035945979
- A. Nadin, J.M. Sanchez Lopez, J.G. Neduvelil, and S.R. Thomas Tetrahedron 57 2001 1861
- (2001) Tetrahedron , vol.57 , pp. 1861
- Nadin, A.¹ Sanchez Lopez, J.M.² Neduvelil, J.G.³ Thomas, S.R.⁴

29
- 67650714664
- C.C. Shelton, Y. Tian, M.G. Frattini, and Y.M. Li Mol. Neurodegeneration 4 2009 22
- (2009) Mol. Neurodegeneration , vol.4 , pp. 22
- Shelton, C.C.¹ Tian, Y.² Frattini, M.G.³ Li, Y.M.⁴

30
- 73949087262
- C.C. Shelton, L. Zhu, D. Chau, L. Yang, R. Wang, H. Djaballah, H. Zheng, and Y.M. Li Proc. Natl. Acad. Sci. U.S.A. 106 2009 20228
- (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 20228
- Shelton, C.C.¹ Zhu, L.² Chau, D.³ Yang, L.⁴ Wang, R.⁵ Djaballah, H.⁶ Zheng, H.⁷ Li, Y.M.⁸

31
- 77957795414
- Y. Tian, C.J. Crump, and Y.M. Li J. Biol. Chem. 285 2010 32549
- (2010) J. Biol. Chem. , vol.285 , pp. 32549
- Tian, Y.¹ Crump, C.J.² Li, Y.M.³

32
- 0037150672
- A. Weihofen, K. Binns, M.K. Lemberg, K. Ashman, and B. Martoglio Science 296 2002 2215
- (2002) Science , vol.296 , pp. 2215
- Weihofen, A.¹ Binns, K.² Lemberg, M.K.³ Ashman, K.⁴ Martoglio, B.⁵

33
- 2442446430
- A.C. Nyborg, A.Y. Kornilova, K. Jansen, T.B. Ladd, M.S. Wolfe, and T.E. Golde J. Biol. Chem. 279 2004 15153
- (2004) J. Biol. Chem. , vol.279 , pp. 15153
- Nyborg, A.C.¹ Kornilova, A.Y.² Jansen, K.³ Ladd, T.B.⁴ Wolfe, M.S.⁵ Golde, T.E.⁶

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