Discrepant roles of CpG ODN on acute alcohol-induced liver injury in mice

International Immunopharmacology

Volumn 12, Issue 3, 2012, Pages 526-533

  Wang, Zhijun ^a   Wu, Xiuli ^a   Zhang, Yongsheng ^a   Zhou, Lei ^a   Li, Lina ^a   Yu, Yongli ^a   Wang, Liying ^a  

^a Basic Medical College   (China)

Author keywords

Alcohol; CpG ODN; IFN ; Liver injury; TLR9; TNF

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALPHA INTERFERON; CPG OLIGODEOXYNUCLEOTIDE; MESSENGER RNA; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; WATER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER CIRRHOSIS; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISEASE EXACERBATION; LIVER; LIVER TOXICITY; MALE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ALKALINE PHOSPHATASE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATITIS, ALCOHOLIC; INTERFERON-ALPHA; INTERFERON-BETA; LIVER; LIVER FUNCTION TESTS; MALE; MICE; MICE, INBRED ICR; OLIGODEOXYRIBONUCLEOTIDES; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84862813168     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2012.01.007     Document Type: Article

References (38)

1. F. Hong, W.H. Kim, Z. Tian, B. Jaruga, E. Ishac, and X. Shen Elevated interleukin-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol-induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-x(L) proteins Oncogene 21 2002 32 43 (Pubitemid 34076376)
2. R. Williams Global challenges in liver disease Hepatology 44 2006 521 526 (Pubitemid 44433707)
3. S.H. Ki, O. Park, M. Zheng, O. Morales-Ibanez, J.K. Kolls, and R. Bataller Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: role of signal transducer and activator of transcription 3 Hepatology 52 2010 1291 1300
4. W.I. Jeong, D. Osei-Hyiaman, O. Park, J. Liu, S. Bátkai, and P. Mukhopadhyay Paracrine activation of hepatic CB1 receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver Cell Metab 7 2008 227 235 (Pubitemid 351285525)
5. R.S. O'Shea, S. Dasarathy, and A.J. McCullough Practice Guideline Committee of the American Association for the Study of Liver Diseases, Practice Parameters Committee of the American College of Gastroenterology. Alcoholic liver disease Hepatology 51 2010 307 328
6. S. Zakhari, and T.K. Li Determinants of alcohol use and abuse: impact of quantity and frequency patterns on liver disease Hepatology 46 2007 2032 2039
7. P. Mandrekar, and G. Szabo Signalling pathways in alcohol-induced liver inflammation J Hepatol 50 2009 1258 1266
8. K. Nagata, H. Suzuki, and S. Sakaguchi Common pathogenic mechanism in development progression of liver injury caused by non-alcoholic or alcoholic steatohepatitis J Toxicol Sci 32 2007 453 468
9. A.G. Testro, and K. Visvanathan Toll-like receptors and their role in gastrointestinal disease J Gastroenterol Hepatol 24 2009 943 954
10. N. Horiguchi, L. Wang, P. Mukhopadhyay, O. Park, W.I. Jeong, and F. Lafdil Cell type-dependent pro- and anti-inflammatory role of signal transducer and activator of transcription 3 in alcoholic liver injury Gastroenterology 134 2008 1148 1158 (Pubitemid 351451970)
11. B.M. Thobe, M. Frink, F. Hildebrand, M.G. Schwacha, W.J. Hubbard, and M.A. Choudhry The role of MAPK in Kupffer cell toll-like receptor (TLR) 2-, TLR4-, and TLR9-mediated signaling following trauma-hemorrhage J Cell Physiol 210 2007 667 675 (Pubitemid 46185036)
12. J. Wu, M. Lu, Z. Meng, M. Trippler, R. Broering, and A. Szczeponek Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice Hepatology 46 2007 1769 1778
13. M. Schuchmann, F. Hermann, J. Herkel, R. van der Zee, P.R. Galle, and A.W. Lohse HSP60 and CpG-DNA-oligonucleotides differentially regulate LPS-tolerance of hepatic Kupffer cells Immunol Lett 93 2004 199 204 (Pubitemid 38670374)
14. V. Racanelli, and B. Rehermann The liver as an immunological organ Hepatology 43 2006 S54 S62
15. E. Seki, and D.A. Brenner Toll-like receptors and adaptor molecules in liver disease: update Hepatology 48 2008 322 335 (Pubitemid 351975556)
16. G. Szabo, and P. Mandrekar A recent perspective on alcohol, immunity, and host defense Alcohol Clin Exp Res 33 2009 220 232
17. M. Yin, M.D. Wheeler, H. Kono, B.U. Bradford, R.M. Gallucci, and M.I. Luster Essential role of tumor necrosis factor alpha in alcohol-induced liver injury in mice Gastroenterology 117 1999 942 952 (Pubitemid 29468238)
18. Z. Song, Z. Zhou, M. Song, S. Uriarte, T. Chen, and I. Deaciuc Alcohol-induced S-adenosylhomocysteine accumulation in the liver sensitizes to TNF hepatotoxicity: possible involvement of mitochondrial S-adenosylmethionine transport Biochem Pharmacol 74 2007 521 531 (Pubitemid 46963240)
19. Z. Song, Z. Zhou, S. Uriarte, L. Wang, Y.J. Kang, and T. Chen S-adenosylhomocysteine sensitizes to TNF-alpha hepatotoxicity in mice and liver cells: a possible etiological factor in alcoholic liver disease Hepatology 40 2004 989 997 (Pubitemid 39288133)
20. J.G. Pastorino, and J.B. Hoek Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition Hepatology 31 2000 1141 1152 (Pubitemid 30233240)
21. T. Gustot, A. Lemmers, C. Moreno, N. Nagy, E. Quertinmont, and C. Nicaise Differential liver sensitization to toll-like receptor pathways in mice with alcoholic fatty liver Hepatology 43 2006 989 1000 (Pubitemid 43724624)
22. C.A. Casey, A. Nanji, A.I. Cederbaum, M. Adachi, and T. Takahashi Alcoholic liver disease and apoptosis Alcohol Clin Exp Res 25 2001 49S 53S (Pubitemid 32545012)
23. R. Rao Endotoxemia and gut barrier dysfunction in alcoholic liver disease Hepatology 50 2009 638 644
24. B. Gao Innate immunity and steatohepatitis: a critical role of another toll (TLR-9) Gastroenterology 139 2010 27 30
25. S. Akira, S. Uematsu, and O. Takeuchi Pathogen recognition and innate immunity Cell 124 2006 783 801 (Pubitemid 43261452)
26. J. Vollmer, and A.M. Krieg Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists Adv Drug Deliv Rev 61 2009 195 204
27. M. Rehli Of mice and men: species variations of Toll-like receptor expression Trends Immunol 23 2002 375 378 (Pubitemid 34804626)
28. P.S. Lenert Classification, mechanisms of action, and therapeutic applications of inhibitory oligonucleotides for Toll-like receptors (TLR) 7 and 9 Mediators Inflamm 2010 2010 986596
29. D. Klinman, H. Shirota, D. Tross, T. Sato, and S. Klaschik Synthetic oligonucleotides as modulators of inflammation J Leukoc Biol 84 2008 958 964
30. A. Krug, S. Rothenfusser, V. Hornung, B. Jahrsdörfer, S. Blackwell, and Z.K. Ballas Identification of CpG oligonucleotide sequences with high induction of IFN-alpha/beta in plasmacytoid dendritic cells Eur J Immunol 31 2001 2154 2163 (Pubitemid 32640732)
31. L. Yang, L. Sun, X. Wu, L. Wang, H. Wei, and M. Wan Therapeutic injection of C-class CpG ODN in draining lymph node area induces potent activation of immune cells and rejection of established breast cancer in mice Clin Immunol 131 2009 426 437
32. H. Wei, H. Wei, H. Wang, Z. Tian, and R. Sun Activation of natural killer cells inhibits liver regeneration in toxin-induced liver injury model in mice via a tumor necrosis factor-alpha-dependent mechanism Am J Physiol Gastrointest Liver Physiol 299 2010 G275 G282
33. R. Yang, X. Han, R.L. Delude, and M.P. Fink Ethyl pyruvate ameliorates acute alcohol-induced liver injury and inflammation in mice J Lab Clin Med 142 2003 322 331 (Pubitemid 37487402)
34. P. Mathurin, and P. Deltenre Effect of binge drinking on the liver: an alarming public health issue? Gut 58 2009 613 617
35. D.E. Amacher Serum transaminase elevations as indicators of hepatic injury following the administration of drugs Regul Toxicol Pharmacol 27 1998 119 130 (Pubitemid 28377344)
36. M.R. Lucey, P. Mathurin, and T.R. Morgan Alcoholic hepatitis N Engl J Med 360 2009 2758 2769
37. K. Honda, Y. Ohba, H. Yanai, H. Negishi, T. Mizutani, and A. Takaoka Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction Nature 434 2005 1035 1040 (Pubitemid 40586053)
38. J. Petrasek, A. Dolganiuc, T. Csak, B. Nath, I. Hritz, and K. Kodys Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells Hepatology 53 2011 649 660