Transgenically expressed viral RNA silencing suppressors interfere with microRNA methylation in Arabidopsis

FEBS Letters

Volumn 580, Issue 13, 2006, Pages 3117-3120

  Yu, Bin ^a   Chapman, Elisabeth J ^b   Yang, Zhiyong ^a   Carrington, James C ^b   Chen, Xuemei ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b OREGON STATE UNIVERSITY   (United States)

Author keywords

HEN1; Methylation; microRNA microRNA*; Viral RNA silencing suppressor

Indexed keywords

MICRORNA; MITOCHONDRIAL RNA; RNA METHYLTRANSFERASE; VIRUS PROTEIN; VIRUS RNA;

ARABIDOPSIS; ARTICLE; CONTROLLED STUDY; ENZYME LOCALIZATION; GENE EXPRESSION; GENE SILENCING; IMMUNOPRECIPITATION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; RNA METHYLATION; SUPPRESSOR GENE;

ARABIDOPSIS; METHYLATION; MICRORNAS; PLANTS, GENETICALLY MODIFIED; RNA INTERFERENCE; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, VIRAL; SUPPRESSION, GENETIC; VIRAL CORE PROTEINS; VIRAL PROTEINS;

ARABIDOPSIS;

EID: 33646589610     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.04.063     Document Type: Article

References (28)

1. Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116 (2004) 281-297
2. Yu B., Yang Z., Li J., Minakhina S., Yang M., Padgett R.W., Steward R., and Chen X. Methylation as a crucial step in plant microRNA biogenesis. Science 307 (2005) 932-935
3. Li J., Yang Z., Yu B., Liu J., and Chen X. Methylation protects miRNAs and siRNAs from a 3′-end uridylation activity in Arabidopsis. Curr. Biol. 15 (2005) 1501-1507
4. Yang Z., Ebright Y.W., Yu B., and Chen X. HEN1 recognizes 21-24 nt small RNA duplexes and deposits a methyl group onto the 2′OH of the 3′ terminal nucleotide. Nucleic Acid Res. 34 (2006) 667-675
5. Ebhardt H.A., Thi E.P., Wang M.B., and Unrau P.H. Extensive 3′ modification of plant small RNAs is modulated by helper component-proteinase expression. Proc. Natl. Acad. Sci. USA 102 (2005) 13398-13403
6. Park W., Li J., Song R., Messing J., and Chen X. CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana. Curr. Biol. 12 (2002) 1484-1495
7. Boutet S., Vazquez F., Liu J., Beclin C., Fagard M., Gratias A., Morel J.B., Crete P., Chen X., and Vaucheret H. Arabidopsis HEN1: a genetic link between endogenous miRNA controlling development and siRNA controlling transgene silencing and virus resistance. Curr. Biol. 13 (2003) 843-848
8. Han M.H., Goud S., Song L., and Fedoroff N. The Arabidopsis double-stranded RNA-binding protein HYL1 plays a role in microRNA-mediated gene regulation. Proc. Natl. Acad. Sci. USA 101 (2004) 1093-1098
9. Xie Z., Johansen L.K., Gustafson A.M., Kasschau K.D., Lellis A.D., Zilberman D., Jacobsen S.E., and Carrington J.C. Genetic and functional diversification of small RNA pathways in plants. PLoS Biol. 2 (2004) E104
10. Voinnet O. Induction and suppression of RNA silencing: insights from viral infections. Nat. Rev. Genet. 6 (2005) 206-220
11. Kasschau K.D., Xie Z., Allen E., Llave C., Chapman E.J., Krizan K.A., and Carrington J.C. P1/HC-Pro, a viral suppressor of RNA silencing, interferes with Arabidopsis development and miRNA function. Dev. Cell 4 (2003) 205-217
12. Chapman E.J., Prokhnevsky A.I., Gopinath K., Dolja V.V., and Carrington J.C. Viral RNA silencing suppressors inhibit the microRNA pathway at an intermediate step. Genes Dev. 18 (2004) 1179-1186
13. Dunoyer P., Lecellier C.H., Parizotto E.A., Himber C., and Voinnet O. Probing the microRNA and small interfering RNA pathways with virus-encoded suppressors of RNA silencing. Plant Cell 16 (2004) 1235-1250
14. Reed J.C., Kasschau K.D., Prokhnevsky A.I., Gopinath K., Pogue G.P., Carrington J.C., and Dolja V.V. Suppressor of RNA silencing encoded by Beet yellows virus. Virology 306 (2003) 203-209
15. Voinnet O., Pinto V.M., and Baulcombe D.C. Suppression of gene silencing: a general strategy used by diverse DNA and RNA viruses of plants. Proc. Natl. Acad. Sci. USA 96 (1999) 14147-14152
16. Silhavy D., Molnár A., Lucioli A., Szittya G., Hornyik C., Tavazza M., and Burgyán J. A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs. EMBO J 21 (2002) 3070-3080
17. Anandalakshmi R., Pruss G.J., Ge X., Marathe R., Smith T.H., and Vance V.B. A viral suppressor of gene silencing in plants. Proc. Natl. Acad. Sci. USA 95 (1998) 13079-13084
18. Brigneti G., Voinnet O., Wan-Xiang L., Ding S.W., and Baulcombe D.C. Viral pathogenicity determinants are suppressors of transgene silencing. EMBO J 17 (1998) 6739-6746
19. Kasschau K.D., and Carrington J.C. A counter-defensive strategy of plant viruses: suppression of posttranscriptional gene silencing. Cell 95 (1998) 461-470
20. Lakatos, L., Csorba, T., Pantaleo, V., Chapman E.J., Carrington, J.C., Liu, Y.-P., Dolja, V.V., Calvino, L.F., Lopez-Moya, J.J., Burgyan, J. (in press) Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors. EMBO J.
21. Alefelder S., Patel B.K., and Eckstein F. Incorporation of terminal phosphorothioates into oligonucleotides. Nucleic Acids Res. 26 (1998) 4983-4988
22. Hutvagner G., McLachlan J., Pasquinelli A.E., Balint E., Tuschl T., and Zamore P.D. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293 (2001) 834-838
23. Papp I., Mette M.F., Aufsatz W., Daxinger L., Schauer S.E., Ray A., van der Winden J., Matzke J., and Matzke A.J. Evidence for nuclear processing of plant micro RNA and short interfering RNA precursors. Plant Physiol. 132 (2003) 1382-1390
24. Wang X.J., Reyes J.L., Chua N.H., and Gaasterland T. Arabidopsis thaliana microRNAs and their mRNA targets. Genome Biol. 5 (2004) R65
25. Uhrig J.F., Canto T., Marshall D., and MacFarlane S.A. Relocalization of nuclear ALY proteins to the cytoplasm by the tomato bushy stunt virus P19 pathogenicity protein. Plant Physiol. 135 (2004) 2411-2423
26. Akbergenov R., Si-Ammour A., Blevins T., Amin I., Kutter C., Vanderschuren H., Zhang P., Gruissem W., Meins F., Hohn J.T., and Pooggin M.M. Molecular characterization of geminivirus-derived small RNAs in different plant species. Nucleic Acids Res. 34 (2006) 436-444
27. Park M.Y., Wu G., Gonzalez-Sulser A., Vaucheret H., and Poethig R.S. Nuclear processing and export of microRNAs in Arabidopsis. Proc. Natl. Acad. Sci. USA 102 (2005) 3691-3696
28. Zamore P.D. Plant RNAi: how a viral silencing suppressor inactivates siRNA. Curr. Biol. 14 (2004) R198-R200