메뉴 건너뛰기




Volumn 45, Issue 2, 2012, Pages 379-387

Sortilin and SorLA regulate neuronal sorting of trophic and dementia-linked proteins

Author keywords

Alzheimer's disease; APP; BDNF; Progranulin; SorLA; Sortilin; Trk

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CELL PROTEIN; NEUROTROPHIC FACTOR; NEUROTROPHIN; NEUROTROPHIN RECEPTOR; PROGRANULIN; PROTEIN SORLA; SORTILIN; UNCLASSIFIED DRUG;

EID: 84862703993     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-012-8236-2     Document Type: Review
Times cited : (20)

References (91)
  • 1
    • 56549111118 scopus 로고    scopus 로고
    • VPS10P-domain receptors - Regulators of neuronal viability and function
    • Willnow TE, Petersen CM, Nykjaer A (2008) VPS10P-domain receptors - regulators of neuronal viability and function. Nat Rev Neurosci 9:899-909
    • (2008) Nat Rev Neurosci , vol.9 , pp. 899-909
    • Willnow, T.E.1    Petersen, C.M.2    Nykjaer, A.3
  • 5
    • 33645763676 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members
    • Hermey G, Sjøgaard SS, Petersen CM, Nykjaer A, Gliemann J (2006) Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members. Biochem J 395:285-293
    • (2006) Biochem J , vol.395 , pp. 285-293
    • Hermey, G.1    Sjøgaard, S.S.2    Petersen, C.M.3    Nykjaer, A.4    Gliemann, J.5
  • 15
    • 33748313351 scopus 로고    scopus 로고
    • Retrograde transport from endosomes to the trans-Golgi network
    • Bonifacino JS, Rojas R (2006) Retrograde transport from endosomes to the trans-Golgi network. Nat Rev Mol Cell Biol 7:568-579
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 568-579
    • Bonifacino, J.S.1    Rojas, R.2
  • 17
    • 0033081042 scopus 로고    scopus 로고
    • Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
    • Bibel M, Hoppe E, Barde YA (1999) Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR. EMBO J 18:616-622
    • (1999) EMBO J , vol.18 , pp. 616-622
    • Bibel, M.1    Hoppe, E.2    Barde, Y.A.3
  • 18
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signalling pathways
    • Chao MV (2003) Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci 4:299-309
    • (2003) Nat Rev Neurosci , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 20
    • 0035976524 scopus 로고    scopus 로고
    • Regulation of cell survival by secreted proneurotrophins
    • Lee R, Kermani P, Teng KK, Hempstead BL (2001) Regulation of cell survival by secreted proneurotrophins. Science 294:1945-1948
    • (2001) Science , vol.294 , pp. 1945-1948
    • Lee, R.1    Kermani, P.2    Teng, K.K.3    Hempstead, B.L.4
  • 26
    • 34548336779 scopus 로고    scopus 로고
    • New insights into BDNF function in depression and anxiety
    • Martinowich K, Manji H, Lu B (2007) New insights into BDNF function in depression and anxiety. Nat Neurosci 10:1089-1093
    • (2007) Nat Neurosci , vol.10 , pp. 1089-1093
    • Martinowich, K.1    Manji, H.2    Lu, B.3
  • 28
    • 14644390283 scopus 로고    scopus 로고
    • Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo
    • Pattabiraman PP, Tropea D, Chiaruttini C, Tongiorgi E, Cattaneo A, Domenici L (2005) Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo. Mol Cell Neurosci 28:556-570
    • (2005) Mol Cell Neurosci , vol.28 , pp. 556-570
    • Pattabiraman, P.P.1    Tropea, D.2    Chiaruttini, C.3    Tongiorgi, E.4    Cattaneo, A.5    Domenici, L.6
  • 29
    • 0141894133 scopus 로고    scopus 로고
    • Neuronal polarity and trafficking
    • Horton AC, Ehlers MD (2003) Neuronal polarity and trafficking. Neuron 40:277-295
    • (2003) Neuron , vol.40 , pp. 277-295
    • Horton, A.C.1    Ehlers, M.D.2
  • 31
    • 12344328770 scopus 로고    scopus 로고
    • Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e
    • Lou H, Kim S-K, Zaitsev E, Snell CR, Lu B, Loh YP (2005) Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e. Neuron 45:245-255
    • (2005) Neuron , vol.45 , pp. 245-255
    • Lou, H.1    Kim, S.-K.2    Zaitsev, E.3    Snell, C.R.4    Lu, B.5    Loh, Y.P.6
  • 34
    • 77955431930 scopus 로고    scopus 로고
    • The BDNF Val66Met polymorphism and anxiety: Support for animal knock-in studies from a genetic association study in humans
    • Montag C, Basten U, Stelzel C, Fiebach CJ, Reuter M (2010) The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans. Psychiatry Res 179:86-90
    • (2010) Psychiatry Res , vol.179 , pp. 86-90
    • Montag, C.1    Basten, U.2    Stelzel, C.3    Fiebach, C.J.4    Reuter, M.5
  • 35
    • 78149267659 scopus 로고    scopus 로고
    • Variant brain-derived neurotrophic factor Val66Met endophenotypes: Implications for posttraumatic stress disorder
    • Frielingsdorf H, Bath KG, Soliman F, Difede J, Casey BJ, Lee FS (2010) Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder. Ann N Y Acad Sci 1208:150-157
    • (2010) Ann N Y Acad Sci , vol.1208 , pp. 150-157
    • Frielingsdorf, H.1    Bath, K.G.2    Soliman, F.3    Difede, J.4    Casey, B.J.5    Lee, F.S.6
  • 36
    • 77954421126 scopus 로고    scopus 로고
    • The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus
    • Ninan I, Bath KG, Dagar K, Perez-Castro R, Plummer MR, Lee FS, Chao MV (2010) The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. J Neurosci 30:8866-8870
    • (2010) J Neurosci , vol.30 , pp. 8866-8870
    • Ninan, I.1    Bath, K.G.2    Dagar, K.3    Perez-Castro, R.4    Plummer, M.R.5    Lee, F.S.6    Chao, M.V.7
  • 39
    • 33645642673 scopus 로고    scopus 로고
    • Interaction of Huntingtin-associated protein-1 with kinesin light chain: Implications in intracellular trafficking in neurons
    • McGuire JR, Rong J, Li S-H, Li X-J (2006) Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. J Biol Chem 281:3552-3559
    • (2006) J Biol Chem , vol.281 , pp. 3552-3559
    • McGuire, J.R.1    Rong, J.2    Li, S.-H.3    Li, X.-J.4
  • 40
    • 79955507013 scopus 로고    scopus 로고
    • Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation and processing
    • Yang M, Lim Y, Li X, Zhong J-H, Zhou X-F (2011) Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation and processing. J Biol Chem 286:16272-16284
    • (2011) J Biol Chem , vol.286 , pp. 16272-16284
    • Yang, M.1    Lim, Y.2    Li, X.3    Zhong, J.-H.4    Zhou, X.-F.5
  • 41
    • 80051940841 scopus 로고    scopus 로고
    • Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation
    • Evans SF, Irmady K, Ostrow K, Kim T, Nykjaer A, Saftig P, Blobel C, Hempstead BL (2011) Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. J Biol Chem 286:29556-29567
    • (2011) J Biol Chem , vol.286 , pp. 29556-29567
    • Evans, S.F.1    Irmady, K.2    Ostrow, K.3    Kim, T.4    Nykjaer, A.5    Saftig, P.6    Blobel, C.7    Hempstead, B.L.8
  • 43
    • 33747051514 scopus 로고    scopus 로고
    • Interaction of survival and death signaling in basal forebrain neurons: Roles of neurotrophins and proneurotrophins
    • Volosin M, Song W, Almeida RD, Kaplan DR, Hempstead BL, Friedman WJ (2006) Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. J Neurosci 26:7756-7766
    • (2006) J Neurosci , vol.26 , pp. 7756-7766
    • Volosin, M.1    Song, W.2    Almeida, R.D.3    Kaplan, D.R.4    Hempstead, B.L.5    Friedman, W.J.6
  • 46
    • 36448986390 scopus 로고    scopus 로고
    • Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia
    • Wei Y, Wang N, Lu Q, Zhang N, Zheng D, Li J (2007) Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia. Neurosci Lett 429:169-174
    • (2007) Neurosci Lett , vol.429 , pp. 169-174
    • Wei, Y.1    Wang, N.2    Lu, Q.3    Zhang, N.4    Zheng, D.5    Li, J.6
  • 47
    • 43049146531 scopus 로고    scopus 로고
    • Up-regulation of pro-nerve growth factor, neurotrophin receptor p75, and sortilin is associated with retrovirus-induced spongiform encephalomyelopathy
    • Stoica G, Lungu G, Kim H-T, Wong PKY (2008) Up-regulation of pro-nerve growth factor, neurotrophin receptor p75, and sortilin is associated with retrovirus-induced spongiform encephalomyelopathy. Brain Res 1208:204-216
    • (2008) Brain Res , vol.1208 , pp. 204-216
    • Stoica, G.1    Lungu, G.2    Kim, H.-T.3    Wong, P.K.Y.4
  • 48
    • 33750950147 scopus 로고    scopus 로고
    • The dynamic distribution of TrkB receptors before, during, and after synapse formation between cortical neurons
    • Gomes RA, Hampton C, El-Sabeawy F, Sabo SL, McAllister AK (2006) The dynamic distribution of TrkB receptors before, during, and after synapse formation between cortical neurons. J Neurosci 26:11487-11500
    • (2006) J Neurosci , vol.26 , pp. 11487-11500
    • Gomes, R.A.1    Hampton, C.2    El-Sabeawy, F.3    Sabo, S.L.4    McAllister, A.K.5
  • 49
  • 50
    • 0028291238 scopus 로고
    • Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents
    • Ernfors P, Lee KF, Kucera J, Jaenisch R (1994) Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77:503-512
    • (1994) Cell , vol.77 , pp. 503-512
    • Ernfors, P.1    Lee, K.F.2    Kucera, J.3    Jaenisch, R.4
  • 51
    • 0027491104 scopus 로고
    • Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death
    • Klein R, Smeyne RJ, Wurst W, Long LK, Auerbach BA, Joyner AL, Barbacid M (1993) Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75:113-122
    • (1993) Cell , vol.75 , pp. 113-122
    • Klein, R.1    Smeyne, R.J.2    Wurst, W.3    Long, L.K.4    Auerbach, B.A.5    Joyner, A.L.6    Barbacid, M.7
  • 52
    • 0029558477 scopus 로고
    • Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons
    • Minichiello L, Piehl F, Vazquez E, Schimmang T, Hökfelt T, Represa J, Klein R (1995) Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons. Development 121:4067-4075
    • (1995) Development , vol.121 , pp. 4067-4075
    • Minichiello, L.1    Piehl, F.2    Vazquez, E.3    Schimmang, T.4    Hökfelt, T.5    Represa, J.6    Klein, R.7
  • 53
    • 0028223015 scopus 로고
    • Clinical and neuropathological criteria for frontotemporal dementia
    • Englund B et al (1994) Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry 57:416-418
    • (1994) J Neurol Neurosurg Psychiatry , vol.57 , pp. 416-418
    • Englund, B.1
  • 56
    • 84860389481 scopus 로고    scopus 로고
    • Progranulin and TDP-43: Mechanistic links and future directions
    • Kumar-Singh S (2011) Progranulin and TDP-43: Mechanistic links and future directions. J Mol Neurosci 45:561-573
    • (2011) J Mol Neurosci , vol.45 , pp. 561-573
    • Kumar-Singh, S.1
  • 61
    • 77956850818 scopus 로고    scopus 로고
    • TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
    • Mackenzie IR, Rademakers R, Neumann M (2010) TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 9:995-1007
    • (2010) Lancet Neurol , vol.9 , pp. 995-1007
    • Mackenzie, I.R.1    Rademakers, R.2    Neumann, M.3
  • 64
    • 80855130704 scopus 로고    scopus 로고
    • Potential mechanisms of progranulin-deficient FTLD
    • Ward ME, Miller BL (2011) Potential mechanisms of progranulin-deficient FTLD. J Mol Neurosci 45:574-582
    • (2011) J Mol Neurosci , vol.45 , pp. 574-582
    • Ward, M.E.1    Miller, B.L.2
  • 67
    • 79958831842 scopus 로고    scopus 로고
    • C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking
    • Zheng Y, Brady OA, Meng PS, Mao Y, Hu F (2011) C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking. PLoS One 6:e21023
    • (2011) PLoS One , vol.6
    • Zheng, Y.1    Brady, O.A.2    Meng, P.S.3    Mao, Y.4    Hu, F.5
  • 68
    • 77954578417 scopus 로고    scopus 로고
    • Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging
    • Ahmed Z, Sheng H, Xu YF, Lin WL, Innes AE, Gass J, Yu X, Wuertzer CA, Hou H, Chiba S et al (2010) Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging. Am J Pathol 177:311-324
    • (2010) Am J Pathol , vol.177 , pp. 311-324
    • Ahmed, Z.1    Sheng, H.2    Xu, Y.F.3    Lin, W.L.4    Innes, A.E.5    Gass, J.6    Yu, X.7    Wuertzer, C.A.8    Hou, H.9    Chiba, S.10
  • 70
    • 33847662852 scopus 로고    scopus 로고
    • Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
    • Haass C, Selkoe DJ (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8:101-112
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 101-112
    • Haass, C.1    Selkoe, D.J.2
  • 71
    • 33749042749 scopus 로고    scopus 로고
    • Sorting through the cell biology of Alzheimer's disease: Intracellular pathways to pathogenesis
    • Small SA, Gandy S (2006) Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis. Neuron 52:15-31
    • (2006) Neuron , vol.52 , pp. 15-31
    • Small, S.A.1    Gandy, S.2
  • 79
    • 63649164073 scopus 로고    scopus 로고
    • Trafficking, a key player in regulated intramembrane proteolysis
    • Sannerud R, Annaert W (2009) Trafficking, a key player in regulated intramembrane proteolysis. Semin Cell Dev Biol 20:183-190
    • (2009) Semin Cell Dev Biol , vol.20 , pp. 183-190
    • Sannerud, R.1    Annaert, W.2
  • 81
    • 32544435097 scopus 로고    scopus 로고
    • The Lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments
    • Offe K, Dodson SE, Shoemaker JT, Fritz JJ, Gearing M, Levey AI, Lah JJ (2006) The Lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments. J Neurosci 26:1596-1603
    • (2006) J Neurosci , vol.26 , pp. 1596-1603
    • Offe, K.1    Dodson, S.E.2    Shoemaker, J.T.3    Fritz, J.J.4    Gearing, M.5    Levey, A.I.6    Lah, J.J.7
  • 82
    • 36349025159 scopus 로고    scopus 로고
    • SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1
    • Schmidt V, Sporbert A, Rohe M, Reimer T, Rehm A, Andersen OM, Willnow TE (2007) SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1. J Biol Chem 282:32956-32964
    • (2007) J Biol Chem , vol.282 , pp. 32956-32964
    • Schmidt, V.1    Sporbert, A.2    Rohe, M.3    Reimer, T.4    Rehm, A.5    Andersen, O.M.6    Willnow, T.E.7
  • 83
    • 58149373433 scopus 로고    scopus 로고
    • Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: Evidence for a proximal role in Alzheimer's disease
    • Dodson SE, Andersen OM, Karmali V, Fritz JJ, Cheng D, Peng J, Levey AI, Willnow TE, Lah JJ (2008) Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. J Neurosci 28:12877-12886
    • (2008) J Neurosci , vol.28 , pp. 12877-12886
    • Dodson, S.E.1    Andersen, O.M.2    Karmali, V.3    Fritz, J.J.4    Cheng, D.5    Peng, J.6    Levey, A.I.7    Willnow, T.E.8    Lah, J.J.9
  • 84
    • 47249144294 scopus 로고    scopus 로고
    • Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis
    • Rohe M, Carlo A-S, Breyhan H, Sporbert A, Militz D, Schmidt V, Wozny C, Harmeier A, Erdmann B, Bales KR et al (2008) Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis. J Biol Chem 283:14826-14834
    • (2008) J Biol Chem , vol.283 , pp. 14826-14834
    • Rohe, M.1    Carlo, A.-S.2    Breyhan, H.3    Sporbert, A.4    Militz, D.5    Schmidt, V.6    Wozny, C.7    Harmeier, A.8    Erdmann, B.9    Bales, K.R.10
  • 85
    • 33749348509 scopus 로고    scopus 로고
    • A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking
    • Scott GK, Fei H, Thomas L, Medigeshi GR, Thomas G (2006) A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking. EMBO J 25:4423-4435
    • (2006) EMBO J , vol.25 , pp. 4423-4435
    • Scott, G.K.1    Fei, H.2    Thomas, L.3    Medigeshi, G.R.4    Thomas, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.