Human colorectal carcinomas express high levels of high mobility group HMGI(Y) proteins

Cancer Research

Volumn 56, Issue 8, 1996, Pages 1896-1901

  Fedele, Monica ^a   Bandiera, Antonella ^b   Chiappetta, Gennaro ^a   Battista, Sabrina ^a   Viglietto, Giuseppe ^a   Manfioletti, Guidalberto ^b   Casamassimi, Amelia ^a   Santoro, Massimo ^c   Giancotti, Vincenzo ^b   Fusco, Alfredo ^d  

^a NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY MEDITERRANEA OF REGGIO CALABRIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP PROTEIN;

ARTICLE; CARCINOGENESIS; CARCINOMA CELL; CELL TRANSFORMATION; COLORECTAL CARCINOMA; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; PHENOTYPE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; CELL LINE; COLON; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS; EPITHELIUM; FEMALE; FIBROBLASTS; GENE EXPRESSION; HIGH MOBILITY GROUP PROTEINS; HMGA1A PROTEIN; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RATS; REFERENCE VALUES; THYROID GLAND; THYROID NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 9244229589     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. Fashena, S. T., Reeves, R, and Ruddle, N. H. A poly(dA-dT) upstream activating sequence binds high mobility group I protein and contributes to lymphotoxin (tumor necrosis factor-β) gene regulation. Mol. Cell. Biol., 12: 894-903, 1992
2. Friedmann, M , Holth, L. T., Zoghbt, H. Y , and Reeves, R. Organization, inducible-expression and chromosome localization of the human HMGI(Y) non-histone protein gene Nucleic Acids Res., 21: 4259-4267, 1993
3. Skalnik, D. G., and Neufeld, E. J Sequence-specific binding of HMG-I(Y) to the proximal promoter of the gp91-phox gene. Biochem. Biophys. Res. Commun., 187: 563-569, 1992.
4. Solomon, M, Strauss, F., and Varshavsky, A. A mammalian high mobility group recognizes any stretch of six A-T base pairs in duplex DNA. Proc. Natl. Acad. Sci. USA, 83: 1276-1280, 1986
5. Reeves, R., and Nissen, M. S The AT DNA binding domain of mammalian high mobility group I chromosomal protein, A novel peptide motif for recognizing DNA structure J Biol Chem. 265, 8576-8582, 1990
6. Johnson, K R., Lehn, D. A., Elton, T. S., Barr, P. J . and Reeves, R. Complete murine cDNA sequence, genomic structure, and tissue expression of the high mobility group protein HMG I(Y) J Biol. Chem. 263: 18338-18342, 1988
7. Johnson, K. R., Lehn, D. A , and Reeves, R. Alternative processing of mRNA's coding for human HMG I and HMG Y proteins Mol Cell. Biol. 9 2114-2123, 1989.
8. Manfioletti, G , Giancotti, V . Bandiera, A., Buratti, E., Sautiewre, P., Cary, P., Crane-Robinson, C . Coles, B., and Goodwin, G. H. cDNA cloning of the HMGI-c phosphoprotein a nuclear protein associated with neoplastic and undifferentiated phenotypes Nucleic Acids Res., 19: 6793-6797, 1991.
9. Zhao, K., Kas, E , Gonzales, E , and Laemmli, U K. SAR-dependent mobilization of histone H1 by HMG-I/Y in vitro: HMG-I/Y is enriched in H1-depleted chromatin EMBO J, 12: 3237-3247, 1993.
10. Thanos, D., and Maniatis, T. The high mobility group protein HMG (Y) is required for NF-κB dependent virus induction of the human IFN-β gene Cell, 71: 777-789. 1992
11. Du, W., Thanos, D., and Maniatis. T The high mobility group protein is required for NF-κB-dependent virus induction of the human IFN-β gene. Cell, 74: 887-898, 1993.
12. Whitley, M Z, Thanos, D . Read, M A., Maniatis, T., and Collins, T A. A strinking similarity in the organization of the E-selectin and beta interferon gene promoters Mol Cell Biol., 14: 6464-6475, 1994
13. Schindler, U , and Baichwal, V. R. Three NF-κB binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression. Mol. Cell. Biol., 14 5820-5831, 1994
14. Zhou, X., Benson, K F., Ashar, H R., and Chada, K. Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C. Nature (Lond.), 376: 771-774, 1995.
15. Giancotti, V., Berlingieri, M. T., Di Fiore, P. P. Fusco, A., Vecchio, G , and Crane-Robinson. C Changes in nuclear proteins following transformation of rat thyroid epithelial cells by a murine sarcoma retroviros. Cancer Res., 45: 6051-6057, 1985
16. Giancotti, V , Pani, B., D'Andrea, P., Berlingieri, M. T., Di Fiore, P. P., Fusco, A., Vecchio, G., Philp, R., Crane-Robinson, C., Nicolas, R. H., Wright C. A., and Goodwin, G. H. Elevated levels of a specific class of nuclear phosphoroproteins in cells transformed with ras and v-mos oncogenes and by co-transfection with c-myc and polyoma middle T genes. EMBO J , 6: 1981-1987, 1987
17. Giancotti, V., Buratti, E . Perissin, L., Zorzet, S., Balmain, A., Portella, G., Fusco, A., and Goodwin, G. H. Analysis of the HMGI nuclear proteins in mouse neoplastic cells induced by different procedures Exp. Cell Res., 184: 538-545, 1989.
18. Ram, T G , Reeves, R., and Hosick, H. L Elevated high mobility group I(Y) gene expression is associated with progressive transformation of mouse mammary epithelial cells Cancer Res., 55, 2655-2660, 1993
19. Bussemakers, M J G, Van de Ven, W. J. M . Debruyne, F. M. J , and Schalken, J. Identification of high mobility group protein I(Y) as potential progression marker for prostate cancer by differential hybridization analysis. Cancer Res. 51: 606-611, 1991
20. Berlingieri, M T., Manfioletti, G., Santoro, M., Bandiera, A. Visconti, R , Giancotti, V. and Fusco, A. Inhibition of HMGI-C protein synthesis suppresses retrovirally induced neoplastic transformation of rat thyroid cells. Mol. Cell. Biol., 15: 1545-1553, 1995.
21. Ashar, H. R., Schoenberg Fejzo, M. Tkachenko, A., Zhou, X., Fletcher, J. A., Weremowicz, S., Morton, C C., and Chada, K. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell, 82: 57-65, 1995.
22. Schoenmakers, E. F. P. M., Wanschura, S , Mols, R., Bullerdiek, J Van den Berghe, H. and Van de Ven, W. J. M. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat. Genet., 10: 436-443, 1995.
23. Chiappetta, G., Bandiera, A , Berlingieri, M. T , Visconti, R , Manfioletti, G , Battista, S , Martinez-Tello, F. J., Santoro, M , Giancotti, V., and Fusco, A. The expression of the high mobility group HMGI(Y) proteins correlates with the malignant phenotype of human thyroid neoplasms. Oncogene, 10: 1307-1314, 1995
24. Fearon, E R., and Vogelstein. B. A genetic model for colorectal tumorigenesis. Cell, 61: 759-767, 1990.
25. Bodmer, W. F, Bailey, C. J., Bodmer, J., Bussey, H J R, Ellis, A., Gorman, P., Lucibello, F. C., Murday, V. A, Rider, S. H., Scambler, P., Sheer, D., Solomon, E., and Spurr, N. K. Localization of the gene for familial adenomatous polyposis on chromosome 5. Nature (Lond.), 328, 614-616, 1987.
26. Groden, J , Thliveris, A , Samowitz, W., Carlson, M , Gelbert, L., Albertson, H., Joslyn, G , Stevens, J , Spirio, L., Robertson, M., Sargeant, L . Krapcho, K., Wolff, E , Burt, R , Hughes, J. P., Warrington, J., McPherson, J., Wasmuth, J., Le Paslier, D , Abderrahim, H , Cohen, D , Leppert, M., and White, R. Identification and characterization of the familial adenomatous polyposis coli gene. Cell, 66: 589-600, 1991.
27. Bos, J. L., Fearon, E. R., Hamilton, S. R., Verlaan-de Vries, M., van Boom, J. H., van der Eb, A. J., and Vogelstein, B. Prevalence of ras gene mutations in human colorectal cancers. Nature (Lond.), 327 293-297, 1987.
28. Forrester, K., Almoguera, C., Han, K., Grizzle, W. E., and Perucho, M . Detection of high incidence of Ki-ras oncogenes during human colon tumorigenesis. Nature (Lond.), 327: 298-303, 1987.
29. Campo, E. De la Calle-Martin, O., Miquel, R., Palacin, A., Romero, M., Fabregart, V., Vives, J., Cardesa, A., and Yague, J. Loss of p53 gene and p53 protein expression in human colorectal carcinomas. Cancer Res., 51: 4436-4424, 1991
30. Hollstein, M., Sidransky, D, Vogelstein, B., and Harris, C. C p53 mutations in human cancers Science (Washington DC), 253. 49-53, 1991.
31. Fearon, E. R., Cho, K. R. Nigro, J. M., Kern, S. E., Simons, J. W., Ruppert, J. M., Hamilton, S. R., Preisinger, A C., Thomas, G., Kinzler, K W., and Vogelstein, B. Identification of a chromosome 18q that is altered in colorectal carcinogenesis. Science (Washington DC), 247. 49-56, 1990
32. Chomczynski, P., and Sacchi, N. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chlorophorm extraction. Anal Biochem., 162: 156-159, 1987.
33. Sambrook, J., Fritsch, E F., and Maniatis, T. Molecular Cloning: A Laboratory Manual, 2nd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
34. Tokunaga, K., Taniguchi, H., Yoda, K., Shimizu, M., and Sakyama, S. Nucleotide sequence of a full-length cDNA for mouse cytoskeletal β-actin mRNA. Nucleic Acids Res., 14: 2829-2836, 1986.
35. Giancotti, V , Bandiera, A., Ciani, L., Santoro, D., Crane-Robinson, C., Goodwin, G. H., Baiocchi, M., Dolcetti, R., and Casetta, B. High -mobility-group (HMG) proteins and histone H1 subtypes expression in normal and tumor tissues of mouse. Eur. J. Biochem., 213: 825-830, 1993.
36. Tmimi, Y , van der Poel, H. G., Denyn, M M , Umbas, R, Karthaus, H. F. M., Debruyne, F. M. J., and Shalken, J. A. Increased expression of high mobility group protein 1(Y) in high grade prostate cancer detemined by in situ hybridization. Cancer Res., 53: 5512-5516, 1993
37. Mulcahy, H E., Duffy, M. J, Gibbons, D, McCarthy, P. Parfrey, N. A., O'Donoghue, D P., and Sheahan, K. Urokinase-type plasminogen activator and outcome in Dukes' B colorectal cancer. Lancet, 344: 583-584, 1994.