Overexpression of HMGA1 deregulates tumor growth via cdc25A and alters migration/invasion through a cdc25A-independent pathway in medulloblastoma

Acta Neuropathologica

Volumn 123, Issue 4, 2012, Pages 553-571

  Lau, Kin Mang ^a,b   Chan, Queeny Kwan Yi ^a   Pang, Jesse C S ^a,b   Ma, Fanny Man Ting ^a   Li, Kay K W ^a   Yeung, Walter Wai ^a   Cheng, Alfred S L ^b   Feng, Hai ^b   Chung, Nellie Y F ^a   Li, Hiu Ming ^a   Zhou, Liangfu ^c   Wang, Yin ^c   Mao, Ying ^c   Ng, Ho Keung ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP A PROTEIN; HIGH MOBILITY GROUP A1 PROTEIN; MICRORNA 124; MICRORNA 124A; PROTEIN CDC25A; PROTEIN TYROSINE PHOSPHATASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER PROGNOSIS; CELL GROWTH; CELL INVASION; CELL MIGRATION; CHROMOSOME 6P; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA BINDING; FILOPODIUM; GENETIC GAIN; GROWTH REGULATION; HUMAN; HUMAN TISSUE; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STRESS FIBER; TRANSCRIPTION REGULATION; TUMOR GROWTH; UPREGULATION;

ACTIN CYTOSKELETON; ANIMALS; ANTIVIRAL AGENTS; CDC25 PHOSPHATASES; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CEREBELLAR NEOPLASMS; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 17; CHROMOSOMES, HUMAN, PAIR 6; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORETIC MOBILITY SHIFT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKOUT TECHNIQUES; HMGA1A PROTEIN; HUMANS; MALE; MEDULLOBLASTOMA; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NETROPSIN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TIME FACTORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84862794859     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-011-0934-8     Document Type: Article

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