메뉴 건너뛰기




Volumn 22, Issue 4, 2012, Pages 624-636

Regulation of small RNA stability: Methylation and beyond

Author keywords

HEN1; methylation; miRNA; piRNA; RNA silencing; siRNA

Indexed keywords

BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; MICRORNA; NHLH1 PROTEIN, HUMAN; RNA BINDING PROTEIN; SMALL INTERFERING RNA; SMALL UNTRANSLATED RNA;

EID: 84862803181     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2012.36     Document Type: Review
Times cited : (200)

References (94)
  • 1
    • 34249076321 scopus 로고    scopus 로고
    • The regulation of genes and genomes by small RNAs
    • Ambros V, Chen X. The regulation of genes and genomes by small RNAs. Development 2007; 134:1635-1641.
    • (2007) Development , vol.134 , pp. 1635-1641
    • Ambros, V.1    Chen, X.2
  • 2
    • 70350227275 scopus 로고    scopus 로고
    • Small RNAs and their roles in plant development
    • Chen X. Small RNAs and their roles in plant development. Annu Rev Cell Dev Biol 2009; 25:21-44.
    • (2009) Annu Rev Cell Dev Biol , vol.25 , pp. 21-44
    • Chen, X.1
  • 3
    • 22144489833 scopus 로고    scopus 로고
    • RNAi: The nuts and bolts of the RISC machine
    • Filipowicz W. RNAi: The nuts and bolts of the RISC machine. Cell 2005; 122:17-20.
    • (2005) Cell , vol.122 , pp. 17-20
    • Filipowicz, W.1
  • 5
    • 78049275325 scopus 로고    scopus 로고
    • MicroRNAs with macro-effects on plant stress responses
    • Sunkar R. MicroRNAs with macro-effects on plant stress responses. Semin Cell Dev Biol 2010; 21:805-811.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 805-811
    • Sunkar, R.1
  • 6
    • 77955134510 scopus 로고    scopus 로고
    • Expression of microRNAs and its regulation in plants
    • Xie Z, Khanna K, Ruan S. Expression of microRNAs and its regulation in plants. Semin Cell Dev Biol 2010; 21:790-797.
    • (2010) Semin Cell Dev Biol , vol.21 , pp. 790-797
    • Xie, Z.1    Khanna, K.2    Ruan, S.3
  • 7
    • 78751477191 scopus 로고    scopus 로고
    • Gene silencing by microRNAs: Contributions of translational repression and mRNA decay
    • Huntzinger E, Izaurralde E. Gene silencing by microRNAs: Contributions of translational repression and mRNA decay. Nat Rev Genet 2011; 12:99-110.
    • (2011) Nat Rev Genet , vol.12 , pp. 99-110
    • Huntzinger, E.1    Izaurralde, E.2
  • 8
    • 0037123639 scopus 로고    scopus 로고
    • RNA-dependent RNA polymerases, viruses, and RNA silencing
    • Ahlquist P. RNA-dependent RNA polymerases, viruses, and RNA silencing. Science 2002; 296:1270-1273.
    • (2002) Science , vol.296 , pp. 1270-1273
    • Ahlquist, P.1
  • 9
    • 0037123601 scopus 로고    scopus 로고
    • Ancient pathways programmed by small RNAs
    • Zamore PD. Ancient pathways programmed by small RNAs. Science 2002; 296:1265-1269.
    • (2002) Science , vol.296 , pp. 1265-1269
    • Zamore, P.D.1
  • 10
    • 79955120337 scopus 로고    scopus 로고
    • RNA-directed DNA methylation
    • Zhang H, Zhu JK. RNA-directed DNA methylation. Curr Opin Plant Biol 2011; 14:142-147.
    • (2011) Curr Opin Plant Biol , vol.14 , pp. 142-147
    • Zhang, H.1    Zhu, J.K.2
  • 11
    • 33746502166 scopus 로고    scopus 로고
    • A distinct small RNA pathway silences selfish genetic elements in the germline
    • Vagin VV, Sigova A, Li C, Seitz H, Gvozdev V, Zamore PD. A distinct small RNA pathway silences selfish genetic elements in the germline. Science 2006; 313:320-324.
    • (2006) Science , vol.313 , pp. 320-324
    • Vagin, V.V.1    Sigova, A.2    Li, C.3    Seitz, H.4    Gvozdev, V.5    Zamore, P.D.6
  • 12
  • 13
    • 33947273235 scopus 로고    scopus 로고
    • Discrete small RNAgenerating loci as master regulators of transposon activity in Drosophila
    • Brennecke J, Aravin AA, Stark A, et al. Discrete small RNAgenerating loci as master regulators of transposon activity in Drosophila. Cell 2007; 128:1089-1103.
    • (2007) Cell , vol.128 , pp. 1089-1103
    • Brennecke, J.1    Aravin, A.A.2    Stark, A.3
  • 14
    • 33947390781 scopus 로고    scopus 로고
    • A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila
    • Gunawardane LS, Saito K, Nishida KM, et al. A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila. Science 2007; 315:1587-1590.
    • (2007) Science , vol.315 , pp. 1587-1590
    • Gunawardane, L.S.1    Saito, K.2    Nishida, K.M.3
  • 15
    • 52049098967 scopus 로고    scopus 로고
    • A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
    • Aravin AA, Sachidanandam R, Bourc'his D, et al. A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol Cell 2008; 31:785-799.
    • (2008) Mol Cell , vol.31 , pp. 785-799
    • Aravin, A.A.1    Sachidanandam, R.2    Bourc'his, D.3
  • 16
    • 41649116098 scopus 로고    scopus 로고
    • DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes
    • Kuramochi-Miyagawa S, Watanabe T, Gotoh K, et al. DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev 2008; 22:908-917.
    • (2008) Genes Dev , vol.22 , pp. 908-917
    • Kuramochi-Miyagawa, S.1    Watanabe, T.2    Gotoh, K.3
  • 17
    • 13644256193 scopus 로고    scopus 로고
    • Methylation as a crucial step in plant microRNA biogenesis
    • Yu B, Yang Z, Li J, et al. Methylation as a crucial step in plant microRNA biogenesis. Science 2005; 307:932-935.
    • (2005) Science , vol.307 , pp. 932-935
    • Yu, B.1    Yang, Z.2    Li, J.3
  • 18
    • 32644454064 scopus 로고    scopus 로고
    • HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3'-terminal nucleotide
    • Yang Z, Ebright YW, Yu B, Chen X. HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2' OH of the 3'-terminal nucleotide. Nucleic Acids Res 2006; 34:667-675.
    • (2006) Nucleic Acids Res , vol.34 , pp. 667-675
    • Yang, Z.1    Ebright, Y.W.2    Yu, B.3    Chen, X.4
  • 19
    • 34447291602 scopus 로고    scopus 로고
    • The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC
    • Horwich MD, Li C, Matranga C, et al. The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC. Curr Biol 2007; 17:1265-1272.
    • (2007) Curr Biol , vol.17 , pp. 1265-1272
    • Horwich, M.D.1    Li, C.2    Matranga, C.3
  • 20
    • 34047154356 scopus 로고    scopus 로고
    • A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish
    • Houwing S, Kamminga LM, Berezikov E, et al. A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in Zebrafish. Cell 2007; 129:69-82.
    • (2007) Cell , vol.129 , pp. 69-82
    • Houwing, S.1    Kamminga, L.M.2    Berezikov, E.3
  • 21
    • 78149285872 scopus 로고    scopus 로고
    • Hen1 is required for oocyte development and piRNA stability in zebrafish
    • Kamminga LM, Luteijn MJ, den Broeder MJ, et al. Hen1 is required for oocyte development and piRNA stability in zebrafish. EMBO J 2010; 29:3688-3700.
    • (2010) EMBO J , vol.29 , pp. 3688-3700
    • Kamminga, L.M.1    Luteijn, M.J.2    Den Broeder, M.J.3
  • 22
    • 42949137056 scopus 로고    scopus 로고
    • 2'-O-methyl modification in mouse piRNAs and its methylase
    • Kirino Y, Mourelatos Z. 2'-O-methyl modification in mouse piRNAs and its methylase. Nucleic Acids Symp Ser (Oxf) 2007; 417-418.
    • (2007) Nucleic Acids Symp Ser (Oxf) , pp. 417-418
    • Kirino, Y.1    Mourelatos, Z.2
  • 23
    • 34548366485 scopus 로고    scopus 로고
    • The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs
    • Kirino Y, Mourelatos Z. The mouse homolog of HEN1 is a potential methylase for Piwi-interacting RNAs. RNA 2007; 13:1397-1401.
    • (2007) RNA , vol.13 , pp. 1397-1401
    • Kirino, Y.1    Mourelatos, Z.2
  • 24
    • 34247259831 scopus 로고    scopus 로고
    • Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini
    • Kirino Y, Mourelatos Z. Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini. Nat Struct Mol Biol 2007; 14:347-348.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 347-348
    • Kirino, Y.1    Mourelatos, Z.2
  • 25
    • 34347378274 scopus 로고    scopus 로고
    • Pimet, the Drosophila homolog of HEN1, mediates 2'-Omethylation of Piwi- interacting RNAs at their 3' ends
    • Saito K, Sakaguchi Y, Suzuki T, Suzuki T, Siomi H, Siomi MC. Pimet, the Drosophila homolog of HEN1, mediates 2'-Omethylation of Piwi- interacting RNAs at their 3' ends. Genes Dev 2007; 21:1603-1608.
    • (2007) Genes Dev , vol.21 , pp. 1603-1608
    • Saito, K.1    Sakaguchi, Y.2    Suzuki, T.3    Suzuki, T.4    Siomi, H.5    Siomi, M.C.6
  • 26
    • 23944493378 scopus 로고    scopus 로고
    • Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis
    • Li J, Yang Z, Yu B, Liu J, Chen X. Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol 2005; 15:1501-1507.
    • (2005) Curr Biol , vol.15 , pp. 1501-1507
    • Li, J.1    Yang, Z.2    Yu, B.3    Liu, J.4    Chen, X.5
  • 27
    • 78249279641 scopus 로고    scopus 로고
    • WAVY LEAF1, an ortholog of Arabidopsis HEN1, regulates shoot development by maintaining MicroRNA and trans-acting small interfering RNA accumulation in rice
    • Abe M, Yoshikawa T, Nosaka M, et al. WAVY LEAF1, an ortholog of Arabidopsis HEN1, regulates shoot development by maintaining MicroRNA and trans-acting small interfering RNA accumulation in rice. Plant Physiol 2010; 154:1335-1346.
    • (2010) Plant Physiol , vol.154 , pp. 1335-1346
    • Abe, M.1    Yoshikawa, T.2    Nosaka, M.3
  • 28
    • 33845755755 scopus 로고    scopus 로고
    • Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis
    • Tkaczuk KL, Obarska A, Bujnicki JM. Molecular phylogenetics and comparative modeling of HEN1, a methyltransferase involved in plant microRNA biogenesis. BMC Evol Biol 2006; 6:6.
    • (2006) BMC Evol Biol , vol.6 , pp. 6
    • Tkaczuk, K.L.1    Obarska, A.2    Bujnicki, J.M.3
  • 29
    • 70349939426 scopus 로고    scopus 로고
    • Structural insights into mechanisms of the small RNA methyltransferase HEN1
    • Huang Y, Ji L, Huang Q, Vassylyev DG, Chen X, Ma JB. Structural insights into mechanisms of the small RNA methyltransferase HEN1. Nature 2009; 461:823-827.
    • (2009) Nature , vol.461 , pp. 823-827
    • Huang, Y.1    Ji, L.2    Huang, Q.3    Vassylyev, D.G.4    Chen, X.5    Ma, J.B.6
  • 30
    • 77957300063 scopus 로고    scopus 로고
    • Kinetic and functional analysis of the small RNA methyltransferase HEN1: The catalytic domain is essential for preferential modification of duplex RNA
    • Vilkaitis G, Plotnikova A, Klimasauskas S. Kinetic and functional analysis of the small RNA methyltransferase HEN1: The catalytic domain is essential for preferential modification of duplex RNA. RNA 2010; 16:1935-1942.
    • (2010) RNA , vol.16 , pp. 1935-1942
    • Vilkaitis, G.1    Plotnikova, A.2    Klimasauskas, S.3
  • 31
    • 33646589610 scopus 로고    scopus 로고
    • Transgenically expressed viral RNA silencing suppressors interfere with microRNA methylation in Arabidopsis
    • Yu B, Chapman EJ, Yang Z, Carrington JC, Chen X. Transgenically expressed viral RNA silencing suppressors interfere with microRNA methylation in Arabidopsis. FEBS Lett 2006; 580:3117-3120.
    • (2006) FEBS Lett , vol.580 , pp. 3117-3120
    • Yu, B.1    Chapman, E.J.2    Yang, Z.3    Carrington, J.C.4    Chen, X.5
  • 32
    • 47249134724 scopus 로고    scopus 로고
    • Inhibition of 3' modification of small RNAs in virus-infected plants require spatial and temporal co-expression of small RNAs and viral silencing- suppressor proteins
    • Lozsa R, Csorba T, Lakatos L, Burgyan J. Inhibition of 3' modification of small RNAs in virus-infected plants require spatial and temporal co-expression of small RNAs and viral silencing- suppressor proteins. Nucleic Acids Res 2008; 36:4099-4107.
    • (2008) Nucleic Acids Res , vol.36 , pp. 4099-4107
    • Lozsa, R.1    Csorba, T.2    Lakatos, L.3    Burgyan, J.4
  • 33
    • 80051774407 scopus 로고    scopus 로고
    • The helper component-proteinase of the Zucchini yellow mosaic virus inhibits the Hua Enhancer 1 methyltransferase activity in vitro
    • Jamous RM, Boonrod K, Fuellgrabe MW, Ali-Shtayeh MS, Krczal G, Wassenegger M. The helper component-proteinase of the Zucchini yellow mosaic virus inhibits the Hua Enhancer 1 methyltransferase activity in vitro. J Gen Virol 2011; 92:2222-2226.
    • (2011) J Gen Virol , vol.92 , pp. 2222-2226
    • Jamous, R.M.1    Boonrod, K.2    Fuellgrabe, M.W.3    Ali-Shtayeh, M.S.4    Krczal, G.5    Wassenegger, M.6
  • 34
    • 77957232609 scopus 로고    scopus 로고
    • SiRNAs compete with miRNAs for methylation by HEN1 in Arabidopsis
    • Yu B, Bi L, Zhai J, et al. siRNAs compete with miRNAs for methylation by HEN1 in Arabidopsis. Nucleic Acids Res 2010; 38:5844-5850.
    • (2010) Nucleic Acids Res , vol.38 , pp. 5844-5850
    • Yu, B.1    Bi, L.2    Zhai, J.3
  • 35
    • 62549159996 scopus 로고    scopus 로고
    • 2'-O-methylation stabilizes Piwiassociated small RNAs and ensures DNA elimination in Tetrahymena
    • Kurth HM, Mochizuki K. 2'-O-methylation stabilizes Piwiassociated small RNAs and ensures DNA elimination in Tetrahymena. RNA 2009; 15:675-685.
    • (2009) RNA , vol.15 , pp. 675-685
    • Kurth, H.M.1    Mochizuki, K.2
  • 36
    • 77953801618 scopus 로고    scopus 로고
    • Target RNA-directed trimming and tailing of small silencing RNAs
    • Ameres SL, Horwich MD, Hung JH, et al. Target RNA-directed trimming and tailing of small silencing RNAs. Science 2010; 328:1534-1539.
    • (2010) Science , vol.328 , pp. 1534-1539
    • Ameres, S.L.1    Horwich, M.D.2    Hung, J.H.3
  • 37
    • 29944442623 scopus 로고    scopus 로고
    • Two classes of endogenous small RNAs in Tetrahymena thermophila
    • Lee SR, Collins K. Two classes of endogenous small RNAs in Tetrahymena thermophila. Genes Dev 2006; 20:28-33.
    • (2006) Genes Dev , vol.20 , pp. 28-33
    • Lee, S.R.1    Collins, K.2
  • 38
    • 4444383501 scopus 로고    scopus 로고
    • Conjugation-specific small RNAs in Tetrahymena have predicted properties of scan (scn) RNAs involved in genome rearrangement
    • Mochizuki K, Gorovsky MA. Conjugation-specific small RNAs in Tetrahymena have predicted properties of scan (scn) RNAs involved in genome rearrangement. Genes Dev 2004; 18:2068-2073.
    • (2004) Genes Dev , vol.18 , pp. 2068-2073
    • Mochizuki, K.1    Gorovsky, M.A.2
  • 39
    • 0035872864 scopus 로고    scopus 로고
    • Nongenic, bidirectional transcription precedes and may promote developmental DNA deletion in Tetrahymena thermophila
    • Chalker DL, Yao MC. Nongenic, bidirectional transcription precedes and may promote developmental DNA deletion in Tetrahymena thermophila. Genes Dev 2001; 15:1287-1298.
    • (2001) Genes Dev , vol.15 , pp. 1287-1298
    • Chalker, D.L.1    Yao, M.C.2
  • 40
    • 26444477370 scopus 로고    scopus 로고
    • Germ line transcripts are processed by a Dicer-like protein that is essential for developmentally programmed genome rearrangements of Tetrahymena thermophila
    • Malone CD, Anderson AM, Motl JA, Rexer CH, Chalker DL. Germ line transcripts are processed by a Dicer-like protein that is essential for developmentally programmed genome rearrangements of Tetrahymena thermophila. Mol Cell Biol 2005; 25:9151-9164.
    • (2005) Mol Cell Biol , vol.25 , pp. 9151-9164
    • Malone, C.D.1    Anderson, A.M.2    Motl, J.A.3    Rexer, C.H.4    Chalker, D.L.5
  • 41
    • 11844263265 scopus 로고    scopus 로고
    • A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase
    • Mochizuki K, Gorovsky MA. A Dicer-like protein in Tetrahymena has distinct functions in genome rearrangement, chromosome segregation, and meiotic prophase. Genes Dev 2005; 19:77-89.
    • (2005) Genes Dev , vol.19 , pp. 77-89
    • Mochizuki, K.1    Gorovsky, M.A.2
  • 42
    • 75149121115 scopus 로고    scopus 로고
    • Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette
    • Jain R, Shuman S. Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette. RNA 2010; 16:316-323.
    • (2010) RNA , vol.16 , pp. 316-323
    • Jain, R.1    Shuman, S.2
  • 43
    • 70449566825 scopus 로고    scopus 로고
    • Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1
    • Mui Chan C, Zhou C, Brunzelle JS, Huang RH. Structural and biochemical insights into 2'-O-methylation at the 3'-terminal nucleotide of RNA by Hen1. Proc Natl Acad Sci USA 2009; 106:17699-17704.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 17699-17704
    • Mui Chan, C.1    Zhou, C.2    Brunzelle, J.S.3    Huang, R.H.4
  • 44
    • 70349847853 scopus 로고    scopus 로고
    • Reconstituting bacterial RNA repair and modification in vitro
    • Chan CM, Zhou C, Huang RH. Reconstituting bacterial RNA repair and modification in vitro. Science 2009; 326:247.
    • (2009) Science , vol.326 , pp. 247
    • Chan, C.M.1    Zhou, C.2    Huang, R.H.3
  • 45
    • 0037015239 scopus 로고    scopus 로고
    • CARPEL FACTORY a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana
    • Park W, Li J, Song R, Messing J, Chen X. CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr Biol 2002; 12:1484-1495.
    • (2002) Curr Biol , vol.12 , pp. 1484-1495
    • Park, W.1    Li, J.2    Song, R.3    Messing, J.4    Chen, X.5
  • 46
    • 34347355440 scopus 로고    scopus 로고
    • Baulcombe DC. miRNAs control gene expression in the singlecell alga Chlamydomonas reinhardtii
    • Molnar A, Schwach F, Studholme DJ, Thuenemann EC, Baulcombe DC. miRNAs control gene expression in the singlecell alga Chlamydomonas reinhardtii. Nature 2007; 447:1126-1129.
    • (2007) Nature , vol.447 , pp. 1126-1129
    • Molnar, A.1    Schwach, F.2    Studholme, D.J.3    Thuenemann, E.C.4
  • 47
    • 33845957402 scopus 로고    scopus 로고
    • Untemplated oligoadenylation promotes degradation of RISC-cleaved transcripts
    • Ibrahim F, Rohr J, Jeong WJ, Hesson J, Cerutti H. Untemplated oligoadenylation promotes degradation of RISC-cleaved transcripts. Science 2006; 314:1893.
    • (2006) Science , vol.314 , pp. 1893
    • Ibrahim, F.1    Rohr, J.2    Jeong, W.J.3    Hesson, J.4    Cerutti, H.5
  • 48
    • 77649255166 scopus 로고    scopus 로고
    • Uridylation of mature miRNAs and siRNAs by the MUT68 nucleotidyltransferase promotes their degradation in Chlamydomonas
    • Ibrahim F, Rymarquis LA, Kim EJ, et al. Uridylation of mature miRNAs and siRNAs by the MUT68 nucleotidyltransferase promotes their degradation in Chlamydomonas. Proc Natl Acad Sci USA 2010; 107:3906-3911.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 3906-3911
    • Ibrahim, F.1    Rymarquis, L.A.2    Kim, E.J.3
  • 49
    • 33845436047 scopus 로고    scopus 로고
    • Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans
    • Ruby JG, Jan C, Player C, et al. Large-scale sequencing reveals 21U-RNAs and additional microRNAs and endogenous siRNAs in C. elegans. Cell 2006; 127:1193-1207.
    • (2006) Cell , vol.127 , pp. 1193-1207
    • Ruby, J.G.1    Jan, C.2    Player, C.3
  • 50
    • 34250877841 scopus 로고    scopus 로고
    • A mammalian microRNA expression atlas based on small RNA library sequencing
    • Landgraf P, Rusu M, Sheridan R, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 2007; 129:1401-1414.
    • (2007) Cell , vol.129 , pp. 1401-1414
    • Landgraf, P.1    Rusu, M.2    Sheridan, R.3
  • 51
    • 80052527459 scopus 로고    scopus 로고
    • Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity
    • Wyman SK, Knouf EC, Parkin RK, et al. Post-transcriptional generation of miRNA variants by multiple nucleotidyl transferases contributes to miRNA transcriptome complexity. Genome Res 2011; 21:1450-1461.
    • (2011) Genome Res , vol.21 , pp. 1450-1461
    • Wyman, S.K.1    Knouf, E.C.2    Parkin, R.K.3
  • 52
    • 70349459257 scopus 로고    scopus 로고
    • The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation
    • Claycomb JM, Batista PJ, Pang KM, et al. The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 2009; 139:123-134.
    • (2009) Cell , vol.139 , pp. 123-134
    • Claycomb, J.M.1    Batista, P.J.2    Pang, K.M.3
  • 53
    • 70349476898 scopus 로고    scopus 로고
    • Distinct argonautemediated 22G-RNA pathways direct genome surveillance in the C. elegans germline
    • Gu W, Shirayama M, Conte D Jr, et al. Distinct argonautemediated 22G-RNA pathways direct genome surveillance in the C. elegans germline. Mol Cell 2009; 36:231-244.
    • (2009) Mol Cell , vol.36 , pp. 231-244
    • Gu, W.1    Shirayama, M.2    Conte Jr., D.3
  • 55
    • 3142729150 scopus 로고    scopus 로고
    • Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways
    • Okamura K, Ishizuka A, Siomi H, Siomi MC. Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways. Genes Dev 2004; 18:1655-1666.
    • (2004) Genes Dev , vol.18 , pp. 1655-1666
    • Okamura, K.1    Ishizuka, A.2    Siomi, H.3    Siomi, M.C.4
  • 57
    • 70349961432 scopus 로고    scopus 로고
    • Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes
    • Wang Y, Juranek S, Li H, et al. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature 2009; 461:754-761.
    • (2009) Nature , vol.461 , pp. 754-761
    • Wang, Y.1    Juranek, S.2    Li, H.3
  • 59
    • 61449186404 scopus 로고    scopus 로고
    • Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2
    • Katoh T, Sakaguchi Y, Miyauchi K, et al. Selective stabilization of mammalian microRNAs by 3' adenylation mediated by the cytoplasmic poly(A) polymerase GLD-2. Genes Dev 2009; 23:433-438.
    • (2009) Genes Dev , vol.23 , pp. 433-438
    • Katoh, T.1    Sakaguchi, Y.2    Miyauchi, K.3
  • 61
    • 0033826978 scopus 로고    scopus 로고
    • Effect of 3' terminal adenylic acid residue on the uridylation of human small RNAs in vitro and in frog oocytes
    • Chen Y, Sinha K, Perumal K, Reddy R. Effect of 3' terminal adenylic acid residue on the uridylation of human small RNAs in vitro and in frog oocytes. RNA 2000; 6:1277-1288.
    • (2000) RNA , vol.6 , pp. 1277-1288
    • Chen, Y.1    Sinha, K.2    Perumal, K.3    Reddy, R.4
  • 62
    • 81355125071 scopus 로고    scopus 로고
    • The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1
    • Han BW, Hung JH, Weng Z, Zamore PD, Ameres SL. The 3'-to-5' exoribonuclease Nibbler shapes the 3' ends of microRNAs bound to Drosophila Argonaute1. Curr Biol 2011; 21:1878-1887.
    • (2011) Curr Biol , vol.21 , pp. 1878-1887
    • Han, B.W.1    Hung, J.H.2    Weng, Z.3    Zamore, P.D.4    Ameres, S.L.5
  • 63
    • 81355129276 scopus 로고    scopus 로고
    • The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila
    • Liu N, Abe M, Sabin LR, et al. The exoribonuclease Nibbler controls 3' end processing of microRNAs in Drosophila. Curr Biol 2011; 21:1888-1893.
    • (2011) Curr Biol , vol.21 , pp. 1888-1893
    • Liu, N.1    Abe, M.2    Sabin, L.R.3
  • 64
    • 51749093103 scopus 로고    scopus 로고
    • Degradation of microRNAs by a family of exoribonucleases in Arabidopsis
    • Ramachandran V, Chen X. Degradation of microRNAs by a family of exoribonucleases in Arabidopsis. Science 2008; 321:1490-1492.
    • (2008) Science , vol.321 , pp. 1490-1492
    • Ramachandran, V.1    Chen, X.2
  • 65
    • 70349453924 scopus 로고    scopus 로고
    • Active turnover modulates mature microRNA activity in Caenorhabditis elegans
    • Chatterjee S, Grosshans H. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 2009; 461:546-549.
    • (2009) Nature , vol.461 , pp. 546-549
    • Chatterjee, S.1    Grosshans, H.2
  • 66
    • 37849008803 scopus 로고    scopus 로고
    • Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors
    • Gy I, Gasciolli V, Lauressergues D, et al. Arabidopsis FIERY1, XRN2, and XRN3 are endogenous RNA silencing suppressors. Plant Cell 2007; 19:3451-3461.
    • (2007) Plant Cell , vol.19 , pp. 3451-3461
    • Gy, I.1    Gasciolli, V.2    Lauressergues, D.3
  • 67
    • 1342346710 scopus 로고    scopus 로고
    • A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
    • Kennedy S, Wang D, Ruvkun G. A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans. Nature 2004; 427:645-649.
    • (2004) Nature , vol.427 , pp. 645-649
    • Kennedy, S.1    Wang, D.2    Ruvkun, G.3
  • 68
    • 34547497309 scopus 로고    scopus 로고
    • Target mimicry provides a new mechanism for regulation of microRNA activity
    • Franco-Zorrilla JM, Valli A, Todesco M, et al. Target mimicry provides a new mechanism for regulation of microRNA activity. Nat Genet 2007; 39:1033-1037.
    • (2007) Nat Genet , vol.39 , pp. 1033-1037
    • Franco-Zorrilla, J.M.1    Valli, A.2    Todesco, M.3
  • 69
    • 84855487497 scopus 로고    scopus 로고
    • Mimicry technology: Suppressing small RNA activity in plants
    • Rubio-Somoza I, Manavella PA. Mimicry technology: Suppressing small RNA activity in plants. Methods Mol Biol 2011; 732:131-137.
    • (2011) Methods Mol Biol , vol.732 , pp. 131-137
    • Rubio-Somoza, I.1    Manavella, P.A.2
  • 70
    • 77957328824 scopus 로고    scopus 로고
    • A collection of target mimics for comprehensive analysis of microRNA function in Arabidopsis thaliana
    • Todesco M, Rubio-Somoza I, Paz-Ares J, Weigel D. A collection of target mimics for comprehensive analysis of microRNA function in Arabidopsis thaliana. PLoS Genet 2010; 6:e1001031.
    • (2010) PLoS Genet , vol.6
    • Todesco, M.1    Rubio-Somoza, I.2    Paz-Ares, J.3    Weigel, D.4
  • 71
    • 77951164018 scopus 로고    scopus 로고
    • Differential regulation of microRNA stability
    • Bail S, Swerdel M, Liu H, et al. Differential regulation of microRNA stability. RNA 2010; 16:1032-1039.
    • (2010) RNA , vol.16 , pp. 1032-1039
    • Bail, S.1    Swerdel, M.2    Liu, H.3
  • 72
    • 80052992814 scopus 로고    scopus 로고
    • Cell adhesion-dependent control of microRNA decay
    • Kim YK, Yeo J, Ha M, Kim B, Kim VN. Cell adhesion-dependent control of microRNA decay. Mol Cell 2011; 43:1005-1014.
    • (2011) Mol Cell , vol.43 , pp. 1005-1014
    • Kim, Y.K.1    Yeo, J.2    Ha, M.3    Kim, B.4    Kim, V.N.5
  • 73
    • 65749093295 scopus 로고    scopus 로고
    • Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex
    • Sethi P, Lukiw WJ. Micro-RNA abundance and stability in human brain: Specific alterations in Alzheimer's disease temporal lobe neocortex. Neurosci Lett 2009; 459:100-104.
    • (2009) Neurosci Lett , vol.459 , pp. 100-104
    • Sethi, P.1    Lukiw, W.J.2
  • 74
    • 79961187973 scopus 로고    scopus 로고
    • Uracils at nucleotide position 9-11 are required for the rapid turnover of miR-29 family
    • Zhang Z, Zou J, Wang GK, et al. Uracils at nucleotide position 9-11 are required for the rapid turnover of miR-29 family. Nucleic Acids Res 2011; 39:4387-4395.
    • (2011) Nucleic Acids Res , vol.39 , pp. 4387-4395
    • Zhang, Z.1    Zou, J.2    Wang, G.K.3
  • 75
    • 34948817683 scopus 로고    scopus 로고
    • Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes
    • Huang J, Wang F, Argyris E, et al. Cellular microRNAs contribute to HIV-1 latency in resting primary CD4+ T lymphocytes. Nat Med 2007; 13:1241-1247.
    • (2007) Nat Med , vol.13 , pp. 1241-1247
    • Huang, J.1    Wang, F.2    Argyris, E.3
  • 76
    • 10744223020 scopus 로고    scopus 로고
    • Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes
    • Keegan LP, Leroy A, Sproul D, O'Connell MA. Adenosine deaminases acting on RNA (ADARs): RNA-editing enzymes. Genome Biol 2004; 5:209.
    • (2004) Genome Biol , vol.5 , pp. 209
    • Keegan, L.P.1    Leroy, A.2    Sproul, D.3    O'Connell, M.A.4
  • 77
    • 33845315229 scopus 로고    scopus 로고
    • Editor meets silencer: Crosstalk between RNA editing and RNA interference
    • Nishikura K. Editor meets silencer: Crosstalk between RNA editing and RNA interference. Nat Rev Mol Cell Biology 2006; 7:919-931.
    • (2006) Nat Rev Mol Cell Biology , vol.7 , pp. 919-931
    • Nishikura, K.1
  • 79
    • 30044443191 scopus 로고    scopus 로고
    • Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
    • Yang W, Chendrimada TP, Wang Q, et al. Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol 2006; 13:13-21.
    • (2006) Nat Struct Mol Biol , vol.13 , pp. 13-21
    • Yang, W.1    Chendrimada, T.P.2    Wang, Q.3
  • 80
    • 44649172429 scopus 로고    scopus 로고
    • MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo
    • Tang F, Hajkova P, O'Carroll D, et al. MicroRNAs are tightly associated with RNA-induced gene silencing complexes in vivo. Biochem Biophys Res Commun 2008; 372:24-29.
    • (2008) Biochem Biophys Res Commun , vol.372 , pp. 24-29
    • Tang, F.1    Hajkova, P.2    O'Carroll, D.3
  • 81
    • 36849048778 scopus 로고    scopus 로고
    • Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression
    • Diederichs S, Haber DA. Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell 2007; 131:1097-1108.
    • (2007) Cell , vol.131 , pp. 1097-1108
    • Diederichs, S.1    Haber, D.A.2
  • 82
    • 81255176919 scopus 로고    scopus 로고
    • Argonaute proteins regulate microRNA stability: Increased microRNA abundance by Argonaute proteins is due to microRNA stabilization
    • Winter J, Diederichs S. Argonaute proteins regulate microRNA stability: Increased microRNA abundance by Argonaute proteins is due to microRNA stabilization. RNA Biol 2011; 8:1149-1157.
    • (2011) RNA Biol , vol.8 , pp. 1149-1157
    • Winter, J.1    Diederichs, S.2
  • 83
    • 33645967150 scopus 로고    scopus 로고
    • AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1
    • Vaucheret H, Mallory AC, Bartel DP. AGO1 homeostasis entails coexpression of MIR168 and AGO1 and preferential stabilization of miR168 by AGO1. Mol Cell 2006; 22:129-136.
    • (2006) Mol Cell , vol.22 , pp. 129-136
    • Vaucheret, H.1    Mallory, A.C.2    Bartel, D.P.3
  • 84
    • 79955499404 scopus 로고    scopus 로고
    • Arabidopsis Argonaute 2 regulates innate immunity via miRNA393(*)-mediated silencing of a Golgi-localized SNARE gene, MEMB12
    • Zhang X, Zhao H, Gao S, et al. Arabidopsis Argonaute 2 regulates innate immunity via miRNA393(*)-mediated silencing of a Golgi-localized SNARE gene, MEMB12. Mol Cell 2011; 42:356-366.
    • (2011) Mol Cell , vol.42 , pp. 356-366
    • Zhang, X.1    Zhao, H.2    Gao, S.3
  • 85
    • 79953744170 scopus 로고    scopus 로고
    • ARGONAUTE10 and ARGONAUTE1 regulate the termination of floral stem cells through two microRNAs in Arabidopsis
    • Ji L, Liu X, Yan J, et al. ARGONAUTE10 and ARGONAUTE1 regulate the termination of floral stem cells through two microRNAs in Arabidopsis. PLoS Genet 2011; 7:e1001358.
    • (2011) PLoS Genet , vol.7
    • Ji, L.1    Liu, X.2    Yan, J.3
  • 86
    • 63349100127 scopus 로고    scopus 로고
    • The ARGONAUTE10 gene modulates shoot apical meristem maintenance and leaf polarity establishment by repressing miR165/166 in Arabidopsis
    • Nov 28. doi:10.1111/j.1365-313X.2008.03757.x
    • Liu Q, Yao X, Pi L, Wang H, Cui X, Huang H. The ARGONAUTE10 gene modulates shoot apical meristem maintenance and leaf polarity establishment by repressing miR165/166 in Arabidopsis. Plant J 2008 Nov 28. doi:10.1111/j.1365- 313X.2008.03757.x
    • (2008) Plant J
    • Liu, Q.1    Yao, X.2    Pi, L.3    Wang, H.4    Cui, X.5    Huang, H.6
  • 87
    • 79953857473 scopus 로고    scopus 로고
    • Arabidopsis Argonaute10 specifically sequesters miR166/165 to regulate shoot apical meristem development
    • Zhu H, Hu F, Wang R, et al. Arabidopsis Argonaute10 specifically sequesters miR166/165 to regulate shoot apical meristem development. Cell 2011; 145:242-256.
    • (2011) Cell , vol.145 , pp. 242-256
    • Zhu, H.1    Hu, F.2    Wang, R.3
  • 88
    • 77649158885 scopus 로고    scopus 로고
    • The Tetrahymena argonaute-binding protein Giw1p directs a mature argonautesiRNA complex to the nucleus
    • Noto T, Kurth HM, Kataoka K, et al. The Tetrahymena argonaute-binding protein Giw1p directs a mature argonautesiRNA complex to the nucleus. Cell 2010; 140:692-703.
    • (2010) Cell , vol.140 , pp. 692-703
    • Noto, T.1    Kurth, H.M.2    Kataoka, K.3
  • 89
    • 52949092251 scopus 로고    scopus 로고
    • The DNA/RNA-binding protein, translin, binds microRNA122a and increases its in vivo stability
    • Yu Z, Hecht NB. The DNA/RNA-binding protein, translin, binds microRNA122a and increases its in vivo stability. J Androl 2008; 29:572-579.
    • (2008) J Androl , vol.29 , pp. 572-579
    • Yu, Z.1    Hecht, N.B.2
  • 90
    • 68449090733 scopus 로고    scopus 로고
    • C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation
    • Liu Y, Ye X, Jiang F, et al. C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. Science 2009; 325:750-753.
    • (2009) Science , vol.325 , pp. 750-753
    • Liu, Y.1    Ye, X.2    Jiang, F.3
  • 91
    • 13544275929 scopus 로고    scopus 로고
    • ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells
    • Yang W, Wang Q, Howell KL, et al. ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells. J Biol Chem 2005; 280:3946-3953.
    • (2005) J Biol Chem , vol.280 , pp. 3946-3953
    • Yang, W.1    Wang, Q.2    Howell, K.L.3
  • 93
    • 83255187212 scopus 로고    scopus 로고
    • Current progress in the development of RNAi-based therapeutics for HIV-1
    • Zhou J, Rossi JJ. Current progress in the development of RNAi-based therapeutics for HIV-1. Gene Ther 2011; 18:1134-1138.
    • (2011) Gene Ther , vol.18 , pp. 1134-1138
    • Zhou, J.1    Rossi, J.J.2
  • 94
    • 84855502918 scopus 로고    scopus 로고
    • Exogenous plant MIR168a specifically targets mammalian LDLRAP1: Evidence of crosskingdom regulation by microRNA
    • Zhang L, Hou D, Chen X, et al. Exogenous plant MIR168a specifically targets mammalian LDLRAP1: Evidence of crosskingdom regulation by microRNA. Cell Res 2012; 22:107-126.
    • (2012) Cell Res , vol.22 , pp. 107-126
    • Zhang, L.1    Hou, D.2    Chen, X.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.