Dynamic monitoring of β-cell injury with impedance and rescue by glucagon-like peptide-1

Analytical Biochemistry

Volumn 423, Issue 1, 2012, Pages 61-69

  Guan, Ni ^a   Gao, Weiwei ^a   He, Min ^a   Zheng, Min ^b   Xu, Xiao ^a,b   Wang, Xiaobo ^b   Wang, Ming Wei ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b Hangzhou High Throughput Drug Screening Center   (China)

Author keywords

Boc5; Cytokines; Free fatty acids; Glucagon like peptide 1; Hydrogen peroxide; Streptozotocin; xCELLigence system; Cell injury

Indexed keywords

CELL CULTURE; FATTY ACIDS; HYDROGEN PEROXIDE; MIXTURES; OXIDATION; PEPTIDES; PEROXIDES;

BOC5; CELL INJURY; CYTOKINES; FREE FATTY ACID; GLUCAGON-LIKE PEPTIDE-1; STREPTOZOTOCIN; XCELLIGENCE SYSTEM;

CELLS;

CYTOKINE; FATTY ACID; GLUCAGON LIKE PEPTIDE 1; HYDROGEN PEROXIDE; STREPTOZOCIN;

ANIMAL CELL; ARTICLE; BIOASSAY; CELL PROTECTION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DYNAMICS; IMPEDANCE; INSULIN DEPENDENT DIABETES MELLITUS; MONITORING; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS INJURY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

EID: 84862777490     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2012.01.014     Document Type: Article

References (47)

1. D.T. Finegood, L. Scaglia, S. Bonner-Weir, Dynamics of β-cell mass in the growing rat pancreas: estimation with a simple mathematical model, Diabetes 44 (1995) 249-256.
2. T. Mandrup-Poulsen, β-Cell apoptosis: stimuli and signaling, Diabetes 50 (Suppl 1) (2001) S58-S63.
3. F.J. Lally, H. Ratcliff, A.J. Bone, Apoptosis and disease progression in the spontaneously diabetic BB/S rat, Diabetologia 44 (2001) 320-324. (Pubitemid 32234458)
4. P. Augstein, A.G. Elefanty, J. Allison, L.C. Harrison, Apoptosis and β-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes, Diabetologia 41 (1998) 1381-1388. (Pubitemid 28488768)
5. M. Cnop, N. Welsh, J.C. Jonas, A. Jorns, S. Lenzen, D.L. Eizirik, Mechanisms of pancreatic β-cell death in type 1 and type 2 diabetes: many differences, few similarities, Diabetes 54 (Suppl 2) (2005) S97-S107. (Pubitemid 43343337)
6. J. Saldeen, Cytokines induce both necrosis and apoptosis via a common Bcl-2- inhibitable pathway in rat insulin-producing cells, Endocrinology 141 (2000) 2003-2010. (Pubitemid 32274349)
7. H. Hui, A. Nourparvar, X. Zhao, R. Perfetti, Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5′-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway, Endocrinology 144 (2003) 1444-1455. (Pubitemid 36432086)
8. 2-triggered apoptosis: a cAMP-dependent adaptive response, Am. J. Physiol. Endocrinol. Metab. 298 (2010) E17-E27.
9. D. Tews, S. Lehr, S. Hartwig, A. Osmers, W. Paslack, J. Eckel, Anti-apoptotic action of exendin-4 in INS-1 beta cells: comparative protein pattern analysis of isolated mitochondria, Horm. Metab. Res. 41 (2009) 294-301.
10. I.P. Salt, G. Johnson, S.J. Ashcroft, D.G. Hardie, AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells and may regulate insulin release, Biochem. J. 335 (1998) 533-539. (Pubitemid 28515405)
11. J.F. Kerr, A.H. Wyllie, A.R. Currie, Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics, Br. J. Cancer 26 (1972) 239-257.
12. G. Kroemer, L. Galluzzi, P. Vandenabeele, J. Abrams, E.S. Alnemri, E.H. Baehrecke, M.V. Blagosklonny, W.S. El-Deiry, P. Golstein, D.R. Green, M. Hengartner, R.A. Knight, S. Kumar, S.A. Lipton, W. Malorni, G. Nunez, M.E. Peter, J. Tschopp, J. Yuan, M. Piacentini, B. Zhivotovsky, G. Melino, Classification of cell death: recommendations of the nomenclature committee on cell death, Cell Death Differ. 16 (2009) 3-11.
13. P.A. Botham, Acute systemic toxicity: prospects for tiered testing strategies, Toxicol. In Vitro 18 (2004) 227-230. (Pubitemid 38125203)
14. G. Salazar, D. Liu, C. Liao, L. Batkiewicz, R. Arbing, S.S. Chung, K. Lele, D.J. Wolgemuth, Apoptosis in male germ cells in response to cyclin A1-deficiency and cell cycle arrest, Biochem. Pharmacol. 66 (2003) 1571-1579. (Pubitemid 38373348)
15. R.J. Keogh, New technology for investigating trophoblast function, Placenta 31 (2010) 347-350.
16. E. Urcan, U. Haertel, M. Styllou, R. Hickel, H. Scherthan, F.X. Reichl, Real-time xCELLigence impedance analysis of the cytotoxicity of dental composite components on human gingival fibroblasts, Dent. Mater. 26 (2010) 51-58.
17. J.Z. Xing, L. Zhu, J.A. Jackson, S. Gabos, X.J. Sun, X.B. Wang, X. Xu, Dynamic monitoring of cytotoxicity on microelectronic sensors, Chem. Res. Toxicol. 18 (2005) 154-161. (Pubitemid 40256233)
18. J.M. Atienza, N. Yu, S.L. Kirstein, B. Xi, X. Wang, X. Xu, Y.A. Abassi, Dynamic and label-free cell-based assays using the real-time cell electronic sensing system, Assay Drug Dev. Technol. 4 (2006) 597-607. (Pubitemid 46017403)
19. W. Xu, B. Xi, J. Wu, H. An, J. Zhu, Y. Abassi, S.C. Feinstein, M. Gaylord, B. Geng, H. Yan, W. Fan, M. Sui, X. Wang, X. Xu, Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of β-tubulin at Cys12 and suppression of microtubule dynamics, Mol. Cancer Ther. 8 (2009) 3318-3330.
20. B. Ahren, GLP-1 for type 2 diabetes, Exp. Cell Res. 317 (2011) 1239-1245.
21. I.A. Urusova, L. Farilla, H. Hui, E. D'Amico, R. Perfetti, GLP-1 inhibition of pancreatic islet cell apoptosis, Trends Endocrinol. Metab. 15 (2004) 27-33. (Pubitemid 38198096)
22. J.A. Ehses, V.R. Casilla, T. Doty, J.A. Pospisilik, K.D. Winter, H.U. Demuth, R.A. Pederson, C.H. McIntosh, Glucose-dependent insulinotropic polypeptide promotes β-(INS-1) cell survival via cyclic adenosine monophosphatemediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase, Endocrinology 144 (2003) 4433-4445. (Pubitemid 37204843)
23. D. Chen, J. Liao, N. Li, C. Zhou, Q. Liu, G. Wang, R. Zhang, S. Zhang, L. Lin, K. Chen, X. Xie, F. Nan, A.A. Young, M.W. Wang, A nonpeptidic agonist of glucagon-like peptide 1 receptors with efficacy in diabetic db/db mice, Proc. Natl. Acad. Sci. USA 104 (2007) 943-948. (Pubitemid 46154716)
24. H. Su, M. He, H. Li, Q. Liu, J. Wang, Y. Wang, W. Gao, L. Zhou, J. Liao, A.A. Young, M.W. Wang, Boc5, a non-peptidic glucagon-like peptide-1 receptor agonist, invokes sustained glycemic control and weight loss in diabetic mice, PLoS One 3 (2008) e2892.
25. M. He, H. Su, W. Gao, S.M. Johansson, Q. Liu, X. Wu, J. Liao, A.A. Young, T. Bartfai, M.W. Wang, Reversal of obesity and insulin resistance by a nonpeptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice, PLoS One 5 (2010) e14205.
26. Q. Liu, N. Li, Y. Yuan, H. Lu, X. Wu, C. Zhou, M. He, H. Su, M. Zhang, J. Wang, B. Wang, Y. Wang, D. Ma, Y. Ye, H.C. Weiss, E.R. Gesing, J. Liao, M.W. Wang, Cyclobutane derivatives as novel nonpeptidic small molecule agonists of glucagon-like peptide-1 receptor, J. Med. Chem. 55 (2012) 250-267.
27. L. Li, W. El-Kholy, C.J. Rhodes, P.L. Brubaker, Glucagon-like peptide-1 protects beta cells from cytokine-induced apoptosis and necrosis: role of protein kinase B, Diabetologia 48 (2005) 1339-1349. (Pubitemid 41186100)
28. G. Kwon, K.L. Pappan, C.A. Marshall, J.E. Schaffer, M.L. McDaniel, CAMP dose-dependently prevents palmitate-induced apoptosis by both protein kinase A-and cAMP-guanine nucleotide exchange factor-dependent pathways in β-cells, J. Biol. Chem. 279 (2004) 8938-8945. (Pubitemid 38295955)
29. D. Mokhtari, J.W. Myers, N. Welsh, The MAPK kinase kinase-1 is essential for stress-induced pancreatic islet cell death, Endocrinology 149 (2008) 3046-3053. (Pubitemid 351724506)
30. B. Zhang, Y. Lu, M. Campbell-Thompson, T. Spencer, C. Wasserfall, M. Atkinson, S. Song, a1-Antitrypsin protects β-cells from apoptosis, Diabetes 56 (2007) 1316-1323.
31. E. Shacter, J.A. Williams, R.M. Hinson, S. Senturker, Y.J. Lee, Oxidative stress interferes with cancer chemotherapy: inhibition of lymphoma cell apoptosis and phagocytosis, Blood 96 (2000) 307-313. (Pubitemid 30456486)
32. D.L. Eizirik, M.I. Darville, β-Cell apoptosis and defense mechanisms: lessons from type 1 diabetes, Diabetes 50 (Suppl 1) (2001) S64-S69. (Pubitemid 32148222)
33. A. Natalicchio, F. De Stefano, M.R. Orlando, M. Melchiorre, A. Leonardini, A. Cignarelli, R. Labarbuta, P. Marchetti, S. Perrini, L. Laviola, F. Giorgino, Exendin- 4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFα) and inhibits TNFα-induced apoptosis in insulin-secreting cells, Endocrinology 151 (2010) 2019-2029.
34. K. Maedler, J. Oberholzer, P. Bucher, G.A. Spinas, M.Y. Donath, Monounsaturated fatty acids prevent the deleterious effects of palmitate and high glucose on human pancreatic β-cell turnover and function, Diabetes 52 (2003) 726-733. (Pubitemid 36323580)
35. E. Sargsyan, P. Bergsten, Lipotoxicity is glucose-dependent in INS-1E cells but not in human islets and MIN6 cells, Lipids Health Dis. 10 (2011) 115.
36. S. Kashyap, R. Belfort, A. Gastaldelli, T. Pratipanawatr, R. Berria, W. Pratipanawatr, M. Bajaj, L. Mandarino, R. DeFronzo, K. Cusi, A sustained increase in plasma free fatty acids impairs insulin secretion in nondiabetic subjects genetically predisposed to develop type 2 diabetes, Diabetes 52 (2003) 2461-2474. (Pubitemid 37210533)
37. J.L. Evans, I.D. Goldfine, B.A. Maddux, G.M. Grodsky, Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction?, Diabetes 52 (2003) 1-8. (Pubitemid 36042100)
38. A.M. Vincent, M. Brownlee, J.W. Russell, Oxidative stress and programmed cell death in diabetic neuropathy, Ann. N.Y. Acad. Sci. 959 (2002) 368-383. (Pubitemid 34457577)
39. X.Y. Wang, J. Sun, C. Wang, M. France, A.G. Sheil, Effect of liver transplantation on islet allografts: up-regulation of Fas ligand and apoptosis of T lymphocytes are associated with islet graft tolerance, Transplantation 71 (2001) 102-111. (Pubitemid 32105786)
40. J.W. Cardinal, G.P. Margison, K.J. Mynett, A.P. Yates, D.P. Cameron, R.H. Elder, Increased susceptibility to streptozotocin-induced b-cell apoptosis and delayed autoimmune diabetes in alkylpurine-DNA-N-glycosylase-deficient mice, Mol. Cell. Biol. 21 (2001) 5605-5613. (Pubitemid 32702463)
41. S. Kodama, T. Toyonaga, T. Kondo, K. Matsumoto, K. Tsuruzoe, J. Kawashima, H. Goto, K. Kume, S. Kume, M. Sakakida, E. Araki, Enhanced expression of PDX-1 and Ngn3 by exendin-4 during beta cell regeneration in STZ-treated mice, Biochem. Biophys. Res. Commun. 327 (2005) 1170-1178. (Pubitemid 40137989)
42. M. Skelin, M. Rupnik, A. Cencic, Pancreatic beta cell lines and their applications in diabetes mellitus research, ALTEX 27 (2010) 105-113.
43. N. Ke, X. Wang, X. Xu, Y.A. Abassi, The xCELLigence system for real-time and label-free monitoring of cell viability, Methods Mol. Biol. 740 (2011) 33-43.
44. K. Moodley, C.E. Angel, M. Glass, E.S. Graham, Real-time profiling of NK cell killing of human astrocytes using xCELLigence technology, J. Neurosci. Methods 200 (2011) 173-180.
45. A. Stark, R. Mentlein, Somatostatin inhibits glucagon-like peptide-1-induced insulin secretion and proliferation of RINm5F insulinoma cells, Regul. Pept. 108 (2002) 97-102. (Pubitemid 35239865)
46. M. Cornu, H. Modi, D. Kawamori, R.N. Kulkarni, M. Joffraud, B. Thorens, Glucagon-like peptide-1 increases b-cell glucose competence and proliferation by translational induction of insulin-like growth factor-1 receptor expression, J. Biol. Chem. 285 (2010) 10538-10545.
47. Y.A. Abassi, B. Xi, W. Zhang, P. Ye, S.L. Kirstein, M.R. Gaylord, S.C. Feinstein, X. Wang, X. Xu, Kinetic cell-based morphological screening: prediction of mechanism of compound action and off-target effects, Chem. Biol. 16 (2009) 712-723.