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Volumn 20, Issue 4, 2012, Pages 1373-1379
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Synthesis, molecular docking and biological evaluation of 1,3,4-oxadiazole derivatives as potential immunosuppressive agents
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Author keywords
Immunosuppressive activity; Molecular docking; Oxadiazoles; PI3K
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Indexed keywords
1 [2 (2 CHLOROPHENYL) 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [2 (2,4 DICHLOROPHENYL) 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [2 (3 BROMOPHENYL) 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [2 [4 (BENZYLOXY)PHENYL] 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (2 FLUOROPHENYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (3 FLUOROPHENYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (3 METHOXYPHENYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (4 FLUOROPHENYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (4 METHOXYPHENYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (4 NITROPHENYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (4 TOLYL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 (NAPHTHALEN 1 YL) 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1 [5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2 PHENYL 1,3,4 OXADIAZOL 3(2H) YL]ETHANONE;
1,3,4 OXADIAZOLE DERIVATIVE;
2 [3 ACETYL 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2,3 DIHYDRO 1,3,4 OXADIAZOL 2 YL] 4 BROMOPHENYL ACETATE;
2 [3 ACETYL 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2,3 DIHYDRO 1,3,4 OXADIAZOL 2 YL] 4 CHLOROPHENYL ACETATE;
2 [3 ACETYL 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2,3 DIHYDRO 1,3,4 OXADIAZOL 2 YL] 4,6 DIBROMOPHENYL ACETATE;
2 [3 ACETYL 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2,3 DIHYDRO 1,3,4 OXADIAZOL 2 YL] 4,6 DICHLOROPHENYL ACETATE;
2 [3 ACETYL 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2,3 DIHYDRO 1,3,4 OXADIAZOL 2 YL]PHENYL ACETATE;
4 [3 ACETYL 5 (2,3 DIHYDROBENZO[B][1,4]DIOXIN 6 YL) 2,3 DIHYDRO 1,3,4 OXADIAZOL 2 YL]PHENYL ACETATE;
CASPASE 3;
IMMUNOSUPPRESSIVE AGENT;
PHOSPHATIDYLINOSITOL 3 KINASE;
PROTEIN KINASE B;
UNCLASSIFIED DRUG;
ANTIINFLAMMATORY ACTIVITY;
APOPTOSIS;
ARTICLE;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
CRYSTAL STRUCTURE;
CYTOTOXICITY TEST;
DRUG BINDING SITE;
DRUG DESIGN;
DRUG POTENCY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENZYME INHIBITION;
FLOW CYTOMETRY;
HYDROGEN BOND;
IC 50;
LYMPH NODE CELL;
MOLECULAR DOCKING;
PROTEIN CLEAVAGE;
STRUCTURE ACTIVITY RELATION;
WESTERN BLOTTING;
APOPTOSIS;
BLOTTING, WESTERN;
CELL LINE, TUMOR;
CRYSTALLOGRAPHY, X-RAY;
FLOW CYTOMETRY;
HUMANS;
IMMUNOSUPPRESSIVE AGENTS;
LYMPH NODES;
MODELS, MOLECULAR;
OXADIAZOLES;
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EID: 84862778161
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2012.01.023 Document Type: Article |
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Times cited : (20)
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References (31)
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