-
2
-
-
33645220583
-
Drug-induced liver injury: Summary of a single topic clinical research conference
-
Watkins PB, Seeff LB,. Drug-induced liver injury: summary of a single topic clinical research conference. Hepatology 2006; 43: 618-31.
-
(2006)
Hepatology
, vol.43
, pp. 618-631
-
-
Watkins, P.B.1
Seeff, L.B.2
-
3
-
-
34247259568
-
Drug-induced liver injury
-
Abboud G, Kaplowitz N,. Drug-induced liver injury. Drug Saf 2007; 30: 277-94. (Pubitemid 46624528)
-
(2007)
Drug Safety
, vol.30
, Issue.4
, pp. 277-294
-
-
Abboud, G.1
Kaplowitz, N.2
-
4
-
-
84862822206
-
Drug-induced liver injury
-
Boyer T.D. Manns M.P. Sanyal A. eds. 6th ed. Philadelphia: Saunders-Elsevier
-
Bonkovsky HL, Shedlofsky SI, Jones DP, et al,. Drug-induced liver injury. In:, Boyer TD, Manns MP, Sanyal A, eds. Zakim and Boyer's Hepatology-A Textbook of Liver Disease, 6th ed. Philadelphia: Saunders-Elsevier, 2011.
-
(2011)
Zakim and Boyer's Hepatology - A Textbook of Liver Disease
-
-
Bonkovsky, H.L.1
Shedlofsky, S.I.2
Jones, D.P.3
-
5
-
-
0037126649
-
Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States
-
Ostapowicz G, Fontana RJ, Schiodt FV, et al,. Results of a prospective study of acute liver failure at 17 tertiary care centers in the United States. Ann Intern Med 2002; 137: 947-54. (Pubitemid 35440240)
-
(2002)
Annals of Internal Medicine
, vol.137
, Issue.12
, pp. 947-954
-
-
Ostapowicz, G.1
Fontana, R.J.2
Schioodt, F.V.3
Larson, A.4
Davern, T.J.5
Han, S.H.B.6
McCashland, T.M.7
Shakil, A.O.8
Hay, J.E.9
Hynan, L.10
Crippin, J.S.11
Blei, A.T.12
Samuel, G.13
Reisch, J.14
Lee, W.M.15
Santyanarayana, R.16
Caldwell, C.17
Shick, L.18
Bass, N.19
Rouillard, S.20
Atillasoy, E.21
Flamm, S.22
Benner, K.G.23
Rosen, H.R.24
Martin, P.25
Stribling, R.26
Schiff, E.R.27
Torres, M.B.28
Navarro, V.29
McGuire, B.30
Chung, R.31
Abraczinskas, D.32
Dienstag, J.33
more..
-
6
-
-
78649625452
-
Drug-induced acute liver failure: Results of a U.S. multicenter, prospective study
-
Reuben A, Koch DG, Lee WM,. Drug-induced acute liver failure: results of a U.S. multicenter, prospective study. Hepatology 2010; 52: 2065-76.
-
(2010)
Hepatology
, vol.52
, pp. 2065-2076
-
-
Reuben, A.1
Koch, D.G.2
Lee, W.M.3
-
7
-
-
77953210655
-
Drug-induced liver injury in clinical practice
-
Bjornsson E,. Drug-induced liver injury in clinical practice. Aliment Pharmacol Ther 2010; 32: 3-13.
-
(2010)
Aliment Pharmacol Ther
, vol.32
, pp. 3-13
-
-
Bjornsson, E.1
-
8
-
-
77952718055
-
Risk factors for idiosyncratic drug-induced liver injury
-
Chalasani N, Bjornsson E,. Risk factors for idiosyncratic drug-induced liver injury. Gastroenterology 2010; 138: 2246-59.
-
(2010)
Gastroenterology
, vol.138
, pp. 2246-2259
-
-
Chalasani, N.1
Bjornsson, E.2
-
9
-
-
79958175637
-
Drug-induced liver injury - Its pathophysiology and evolving diagnostic tools
-
Au JS, Navarro VJ, Rossi S,. Drug-induced liver injury-its pathophysiology and evolving diagnostic tools. Aliment Pharmacol Ther 2011; 34: 11-20.
-
(2011)
Aliment Pharmacol Ther
, vol.34
, pp. 11-20
-
-
Au, J.S.1
Navarro, V.J.2
Rossi, S.3
-
10
-
-
58149347349
-
Drug-Induced Liver Injury Network (DILIN) prospective study: Rationale, design and conduct
-
Fontana RJ, Watkins PB, Bonkovsky HL, et al,. Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct. Drug Saf 2009; 32: 55-68.
-
(2009)
Drug Saf
, vol.32
, pp. 55-68
-
-
Fontana, R.J.1
Watkins, P.B.2
Bonkovsky, H.L.3
-
11
-
-
77952702755
-
Causality assessment in drug-induced liver injury using a structured expert opinion process: Comparison to the Roussel-Uclaf causality assessment method
-
Rockey DC, Seeff LB, Rochon J, et al,. Causality assessment in drug-induced liver injury using a structured expert opinion process: comparison to the Roussel-Uclaf causality assessment method. Hepatology 2010; 51: 2117-26.
-
(2010)
Hepatology
, vol.51
, pp. 2117-2126
-
-
Rockey, D.C.1
Seeff, L.B.2
Rochon, J.3
-
12
-
-
57249086242
-
Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States
-
Chalasani N, Fontana RJ, Bonkovsky HL, et al,. Causes, clinical features, and outcomes from a prospective study of drug-induced liver injury in the United States. Gastroenterology 2008; 135: 1924-34.
-
(2008)
Gastroenterology
, vol.135
, pp. 1924-1934
-
-
Chalasani, N.1
Fontana, R.J.2
Bonkovsky, H.L.3
-
13
-
-
78649473610
-
Duloxetine hepatotoxicity: A case-series from the drug-induced liver injury network
-
Vuppalanchi R, Hayashi PH, Chalasani N, et al,. Duloxetine hepatotoxicity: a case-series from the drug-induced liver injury network. Aliment Pharmacol Ther 2010; 32: 1174-83.
-
(2010)
Aliment Pharmacol Ther
, vol.32
, pp. 1174-1183
-
-
Vuppalanchi, R.1
Hayashi, P.H.2
Chalasani, N.3
-
14
-
-
79957445248
-
Clinical and histopathologic features of fluoroquinolone-induced liver injury
-
Orman ES, Conjeevaram HS, Vuppalanchi R, et al,. Clinical and histopathologic features of fluoroquinolone-induced liver injury. Clin Gastroenterol Hepatol 2011; 9: 517-23.
-
(2011)
Clin Gastroenterol Hepatol
, vol.9
, pp. 517-523
-
-
Orman, E.S.1
Conjeevaram, H.S.2
Vuppalanchi, R.3
-
15
-
-
58149375807
-
Label-free mass spectrometry-based protein quantification technologies in proteomic analysis
-
Wang M, You J, Bemis KG, et al,. Label-free mass spectrometry-based protein quantification technologies in proteomic analysis. Brief Funct Genomic Proteomic 2008; 7: 329-39.
-
(2008)
Brief Funct Genomic Proteomic
, vol.7
, pp. 329-339
-
-
Wang, M.1
You, J.2
Bemis, K.G.3
-
16
-
-
73449090429
-
Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease
-
Bell LN, Theodorakis JL, Vuppalanchi R, et al,. Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease. Hepatology 2010; 51: 111-20.
-
(2010)
Hepatology
, vol.51
, pp. 111-120
-
-
Bell, L.N.1
Theodorakis, J.L.2
Vuppalanchi, R.3
-
17
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM,. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-54.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
18
-
-
4444313548
-
A simplified procedure for the reduction and alkylation of cysteine residues in proteins prior to proteolytic digestion and mass spectral analysis
-
DOI 10.1016/j.ab.2004.04.013, PII S0003269704003318
-
Hale JE, Butler JP, Gelfanova V, et al,. A simplified procedure for the reduction and alkylation of cysteine residues in proteins prior to proteolytic digestion and mass spectral analysis. Anal Biochem 2004; 333: 174-81. (Pubitemid 39209235)
-
(2004)
Analytical Biochemistry
, vol.333
, Issue.1
, pp. 174-181
-
-
Hale, J.E.1
Butler, J.P.2
Gelfanova, V.3
You, J.-S.4
Knierman, M.D.5
-
19
-
-
23944472666
-
Comprehensive label-free method for the relative quantification of proteins from biological samples
-
DOI 10.1021/pr050109b
-
Higgs RE, Knierman MD, Gelfanova V, et al,. Comprehensive label-free method for the relative quantification of proteins from biological samples. J Proteome Res 2005; 4: 1442-50. (Pubitemid 41208703)
-
(2005)
Journal of Proteome Research
, vol.4
, Issue.4
, pp. 1442-1450
-
-
Higgs, R.E.1
Knierman, M.D.2
Gelfanova, V.3
Butler, J.P.4
Hale, J.E.5
-
20
-
-
3142702204
-
TANDEM: Matching proteins with tandem mass spectra
-
DOI 10.1093/bioinformatics/bth092
-
Craig R, Beavis RC,. TANDEM: matching proteins with tandem mass spectra. Bioinformatics 2004; 20: 1466-7. (Pubitemid 38931421)
-
(2004)
Bioinformatics
, vol.20
, Issue.9
, pp. 1466-1467
-
-
Craig, R.1
Beavis, R.C.2
-
21
-
-
0000857494
-
An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database
-
Eng J, McCormack A, Yates RR,. An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. J Am Soc Mass Spectrom 1994; 5: 976-89.
-
(1994)
J Am Soc Mass Spectrom
, vol.5
, pp. 976-989
-
-
Eng, J.1
McCormack, A.2
Yates, R.R.3
-
22
-
-
34249316472
-
Estimating the statistical significance of peptide identifications from shotgun proteomics experiments
-
DOI 10.1021/pr0605320
-
Higgs RE, Knierman MD, Freeman AB, et al,. Estimating the statistical significance of peptide identifications from shotgun proteomics experiments. J Proteome Res 2007; 6: 1758-67. (Pubitemid 46814500)
-
(2007)
Journal of Proteome Research
, vol.6
, Issue.5
, pp. 1758-1767
-
-
Higgs, R.E.1
Knierman, M.D.2
Freeman, A.B.3
Gelbert, L.M.4
Patil, S.T.5
Hale, J.E.6
-
23
-
-
0037316303
-
A comparison of normalization methods for high density oligonucleotide array data based on variance and bias
-
DOI 10.1093/bioinformatics/19.2.185
-
Bolstad BM, Irizarry RA, Astrand M, et al,. A comparison of normalization methods for high density oligonucleotide array data based on variance and bias. Bioinformatics 2003; 19: 185-93. (Pubitemid 36181903)
-
(2003)
Bioinformatics
, vol.19
, Issue.2
, pp. 185-193
-
-
Bolstad, B.M.1
Irizarry, R.A.2
Astrand, M.3
Speed, T.P.4
-
24
-
-
79953692673
-
Mechanisms of drug-induced liver injury: From bedside to bench
-
Tujios S, Fontana RJ,. Mechanisms of drug-induced liver injury: from bedside to bench. Nat Rev Gastroenterol Hepatol 2011; 8: 202-11.
-
(2011)
Nat Rev Gastroenterol Hepatol
, vol.8
, pp. 202-211
-
-
Tujios, S.1
Fontana, R.J.2
-
25
-
-
78650561076
-
Application of toxicogenomics in hepatic systems toxicology for risk assessment: Acetaminophen as a case study
-
Kienhuis AS, Bessems JG, Pennings JL, et al,. Application of toxicogenomics in hepatic systems toxicology for risk assessment: acetaminophen as a case study. Toxicol Appl Pharmacol 2011; 250: 96-107.
-
(2011)
Toxicol Appl Pharmacol
, vol.250
, pp. 96-107
-
-
Kienhuis, A.S.1
Bessems, J.G.2
Pennings, J.L.3
-
26
-
-
79953713653
-
The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury
-
Ellinger-Ziegelbauer H, Adler M, Amberg A, et al,. The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury. Toxicol Appl Pharmacol 2011; 252: 97-111.
-
(2011)
Toxicol Appl Pharmacol
, vol.252
, pp. 97-111
-
-
Ellinger-Ziegelbauer, H.1
Adler, M.2
Amberg, A.3
-
27
-
-
78149403133
-
Analysis of secreted proteins as an in vitro model for discovery of liver toxicity markers
-
Lewis JA, Dennis WE, Hadix J, et al,. Analysis of secreted proteins as an in vitro model for discovery of liver toxicity markers. J Proteome Res 2010; 9: 5794-802.
-
(2010)
J Proteome Res
, vol.9
, pp. 5794-5802
-
-
Lewis, J.A.1
Dennis, W.E.2
Hadix, J.3
-
28
-
-
77956305956
-
Potential implications for monitoring serum bile acid profiles in circulation with serum proteome for carbon tetrachloride-induced liver injury/regeneration model in mice
-
Shimada T, Nakanishi T, Toyama A, et al,. Potential implications for monitoring serum bile acid profiles in circulation with serum proteome for carbon tetrachloride-induced liver injury/regeneration model in mice. J Proteome Res 2010; 9: 4490-500.
-
(2010)
J Proteome Res
, vol.9
, pp. 4490-4500
-
-
Shimada, T.1
Nakanishi, T.2
Toyama, A.3
-
29
-
-
77955593674
-
Plasma and liver proteomic analysis of 3Z-3-[(1H-pyrrol-2-yl)- methylidene]-1-(1-piperidinylmethyl)-1,3-2H-indol-2-one-induced hepatotoxicity in Wistar rats
-
Wang Y, Yang B, Wu C, et al,. Plasma and liver proteomic analysis of 3Z-3-[(1H-pyrrol-2-yl)-methylidene]-1-(1-piperidinylmethyl)-1, 3-2H-indol-2-one-induced hepatotoxicity in Wistar rats. Proteomics 2010; 10: 2927-41.
-
(2010)
Proteomics
, vol.10
, pp. 2927-2941
-
-
Wang, Y.1
Yang, B.2
Wu, C.3
-
30
-
-
72949092649
-
A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran
-
Andersson U, Lindberg J, Wang S, et al,. A systems biology approach to understanding elevated serum alanine transaminase levels in a clinical trial with ximelagatran. Biomarkers 2009; 14: 572-86.
-
(2009)
Biomarkers
, vol.14
, pp. 572-586
-
-
Andersson, U.1
Lindberg, J.2
Wang, S.3
-
31
-
-
34447134883
-
A proteomic method for analysis of CYP450s protein expression changes in carbon tetrachloride induced male rat liver microsomes
-
DOI 10.1016/j.tox.2007.04.015, PII S0300483X07002168
-
Jia N, Liu X, Wen J, et al,. A proteomic method for analysis of CYP450s protein expression changes in carbon tetrachloride induced male rat liver microsomes. Toxicology 2007; 237: 1-11. (Pubitemid 47033948)
-
(2007)
Toxicology
, vol.237
, Issue.1-3
, pp. 1-11
-
-
Jia, N.1
Liu, X.2
Wen, J.3
Qian, L.4
Qian, X.5
Wu, Y.6
Fan, G.7
-
32
-
-
33745823913
-
Systems toxicology: Integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat
-
DOI 10.1021/pr0503376
-
Craig A, Sidaway J, Holmes E, et al,. Systems toxicology: integrated genomic, proteomic and metabonomic analysis of methapyrilene induced hepatotoxicity in the rat. J Proteome Res 2006; 5: 1586-601. (Pubitemid 44036133)
-
(2006)
Journal of Proteome Research
, vol.5
, Issue.7
, pp. 1586-1601
-
-
Craig, A.1
Sidaway, J.2
Holmes, E.3
Orton, T.4
Jackson, D.5
Rowlinson, R.6
Nickson, J.7
Tonge, R.8
Wilson, I.9
Nicholson, J.10
-
33
-
-
33745945069
-
Alterations in the rat serum proteome during liver injury from acetaminophen exposure
-
DOI 10.1124/jpet.106.102681
-
Merrick BA, Bruno ME, Madenspacher JH, et al,. Alterations in the rat serum proteome during liver injury from acetaminophen exposure. J Pharmacol Exp Ther 2006; 318: 792-802. (Pubitemid 44061253)
-
(2006)
Journal of Pharmacology and Experimental Therapeutics
, vol.318
, Issue.2
, pp. 792-802
-
-
Merrick, B.A.1
Bruno, M.E.2
Madenspacher, J.H.3
Wetmore, B.A.4
Foley, J.5
Pieper, R.6
Zhao, M.7
Makusky, A.J.8
McGrath, A.M.9
Zhou, J.X.10
Taylor, J.11
Tomer, K.B.12
-
34
-
-
29044450622
-
Altered protein expression and protein nitration pattern during D-galactosamine-induced cell death in human hepatocytes: A proteomic analysis
-
DOI 10.1111/j.1478-3231.2005.01172.x
-
Rodriguez-Ariza A, Lopez-Sanchez LM, Gonzalez R, et al,. Altered protein expression and protein nitration pattern during d-galactosamine-induced cell death in human hepatocytes: a proteomic analysis. Liver Int 2005; 25: 1259-69. (Pubitemid 41786701)
-
(2005)
Liver International
, vol.25
, Issue.6
, pp. 1259-1269
-
-
Rodriguez-Ariza, A.1
Lopez-Sanchez, L.M.2
Gonzalez, R.3
Corrales, F.J.4
Lopez, P.5
Bernardos, A.6
Muntane, J.7
-
35
-
-
25444517040
-
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy
-
DOI 10.1373/clinchem.2005.049908
-
Amacher DE, Adler R, Herath A, et al,. Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. Clin Chem 2005; 51: 1796-803. (Pubitemid 41368169)
-
(2005)
Clinical Chemistry
, vol.51
, Issue.10
, pp. 1796-1803
-
-
Amacher, D.E.1
Adler, R.2
Herath, A.3
Townsend, R.R.4
-
36
-
-
21144438395
-
Proteomic identification of potential susceptibility factors in drug-induced liver disease
-
DOI 10.1021/tx050011b
-
Welch KD, Wen B, Goodlett DR, et al,. Proteomic identification of potential susceptibility factors in drug-induced liver disease. Chem Res Toxicol 2005; 18: 924-33. (Pubitemid 40880881)
-
(2005)
Chemical Research in Toxicology
, vol.18
, Issue.6
, pp. 924-933
-
-
Welch, K.D.1
Wen, B.2
Goodlett, D.R.3
Yi, E.C.4
Lee, H.5
Reilly, T.P.6
Nelson, S.D.7
Pohl, L.R.8
-
37
-
-
4644269948
-
Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers
-
DOI 10.1080/13547500410001728408
-
Kleno TG, Kiehr B, Baunsgaard D, et al,. Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers. Biomarkers 2004; 9: 116-38. (Pubitemid 39268768)
-
(2004)
Biomarkers
, vol.9
, Issue.2
, pp. 116-138
-
-
Kleno, T.G.1
Kiehr, B.2
Baunsgaard, D.3
Sidelmann, U.G.4
-
38
-
-
77955919042
-
The application of metabonomics to predict drug-induced liver injury
-
O'Connell TM, Watkins PB,. The application of metabonomics to predict drug-induced liver injury. Clin Pharmacol Ther 2010; 88: 394-9.
-
(2010)
Clin Pharmacol Ther
, vol.88
, pp. 394-399
-
-
O'Connell, T.M.1
Watkins, P.B.2
-
39
-
-
77950357495
-
Use of transcriptomics in understanding mechanisms of drug-induced toxicity
-
Cui Y, Paules RS,. Use of transcriptomics in understanding mechanisms of drug-induced toxicity. Pharmacogenomics 2010; 11: 573-85.
-
(2010)
Pharmacogenomics
, vol.11
, pp. 573-585
-
-
Cui, Y.1
Paules, R.S.2
-
41
-
-
27444439653
-
Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction
-
DOI 10.1016/j.tox.2005.07.012, PII S0300483X05003380
-
Maniratanachote R, Shibata A, Kaneko S, et al,. Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction. Toxicology 2005; 216: 15-23. (Pubitemid 41531254)
-
(2005)
Toxicology
, vol.216
, Issue.1
, pp. 15-23
-
-
Maniratanachote, R.1
Shibata, A.2
Kaneko, S.3
Yamamori, I.4
Wakasugi, T.5
Sawazaki, T.6
Katoh, K.7
Tokudome, S.8
Nakajima, M.9
Yokoi, T.10
-
42
-
-
77957667161
-
The potential of cytokines as safety biomarkers for drug-induced liver injury
-
Laverty HG, Antoine DJ, Benson C, et al,. The potential of cytokines as safety biomarkers for drug-induced liver injury. Eur J Clin Pharmacol 2010; 66: 961-76.
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 961-976
-
-
Laverty, H.G.1
Antoine, D.J.2
Benson, C.3
-
43
-
-
65349093477
-
Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: Potential involvement of oxysterols
-
Ferre N, Martinez-Clemente M, Lopez-Parra M, et al,. Increased susceptibility to exacerbated liver injury in hypercholesterolemic ApoE-deficient mice: potential involvement of oxysterols. Am J Physiol Gastrointest Liver Physiol 2009; 296: G553-62.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.296
-
-
Ferre, N.1
Martinez-Clemente, M.2
Lopez-Parra, M.3
|