1,3,4-Oxadiazole/thiadiazole and 1,2,4-triazole derivatives of biphenyl-4-yloxy acetic acid: Synthesis and preliminary evaluation of biological properties

European Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2008, Pages 2688-2698

  Kumar, Harish ^a   Javed, Sadique A ^a   Khan, Suroor A ^a   Amir, Mohammad ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

1,2,4 Triazole; 1,3,4 Oxadiazole thiadiazoles; Analgesic; Anti inflammatory; Lipid peroxidation; Ulcerogenic

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 1,3,4 OXADIAZOLE DERIVATIVE; 1,3,4 THIADIAZOLE DERIVATIVE; 5 [(BIPHENYL 4 YLOXY)METHYL] 2 (4 CHLOROPHENYL) 1,3,4 OXADIAZOLE; 5 [(BIPHENYL 4 YLOXY)METHYL] 2 [1 (4 ISOBUTYLPHENYL)ETHYL] 1,3,4 OXADIAZOLE; 5 [(BIPHENYL 4 YLOXY)METHYL] 4 (4 FLUOROPHENYL) 3 MERCAPTO (4H) 1,2,4 TRIAZOLE; 5 [(BIPHENYL 4 YLOXY)METHYL] 4 BUTYL 3 MERCAPTO (4H) 1,2,4 TRIAZOLE; ACETIC ACID DERIVATIVE; BIPHENYL 4 YLOXY ACETIC ACID DERIVATIVE; FLURBIPROFEN; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; FEMALE; LIPID PEROXIDATION; MALE; NONHUMAN; PAW EDEMA; PROTECTION; RAT; REACTION ANALYSIS; ULCEROGENESIS;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; ANTIOXIDANTS; CARRAGEENAN; DIPHENYLACETIC ACIDS; DRUG EVALUATION, PRECLINICAL; EDEMA; FEMALE; GASTRIC MUCOSA; LIPID PEROXIDATION; LIVER; MALE; MICE; MOLECULAR STRUCTURE; OXADIAZOLES; RATS; RATS, WISTAR; STEREOISOMERISM; STOMACH ULCER; THIADIAZOLES; TRIAZOLES;

EID: 56949101987     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.01.039     Document Type: Article

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