Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine

Neuropharmacology

Volumn 62, Issue 7, 2012, Pages 2239-2250

  Hauser, Terry A ^a   Hepler, Christopher D ^a   Kombo, David C ^a   Grinevich, Vladimir P ^a   Kiser, Melanie N ^a   Hooker, Dawn N ^a   Zhang, Jiahui ^a   Mountfort, Douglas ^b   Selwood, Andrew ^b   Akireddy, S Rao ^a   Letchworth, Sharon R ^a   Yohannes, Daniel ^a  

^a TARGACEPT INC   (United States)

^b CAWTHRON INSTITUTE   (New Zealand)

Author keywords

Gymnodimine; Marine toxins; Muscarinic; Nicotinic; Receptor selectivity; Spirolide

Indexed keywords

13 DESMETHYLSPIROLIDE C; GYMNODIMINE; MARINE TOXIN; MUSCARINIC RECEPTOR; NEUROTRANSMITTER; NICOTINE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN CORTEX; CELL LINE; CONTROLLED STUDY; DRUG ISOLATION; DRUG POTENCY; DRUG PURIFICATION; DRUG RECEPTOR BINDING; FEMALE; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; IC 50; MOLECULAR DOCKING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RAT; SENSITIVITY ANALYSIS;

EID: 84862797400     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.01.009     Document Type: Article

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