5-HT(1A) receptors modulate the consolidation of learning in normal and cognitively impaired rats

Neurobiology of Learning and Memory

Volumn 71, Issue 2, 1999, Pages 207-218

  Meneses, Alfredo ^a   Hong, Enrique ^a  

^a DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

5 HT(1A); Autoshaping; Learning; Rats; Receptors; Serotonin

Indexed keywords

2 DIPROPYLAMINO 5 FLUORO 8 HYDROXYTETRALIN; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; CHLORAMPHETAMINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; DIZOCILPINE; GLUTAMATE RECEPTOR ANTAGONIST; KETANSERIN; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; ONDANSETRON; SCOPOLAMINE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 1B ANTAGONIST; SEROTONIN 1D ANTAGONIST; SEROTONIN 2A ANTAGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 3 ANTAGONIST; AMINO ACID RECEPTOR BLOCKING AGENT; NEUROTRANSMITTER RECEPTOR; PRESYNAPTIC RECEPTOR; SEROTONIN ANTAGONIST;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; LEARNING; MALE; MEMORY CONSOLIDATION; NONHUMAN; RAT; SEROTONINERGIC SYSTEM; ANIMAL; COGNITIVE DEFECT; COMPARATIVE STUDY; CONDITIONING; DRUG EFFECT; WISTAR RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; CHOLINERGIC ANTAGONISTS; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); EXCITATORY AMINO ACID ANTAGONISTS; LEARNING; MALE; P-CHLOROAMPHETAMINE; RATS; RATS, WISTAR; RECEPTORS, NEUROTRANSMITTER; RECEPTORS, PRESYNAPTIC; SCOPOLAMINE; SEROTONIN ANTAGONISTS;

EID: 0032588309     PISSN: 10747427     EISSN: None     Source Type: Journal    
DOI: 10.1006/nlme.1998.3866     Document Type: Article

References (48)

1. Aghajanian G. K. Electrophysiology of serotonin receptor subtypes and signal transduction pathways. Psychopharmacology: The fourth generation of progress. 1995;Raven, New York. p. 451-460.
2. Altman H. J., Normile H. J. What is the nature of the role of the serotonergic nervous system in learning and memory: Prospects for development of an effective treatment strategy for senile dementia. Neurobiology of Aging. 9:1988;627-638.
3. 1A. Drug Development Research. 26:1992;275-286.
4. Azmitia, E. C. Whitaker-Azmitia, P. M. 1995, Anatomy, cell biology, and plasticity of serotonergic system, In, E. F. BloomD. J. Kupfer, Psychopharmacology: The fourth generation of progress, 443, 449, New York, Raven.
5. Bartolomeo A. C., Morris H., Moyer J. A., Boast C. A. Attenuated MK-801-induced impairment of radial maze performance in rats: A possible model predicting efficacy in Alzheimer's disease. Society of Neuroscience Abstract. 22:1996;143.
6. Berendsen H. H. G. Interactions between 5-hydroxytryptamine receptor subtypes: Is a disturbed receptor balance contributing to the symptomatology of depression in humans. Pharmacology and Therapeutic. 66:1995;17-37.
7. Blier P., Lista A., De Montigny C. Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus. 1. Effect of spiperone. Journal of Pharmacology Experimental Therapeutic. 265:1993;7-15.
8. 1A. Behavioral Brain Research. 67:1995;67-74.
9. Cassel J. C., Jeltsch H. Serotonergic modulation of cholinergic function in the central nervous system: Cognitive Implications. Neuroscience. 69:1995;1-41.
10. 1A. Current Drugs: Serotonin. 1993;99-124.
11. 1A. Psychopharmacology. 116:1994;135-142.
12. 1A. Pharmacology Biochemistry Behavioral. 55:1996;1-10.
13. 1A. British Journal of Pharmacology. 115:1995;1169-1174.
14. Fink K., Böing C., Göthert M. Presynaptic 5-HT autoreceptors modulate N-methyl-D-aspartate-evoked 5-hydroxytryptamine release in the guinea-pig brain cortex. European Journal of Pharmacology. 300:1996;79-82.
15. 1A2. Journal of Pharmacology and Experimental Therapeutic. 261:1992;1273-1281.
16. 1A. Trends in Pharmacological Sciences. 14:1993;441-448.
17. 1A. Behavioral Brain Research. 73:1996;337-353.
18. Fujii T., Yoshizawa M., Nakai K., Fujimoto K., Suzuki T., Kawashima K. Demonstration of the facilitatory role of 8-OH-DPAT on cholinergic transmission in the rat hippocampus using in vivo microdialysis. Brain Research. 761:1997;244-249.
19. Fletcher P. J. Dopamine receptor blockade in nucleus accumbens or caudate nucleus differentially affects feeding induced by 8-OH-DPAT injected into dorsal or median raphe. Brain Research. 552:1991;181-189.
20. Glennon, R. A. Dukat, M. 1995, Serotonin receptor subtypes, In, F. E. BloomD. J. Kupfer, Psychopharmacology: The fourth generation of progress, 415, 429, New York, Raven.
21. 1A. Psychopharmacology. 127:1996;245-254.
22. Heninger, G. R. 1995, Indolamines: The role of serotonin in clinical disorders, In, E. F. BloomD. J. Kupfer, Psychopharmacology: The fourth generation of progress, 471, 482, New York, Raven.
23. 1A. Journal of Psychopharmacology. 9:1995;242-250.
24. 3. Psychopharmacology. 125:1996;146-161.
25. Hoyer D., Hartig P. R., Humphrey P. P. A. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacological Reviews. 46:1994;157-203.
26. Hoyer D., Martin G. 5-HT receptor classification and nomenclature: Towards a harmonization with the human genome. Neuropharmacology. 36:1997;419-428.
27. Jacobs B. L., Azmitia E. C. Structure and function of the brain serotonin system. Physiological Reviews. 72:1992;165-229.
28. 1A1A. Brain Research. 739:1996;192-200.
29. McGaugh J. L. Dissociating learning and performance: Drug and hormone enhancement of memory storage. Brain Research Bulletin. 23:1989;339-345.
30. Meneses A. 5-HT receptors as targets for drugs in the treatment of learning and memory dysfunctions. Current Research in Serotonin. 3:1998;219-228.
31. Meneses A., Hong E. Modification of 8-OH-DPAT effect on learning by manipulation of the assay conditions. Behavioral Neural Biology. 61:1994a;29-35.
32. Meneses A., Hong E. Mechanisms of action of 8-OH-DPAT on learning and memory. Pharmacology Biochemistry Behavior. 49:1994b;1083-1086.
33. Meneses A., Hong E. A pharmacological analysis of serotonergic receptors: Effects of their activation or blockade in learning. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 21:1997a;273-296.
34. 1A. CNS Drug Review. 3:1997b;68-82.
35. O'Dowd B. S., Zhao W. Q., Ng K. T., Robinson S. R. Chicks injected with antisera to either S-100α or S-100β protein develop amnesia for a passive avoidance task. Neurobiology of Learning and Memory. 67:1997;197-206.
36. 1A. European Journal of Pharmacology. 262:1994;77-90.
37. (1A). Brain Research. 649:1994;174-180.
38. 1A. Psychopharmacology. 122:1995;137-146.
39. Samanin R., Luschi R., Vezzani A., Carli M. Impairment of spatial learning induced by intra-hippocampal scopolamine: Its reversal by arecoline, ondansetron and intrahippocampal (+)-WAY 100135. Society of Neuroscience Abstracts. 20:1994;149.
40. Sirviö J., Riekkinen P., Jäkälä P., Riekkinen P. J. Experimental studies on the role of serotonin in cognition. Progress in Neurobiology. 43:1994;363-379.
41. Stanhope K. J., McLenachan A. P., Dourish C. T. Dissociation between cognitive and motor/motivational deficits in the delayed matching to position test: Effects of scopolamine, 8-OH-DPAT, and EAA antagonists. Psychopharmacology. 122:1995;268-280.
42. 1A1A, Society of Neuroscience Abstracts, 22, 1322.
43. 1A. Perspectives Development Neurobiology. 2:1994;233-238.
44. 1A1C2. Journal Comparative Neurology. 351:1995;357-373.
45. 1A. Society of Neuroscience Abstracts. 22:1996;1327.
46. 3. Neuropharmacology. 33:1994;483-491.
47. Zifa E., Fillion G. 5-Hydroxytryptamine receptors. Pharmacological Reviews. 44:1992;401-458.
48. Zola-Morgan S., Squire L. R. Neuroanatomy of memory. Annual Review of Neuroscience. 16:1993;547-563.