Aβ-mediated NMDA receptor endocytosis in alzheimer's disease involves ubiquitination of the tyrosine phosphatase STEP61

Journal of Neuroscience

Volumn 30, Issue 17, 2010, Pages 5948-5957

  Kurup, Pradeep ^a   Zhang, Yongfang ^a   Xu, Jian ^a   Venkitaramani, Deepa V ^a,e   Haroutunian, Vahram ^c   Greengard, Paul ^d   Nairn, Angus C ^b   Lombroso, Paul J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d ROCKEFELLER UNIVERSITY   (United States)

^e UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; PROTEASOME; PROTEIN TYROSINE PHOSPHATASE; STRIATAL ENRICHED PROTEIN TYROSINE PHOSPHATASE 61; UBIQUITIN; UNCLASSIFIED DRUG; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE; NR1 NMDA RECEPTOR; NR2B NMDA RECEPTOR; PTPN5 PROTEIN, HUMAN; PTPN5 PROTEIN, MOUSE; UBIQUITINATED PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BIOTINYLATION; BRAIN; BRAIN CORTEX; BRAIN SLICE; COGNITIVE DEFECT; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN TISSUE; INTERNALIZATION; KNOCKOUT GENE; MOUSE; NERVE CELL CULTURE; NERVE CELL MEMBRANE; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; UBIQUITINATION; WILD TYPE; AGED; ANIMAL; CELL CULTURE; CELL LINE; IN VITRO STUDY; METABOLISM; MIDDLE AGED; MOUSE MUTANT; NERVE CELL; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TRANSGENIC MOUSE;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; CELL LINE; CELLS, CULTURED; CEREBRAL CORTEX; ENDOCYTOSIS; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MIDDLE AGED; NEURONS; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; UBIQUITINATED PROTEINS; UBIQUITINATION;

EID: 77951653236     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0157-10.2010     Document Type: Article

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