Synthesis of substituted acridinyl pyrazoline derivatives and their evaluation for anti-inflammatory activity

European Journal of Medicinal Chemistry

Volumn 45, Issue 5, 2010, Pages 1772-1776

  Chandra, Trilok ^a   Garg, Neha ^a   Lata, Suman ^a   Saxena, K K ^a   Kumar, Ashok ^a  

^a LLRM MEDICAL COLLEGE   (India)

Author keywords

Acridine; Analgesic activity; Anti inflammatory activity; Oxadiazole; Pyrazol 5 ones

Indexed keywords

1 (2' BROMOACRIDIN 9' YL) 3 (5' PYRIDIN 4 YL)(1,3,4 OXADIAZOL 2 YL THIOMETHYL)PYRAZOL 5 ONE; 1 (2' BROMOACRIDIN 9' YL) 3 (BROMOMETHYL)PYRAZOL 5 ONE; 1 (2' CHLOROACRIDIN 9' YL) 3 (BROMOMETHYL)PYRAZOL 5 ONE; 1 (2' METHOXYACRIDIN 9' YL) 3 (5' PYRIDIN 4 YL)(1,3,4 OXADIAZOL 2 YL THIOMETHYL)PYRAZOL 5 ONE; 1 (2' METHOXYACRIDIN 9' YL) 3 (BROMOMETHYL)PYRAZOL 5 ONE; 1 (2',4' CHLOROACRIDIN 9' YL) 3 (5' PYRIDIN 4 YL)(1,3,4 OXADIAZOL 2 YL THIOMETHYL)PYRAZOL 5 ONE; 1 (2',4' DICHLOROACRIDIN 9' YL) 3 (BROMOMETHYL)PYRAZOL 5 ONE; 1 (2',4' DICHLOROACRIDIN 9' YL) 3 METHYL PYRAZOL 5 ONE; 1 (2'CHLOROACRIDIN 9' YL) 3 (5' PYRIDIN 4 YL)(1,3,4 OXADIAZOL 2 YL THIOMETHYL)PYRAZOL 5 ONE; 1 (20,40 CHLOROACRIDINE 90 YL) 3 (50 PYRIDINE 4 YL)(1,3,4 OXADIAZOL 2 YLTHIOMETHYL)PYRAZOLE 5 ONE; 1 (4' CHLORO 2' METHOXYACRIDIN 9' YL) 3 (5' PYRIDIN 4 YL)(1,3,4 OXADIAZOL 2 YL THIOMETHYL)PYRAZOL 5 ONE; 1 (4' CHLORO 2' METHOXYACRIDIN 9' YL) 3 (BROMOMETHYL)PYRAZOL 5 ONE; 1 (ACRIDIN 9' YL) 3 (5' PYRIDIN 4 YL)(1,3,4 OXADIAZOL 2 YLTHIOMETHYL)PYRAZOL 5 ONE; 1 (ACRIDIN 9' YL) 3 (BROMOMETHYL)PYRAZOL 5 ONE; 1 (ACRIDIN 9' YL) 3 METHYL PYRAZOL 5 ONE; ACETYLSALICYLIC ACID; ANTIINFLAMMATORY AGENT; PHENYLBUTAZONE; PYRAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; EDEMA; FEMALE; LD 50; MALE; MOUSE; NONHUMAN; PAIN; RAT;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG EVALUATION, PRECLINICAL; MOLECULAR STRUCTURE; PYRAZOLES; RATS; STEREOISOMERISM;

EID: 77949487261     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2010.01.009     Document Type: Article

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