The marine phycotoxin gymnodimine targets muscular and neuronal nicotinic acetylcholine receptor subtypes with high affinity

Journal of Neurochemistry

Volumn 107, Issue 4, 2008, Pages 952-963

  Kharrat, Riadh ^a,b   Servent, Denis ^c   Girard, Emmanuelle ^a   Ouanounou, Gilles ^a   Amar, Muriel ^a   Marrouchi, Riadh ^b   Benoit, Evelyne ^a   Molgó, Jordi ^a,d  

^a LABORATOIRE DE NEUROBIOLOGIE CELLULAIRE ET MOLÉCULAIRE   (France)

^b PASTEUR INSTITUTE OF TUNIS   (Tunisia)

^c SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^d Bâtiments 32 33 ^*  (France)

Author keywords

Gymnodimine; Marine phycotoxins; Muscle nicotinic acetylcholine receptor; Neuromuscular junction; Neuronal nicotinic receptors

Indexed keywords

GYMNODIMINE; MARINE TOXIN; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CLAM; CONTROLLED STUDY; HUMAN; HUMAN CELL; MUSCLE CELL; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR FUNCTION; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; XENOPUS;

ACETYLCHOLINE; ANIMALS; BEHAVIOR, ANIMAL; BIVALVIA; BUNGAROTOXINS; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ELECTRIC STIMULATION; GENE EXPRESSION; HETEROCYCLIC COMPOUNDS, 3-RING; HUMANS; HYDROCARBONS, CYCLIC; IMINES; MALE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MUSCLE CELLS; NEUROMUSCULAR JUNCTION; OOCYTES; PATCH-CLAMP TECHNIQUES; PROTEIN BINDING; RECEPTORS, NICOTINIC; SYNAPTIC TRANSMISSION; XENOPUS LAEVIS;

ANURA; BIVALVIA;

EID: 54349109894     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05677.x     Document Type: Article

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