Diabetic GK/Par rat β-cells are spontaneously protected against H 2O2-triggered apoptosis. A cAMP-dependent adaptive response

American Journal of Physiology - Endocrinology and Metabolism

Volumn 298, Issue 1, 2010, Pages

  Lacraz, Grégory ^a   Figeac, Florence ^a   Movassat, Jamileh ^a   Kassis, Nadim ^a   Portha, Bernard ^a  

^a UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

cell mass; Apoptosis; Cyclic adenosine monophosphate; Diabetic Goto Kakizaki rat; Reactive oxygen species; Replication

Indexed keywords

CYCLIC AMP; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL ISOLATION; CONTROLLED STUDY; DIABETES MELLITUS; GENE EXPRESSION; GENE SEQUENCE; GLUCOSE BLOOD LEVEL; GOTO KAKIZAKI RAT; IN VITRO STUDY; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; UPREGULATION;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CELL DIVISION; CELLS, CULTURED; CYCLIC AMP; CYCLIN D1; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; HEME OXYGENASE-1; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INSULIN-SECRETING CELLS; MALE; OXIDANTS; PROTO-ONCOGENE PROTEINS C-MYC; RATS; RATS, MUTANT STRAINS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 73649146161     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.90871.2008     Document Type: Article

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