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Volumn 41, Issue 11, 1998, Pages 1381-1388

Apoptosis and beta-cell destruction in pancreatic islets of NOD mice with spontaneous and cyclophosphamide-accelerated diabetes

Author keywords

Beta cell apoptosis; Cyclophosphamide; Diabetes; NOD mouse; T cells

Indexed keywords

CYCLOPHOSPHAMIDE; DNA;

EID: 0031739726     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051080     Document Type: Article
Times cited : (64)

References (32)
  • 1
    • 0022617990 scopus 로고
    • Type I diabetes mellitus. A chronic autoimmune disease
    • Eisenbarth GS (1986) Type I diabetes mellitus. A chronic autoimmune disease. N Engl J Med 314: 1360-1368
    • (1986) N Engl J Med , vol.314 , pp. 1360-1368
    • Eisenbarth, G.S.1
  • 3
    • 0026646694 scopus 로고
    • The murine autoimmune diabetes model: NOD and related strains
    • Kikutani H, Makino S (1992) The murine autoimmune diabetes model: NOD and related strains. Adv Immunol 51: 285-322
    • (1992) Adv Immunol , vol.51 , pp. 285-322
    • Kikutani, H.1    Makino, S.2
  • 4
    • 0028181042 scopus 로고
    • Histological study of pancreatic beta-cell loss in relation to the insulitis process in the non-obese diabetic mouse
    • Signore A, Procaccini E, Toscano AM et al. (1994) Histological study of pancreatic beta-cell loss in relation to the insulitis process in the non-obese diabetic mouse. Histochemistry 101:263-269
    • (1994) Histochemistry , vol.101 , pp. 263-269
    • Signore, A.1    Procaccini, E.2    Toscano, A.M.3
  • 5
    • 0027960613 scopus 로고
    • Course of pancreatic beta-cell destruction in prediabetic NOD mice: A histomorphometric evaluation
    • Debussche X, Lormeau B, Boitard C, Toublanc M, Assan R (1994) Course of pancreatic beta-cell destruction in prediabetic NOD mice: a histomorphometric evaluation. Diabet Metab 20: 282-290
    • (1994) Diabet Metab , vol.20 , pp. 282-290
    • Debussche, X.1    Lormeau, B.2    Boitard, C.3    Toublanc, M.4    Assan, R.5
  • 6
    • 0029759337 scopus 로고    scopus 로고
    • Beta-cell destruction may be a late consequence of the autoimmune process in nonobese diabetic mice
    • Shimada A, Charlton B, Taylor-Edwards C, Fathman CG (1996) Beta-cell destruction may be a late consequence of the autoimmune process in nonobese diabetic mice. Diabetes 45: 1063-1067
    • (1996) Diabetes , vol.45 , pp. 1063-1067
    • Shimada, A.1    Charlton, B.2    Taylor-Edwards, C.3    Fathman, C.G.4
  • 7
    • 0031170822 scopus 로고    scopus 로고
    • Diabetes results from a late change in the autoimmune response of NOD mice
    • Gazda LS, Charlton B, Lafferty KJ (1997) Diabetes results from a late change in the autoimmune response of NOD mice. J Autoimmun 10: 261-270
    • (1997) J Autoimmun , vol.10 , pp. 261-270
    • Gazda, L.S.1    Charlton, B.2    Lafferty, K.J.3
  • 8
    • 0027170778 scopus 로고
    • Presentation of beta-cell antigens to CD4 + and CD8 + T cells of nonobese diabetic mice
    • Shimizu J, Kanagawa O, Unanue ER (1993) Presentation of beta-cell antigens to CD4 + and CD8 + T cells of nonobese diabetic mice. J Immunol 151: 1723-1730
    • (1993) J Immunol , vol.151 , pp. 1723-1730
    • Shimizu, J.1    Kanagawa, O.2    Unanue, E.R.3
  • 9
    • 13344294394 scopus 로고    scopus 로고
    • CD8 T-cell clones from young non-obese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells
    • Wong FS, Visintin I, Wen L, Flavell RA, Janeway CA Jr (1996) CD8 T-cell clones from young non-obese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. J Exp Med 183: 67-76
    • (1996) J Exp Med , vol.183 , pp. 67-76
    • Wong, F.S.1    Visintin, I.2    Wen, L.3    Flavell, R.A.4    Janeway Jr., C.A.5
  • 10
    • 0028294143 scopus 로고
    • Evidence for the role of CD8 + cytotoxic T cells in the destruction of pancreatic β-cells in nonobese diabetic mice
    • Nagata M, Santamaria P, Kawamura T, Utsugi T, Yoon J-W (1994) Evidence for the role of CD8 + cytotoxic T cells in the destruction of pancreatic β-cells in nonobese diabetic mice. J Immunol 152: 2042-2050
    • (1994) J Immunol , vol.152 , pp. 2042-2050
    • Nagata, M.1    Santamaria, P.2    Kawamura, T.3    Utsugi, T.4    Yoon, J.-W.5
  • 11
    • 0030890721 scopus 로고    scopus 로고
    • The role of Fas in autoimmune diabetes
    • Chervonsky AV, Wang Y, Wong FS et al. (1997) The role of Fas in autoimmune diabetes. Cell 89: 17-24
    • (1997) Cell , vol.89 , pp. 17-24
    • Chervonsky, A.V.1    Wang, Y.2    Wong, F.S.3
  • 14
    • 9244232272 scopus 로고    scopus 로고
    • Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: Inhibition by Bcl-2
    • Iwahashi H, Hanafusa T, Eguchi Y et al. (1996) Cytokine-induced apoptotic cell death in a mouse pancreatic beta-cell line: inhibition by Bcl-2. Diabetologia 39: 530-536
    • (1996) Diabetologia , vol.39 , pp. 530-536
    • Iwahashi, H.1    Hanafusa, T.2    Eguchi, Y.3
  • 15
    • 0030175704 scopus 로고    scopus 로고
    • Identification of interleukin 1-induced apoptosis in rat islets using in situ specific labelling of fragmented DNA
    • Dunger A, Augstein P, Schmidt S, Fischer U (1996b) Identification of interleukin 1-induced apoptosis in rat islets using in situ specific labelling of fragmented DNA. J Autoimmun 9: 309-313
    • (1996) J Autoimmun , vol.9 , pp. 309-313
    • Dunger, A.1    Augstein, P.2    Schmidt, S.3    Fischer, U.4
  • 16
    • 0030444560 scopus 로고    scopus 로고
    • Destruction of rat pancreatic islet beta cells by cytokines involves the production of cytotoxic aldehydes
    • Suarez-Pinzon WL, Strynadka K, Rabinovitch A (1996) Destruction of rat pancreatic islet beta cells by cytokines involves the production of cytotoxic aldehydes. Endocrinology 137: 5290-5296
    • (1996) Endocrinology , vol.137 , pp. 5290-5296
    • Suarez-Pinzon, W.L.1    Strynadka, K.2    Rabinovitch, A.3
  • 17
    • 0029050456 scopus 로고
    • Cell death: Current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo
    • Columbano A (1995) Cell death: Current difficulties in discriminating apoptosis from necrosis in the context of pathological processes in vivo. J Cell Biochem 58: 181-190
    • (1995) J Cell Biochem , vol.58 , pp. 181-190
    • Columbano, A.1
  • 18
    • 0029965136 scopus 로고    scopus 로고
    • The molecular biology of apoptosis
    • Vaux DL and Strasser A (1996) The molecular biology of apoptosis. Proc Natl Acad Sci USA 93: 2239-2244
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2239-2244
    • Vaux, D.L.1    Strasser, A.2
  • 19
    • 0030923812 scopus 로고    scopus 로고
    • Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells
    • Delaney CA, Pavlovic D, Hoorens A, Pipeleers DG, Eizirik DL (1997) Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology 138: 2610-2614
    • (1997) Endocrinology , vol.138 , pp. 2610-2614
    • Delaney, C.A.1    Pavlovic, D.2    Hoorens, A.3    Pipeleers, D.G.4    Eizirik, D.L.5
  • 20
    • 1842289172 scopus 로고    scopus 로고
    • Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
    • Kägi D, Odermatt B, Seiler P, Zinkernagel RM, Mak TW, Hengartner H (1997) Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J Exp Med 186:989-997
    • (1997) J Exp Med , vol.186 , pp. 989-997
    • Kägi, D.1    Odermatt, B.2    Seiler, P.3    Zinkernagel, R.M.4    Mak, T.W.5    Hengartner, H.6
  • 21
    • 0030800122 scopus 로고    scopus 로고
    • Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice
    • Itoh N, Imagawa A, Waguri M et al. (1997) Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice. J Exp Med 186:613-618
    • (1997) J Exp Med , vol.186 , pp. 613-618
    • Itoh, N.1    Imagawa, A.2    Waguri, M.3
  • 22
    • 0030937468 scopus 로고    scopus 로고
    • Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse
    • O'Brien BA, Harmon BV, Cameron DP, Allan DJ (1997) Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse. Diabetes 46: 750-757
    • (1997) Diabetes , vol.46 , pp. 750-757
    • O'Brien, B.A.1    Harmon, B.V.2    Cameron, D.P.3    Allan, D.J.4
  • 23
    • 0027205529 scopus 로고
    • Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor
    • Coles HS, Burne JF, Raff MC (1993) Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor. Development 118: 777-784
    • (1993) Development , vol.118 , pp. 777-784
    • Coles, H.S.1    Burne, J.F.2    Raff, M.C.3
  • 24
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119: 493-501
    • (1992) J Cell Biol , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 25
    • 0029891535 scopus 로고    scopus 로고
    • Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: Possible involvement of common mediators in apoptotic and necrotic signal transductions
    • Shimizu S, Eguchi Y, Kamiike W et al. (1996) Retardation of chemical hypoxia-induced necrotic cell death by Bcl-2 and ICE inhibitors: possible involvement of common mediators in apoptotic and necrotic signal transductions. Oncogene 12:2045-2050
    • (1996) Oncogene , vol.12 , pp. 2045-2050
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3
  • 26
    • 0020466235 scopus 로고
    • Lymphocytic insulitis in a non-obese diabetic (NOD) strain of mice: An immunohistochemical and electron microscope investigation
    • Fujita T, Yui R, Kusumoto Y, Serizawa Y, Makino, Tochino Y (1982) Lymphocytic insulitis in a non-obese diabetic (NOD) strain of mice: an immunohistochemical and electron microscope investigation. Biomed Res 3: 429-443
    • (1982) Biomed Res , vol.3 , pp. 429-443
    • Fujita, T.1    Yui, R.2    Kusumoto, Y.3    Serizawa, Y.4    Makino5    Tochino, Y.6
  • 27
    • 0028987251 scopus 로고
    • Dynamics of β-cell mass in the growing rat pancreas. Estimation with a simple mathematical model
    • Finegood DT, Scaglia L, Bonner-Weir S (1995) Dynamics of β-cell mass in the growing rat pancreas. Estimation with a simple mathematical model. Diabetes 44: 249-256
    • (1995) Diabetes , vol.44 , pp. 249-256
    • Finegood, D.T.1    Scaglia, L.2    Bonner-Weir, S.3
  • 29
    • 0031684177 scopus 로고    scopus 로고
    • β-cell apoptosis in an accelerated model of autoimmune diabetes
    • Augstein P, Stephens LA, Allison J et al. (1998) β-cell apoptosis in an accelerated model of autoimmune diabetes. Mol Med
    • (1998) Mol Med
    • Augstein, P.1    Stephens, L.A.2    Allison, J.3
  • 30
    • 0025905091 scopus 로고
    • Characterization of pancreatic T lymphocytes associated with beta cell destruction in the non-obese diabetic (NOD) mouse
    • Kay TWH, Campbell IL, Harrison LC (1991) Characterization of pancreatic T lymphocytes associated with beta cell destruction in the non-obese diabetic (NOD) mouse. J Autoimmun 4: 263-276
    • (1991) J Autoimmun , vol.4 , pp. 263-276
    • Kay, T.W.H.1    Campbell, I.L.2    Harrison, L.C.3
  • 32
    • 0025104170 scopus 로고
    • Essential contribution of macrophages to islet cell destruction in vivo and in vitro
    • Kolb H, Burkart V, Appels B et al. (1990) Essential contribution of macrophages to islet cell destruction in vivo and in vitro. J Autoimmunity 3: 117-120
    • (1990) J Autoimmunity , vol.3 , pp. 117-120
    • Kolb, H.1    Burkart, V.2    Appels, B.3


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