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Volumn 97, Issue 1, 2012, Pages 1-13

Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease

Author keywords

Alzheimer's disease; Cognitive dysfunction; Neurodegeneration; Parkinson disease; Receptors

Indexed keywords

BETA ADRENERGIC RECEPTOR; CHOLINERGIC RECEPTOR; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE 1; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE RECEPTOR; LEVODOPA; MITOGEN ACTIVATED PROTEIN KINASE 3; N [4 (2 CYANOPHENYL) 1 PIPERAZINYLMETHYL] 3 METHYLBENZAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PERGOLIDE; SEROTONIN 1A RECEPTOR; SEROTONIN 3 RECEPTOR; SEROTONIN RECEPTOR; TANDOSPIRONE;

EID: 84862789284     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2012.02.002     Document Type: Review
Times cited : (231)

References (184)
  • 2
    • 0031031846 scopus 로고    scopus 로고
    • Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: a study with positron emission tomography and [11C]raclopride
    • Antonini A., Schwarz J., Oertel W.H., Pogarell O., Leenders K.L. Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: a study with positron emission tomography and [11C]raclopride. Mov. Disord. 1997, 12:33-38.
    • (1997) Mov. Disord. , vol.12 , pp. 33-38
    • Antonini, A.1    Schwarz, J.2    Oertel, W.H.3    Pogarell, O.4    Leenders, K.L.5
  • 3
    • 0028868355 scopus 로고
    • Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease
    • Antonini A., Vontobel P., Psylla M., Günther I., Maguire P.R., Missimer J., Leenders K.L. Complementary positron emission tomographic studies of the striatal dopaminergic system in Parkinson's disease. Arch. Neurol. 1995, 52(12):1183-1190.
    • (1995) Arch. Neurol. , vol.52 , Issue.12 , pp. 1183-1190
    • Antonini, A.1    Vontobel, P.2    Psylla, M.3    Günther, I.4    Maguire, P.R.5    Missimer, J.6    Leenders, K.L.7
  • 4
    • 0031467450 scopus 로고    scopus 로고
    • Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease
    • Antonini A., Leenders K.L., Vontobel P., Maguire R.P., Missimer J., Psylla M., Gunther I. Complementary PET studies of striatal neuronal function in the differential diagnosis between multiple system atrophy and Parkinson's disease. Brain 1997, 120(Pt 12):2187-2195.
    • (1997) Brain , vol.120 , Issue.PART 12 , pp. 2187-2195
    • Antonini, A.1    Leenders, K.L.2    Vontobel, P.3    Maguire, R.P.4    Missimer, J.5    Psylla, M.6    Gunther, I.7
  • 5
    • 0036810329 scopus 로고    scopus 로고
    • Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies
    • Auld D.S., Kornecook T.J., Bastianetto S., Quirion R. Alzheimer's disease and the basal forebrain cholinergic system: relations to beta-amyloid peptides, cognition, and treatment strategies. Prog. Neurobiol. 2002, 68:209-245.
    • (2002) Prog. Neurobiol. , vol.68 , pp. 209-245
    • Auld, D.S.1    Kornecook, T.J.2    Bastianetto, S.3    Quirion, R.4
  • 6
    • 77951904180 scopus 로고    scopus 로고
    • Neuronal nicotinic acetylcholine receptor-cholesterol crosstalk in Alzheimer's disease
    • Barrantes F.J., Borroni V., Vallés S. Neuronal nicotinic acetylcholine receptor-cholesterol crosstalk in Alzheimer's disease. FEBS Lett. 2010, 584(9):1856-1863.
    • (2010) FEBS Lett. , vol.584 , Issue.9 , pp. 1856-1863
    • Barrantes, F.J.1    Borroni, V.2    Vallés, S.3
  • 7
    • 79952032110 scopus 로고    scopus 로고
    • The physiology, signaling, and pharmacology of dopamine receptors
    • Beaulieu J.M., Gainetdinov R.R. The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol. Rev. 2011, 63:182-217.
    • (2011) Pharmacol. Rev. , vol.63 , pp. 182-217
    • Beaulieu, J.M.1    Gainetdinov, R.R.2
  • 9
    • 33751178666 scopus 로고    scopus 로고
    • Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice
    • Beaulieu J.M., Sotnikova T.D., Gainetdinov R.R., Caron M.G. Paradoxical striatal cellular signaling responses to psychostimulants in hyperactive mice. J. Biol. Chem. 2006, 281:32072-32080.
    • (2006) J. Biol. Chem. , vol.281 , pp. 32072-32080
    • Beaulieu, J.M.1    Sotnikova, T.D.2    Gainetdinov, R.R.3    Caron, M.G.4
  • 11
    • 34848863031 scopus 로고    scopus 로고
    • Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats
    • Belujon P., Bezard E., Taupignon A., Bioulac B., Benazzouz A. Noradrenergic modulation of subthalamic nucleus activity: behavioral and electrophysiological evidence in intact and 6-hydroxydopamine-lesioned rats. J. Neurosci. 2007, 27(36):9595-9606.
    • (2007) J. Neurosci. , vol.27 , Issue.36 , pp. 9595-9606
    • Belujon, P.1    Bezard, E.2    Taupignon, A.3    Bioulac, B.4    Benazzouz, A.5
  • 12
    • 0037102726 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease
    • Bi H., Sze C.I. N-methyl-d-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease. J. Neurol. Sci. 2002, 200(1-2):11-18.
    • (2002) J. Neurol. Sci. , vol.200 , Issue.1-2 , pp. 11-18
    • Bi, H.1    Sze, C.I.2
  • 13
    • 34848925196 scopus 로고    scopus 로고
    • Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways
    • Bitner R.S., Bunnelle W.H., Anderson D.J., Briggs C.A., Buccafusco J., et al. Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways. J. Neurosci. 2007, 27(39):10578-10587.
    • (2007) J. Neurosci. , vol.27 , Issue.39 , pp. 10578-10587
    • Bitner, R.S.1    Bunnelle, W.H.2    Anderson, D.J.3    Briggs, C.A.4    Buccafusco, J.5
  • 14
    • 0027164360 scopus 로고
    • Loss of brain 5-HT2 receptors in Alzheimer's disease. In vivo assessment with positron emission tomography and [18F]setoperone
    • Blin J., Baron J.C., Dubois B., Crouzel C., Fiorelli M., Attar-Levy D., Pillon B., Fournier D., Vidailhet M., Agid Y. Loss of brain 5-HT2 receptors in Alzheimer's disease. In vivo assessment with positron emission tomography and [18F]setoperone. Brain 1993, 116(Pt 3):497-510.
    • (1993) Brain , vol.116 , Issue.PART 3 , pp. 497-510
    • Blin, J.1    Baron, J.C.2    Dubois, B.3    Crouzel, C.4    Fiorelli, M.5    Attar-Levy, D.6    Pillon, B.7    Fournier, D.8    Vidailhet, M.9    Agid, Y.10
  • 15
    • 33846846102 scopus 로고    scopus 로고
    • The NMDA receptor antagonist CPP blocks the effects of predator stress on pCREB in brain regions involved in fearful and anxious behavior
    • Blundell J., Adamec R. The NMDA receptor antagonist CPP blocks the effects of predator stress on pCREB in brain regions involved in fearful and anxious behavior. Brain Res. 2007, 1136(1):59-76.
    • (2007) Brain Res. , vol.1136 , Issue.1 , pp. 59-76
    • Blundell, J.1    Adamec, R.2
  • 17
    • 0021682595 scopus 로고
    • Adrenergic receptors in Parkinson's disease
    • Cash R., Ruberg M., Raisman R., Agid Y. Adrenergic receptors in Parkinson's disease. Brain Res. 1984, 322:269-275.
    • (1984) Brain Res. , vol.322 , pp. 269-275
    • Cash, R.1    Ruberg, M.2    Raisman, R.3    Agid, Y.4
  • 18
    • 0021846563 scopus 로고
    • Adrenergic receptors on cerebral microvessels in control and Parkinsonian subjects
    • Cash R., Lasbennes F., Sercombe R., Seylaz J., Agid Y. Adrenergic receptors on cerebral microvessels in control and Parkinsonian subjects. Life Sci. 1985, 37:531-536.
    • (1985) Life Sci. , vol.37 , pp. 531-536
    • Cash, R.1    Lasbennes, F.2    Sercombe, R.3    Seylaz, J.4    Agid, Y.5
  • 19
    • 0022508011 scopus 로고
    • Cellular localization of adrenergic receptors in rat and human brain
    • Cash R., Raisman R., Lanfumey L., Ploska A., Agid Y. Cellular localization of adrenergic receptors in rat and human brain. Brain Res. 1986, 370:127-135.
    • (1986) Brain Res. , vol.370 , pp. 127-135
    • Cash, R.1    Raisman, R.2    Lanfumey, L.3    Ploska, A.4    Agid, Y.5
  • 20
    • 0035819054 scopus 로고    scopus 로고
    • Voltage-gated channels block nicotinic regulation of CREB phosphorylation and gene expression in neurons
    • Chang K.T., Berg D.K. Voltage-gated channels block nicotinic regulation of CREB phosphorylation and gene expression in neurons. Neuron 2001, 32:855-865.
    • (2001) Neuron , vol.32 , pp. 855-865
    • Chang, K.T.1    Berg, D.K.2
  • 22
    • 77952360311 scopus 로고    scopus 로고
    • DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-)) injected mice through preventing the dysfunction of alpha7 nicotinic receptor
    • Chen L., Wang H., Zhang Z., Li Z., He D., Sokabe M. DMXB (GTS-21) ameliorates the cognitive deficits in beta amyloid(25-35(-)) injected mice through preventing the dysfunction of alpha7 nicotinic receptor. J. Neurosci. Res. 2010, 88:1784-1794.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 1784-1794
    • Chen, L.1    Wang, H.2    Zhang, Z.3    Li, Z.4    He, D.5    Sokabe, M.6
  • 24
    • 61849125277 scopus 로고    scopus 로고
    • Dopamine and cognitive functioning in de novo subjects with Parkinson's disease: effects of pramipexole and pergolide on working memory
    • Costa A., Peppe A., Dell'Agnello G., Caltagirone C., Carlesimo G.A. Dopamine and cognitive functioning in de novo subjects with Parkinson's disease: effects of pramipexole and pergolide on working memory. Neuropsychologia 2009, 47(5):1374-1381.
    • (2009) Neuropsychologia , vol.47 , Issue.5 , pp. 1374-1381
    • Costa, A.1    Peppe, A.2    Dell'Agnello, G.3    Caltagirone, C.4    Carlesimo, G.A.5
  • 25
    • 37149055806 scopus 로고    scopus 로고
    • Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease
    • Counts S.E., He B., Che S., Ikonomovic M.D., DeKosky S.T., Ginsberg S.D., Mufson E.J. Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease. Arch. Neurol. 2007, 64:1771-1776.
    • (2007) Arch. Neurol. , vol.64 , pp. 1771-1776
    • Counts, S.E.1    He, B.2    Che, S.3    Ikonomovic, M.D.4    DeKosky, S.T.5    Ginsberg, S.D.6    Mufson, E.J.7
  • 27
    • 57849111780 scopus 로고    scopus 로고
    • Selective 5-HT6 receptor blockade improves spatial recognition memory and reverses age-related deficits in spatial recognition memory in the mouse
    • Da Silva Costa V., Duchatelle P., Boulouard M., Dauphin F. Selective 5-HT6 receptor blockade improves spatial recognition memory and reverses age-related deficits in spatial recognition memory in the mouse. Neuropsychopharmacology 2009, 34(2):488-500.
    • (2009) Neuropsychopharmacology , vol.34 , Issue.2 , pp. 488-500
    • Da Silva Costa, V.1    Duchatelle, P.2    Boulouard, M.3    Dauphin, F.4
  • 28
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt N.C. Glutamate uptake. Prog. Neurobiol. 2001, 65(1):1-105.
    • (2001) Prog. Neurobiol. , vol.65 , Issue.1 , pp. 1-105
    • Danbolt, N.C.1
  • 29
    • 24944502364 scopus 로고    scopus 로고
    • Dopamine-glutamate interaction and antipsychotics mechanism of action: implication for new pharmacological strategies in psychosis
    • de Bartolomeis A., Fiore G., Iasevoli F. Dopamine-glutamate interaction and antipsychotics mechanism of action: implication for new pharmacological strategies in psychosis. Curr. Pharm. Des. 2005, 11(27):3561-3594.
    • (2005) Curr. Pharm. Des. , vol.11 , Issue.27 , pp. 3561-3594
    • de Bartolomeis, A.1    Fiore, G.2    Iasevoli, F.3
  • 30
    • 34249672242 scopus 로고    scopus 로고
    • Abeta oligomers induce neuronal oxidative stress through an N-methyl-d-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine
    • De Felice F.G., Velasco P.T., Lambert M.P., Viola K., Fernandez S.J., Ferreira S.T., Klein W.L. Abeta oligomers induce neuronal oxidative stress through an N-methyl-d-aspartate receptor-dependent mechanism that is blocked by the Alzheimer drug memantine. J. Biol. Chem. 2007, 282:11590-11601.
    • (2007) J. Biol. Chem. , vol.282 , pp. 11590-11601
    • De Felice, F.G.1    Velasco, P.T.2    Lambert, M.P.3    Viola, K.4    Fernandez, S.J.5    Ferreira, S.T.6    Klein, W.L.7
  • 32
    • 0026002790 scopus 로고
    • Binding to the glycine site of the NMDA receptor complex in brains of patients with Alzheimer's disease
    • Del Bel E.A., Slater P. Binding to the glycine site of the NMDA receptor complex in brains of patients with Alzheimer's disease. Neurosci. Lett. 1991, 131:75-78.
    • (1991) Neurosci. Lett. , vol.131 , pp. 75-78
    • Del Bel, E.A.1    Slater, P.2
  • 33
    • 0033974271 scopus 로고    scopus 로고
    • Alterations in subunit expression, composition, and phosphorylation of striatal N-methyl-d-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease
    • Dunah A.W., Wang Y., Yasuda R.P., Kameyama K., Huganir R.L., Wolfe B.B., Standaert D.G. Alterations in subunit expression, composition, and phosphorylation of striatal N-methyl-d-aspartate glutamate receptors in a rat 6-hydroxydopamine model of Parkinson's disease. Mol. Pharmacol. 2000, 57:342-352.
    • (2000) Mol. Pharmacol. , vol.57 , pp. 342-352
    • Dunah, A.W.1    Wang, Y.2    Yasuda, R.P.3    Kameyama, K.4    Huganir, R.L.5    Wolfe, B.B.6    Standaert, D.G.7
  • 34
    • 67650484613 scopus 로고    scopus 로고
    • Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease
    • Dziewczapolski G., Glogowski C.M., Masliah E., Heinemann S.F. Deletion of the alpha 7 nicotinic acetylcholine receptor gene improves cognitive deficits and synaptic pathology in a mouse model of Alzheimer's disease. J. Neurosci. 2009, 29:8805-8815.
    • (2009) J. Neurosci. , vol.29 , pp. 8805-8815
    • Dziewczapolski, G.1    Glogowski, C.M.2    Masliah, E.3    Heinemann, S.F.4
  • 35
    • 34248534333 scopus 로고    scopus 로고
    • Insights into the role of dopamine receptor systems in learning and memory
    • El-Ghundi M., O'Dowd B.F., George S.R. Insights into the role of dopamine receptor systems in learning and memory. Rev. Neurosci. 2007, 18:37-66.
    • (2007) Rev. Neurosci. , vol.18 , pp. 37-66
    • El-Ghundi, M.1    O'Dowd, B.F.2    George, S.R.3
  • 37
    • 34250739480 scopus 로고    scopus 로고
    • Advances in the discovery of novel positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor
    • Faghih R., Gfesser G.A., Gopalakrishnan M. Advances in the discovery of novel positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor. Recent Pat. CNS Drug Discov. 2007, 2:99-106.
    • (2007) Recent Pat. CNS Drug Discov. , vol.2 , pp. 99-106
    • Faghih, R.1    Gfesser, G.A.2    Gopalakrishnan, M.3
  • 38
    • 23844448681 scopus 로고    scopus 로고
    • N-methyl-d-aspartate receptor and apoptosis in Alzheimer's disease and multiinfarct dementia
    • Fang M., Li J., Tiu S.C., Zhang L., Wang M., Yew D.T. N-methyl-d-aspartate receptor and apoptosis in Alzheimer's disease and multiinfarct dementia. J. Neurosci. Res. 2005, 81:269-274.
    • (2005) J. Neurosci. Res. , vol.81 , pp. 269-274
    • Fang, M.1    Li, J.2    Tiu, S.C.3    Zhang, L.4    Wang, M.5    Yew, D.T.6
  • 39
    • 33744997152 scopus 로고    scopus 로고
    • The stepping test and its learning process in different degrees of unilateral striatal lesions by 6-hydroxydopamine in rats
    • Fang X., Sugiyama K., Akamine S., Namba H. The stepping test and its learning process in different degrees of unilateral striatal lesions by 6-hydroxydopamine in rats. Neurosci. Res. 2006, 55(4):403-409.
    • (2006) Neurosci. Res. , vol.55 , Issue.4 , pp. 403-409
    • Fang, X.1    Sugiyama, K.2    Akamine, S.3    Namba, H.4
  • 40
    • 11844302788 scopus 로고    scopus 로고
    • Effects of age and dopamine D2L receptor-deficiency on motor and learning functions
    • Fetsko L.A., Xu R., Wang Y. Effects of age and dopamine D2L receptor-deficiency on motor and learning functions. Neurobiol. Aging 2005, 26(4):521-530.
    • (2005) Neurobiol. Aging , vol.26 , Issue.4 , pp. 521-530
    • Fetsko, L.A.1    Xu, R.2    Wang, Y.3
  • 42
    • 0842308152 scopus 로고    scopus 로고
    • Differential involvement of 5-HT(1B/1D) and 5-HT6 receptors in cognitive and non-cognitive symptoms in Alzheimer's disease
    • Garcia-Alloza M., Hirst W.D., Chen C.P., Lasheras B., Francis P.T., Ramirez M.J. Differential involvement of 5-HT(1B/1D) and 5-HT6 receptors in cognitive and non-cognitive symptoms in Alzheimer's disease. Neuropsychopharmacology 2004, 29:410-416.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 410-416
    • Garcia-Alloza, M.1    Hirst, W.D.2    Chen, C.P.3    Lasheras, B.4    Francis, P.T.5    Ramirez, M.J.6
  • 43
    • 0037096360 scopus 로고    scopus 로고
    • D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase
    • Gerfen C.R., Miyachi S., Paletzki R., Brown P. D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase. J. Neurosci. 2002, 22(12):5042-5054.
    • (2002) J. Neurosci. , vol.22 , Issue.12 , pp. 5042-5054
    • Gerfen, C.R.1    Miyachi, S.2    Paletzki, R.3    Brown, P.4
  • 44
    • 0033622132 scopus 로고    scopus 로고
    • Distinct roles for Galpha(i)2 and Gbetagamma in signaling to DNA synthesis and Galpha(i)3 in cellular transformation by dopamine D2S receptor activation in BALB/c 3T3 cells
    • Ghahremani M.H., Forget C., Albert P.R. Distinct roles for Galpha(i)2 and Gbetagamma in signaling to DNA synthesis and Galpha(i)3 in cellular transformation by dopamine D2S receptor activation in BALB/c 3T3 cells. Mol. Cell. Biol. 2000, 20:1497-1506.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 1497-1506
    • Ghahremani, M.H.1    Forget, C.2    Albert, P.R.3
  • 45
    • 69449089052 scopus 로고    scopus 로고
    • Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease
    • Gong Y., Lippa C.F., Zhu J., Lin Q., Rosso A.L. Disruption of glutamate receptors at Shank-postsynaptic platform in Alzheimer's disease. Brain Res. 2009, 1292:191-198.
    • (2009) Brain Res. , vol.1292 , pp. 191-198
    • Gong, Y.1    Lippa, C.F.2    Zhu, J.3    Lin, Q.4    Rosso, A.L.5
  • 46
    • 77950593768 scopus 로고    scopus 로고
    • Alpha7 nAChR-mediated activation of MAP kinase pathways in PC12 cells
    • Gubbins E.J., Gopalakrishnan M., Li J. Alpha7 nAChR-mediated activation of MAP kinase pathways in PC12 cells. Brain Res. 2010, 1328:1-11.
    • (2010) Brain Res. , vol.1328 , pp. 1-11
    • Gubbins, E.J.1    Gopalakrishnan, M.2    Li, J.3
  • 47
    • 9744226444 scopus 로고    scopus 로고
    • Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases
    • Gubellini P., Pisani A., Centonze D., Bernardi G., Calabresi P. Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases. Prog. Neurobiol. 2004, 74(5):271-300.
    • (2004) Prog. Neurobiol. , vol.74 , Issue.5 , pp. 271-300
    • Gubellini, P.1    Pisani, A.2    Centonze, D.3    Bernardi, G.4    Calabresi, P.5
  • 49
    • 78650415348 scopus 로고    scopus 로고
    • Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography
    • Gulyás B., Pavlova E., Kása P., Gulya K., Bakota L. Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography. Neurochem. Int. 2011, 58(1):60-68.
    • (2011) Neurochem. Int. , vol.58 , Issue.1 , pp. 60-68
    • Gulyás, B.1    Pavlova, E.2    Kása, P.3    Gulya, K.4    Bakota, L.5
  • 50
    • 2542431131 scopus 로고    scopus 로고
    • Rationale for and use of NMDA receptor antagonists in Parkinson's disease
    • Hallett P.J., Standaert D.G. Rationale for and use of NMDA receptor antagonists in Parkinson's disease. Pharmacol. Ther. 2004, 102:155-174.
    • (2004) Pharmacol. Ther. , vol.102 , pp. 155-174
    • Hallett, P.J.1    Standaert, D.G.2
  • 51
    • 33646824867 scopus 로고    scopus 로고
    • Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking
    • Hallett P.J., Spoelgen R., Hyman B.T., Standaert D.G., Dunah A.W. Dopamine D1 activation potentiates striatal NMDA receptors by tyrosine phosphorylation-dependent subunit trafficking. J. Neurosci. 2006, 26(17):4690-4700.
    • (2006) J. Neurosci. , vol.26 , Issue.17 , pp. 4690-4700
    • Hallett, P.J.1    Spoelgen, R.2    Hyman, B.T.3    Standaert, D.G.4    Dunah, A.W.5
  • 52
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
    • Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297:353-356.
    • (2002) Science , vol.297 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 53
    • 39049133870 scopus 로고    scopus 로고
    • Neonatal inflammation produces selective behavioural deficits and alters N-methyl-d-aspartate receptor subunit mRNA in the adult rat brain
    • Harré E.M., Galic M.A., Mouihate A., Noorbakhsh F., Pittman Q.J. Neonatal inflammation produces selective behavioural deficits and alters N-methyl-d-aspartate receptor subunit mRNA in the adult rat brain. Eur. J. Neurosci. 2008, 27(3):644-653.
    • (2008) Eur. J. Neurosci. , vol.27 , Issue.3 , pp. 644-653
    • Harré, E.M.1    Galic, M.A.2    Mouihate, A.3    Noorbakhsh, F.4    Pittman, Q.J.5
  • 57
    • 77249153190 scopus 로고    scopus 로고
    • Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease
    • Hernandez C.M., Kayed R., Zheng H., Sweatt J.D., Dineley K.T. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. J. Neurosci. 2010, 30:2442-2453.
    • (2010) J. Neurosci. , vol.30 , pp. 2442-2453
    • Hernandez, C.M.1    Kayed, R.2    Zheng, H.3    Sweatt, J.D.4    Dineley, K.T.5
  • 59
    • 0030961840 scopus 로고    scopus 로고
    • 5-HT receptor classification and nomenclature: towards a harmonization with the human genome
    • Hoyer D., Martin G. 5-HT receptor classification and nomenclature: towards a harmonization with the human genome. Neuropharmacology 1997, 36(4-5):419-428.
    • (1997) Neuropharmacology , vol.36 , Issue.4-5 , pp. 419-428
    • Hoyer, D.1    Martin, G.2
  • 60
    • 0036941840 scopus 로고    scopus 로고
    • Nicotinic regulation of CREB activation in hippocampal neurons by glutamatergic and nonglutamatergic pathways
    • Hu M., Liu Q.S., Chang K.T., Berg D.K. Nicotinic regulation of CREB activation in hippocampal neurons by glutamatergic and nonglutamatergic pathways. Mol. Cell. Neurosci. 2002, 21:616-625.
    • (2002) Mol. Cell. Neurosci. , vol.21 , pp. 616-625
    • Hu, M.1    Liu, Q.S.2    Chang, K.T.3    Berg, D.K.4
  • 61
    • 80052834174 scopus 로고    scopus 로고
    • The serotonergic system in Parkinson's disease
    • Huot P., Fox S.H., Brotchie J.M. The serotonergic system in Parkinson's disease. Prog. Neurobiol. 2011, 95(2):163-212.
    • (2011) Prog. Neurobiol. , vol.95 , Issue.2 , pp. 163-212
    • Huot, P.1    Fox, S.H.2    Brotchie, J.M.3
  • 62
    • 33746374720 scopus 로고    scopus 로고
    • What has been learnt from study of dopamine receptors in Parkinson's disease?
    • Hurley M.J., Jenner P. What has been learnt from study of dopamine receptors in Parkinson's disease?. Pharmacol. Ther. 2006, 111:715-728.
    • (2006) Pharmacol. Ther. , vol.111 , pp. 715-728
    • Hurley, M.J.1    Jenner, P.2
  • 63
    • 4143117789 scopus 로고    scopus 로고
    • Differential expression of N-methyl-d-aspartate receptor NR2 isoforms in Alzheimer's disease
    • Hynd M.R., Scott H.L., Dodd P.R. Differential expression of N-methyl-d-aspartate receptor NR2 isoforms in Alzheimer's disease. J. Neurochem. 2004, 90:913-919.
    • (2004) J. Neurochem. , vol.90 , pp. 913-919
    • Hynd, M.R.1    Scott, H.L.2    Dodd, P.R.3
  • 64
    • 0032710970 scopus 로고    scopus 로고
    • Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease
    • Ikonomovic M.D., Mizukami K., Warde D., Sheffield R., Hamilton R., Wenthold R.J., Armstrong D.M. Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease. Exp. Neurol. 1999, 160:194-204.
    • (1999) Exp. Neurol. , vol.160 , pp. 194-204
    • Ikonomovic, M.D.1    Mizukami, K.2    Warde, D.3    Sheffield, R.4    Hamilton, R.5    Wenthold, R.J.6    Armstrong, D.M.7
  • 65
    • 0033136259 scopus 로고    scopus 로고
    • Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity
    • Impey S., Obrietan K., Storm D.R. Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity. Neuron 1999, 23:11-14.
    • (1999) Neuron , vol.23 , pp. 11-14
    • Impey, S.1    Obrietan, K.2    Storm, D.R.3
  • 67
    • 11344258408 scopus 로고    scopus 로고
    • Cellular and synaptic distribution of NR2A and NR2B in macaque monkey and rat hippocampus as visualized with subunit-specific monoclonal antibodies
    • Janssen W.G., Vissavajjhala P., Andrews G., Moran T., Hof P.R., Morrison J.H. Cellular and synaptic distribution of NR2A and NR2B in macaque monkey and rat hippocampus as visualized with subunit-specific monoclonal antibodies. Exp. Neurol. 2005, 191(Suppl. 1):S28-S44.
    • (2005) Exp. Neurol. , vol.191 , Issue.SUPPL. 1
    • Janssen, W.G.1    Vissavajjhala, P.2    Andrews, G.3    Moran, T.4    Hof, P.R.5    Morrison, J.H.6
  • 68
    • 0034879826 scopus 로고    scopus 로고
    • Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity
    • Ji D., Lape R., Dani J.A. Timing and location of nicotinic activity enhances or depresses hippocampal synaptic plasticity. Neuron 2001, 31:131-141.
    • (2001) Neuron , vol.31 , pp. 131-141
    • Ji, D.1    Lape, R.2    Dani, J.A.3
  • 69
    • 33745949221 scopus 로고    scopus 로고
    • Panic-prone state induced in rats with GABA dysfunction in the dorsomedial hypothalamus is mediated by NMDA receptors
    • Johnson P.L., Shekhar A. Panic-prone state induced in rats with GABA dysfunction in the dorsomedial hypothalamus is mediated by NMDA receptors. J. Neurosci. 2006, 26(26):7093-7104.
    • (2006) J. Neurosci. , vol.26 , Issue.26 , pp. 7093-7104
    • Johnson, P.L.1    Shekhar, A.2
  • 70
    • 55249118679 scopus 로고    scopus 로고
    • Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats
    • Jones C.K., Brady A.E., Davis A.A., Xiang Z., Bubser M., et al. Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats. J. Neurosci. 2008, 28(41):10422-10433.
    • (2008) J. Neurosci. , vol.28 , Issue.41 , pp. 10422-10433
    • Jones, C.K.1    Brady, A.E.2    Davis, A.A.3    Xiang, Z.4    Bubser, M.5
  • 73
    • 0024853728 scopus 로고
    • Increased alpha 2- and beta 2-adrenergic receptors in cerebral microvessels in Alzheimer disease
    • Kalaria R.N., Harik S.I. Increased alpha 2- and beta 2-adrenergic receptors in cerebral microvessels in Alzheimer disease. Neurosci. Lett. 1989, 106:233-238.
    • (1989) Neurosci. Lett. , vol.106 , pp. 233-238
    • Kalaria, R.N.1    Harik, S.I.2
  • 74
    • 0026069017 scopus 로고
    • Adrenergic receptors in aging and Alzheimer's disease: decreased alpha 2-receptors demonstrated by [3H]p-aminoclonidine binding in prefrontal cortex
    • Kalaria R.N., Andorn A.C. Adrenergic receptors in aging and Alzheimer's disease: decreased alpha 2-receptors demonstrated by [3H]p-aminoclonidine binding in prefrontal cortex. Neurobiol. Aging 1991, 12:131-136.
    • (1991) Neurobiol. Aging , vol.12 , pp. 131-136
    • Kalaria, R.N.1    Andorn, A.C.2
  • 75
    • 0024780578 scopus 로고
    • Alterations in adrenergic receptors of frontal cortex and cerebral microvessels in Alzheimer's disease and aging
    • Kalaria R.N., Andorn A.C., Harik S.I. Alterations in adrenergic receptors of frontal cortex and cerebral microvessels in Alzheimer's disease and aging. Prog. Clin. Biol. Res. 1989, 317:367-374.
    • (1989) Prog. Clin. Biol. Res. , vol.317 , pp. 367-374
    • Kalaria, R.N.1    Andorn, A.C.2    Harik, S.I.3
  • 76
    • 0024445028 scopus 로고
    • Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus
    • Kalaria R.N., Andorn A.C., Tabaton M., Whitehouse P.J., Harik S.I., Unnerstall J.R. Adrenergic receptors in aging and Alzheimer's disease: increased beta 2-receptors in prefrontal cortex and hippocampus. J. Neurochem. 1989, 53:1772-1781.
    • (1989) J. Neurochem. , vol.53 , pp. 1772-1781
    • Kalaria, R.N.1    Andorn, A.C.2    Tabaton, M.3    Whitehouse, P.J.4    Harik, S.I.5    Unnerstall, J.R.6
  • 77
    • 0018766317 scopus 로고
    • Acetylcholine receptors (author's transl.)
    • Kato G., Agid Y. Acetylcholine receptors (author's transl.). Nouv. Presse Med. 1979, 8:2407-2411.
    • (1979) Nouv. Presse Med. , vol.8 , pp. 2407-2411
    • Kato, G.1    Agid, Y.2
  • 78
    • 0033854704 scopus 로고    scopus 로고
    • PET shows that striatal dopamine D1 and D2 receptors are differentially affected in AD
    • Kemppainen N., Ruottinen H., Nagren K., Rinne J.O. PET shows that striatal dopamine D1 and D2 receptors are differentially affected in AD. Neurology 2000, 55:205-209.
    • (2000) Neurology , vol.55 , pp. 205-209
    • Kemppainen, N.1    Ruottinen, H.2    Nagren, K.3    Rinne, J.O.4
  • 81
    • 77951653236 scopus 로고    scopus 로고
    • Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61
    • Kurup P., Zhang Y., Xu J., Venkitaramani D.V., Haroutunian V., Greengard P., Nairn A.C., Lombroso P.J. Abeta-mediated NMDA receptor endocytosis in Alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61. J. Neurosci. 2010, 30:5948-5957.
    • (2010) J. Neurosci. , vol.30 , pp. 5948-5957
    • Kurup, P.1    Zhang, Y.2    Xu, J.3    Venkitaramani, D.V.4    Haroutunian, V.5    Greengard, P.6    Nairn, A.C.7    Lombroso, P.J.8
  • 82
    • 0037651151 scopus 로고    scopus 로고
    • Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease
    • Lai M.K., Tsang S.W., Francis P.T., Esiri M.M., Keene J., Hope T., Chen C.P. Reduced serotonin 5-HT1A receptor binding in the temporal cortex correlates with aggressive behavior in Alzheimer disease. Brain Res. 2003, 974:82-87.
    • (2003) Brain Res. , vol.974 , pp. 82-87
    • Lai, M.K.1    Tsang, S.W.2    Francis, P.T.3    Esiri, M.M.4    Keene, J.5    Hope, T.6    Chen, C.P.7
  • 84
    • 0038466229 scopus 로고    scopus 로고
    • [3H]GR113808 binding to serotonin 5-HT(4) receptors in the postmortem neocortex of Alzheimer disease: a clinicopathological study
    • Lai M.K., Tsang S.W., Francis P.T., Esiri M.M., Hope T., Lai O.F., Spence I., Chen C.P. [3H]GR113808 binding to serotonin 5-HT(4) receptors in the postmortem neocortex of Alzheimer disease: a clinicopathological study. J. Neural Transm. 2003, 110:779-788.
    • (2003) J. Neural Transm. , vol.110 , pp. 779-788
    • Lai, M.K.1    Tsang, S.W.2    Francis, P.T.3    Esiri, M.M.4    Hope, T.5    Lai, O.F.6    Spence, I.7    Chen, C.P.8
  • 85
    • 18744402189 scopus 로고    scopus 로고
    • Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease
    • Lai M.K., Tsang S.W., Alder J.T., Keene J., Hope T., Esiri M.M., Francis P.T., Chen C.P. Loss of serotonin 5-HT2A receptors in the postmortem temporal cortex correlates with rate of cognitive decline in Alzheimer's disease. Psychopharmacology (Berlin) 2005, 179:673-677.
    • (2005) Psychopharmacology (Berlin) , vol.179 , pp. 673-677
    • Lai, M.K.1    Tsang, S.W.2    Alder, J.T.3    Keene, J.4    Hope, T.5    Esiri, M.M.6    Francis, P.T.7    Chen, C.P.8
  • 87
    • 73449142822 scopus 로고    scopus 로고
    • Alterations in 5-HT2A receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats
    • Li Y., Huang X.F., Deng C., Meyer B., Wu A., Yu Y., Ying W., Yang G.Y., Yenari M.A., Wang Q. Alterations in 5-HT2A receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats. Synapse 2010, 64(3):224-230.
    • (2010) Synapse , vol.64 , Issue.3 , pp. 224-230
    • Li, Y.1    Huang, X.F.2    Deng, C.3    Meyer, B.4    Wu, A.5    Yu, Y.6    Ying, W.7    Yang, G.Y.8    Yenari, M.A.9    Wang, Q.10
  • 88
    • 79951567728 scopus 로고    scopus 로고
    • Functional interactions of fibrillar and oligomeric amyloid-beta with alpha7 nicotinic receptors in Alzheimer's disease
    • Lilja A.M., Porras O., Storelli E., Nordberg A., Marutle A. Functional interactions of fibrillar and oligomeric amyloid-beta with alpha7 nicotinic receptors in Alzheimer's disease. J. Alzheimers Dis. 2011, 23:335-347.
    • (2011) J. Alzheimers Dis. , vol.23 , pp. 335-347
    • Lilja, A.M.1    Porras, O.2    Storelli, E.3    Nordberg, A.4    Marutle, A.5
  • 89
    • 72049120979 scopus 로고    scopus 로고
    • Genetic variation in N-methyl-d-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease
    • Liu H.P., Lin W.Y., Liu S.H., Wang W.F., Tsai C.H., Wu B.T., Wang C.K., Tsai F.J. Genetic variation in N-methyl-d-aspartate receptor subunit NR3A but not NR3B influences susceptibility to Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 2009, 28:521-527.
    • (2009) Dement. Geriatr. Cogn. Disord. , vol.28 , pp. 521-527
    • Liu, H.P.1    Lin, W.Y.2    Liu, S.H.3    Wang, W.F.4    Tsai, C.H.5    Wu, B.T.6    Wang, C.K.7    Tsai, F.J.8
  • 90
    • 52949099850 scopus 로고    scopus 로고
    • Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat
    • Marcos B., Chuang T.T., Gil-Bea F.J., Ramirez M.J. Effects of 5-HT6 receptor antagonism and cholinesterase inhibition in models of cognitive impairment in the rat. Br. J. Pharmacol. 2008, 155:434-440.
    • (2008) Br. J. Pharmacol. , vol.155 , pp. 434-440
    • Marcos, B.1    Chuang, T.T.2    Gil-Bea, F.J.3    Ramirez, M.J.4
  • 91
    • 0034887218 scopus 로고    scopus 로고
    • Choline acetytransferase activity and striatal dopamine receptors in Parkinson's disease in relation to cognitive impairment
    • Mattila P.M., Roytta M., Lonnberg P., Marjamaki P., Helenius H., Rinne J.O. Choline acetytransferase activity and striatal dopamine receptors in Parkinson's disease in relation to cognitive impairment. Acta Neuropathol. 2001, 102:160-166.
    • (2001) Acta Neuropathol. , vol.102 , pp. 160-166
    • Mattila, P.M.1    Roytta, M.2    Lonnberg, P.3    Marjamaki, P.4    Helenius, H.5    Rinne, J.O.6
  • 92
    • 0026773764 scopus 로고
    • Decreased density of presynaptic alpha 2-adrenoceptors in postmortem brains of patients with Alzheimer's disease
    • Meana J.J., Barturen F., Garro M.A., Garcia-Sevilla J.A., Fontan A., Zarranz J.J. Decreased density of presynaptic alpha 2-adrenoceptors in postmortem brains of patients with Alzheimer's disease. J. Neurochem. 1992, 58:1896-1904.
    • (1992) J. Neurochem. , vol.58 , pp. 1896-1904
    • Meana, J.J.1    Barturen, F.2    Garro, M.A.3    Garcia-Sevilla, J.A.4    Fontan, A.5    Zarranz, J.J.6
  • 94
    • 0032861536 scopus 로고    scopus 로고
    • Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease
    • Mehta M.A., Sahakian B.J., McKenna P.J., Robbins T.W. Systemic sulpiride in young adult volunteers simulates the profile of cognitive deficits in Parkinson's disease. Psychopharmacology (Berlin) 1999, 146:162-174.
    • (1999) Psychopharmacology (Berlin) , vol.146 , pp. 162-174
    • Mehta, M.A.1    Sahakian, B.J.2    McKenna, P.J.3    Robbins, T.W.4
  • 95
    • 0032588309 scopus 로고    scopus 로고
    • 5-HT1A receptors modulate the consolidation of learning in normal and cognitively impaired rats
    • Meneses A., Hong E. 5-HT1A receptors modulate the consolidation of learning in normal and cognitively impaired rats. Neurobiol. Learn. Mem. 1999, 71:207-218.
    • (1999) Neurobiol. Learn. Mem. , vol.71 , pp. 207-218
    • Meneses, A.1    Hong, E.2
  • 96
    • 0032989883 scopus 로고    scopus 로고
    • NMDA NR1 subunit mRNA and glutamate NMDA-sensitive binding are differentially affected in the striatum and pre-frontal cortex of Parkinson's disease patients
    • Meoni P., Bunnemann B.H., Kingsbury A.E., Trist D.G., Bowery N.G. NMDA NR1 subunit mRNA and glutamate NMDA-sensitive binding are differentially affected in the striatum and pre-frontal cortex of Parkinson's disease patients. Neuropharmacology 1999, 38:625-633.
    • (1999) Neuropharmacology , vol.38 , pp. 625-633
    • Meoni, P.1    Bunnemann, B.H.2    Kingsbury, A.E.3    Trist, D.G.4    Bowery, N.G.5
  • 99
    • 1642538398 scopus 로고    scopus 로고
    • Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology
    • Mishizen-Eberz A.J., Rissman R.A., Carter T.L., Ikonomovic M.D., Wolfe B.B., Armstrong D.M. Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology. Neurobiol. Dis. 2004, 15:80-92.
    • (2004) Neurobiol. Dis. , vol.15 , pp. 80-92
    • Mishizen-Eberz, A.J.1    Rissman, R.A.2    Carter, T.L.3    Ikonomovic, M.D.4    Wolfe, B.B.5    Armstrong, D.M.6
  • 100
    • 28044437798 scopus 로고    scopus 로고
    • 5-HT6 receptors: a novel target for cognitive enhancement
    • Mitchell E.S., Neumaier J.F. 5-HT6 receptors: a novel target for cognitive enhancement. Pharmacol. Ther. 2005, 108:320-333.
    • (2005) Pharmacol. Ther. , vol.108 , pp. 320-333
    • Mitchell, E.S.1    Neumaier, J.F.2
  • 102
    • 33748081791 scopus 로고    scopus 로고
    • The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo
    • Miwa J.M., Stevens T.R., King S.L., Caldarone B.J., Ibanez-Tallon I., et al. The prototoxin lynx1 acts on nicotinic acetylcholine receptors to balance neuronal activity and survival in vivo. Neuron 2006, 51(5):587-600.
    • (2006) Neuron , vol.51 , Issue.5 , pp. 587-600
    • Miwa, J.M.1    Stevens, T.R.2    King, S.L.3    Caldarone, B.J.4    Ibanez-Tallon, I.5
  • 103
    • 0027174496 scopus 로고
    • Autoradiographic study on dopamine uptake sites and their correlation with dopamine levels and their striata from patients with Parkinson disease. Alzheimer disease, and neurologically normal controls
    • Mizukawa K., McGeer E.G., McGeer P.L. Autoradiographic study on dopamine uptake sites and their correlation with dopamine levels and their striata from patients with Parkinson disease. Alzheimer disease, and neurologically normal controls. Mol. Chem. Neuropathol. 1993, 18:133-144.
    • (1993) Mol. Chem. Neuropathol. , vol.18 , pp. 133-144
    • Mizukawa, K.1    McGeer, E.G.2    McGeer, P.L.3
  • 105
    • 0344875505 scopus 로고    scopus 로고
    • Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor
    • Nair V.D., Sealfon S.C. Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. J. Biol. Chem. 2003, 278:47053-47061.
    • (2003) J. Biol. Chem. , vol.278 , pp. 47053-47061
    • Nair, V.D.1    Sealfon, S.C.2
  • 106
  • 107
    • 0036062938 scopus 로고    scopus 로고
    • Dopamine and the regulation of cognition and attention
    • Nieoullon A. Dopamine and the regulation of cognition and attention. Prog. Neurobiol. 2002, 67:53-83.
    • (2002) Prog. Neurobiol. , vol.67 , pp. 53-83
    • Nieoullon, A.1
  • 110
    • 0033571938 scopus 로고    scopus 로고
    • Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases
    • Otani S., Auclair N., Desce J.M., Roisin M.P., Crepel F. Dopamine receptors and groups I and II mGluRs cooperate for long-term depression induction in rat prefrontal cortex through converging postsynaptic activation of MAP kinases. J. Neurosci. 1999, 19:9788-9802.
    • (1999) J. Neurosci. , vol.19 , pp. 9788-9802
    • Otani, S.1    Auclair, N.2    Desce, J.M.3    Roisin, M.P.4    Crepel, F.5
  • 111
    • 0036166948 scopus 로고    scopus 로고
    • The mRNA of the NR1 subtype of glutamate receptor in Alzheimer's disease
    • Panegyres P.K., Zafiris-Toufexis K., Kakulas B.A. The mRNA of the NR1 subtype of glutamate receptor in Alzheimer's disease. J. Neural Transm. 2002, 109:77-89.
    • (2002) J. Neural Transm. , vol.109 , pp. 77-89
    • Panegyres, P.K.1    Zafiris-Toufexis, K.2    Kakulas, B.A.3
  • 112
    • 33846920665 scopus 로고    scopus 로고
    • NMDA receptor subunits: function and pharmacology
    • Paoletti P., Neyton J. NMDA receptor subunits: function and pharmacology. Curr. Opin. Pharmacol. 2007, 7:39-47.
    • (2007) Curr. Opin. Pharmacol. , vol.7 , pp. 39-47
    • Paoletti, P.1    Neyton, J.2
  • 113
    • 0026682941 scopus 로고
    • Loss of high-affinity alpha 2-adrenoceptors in Alzheimer's disease: an autoradiographic study in frontal cortex and hippocampus
    • Pascual J., Grijalba B., Garcia-Sevilla J.A., Zarranz J.J., Pazos A. Loss of high-affinity alpha 2-adrenoceptors in Alzheimer's disease: an autoradiographic study in frontal cortex and hippocampus. Neurosci. Lett. 1992, 142:36-40.
    • (1992) Neurosci. Lett. , vol.142 , pp. 36-40
    • Pascual, J.1    Grijalba, B.2    Garcia-Sevilla, J.A.3    Zarranz, J.J.4    Pazos, A.5
  • 114
    • 79955739415 scopus 로고    scopus 로고
    • Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage
    • Pascual M., Baliño P., Alfonso-Loeches S., Aragón C.M., Guerri C. Impact of TLR4 on behavioral and cognitive dysfunctions associated with alcohol-induced neuroinflammatory damage. Brain Behav. Immun. 2011, 25(Suppl. 1):S80-S91.
    • (2011) Brain Behav. Immun. , vol.25 , Issue.SUPPL. 1
    • Pascual, M.1    Baliño, P.2    Alfonso-Loeches, S.3    Aragón, C.M.4    Guerri, C.5
  • 115
    • 0033964077 scopus 로고    scopus 로고
    • Neuronal nicotinic receptors in the human brain
    • Paterson D., Nordberg A. Neuronal nicotinic receptors in the human brain. Prog. Neurobiol. 2000, 61(1):75-111.
    • (2000) Prog. Neurobiol. , vol.61 , Issue.1 , pp. 75-111
    • Paterson, D.1    Nordberg, A.2
  • 116
    • 22044457309 scopus 로고    scopus 로고
    • Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task
    • Perez-García G., Meneses A. Oral administration of the 5-HT6 receptor antagonists SB-357134 and SB-399885 improves memory formation in an autoshaping learning task. Pharmacol. Biochem. Behav. 2005, 81(3):673-682.
    • (2005) Pharmacol. Biochem. Behav. , vol.81 , Issue.3 , pp. 673-682
    • Perez-García, G.1    Meneses, A.2
  • 119
    • 0038523950 scopus 로고    scopus 로고
    • Endogenous dopamine release after pharmacological challenges in Parkinson's disease
    • Piccini P., Pavese N., Brooks D.J. Endogenous dopamine release after pharmacological challenges in Parkinson's disease. Ann. Neurol. 2003, 53(5):647-653.
    • (2003) Ann. Neurol. , vol.53 , Issue.5 , pp. 647-653
    • Piccini, P.1    Pavese, N.2    Brooks, D.J.3
  • 122
    • 0029834869 scopus 로고    scopus 로고
    • Reduced striatal dopamine receptors in Alzheimer's disease: single photon emission tomography study with the D2 tracer [123I]-IBZM
    • Pizzolato G., Chierichetti F., Fabbri M., Cagnin A., Dam M., Ferlin G., Battistin L. Reduced striatal dopamine receptors in Alzheimer's disease: single photon emission tomography study with the D2 tracer [123I]-IBZM. Neurology 1996, 47:1065-1068.
    • (1996) Neurology , vol.47 , pp. 1065-1068
    • Pizzolato, G.1    Chierichetti, F.2    Fabbri, M.3    Cagnin, A.4    Dam, M.5    Ferlin, G.6    Battistin, L.7
  • 123
    • 54049120959 scopus 로고    scopus 로고
    • Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: an in vivo 11C-raclopride PET study
    • Politis M., Piccini P., Pavese N., Koh S.B., Brooks D.J. Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: an in vivo 11C-raclopride PET study. Exp. Neurol. 2008, 214:112-116.
    • (2008) Exp. Neurol. , vol.214 , pp. 112-116
    • Politis, M.1    Piccini, P.2    Pavese, N.3    Koh, S.B.4    Brooks, D.J.5
  • 124
    • 77954536179 scopus 로고    scopus 로고
    • 5-HT1A receptor-regulated signal transduction pathways in brain
    • Polter A.M., Li X. 5-HT1A receptor-regulated signal transduction pathways in brain. Cell. Signal. 2010, 22(10):1406-1412.
    • (2010) Cell. Signal. , vol.22 , Issue.10 , pp. 1406-1412
    • Polter, A.M.1    Li, X.2
  • 125
    • 77952712188 scopus 로고    scopus 로고
    • The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner
    • Poulin B., Butcher A., McWilliams P., Bourgognon J.M., Pawlak R., et al. The M3-muscarinic receptor regulates learning and memory in a receptor phosphorylation/arrestin-dependent manner. Proc. Natl. Acad. Sci. U. S. A. 2010, 107(20):9440-9445.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , Issue.20 , pp. 9440-9445
    • Poulin, B.1    Butcher, A.2    McWilliams, P.3    Bourgognon, J.M.4    Pawlak, R.5
  • 126
    • 0036343122 scopus 로고    scopus 로고
    • Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders
    • Pralong E., Magistretti P., Stoop R. Cellular perspectives on the glutamate-monoamine interactions in limbic lobe structures and their relevance for some psychiatric disorders. Prog. Neurobiol. 2002, 67(3):173-202.
    • (2002) Prog. Neurobiol. , vol.67 , Issue.3 , pp. 173-202
    • Pralong, E.1    Magistretti, P.2    Stoop, R.3
  • 127
    • 79953054837 scopus 로고    scopus 로고
    • Post-synaptic scaffolding protein interactions with glutamate receptors in synaptic dysfunction and Alzheimer's disease
    • Proctor D.T., Coulson E.J., Dodd P.R. Post-synaptic scaffolding protein interactions with glutamate receptors in synaptic dysfunction and Alzheimer's disease. Prog. Neurobiol. 2011, 93(4):509-521.
    • (2011) Prog. Neurobiol. , vol.93 , Issue.4 , pp. 509-521
    • Proctor, D.T.1    Coulson, E.J.2    Dodd, P.R.3
  • 128
    • 62149141359 scopus 로고    scopus 로고
    • Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease
    • Reeves S., Brown R., Howard R., Grasby P. Increased striatal dopamine (D2/D3) receptor availability and delusions in Alzheimer disease. Neurology 2009, 72:528-534.
    • (2009) Neurology , vol.72 , pp. 528-534
    • Reeves, S.1    Brown, R.2    Howard, R.3    Grasby, P.4
  • 129
    • 73049116696 scopus 로고    scopus 로고
    • The dopaminergic basis of cognitive and motor performance in Alzheimer's disease
    • Reeves S., Mehta M., Howard R., Grasby P., Brown R. The dopaminergic basis of cognitive and motor performance in Alzheimer's disease. Neurobiol. Dis. 2010, 37:477-482.
    • (2010) Neurobiol. Dis. , vol.37 , pp. 477-482
    • Reeves, S.1    Mehta, M.2    Howard, R.3    Grasby, P.4    Brown, R.5
  • 130
    • 25844471545 scopus 로고    scopus 로고
    • A positron emission tomography (PET) investigation of the role of striatal dopamine (D2) receptor availability in spatial cognition
    • Reeves S.J., Grasby P.M., Howard R.J., Bantick R.A., Asselin M.C., Mehta M.A. A positron emission tomography (PET) investigation of the role of striatal dopamine (D2) receptor availability in spatial cognition. Neuroimage 2005, 28:216-226.
    • (2005) Neuroimage , vol.28 , pp. 216-226
    • Reeves, S.J.1    Grasby, P.M.2    Howard, R.J.3    Bantick, R.A.4    Asselin, M.C.5    Mehta, M.A.6
  • 131
    • 77953603178 scopus 로고    scopus 로고
    • Effects of dopamine agonists on neuropsychiatric symptoms of Parkinson's disease
    • Rektorová I. Effects of dopamine agonists on neuropsychiatric symptoms of Parkinson's disease. Neurodegener. Dis. 2010, 7(1-3):206-209.
    • (2010) Neurodegener. Dis. , vol.7 , Issue.1-3 , pp. 206-209
    • Rektorová, I.1
  • 133
    • 80051759972 scopus 로고    scopus 로고
    • Dopamine D1 receptor associations within and between dopaminergic pathways in younger and elderly adults: links to cognitive performance
    • Rieckmann A., Karlsson S., Karlsson P., Brehmer Y., Fischer H., Farde L., Nyberg L., Bäckman L. Dopamine D1 receptor associations within and between dopaminergic pathways in younger and elderly adults: links to cognitive performance. Cereb. Cortex 2011, 21(9):2023-2032.
    • (2011) Cereb. Cortex , vol.21 , Issue.9 , pp. 2023-2032
    • Rieckmann, A.1    Karlsson, S.2    Karlsson, P.3    Brehmer, Y.4    Fischer, H.5    Farde, L.6    Nyberg, L.7    Bäckman, L.8
  • 134
    • 0025803731 scopus 로고
    • A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease
    • Rinne J.O., Myllykyla T., Lonnberg P., Marjamaki P. A postmortem study of brain nicotinic receptors in Parkinson's and Alzheimer's disease. Brain Res. 1991, 547:167-170.
    • (1991) Brain Res. , vol.547 , pp. 167-170
    • Rinne, J.O.1    Myllykyla, T.2    Lonnberg, P.3    Marjamaki, P.4
  • 136
    • 77949360999 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonists as potential therapeutics for cognitive impairment
    • Rosse G., Schaffhauser H. 5-HT6 receptor antagonists as potential therapeutics for cognitive impairment. Curr. Top. Med. Chem. 2010, 10:207-221.
    • (2010) Curr. Top. Med. Chem. , vol.10 , pp. 207-221
    • Rosse, G.1    Schaffhauser, H.2
  • 138
    • 0030855803 scopus 로고    scopus 로고
    • Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients
    • Russo-Neustadt A., Cotman C.W. Adrenergic receptors in Alzheimer's disease brain: selective increases in the cerebella of aggressive patients. J. Neurosci. 1997, 17:5573-5580.
    • (1997) J. Neurosci. , vol.17 , pp. 5573-5580
    • Russo-Neustadt, A.1    Cotman, C.W.2
  • 139
    • 33845535334 scopus 로고    scopus 로고
    • Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging
    • Sabbagh M.N., Shah F., Reid R.T., Sue L., Connor D.J., Peterson L.K., Beach T.G. Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging. Arch. Neurol. 2006, 63:1771-1776.
    • (2006) Arch. Neurol. , vol.63 , pp. 1771-1776
    • Sabbagh, M.N.1    Shah, F.2    Reid, R.T.3    Sue, L.4    Connor, D.J.5    Peterson, L.K.6    Beach, T.G.7
  • 141
    • 0033800339 scopus 로고    scopus 로고
    • The role of D1-dopamine receptors in working memory-guided movements mediated by frontal cortical areas
    • Sawaguchi T. The role of D1-dopamine receptors in working memory-guided movements mediated by frontal cortical areas. Parkinsonism Relat. Disord. 2000, 7(1):9-19.
    • (2000) Parkinsonism Relat. Disord. , vol.7 , Issue.1 , pp. 9-19
    • Sawaguchi, T.1
  • 142
    • 44949221767 scopus 로고    scopus 로고
    • Cognitive deficits and striato-frontal dopamine release in Parkinson's disease
    • Sawamoto N., Piccini P., Hotton G., Pavese N., Thielemans K., Brooks D.J. Cognitive deficits and striato-frontal dopamine release in Parkinson's disease. Brain 2008, 131:1294-1302.
    • (2008) Brain , vol.131 , pp. 1294-1302
    • Sawamoto, N.1    Piccini, P.2    Hotton, G.3    Pavese, N.4    Thielemans, K.5    Brooks, D.J.6
  • 144
    • 34447118214 scopus 로고    scopus 로고
    • Aggressive behavior and neuroleptic medication are associated with increased number of alpha1-adrenoceptors in patients with Alzheimer disease
    • Sharp S.I., Ballard C.G., Chen C.P., Francis P.T. Aggressive behavior and neuroleptic medication are associated with increased number of alpha1-adrenoceptors in patients with Alzheimer disease. Am. J. Geriatr. Psychiatr. 2007, 15:435-437.
    • (2007) Am. J. Geriatr. Psychiatr. , vol.15 , pp. 435-437
    • Sharp, S.I.1    Ballard, C.G.2    Chen, C.P.3    Francis, P.T.4
  • 145
    • 67549109441 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system
    • Shen J.X., Yakel J.L. Nicotinic acetylcholine receptor-mediated calcium signaling in the nervous system. Acta Pharmacol. Sin. 2009, 30:673-680.
    • (2009) Acta Pharmacol. Sin. , vol.30 , pp. 673-680
    • Shen, J.X.1    Yakel, J.L.2
  • 146
    • 0022792901 scopus 로고
    • Biochemical characterization of alpha-adrenergic receptors in human brain and changes in Alzheimer-type dementia
    • Shimohama S., Taniguchi T., Fujiwara M., Kameyama M. Biochemical characterization of alpha-adrenergic receptors in human brain and changes in Alzheimer-type dementia. J. Neurochem. 1986, 47:1295-1301.
    • (1986) J. Neurochem. , vol.47 , pp. 1295-1301
    • Shimohama, S.1    Taniguchi, T.2    Fujiwara, M.3    Kameyama, M.4
  • 147
    • 0023475270 scopus 로고
    • Changes in beta-adrenergic receptor subtypes in Alzheimer-type dementia
    • Shimohama S., Taniguchi T., Fujiwara M., Kameyama M. Changes in beta-adrenergic receptor subtypes in Alzheimer-type dementia. J. Neurochem. 1987, 48:1215-1221.
    • (1987) J. Neurochem. , vol.48 , pp. 1215-1221
    • Shimohama, S.1    Taniguchi, T.2    Fujiwara, M.3    Kameyama, M.4
  • 149
    • 0035116342 scopus 로고    scopus 로고
    • Involvement of protein kinase C in the presynaptic nicotinic modulation of [(3)H]-dopamine release from rat striatal synaptosomes
    • Soliakov L., Wonnacott S. Involvement of protein kinase C in the presynaptic nicotinic modulation of [(3)H]-dopamine release from rat striatal synaptosomes. Br. J. Pharmacol. 2001, 132:785-791.
    • (2001) Br. J. Pharmacol. , vol.132 , pp. 785-791
    • Soliakov, L.1    Wonnacott, S.2
  • 151
    • 34548189417 scopus 로고    scopus 로고
    • Effect of buspirone, a serotonin1A partial agonist, on cognitive function in schizophrenia: a randomized, double-blind, placebo-controlled study
    • Sumiyoshi T., Park S., Jayathilake K., Roy A., Ertugrul A., Meltzer H.Y. Effect of buspirone, a serotonin1A partial agonist, on cognitive function in schizophrenia: a randomized, double-blind, placebo-controlled study. Schizophr. Res. 2007, 95(1-3):158-168.
    • (2007) Schizophr. Res. , vol.95 , Issue.1-3 , pp. 158-168
    • Sumiyoshi, T.1    Park, S.2    Jayathilake, K.3    Roy, A.4    Ertugrul, A.5    Meltzer, H.Y.6
  • 152
    • 78650663823 scopus 로고    scopus 로고
    • Environmental enrichment influences BDNF and NR1 levels in the hippocampus and restores cognitive impairment in chronic cerebral hypoperfused rats
    • Sun H., Zhang J., Zhang L., Liu H., Zhu H., Yang Y. Environmental enrichment influences BDNF and NR1 levels in the hippocampus and restores cognitive impairment in chronic cerebral hypoperfused rats. Curr. Neurovasc. Res. 2010, 7:268-280.
    • (2010) Curr. Neurovasc. Res. , vol.7 , pp. 268-280
    • Sun, H.1    Zhang, J.2    Zhang, L.3    Liu, H.4    Zhu, H.5    Yang, Y.6
  • 153
    • 75849136383 scopus 로고    scopus 로고
    • Different striatal D2-like receptor function in an early stage after unilateral striatal lesion and medial forebrain bundle lesion in rats
    • Sun W., Sugiyama K., Fang X., Yamaguchi H., Akamine S., Magata Y., Namba H. Different striatal D2-like receptor function in an early stage after unilateral striatal lesion and medial forebrain bundle lesion in rats. Brain Res. 2010, 1317:227-235.
    • (2010) Brain Res. , vol.1317 , pp. 227-235
    • Sun, W.1    Sugiyama, K.2    Fang, X.3    Yamaguchi, H.4    Akamine, S.5    Magata, Y.6    Namba, H.7
  • 154
    • 79955756487 scopus 로고    scopus 로고
    • Dynamic changes of striatal dopamine D2 receptor binding at later stages after unilateral lesions of the medial forebrain bundle in Parkinsonian rat models
    • Sun W., Sugiyama K., Asakawa T., Yamaguchi H., Akamine S., Ouchi Y., Magata Y., Namba H. Dynamic changes of striatal dopamine D2 receptor binding at later stages after unilateral lesions of the medial forebrain bundle in Parkinsonian rat models. Neurosci. Lett. 2011, 496(3):157-162.
    • (2011) Neurosci. Lett. , vol.496 , Issue.3 , pp. 157-162
    • Sun, W.1    Sugiyama, K.2    Asakawa, T.3    Yamaguchi, H.4    Akamine, S.5    Ouchi, Y.6    Magata, Y.7    Namba, H.8
  • 155
    • 32544460565 scopus 로고    scopus 로고
    • Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies
    • Szot P., White S.S., Greenup J.L., Leverenz J.B., Peskind E.R., Raskind M.A. Compensatory changes in the noradrenergic nervous system in the locus ceruleus and hippocampus of postmortem subjects with Alzheimer's disease and dementia with Lewy bodies. J. Neurosci. 2006, 26:467-478.
    • (2006) J. Neurosci. , vol.26 , pp. 467-478
    • Szot, P.1    White, S.S.2    Greenup, J.L.3    Leverenz, J.B.4    Peskind, E.R.5    Raskind, M.A.6
  • 158
    • 49149118550 scopus 로고    scopus 로고
    • Alterations in NMDA receptor subunit densities and ligand binding to glycine recognition sites are associated with chronic anxiety in Alzheimer's disease
    • Tsang S.W., Vinters H.V., Cummings J.L., Wong P.T., Chen C.P., Lai M.K. Alterations in NMDA receptor subunit densities and ligand binding to glycine recognition sites are associated with chronic anxiety in Alzheimer's disease. Neurobiol. Aging 2008, 29:1524-1532.
    • (2008) Neurobiol. Aging , vol.29 , pp. 1524-1532
    • Tsang, S.W.1    Vinters, H.V.2    Cummings, J.L.3    Wong, P.T.4    Chen, C.P.5    Lai, M.K.6
  • 159
    • 33746210128 scopus 로고    scopus 로고
    • Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease
    • Tsang S.W., Lai M.K., Kirvell S., Francis P.T., Esiri M.M., Hope T., Chen C.P., Wong P.T. Impaired coupling of muscarinic M1 receptors to G-proteins in the neocortex is associated with severity of dementia in Alzheimer's disease. Neurobiol. Aging 2006, 27:1216-1223.
    • (2006) Neurobiol. Aging , vol.27 , pp. 1216-1223
    • Tsang, S.W.1    Lai, M.K.2    Kirvell, S.3    Francis, P.T.4    Esiri, M.M.5    Hope, T.6    Chen, C.P.7    Wong, P.T.8
  • 161
    • 8444244974 scopus 로고    scopus 로고
    • Nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles
    • Turner T.J. Nicotine enhancement of dopamine release by a calcium-dependent increase in the size of the readily releasable pool of synaptic vesicles. J. Neurosci. 2004, 24(50):11328-11336.
    • (2004) J. Neurosci. , vol.24 , Issue.50 , pp. 11328-11336
    • Turner, T.J.1
  • 162
    • 0026751316 scopus 로고
    • N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease
    • Ulas J., Brunner L.C., Geddes J.W., Choe W., Cotman C.W. N-methyl-d-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease. Neuroscience 1992, 49:45-61.
    • (1992) Neuroscience , vol.49 , pp. 45-61
    • Ulas, J.1    Brunner, L.C.2    Geddes, J.W.3    Choe, W.4    Cotman, C.W.5
  • 163
    • 46749118971 scopus 로고    scopus 로고
    • 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease
    • Upton N., Chuang T.T., Hunter A.J., Virley D.J. 5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease. Neurotherapeutics 2008, 5:458-469.
    • (2008) Neurotherapeutics , vol.5 , pp. 458-469
    • Upton, N.1    Chuang, T.T.2    Hunter, A.J.3    Virley, D.J.4
  • 166
    • 33947239285 scopus 로고    scopus 로고
    • Diagnostic value of asymmetric striatal D2 receptor upregulation in Parkinson's disease: an [123I]IBZM and [123I]FP-CIT SPECT study
    • Verstappen C.C., Bloem B.R., Haaxma C.A., Oyen W.J., Horstink M.W. Diagnostic value of asymmetric striatal D2 receptor upregulation in Parkinson's disease: an [123I]IBZM and [123I]FP-CIT SPECT study. Eur. J. Nucl. Med. Mol. Imaging 2007, 34:502-507.
    • (2007) Eur. J. Nucl. Med. Mol. Imaging , vol.34 , pp. 502-507
    • Verstappen, C.C.1    Bloem, B.R.2    Haaxma, C.A.3    Oyen, W.J.4    Horstink, M.W.5
  • 167
    • 59149087458 scopus 로고    scopus 로고
    • Alpha1-adrenoceptors mediate dihydroxyphenylalanine-induced activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaques
    • Visanji N.P., Fox S.H., Johnston T.H., Millan M.J., Brotchie J.M. Alpha1-adrenoceptors mediate dihydroxyphenylalanine-induced activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaques. J. Pharmacol. Exp. Ther. 2009, 328(1):276-283.
    • (2009) J. Pharmacol. Exp. Ther. , vol.328 , Issue.1 , pp. 276-283
    • Visanji, N.P.1    Fox, S.H.2    Johnston, T.H.3    Millan, M.J.4    Brotchie, J.M.5
  • 168
    • 19444382315 scopus 로고    scopus 로고
    • Simvastatin reverses the downregulation of dopamine D1 and D2 receptor expression in the prefrontal cortex of 6-hydroxydopamine-induced Parkinsonian rats
    • Wang Q., Wang P.H., McLachlan C., Wong P.T. Simvastatin reverses the downregulation of dopamine D1 and D2 receptor expression in the prefrontal cortex of 6-hydroxydopamine-induced Parkinsonian rats. Brain Res. 2005, 1045:229-233.
    • (2005) Brain Res. , vol.1045 , pp. 229-233
    • Wang, Q.1    Wang, P.H.2    McLachlan, C.3    Wong, P.T.4
  • 169
    • 17844411468 scopus 로고    scopus 로고
    • High doses of simvastatin upregulate dopamine D1 and D2 receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase
    • Wang Q., Ting W.L., Yang H., Wong P.T. High doses of simvastatin upregulate dopamine D1 and D2 receptor expression in the rat prefrontal cortex: possible involvement of endothelial nitric oxide synthase. Br. J. Pharmacol. 2005, 144(7):933-939.
    • (2005) Br. J. Pharmacol. , vol.144 , Issue.7 , pp. 933-939
    • Wang, Q.1    Ting, W.L.2    Yang, H.3    Wong, P.T.4
  • 170
    • 46549089034 scopus 로고    scopus 로고
    • Chronic treatment with simvastatin upregulates muscarinic M1/4 receptor binding in the rat brain
    • Wang Q., Zengin A., Ying W., Newell K.A., Wang P., Yeo W., Wong P.T., Yenari M.A., Huang X.F. Chronic treatment with simvastatin upregulates muscarinic M1/4 receptor binding in the rat brain. Neuroscience 2008, 154(3):1100-1106.
    • (2008) Neuroscience , vol.154 , Issue.3 , pp. 1100-1106
    • Wang, Q.1    Zengin, A.2    Ying, W.3    Newell, K.A.4    Wang, P.5    Yeo, W.6    Wong, P.T.7    Yenari, M.A.8    Huang, X.F.9
  • 171
    • 59749088704 scopus 로고    scopus 로고
    • High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: the association with the up-regulation of NMDA receptor binding in the rat brain
    • Wang Q., Zengin A., Deng C., Li Y., Newell K.A., Yang G.Y., Lu Y., Wilder-Smith E.P., Zhao H., Huang X.F. High dose of simvastatin induces hyperlocomotive and anxiolytic-like activities: the association with the up-regulation of NMDA receptor binding in the rat brain. Exp. Neurol. 2009, 216(1):132-138.
    • (2009) Exp. Neurol. , vol.216 , Issue.1 , pp. 132-138
    • Wang, Q.1    Zengin, A.2    Deng, C.3    Li, Y.4    Newell, K.A.5    Yang, G.Y.6    Lu, Y.7    Wilder-Smith, E.P.8    Zhao, H.9    Huang, X.F.10
  • 172
    • 43249103338 scopus 로고    scopus 로고
    • Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: potential targets for the development of new therapeutic agents
    • Ward R.J., Lallemand F., de Witte P., Dexter D.T. Neurochemical pathways involved in the protective effects of nicotine and ethanol in preventing the development of Parkinson's disease: potential targets for the development of new therapeutic agents. Prog. Neurobiol. 2008, 85(2):135-147.
    • (2008) Prog. Neurobiol. , vol.85 , Issue.2 , pp. 135-147
    • Ward, R.J.1    Lallemand, F.2    de Witte, P.3    Dexter, D.T.4
  • 173
    • 70349734329 scopus 로고    scopus 로고
    • Activation of the 5-HT(6) receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus
    • West P.J., Marcy V.R., Marino M.J., Schaffhauser H. Activation of the 5-HT(6) receptor attenuates long-term potentiation and facilitates GABAergic neurotransmission in rat hippocampus. Neuroscience 2009, 164:692-701.
    • (2009) Neuroscience , vol.164 , pp. 692-701
    • West, P.J.1    Marcy, V.R.2    Marino, M.J.3    Schaffhauser, H.4
  • 174
    • 0033302309 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in Alzheimer's disease
    • Wevers A., Schroder H. Nicotinic acetylcholine receptors in Alzheimer's disease. J. Alzheimers Dis. 1999, 1:207-219.
    • (1999) J. Alzheimers Dis. , vol.1 , pp. 207-219
    • Wevers, A.1    Schroder, H.2
  • 175
    • 0028222272 scopus 로고
    • Glutamate receptors in striatum and substantia nigra: effects of medial forebrain bundle lesions
    • Wullner U., Testa C.M., Catania M.V., Young A.B., Penney J.B. Glutamate receptors in striatum and substantia nigra: effects of medial forebrain bundle lesions. Brain Res. 1994, 645:98-102.
    • (1994) Brain Res. , vol.645 , pp. 98-102
    • Wullner, U.1    Testa, C.M.2    Catania, M.V.3    Young, A.B.4    Penney, J.B.5
  • 176
    • 3042651847 scopus 로고    scopus 로고
    • Activation of NR1a/NR2B receptors by soluble factors from APP-stimulated monocyte-derived macrophages: implications for the pathogenesis of Alzheimer's disease
    • Xiong H., McCabe L., Costello J., Anderson E., Weber G., Ikezu T. Activation of NR1a/NR2B receptors by soluble factors from APP-stimulated monocyte-derived macrophages: implications for the pathogenesis of Alzheimer's disease. Neurobiol. Aging 2004, 25:905-911.
    • (2004) Neurobiol. Aging , vol.25 , pp. 905-911
    • Xiong, H.1    McCabe, L.2    Costello, J.3    Anderson, E.4    Weber, G.5    Ikezu, T.6
  • 177
  • 180
    • 42749086112 scopus 로고    scopus 로고
    • Polymorphisms at the beta2-adrenergic receptor gene influence Alzheimer's disease susceptibility
    • Yu J.T., Tan L., Ou J.R., Zhu J.X., Liu K., Song J.H., Sun Y.P. Polymorphisms at the beta2-adrenergic receptor gene influence Alzheimer's disease susceptibility. Brain Res. 2008, 1210:216-222.
    • (2008) Brain Res. , vol.1210 , pp. 216-222
    • Yu, J.T.1    Tan, L.2    Ou, J.R.3    Zhu, J.X.4    Liu, K.5    Song, J.H.6    Sun, Y.P.7
  • 181
    • 0030898061 scopus 로고    scopus 로고
    • Membrane-delimited modulation of NMDA currents by metabotropic glutamate receptor subtypes 1/5 in cultured mouse cortical neurons
    • Yu S.P., Sensi S.L., Canzoniero L.M., Buisson A., Choi D.W. Membrane-delimited modulation of NMDA currents by metabotropic glutamate receptor subtypes 1/5 in cultured mouse cortical neurons. J. Physiol. 1997, 499(Pt 3):721-732.
    • (1997) J. Physiol. , vol.499 , Issue.PART 3 , pp. 721-732
    • Yu, S.P.1    Sensi, S.L.2    Canzoniero, L.M.3    Buisson, A.4    Choi, D.W.5
  • 182
    • 0033537735 scopus 로고    scopus 로고
    • NMDA receptor-mediated K+ efflux and neuronal apoptosis
    • Yu S.P., Yeh C., Strasser U., Tian M., Choi D.W. NMDA receptor-mediated K+ efflux and neuronal apoptosis. Science 1999, 284(5412):336-339.
    • (1999) Science , vol.284 , Issue.5412 , pp. 336-339
    • Yu, S.P.1    Yeh, C.2    Strasser, U.3    Tian, M.4    Choi, D.W.5
  • 183
    • 0034807730 scopus 로고    scopus 로고
    • D(4) dopamine receptor differentially regulates Akt/nuclear factor-kappa b and extracellular signal-regulated kinase pathways in D(4)MN9D cells
    • Zhen X., Zhang J., Johnson G.P., Friedman E. D(4) dopamine receptor differentially regulates Akt/nuclear factor-kappa b and extracellular signal-regulated kinase pathways in D(4)MN9D cells. Mol. Pharmacol. 2001, 60(4):857-864.
    • (2001) Mol. Pharmacol. , vol.60 , Issue.4 , pp. 857-864
    • Zhen, X.1    Zhang, J.2    Johnson, G.P.3    Friedman, E.4
  • 184
    • 0036893701 scopus 로고    scopus 로고
    • Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease
    • Zhen X., Torres C., Cai G., Friedman E. Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease. Mol. Pharmacol. 2002, 62:1356-1363.
    • (2002) Mol. Pharmacol. , vol.62 , pp. 1356-1363
    • Zhen, X.1    Torres, C.2    Cai, G.3    Friedman, E.4


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