3-Acetyl-2,5-diaryl-2,3-dihydro-1,3,4-oxadiazoles: A new scaffold for the selective inhibition of monoamine oxidase B

Journal of Medicinal Chemistry

Volumn 54, Issue 18, 2011, Pages 6394-6398

  MacCioni, Elias ^a   Alcaro, Stefano ^b   Cirilli, Roberto ^c   Vigo, Sara ^a   Cardia, Maria Cristina ^a   Sanna, Maria Luisa ^a   Meleddu, Rita ^a   Yanez, Matilde ^d   Costa, Giosuè ^b   Casu, Laura ^a   Matyus, Peter ^e   Distinto, Simona ^b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b University of Catanzaro Magna Graecia   (Italy)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^e SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4 OXADIAZOLE DERIVATIVE; 3 ACETYL 2,5 DIARYL 2,3 DIHYDR 1,3,4 OXADIAZOLE; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; MONOAMINE OXIDASE B INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG BINDING; DRUG DESIGN; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MOLECULAR DOCKING; NONHUMAN; RACEMIC MIXTURE;

ANIMALS; CELL LINE; DRUG DESIGN; HUMANS; INSECTS; ISOENZYMES; MODELS, MOLECULAR; MONOAMINE OXIDASE INHIBITORS; OXADIAZOLES; PROTEIN BINDING; RECOMBINANT PROTEINS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80052785419     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2002876     Document Type: Article

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