Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers

Biomarkers

Volumn 9, Issue 2, 2004, Pages 116-138

  Kleno T G ^a   Kiehr, B ^a   Baunsgaard, D ^a   Sidelmann, U G ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

Genomics; Glucose metabolism; Hydrazine; Lipid metabolism; Metabonomics; Oxidative stress; Proteomics

Indexed keywords

BIOLOGICAL MARKER; COMPLEMENTARY DNA; GLUCOSE; HYDRAZINE; LIPID; MESSENGER RNA; PROTEIN;

AMINO ACID SEQUENCE; ANIMAL TISSUE; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENE MUTATION; GENOMICS; GLUCOSE METABOLISM; LIPID METABOLISM; LIVER TOXICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RAT STRAIN; REVIEW; RNA EXTRACTION; RNA FINGERPRINTING; RNA TRANSCRIPTION; TWO DIMENSIONAL GEL ELECTROPHORESIS; UNINDEXED SEQUENCE;

ANIMALS; BIOLOGICAL MARKERS; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION PROFILING; GENOMICS; GLUCOSE; HYDRAZINES; LIPID METABOLISM; LIVER; LIVER DISEASES; MALE; METABOLISM; OXIDATIVE STRESS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

ANIMALIA;

EID: 4644269948     PISSN: 1354750X     EISSN: None     Source Type: Journal    
DOI: 10.1080/13547500410001728408     Document Type: Review

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