-
1
-
-
56549111118
-
VPS10P-domain receptors - Regulators of neuronal viability and function
-
Willnow TE, Petersen CM, Nykjaer A (2008) VPS10P-domain receptors - regulators of neuronal viability and function. Nat Rev Neurosci 9:899-909
-
(2008)
Nat Rev Neurosci
, vol.9
, pp. 899-909
-
-
Willnow, T.E.1
Petersen, C.M.2
Nykjaer, A.3
-
2
-
-
58149267525
-
Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain
-
Quistgaard EM, Madsen P, Grøftehauge MK, Nissen P, Petersen CM, Thirup SS (2009) Ligands bind to Sortilin in the tunnel of a ten-bladed beta-propeller domain. Nat Struct Mol Biol 16:96-98
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 96-98
-
-
Quistgaard, E.M.1
Madsen, P.2
Grøftehauge, M.K.3
Nissen, P.4
Petersen, C.M.5
Thirup, S.S.6
-
3
-
-
33744965388
-
SorLA signaling by regulated intramembrane proteolysis
-
Böhm C, Seibel NM, Henkel B, Steiner H, Haass C, Hampe W (2006) SorLA signaling by regulated intramembrane proteolysis. J Biol Chem 281:14547-14553
-
(2006)
J Biol Chem
, vol.281
, pp. 14547-14553
-
-
Böhm, C.1
Seibel, N.M.2
Henkel, B.3
Steiner, H.4
Haass, C.5
Hampe, W.6
-
4
-
-
0033081041
-
Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding
-
Munck Petersen C, Nielsen MS, Jacobsen C, Tauris J, Jacobsen L, Gliemann J, Moestrup SK, Madsen P (1999) Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand binding. EMBO J 18:595-604
-
(1999)
EMBO J
, vol.18
, pp. 595-604
-
-
Munck Petersen, C.1
Nielsen, M.S.2
Jacobsen, C.3
Tauris, J.4
Jacobsen, L.5
Gliemann, J.6
Moestrup, S.K.7
Madsen, P.8
-
5
-
-
33645763676
-
Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members
-
Hermey G, Sjøgaard SS, Petersen CM, Nykjaer A, Gliemann J (2006) Tumour necrosis factor alpha-converting enzyme mediates ectodomain shedding of Vps10p-domain receptor family members. Biochem J 395:285-293
-
(2006)
Biochem J
, vol.395
, pp. 285-293
-
-
Hermey, G.1
Sjøgaard, S.S.2
Petersen, C.M.3
Nykjaer, A.4
Gliemann, J.5
-
6
-
-
34748899949
-
Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA
-
Nielsen MS, Gustafsen C, Madsen P, Nyengaard JR, Hermey G, Bakke O, Mari M, Schu P, Pohlmann R, Dennes A et al (2007) Sorting by the cytoplasmic domain of the amyloid precursor protein binding receptor SorLA. Mol Cell Biol 27:6842-6851
-
(2007)
Mol Cell Biol
, vol.27
, pp. 6842-6851
-
-
Nielsen, M.S.1
Gustafsen, C.2
Madsen, P.3
Nyengaard, J.R.4
Hermey, G.5
Bakke, O.6
Mari, M.7
Schu, P.8
Pohlmann, R.9
Dennes, A.10
-
7
-
-
0035341211
-
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein
-
Nielsen MS, Madsen P, Christensen EI, Nykjaer A, Gliemann J, Kasper D, Pohlmann R, Petersen CM (2001) The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting protein. EMBO J 20:2180-2190
-
(2001)
EMBO J
, vol.20
, pp. 2180-2190
-
-
Nielsen, M.S.1
Madsen, P.2
Christensen, E.I.3
Nykjaer, A.4
Gliemann, J.5
Kasper, D.6
Pohlmann, R.7
Petersen, C.M.8
-
8
-
-
0035933822
-
Activation and functional characterization of the mosaic receptor SorLA/LR11
-
Jacobsen L, Madsen P, Jacobsen C, Nielsen MS, Gliemann J, Petersen CM (2001) Activation and functional characterization of the mosaic receptor SorLA/LR11. J Biol Chem 276:22788-22796
-
(2001)
J Biol Chem
, vol.276
, pp. 22788-22796
-
-
Jacobsen, L.1
Madsen, P.2
Jacobsen, C.3
Nielsen, M.S.4
Gliemann, J.5
Petersen, C.M.6
-
9
-
-
0037762557
-
Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system
-
Sarret P, Krzywkowski P, Segal L, Nielsen MS, Petersen CM, Mazella J, Stroh T, Beaudet A (2003) Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system. J Comp Neurol 461:483-505
-
(2003)
J Comp Neurol
, vol.461
, pp. 483-505
-
-
Sarret, P.1
Krzywkowski, P.2
Segal, L.3
Nielsen, M.S.4
Petersen, C.M.5
Mazella, J.6
Stroh, T.7
Beaudet, A.8
-
10
-
-
0029962505
-
Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein
-
Jacobsen L, Madsen P, Moestrup SK, Lund AH, Tommerup N, Nykjaer A, Sottrup-Jensen L, Gliemann J, Petersen CM (1996) Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein. J Biol Chem 271:31379-31383
-
(1996)
J Biol Chem
, vol.271
, pp. 31379-31383
-
-
Jacobsen, L.1
Madsen, P.2
Moestrup, S.K.3
Lund, A.H.4
Tommerup, N.5
Nykjaer, A.6
Sottrup-Jensen, L.7
Gliemann, J.8
Petersen, C.M.9
-
11
-
-
78650678063
-
Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling
-
Vaegter CB, Jansen P, Fjorback AW, Glerup S, Skeldal S, Kjolby M, Richner M, Erdmann B, Nyengaard JR, Tessarollo L et al (2011) Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci 14:54-61
-
(2011)
Nat Neurosci
, vol.14
, pp. 54-61
-
-
Vaegter, C.B.1
Jansen, P.2
Fjorback, A.W.3
Glerup, S.4
Skeldal, S.5
Kjolby, M.6
Richner, M.7
Erdmann, B.8
Nyengaard, J.R.9
Tessarollo, L.10
-
12
-
-
0008747975
-
Uptake of lipoproteins for axonal growth of sympathetic neurons
-
Posse De Chaves EI, Vance DE, Campenot RB, Kiss RS, Vance JE (2000) Uptake of lipoproteins for axonal growth of sympathetic neurons. J Biol Chem 275:19883-19890
-
(2000)
J Biol Chem
, vol.275
, pp. 19883-19890
-
-
Posse De Chaves, E.I.1
Vance, D.E.2
Campenot, R.B.3
Kiss, R.S.4
Vance, J.E.5
-
13
-
-
79953134227
-
SorLA regulates the activity of lipoprotein lipase by intracellular trafficking
-
Klinger SC, Glerup S, Raarup MK, Mari MC, Nyegaard M, Koster G, Prabakaran T, Nilsson SK, Kjaergaard MM, Bakke O et al (2011) SorLA regulates the activity of lipoprotein lipase by intracellular trafficking. J Cell Sci 124:1095-1105
-
(2011)
J Cell Sci
, vol.124
, pp. 1095-1105
-
-
Klinger, S.C.1
Glerup, S.2
Raarup, M.K.3
Mari, M.C.4
Nyegaard, M.5
Koster, G.6
Prabakaran, T.7
Nilsson, S.K.8
Kjaergaard, M.M.9
Bakke, O.10
-
14
-
-
59049099831
-
A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins
-
Merianda TT, Lin AC, Lam JSY, Vuppalanchi D, Willis DE, Karin N, Holt CE, Twiss JL (2009) A functional equivalent of endoplasmic reticulum and Golgi in axons for secretion of locally synthesized proteins. Mol Cell Neurosci 40:128-142
-
(2009)
Mol Cell Neurosci
, vol.40
, pp. 128-142
-
-
Merianda, T.T.1
Lin, A.C.2
Lam, J.S.Y.3
Vuppalanchi, D.4
Willis, D.E.5
Karin, N.6
Holt, C.E.7
Twiss, J.L.8
-
15
-
-
33748313351
-
Retrograde transport from endosomes to the trans-Golgi network
-
Bonifacino JS, Rojas R (2006) Retrograde transport from endosomes to the trans-Golgi network. Nat Rev Mol Cell Biol 7:568-579
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 568-579
-
-
Bonifacino, J.S.1
Rojas, R.2
-
17
-
-
0033081042
-
Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR
-
Bibel M, Hoppe E, Barde YA (1999) Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR. EMBO J 18:616-622
-
(1999)
EMBO J
, vol.18
, pp. 616-622
-
-
Bibel, M.1
Hoppe, E.2
Barde, Y.A.3
-
18
-
-
0037762690
-
Neurotrophins and their receptors: A convergence point for many signalling pathways
-
Chao MV (2003) Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat Rev Neurosci 4:299-309
-
(2003)
Nat Rev Neurosci
, vol.4
, pp. 299-309
-
-
Chao, M.V.1
-
19
-
-
20044370999
-
ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin
-
Teng HK, Teng KK, Lee R, Wright S, Tevar S, Almeida RD, Kermani P, Torkin R, Chen Z-Y, Lee FS et al (2005) ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci 25:5455-5463
-
(2005)
J Neurosci
, vol.25
, pp. 5455-5463
-
-
Teng, H.K.1
Teng, K.K.2
Lee, R.3
Wright, S.4
Tevar, S.5
Almeida, R.D.6
Kermani, P.7
Torkin, R.8
Chen, Z.-Y.9
Lee, F.S.10
-
20
-
-
0035976524
-
Regulation of cell survival by secreted proneurotrophins
-
Lee R, Kermani P, Teng KK, Hempstead BL (2001) Regulation of cell survival by secreted proneurotrophins. Science 294:1945-1948
-
(2001)
Science
, vol.294
, pp. 1945-1948
-
-
Lee, R.1
Kermani, P.2
Teng, K.K.3
Hempstead, B.L.4
-
21
-
-
10744219632
-
Sortilin is essential for proNGF-induced neuronal cell death
-
Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE et al (2004) Sortilin is essential for proNGF-induced neuronal cell death. Nature 427:843-848
-
(2004)
Nature
, vol.427
, pp. 843-848
-
-
Nykjaer, A.1
Lee, R.2
Teng, K.K.3
Jansen, P.4
Madsen, P.5
Nielsen, M.S.6
Jacobsen, C.7
Kliemannel, M.8
Schwarz, E.9
Willnow, T.E.10
-
22
-
-
35548930820
-
Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury
-
Jansen P, Giehl K, Nyengaard JR, Teng K, Lioubinski O, Sjoegaard SS, Breiderhoff T, Gotthardt M, Lin F, Eilers A et al (2007) Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury. Nat Neurosci 10:1449-1457
-
(2007)
Nat Neurosci
, vol.10
, pp. 1449-1457
-
-
Jansen, P.1
Giehl, K.2
Nyengaard, J.R.3
Teng, K.4
Lioubinski, O.5
Sjoegaard, S.S.6
Breiderhoff, T.7
Gotthardt, M.8
Lin, F.9
Eilers, A.10
-
23
-
-
77956300096
-
Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not
-
Nikoletopoulou V, Lickert H, Frade JM, Rencurel C, Giallonardo P, Zhang L, Bibel M, Barde Y-A (2010) Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not. Nature 467:59-63
-
(2010)
Nature
, vol.467
, pp. 59-63
-
-
Nikoletopoulou, V.1
Lickert, H.2
Frade, J.M.3
Rencurel, C.4
Giallonardo, P.5
Zhang, L.6
Bibel, M.7
Barde, Y.-A.8
-
24
-
-
5644251587
-
Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity
-
Pang PT, Teng HK, Zaitsev E, Woo NT, Sakata K, Zhen S, Teng KK, Yung W-H, Hempstead BL, Lu B (2004) Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity. Science 306:487-491
-
(2004)
Science
, vol.306
, pp. 487-491
-
-
Pang, P.T.1
Teng, H.K.2
Zaitsev, E.3
Woo, N.T.4
Sakata, K.5
Zhen, S.6
Teng, K.K.7
Yung, W.-H.8
Hempstead, B.L.9
Lu, B.10
-
25
-
-
23044464168
-
Activation of p75NTR by proBDNF facilitates hippocampal long-term depression
-
Woo NH, Teng HK, Siao CJ, Chiaruttini C, Pang PT, Milner TA, Hempstead BL, Lu B (2005) Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Nat Neurosci 8:1069-1077
-
(2005)
Nat Neurosci
, vol.8
, pp. 1069-1077
-
-
Woo, N.H.1
Teng, H.K.2
Siao, C.J.3
Chiaruttini, C.4
Pang, P.T.5
Milner, T.A.6
Hempstead, B.L.7
Lu, B.8
-
26
-
-
34548336779
-
New insights into BDNF function in depression and anxiety
-
Martinowich K, Manji H, Lu B (2007) New insights into BDNF function in depression and anxiety. Nat Neurosci 10:1089-1093
-
(2007)
Nat Neurosci
, vol.10
, pp. 1089-1093
-
-
Martinowich, K.1
Manji, H.2
Lu, B.3
-
27
-
-
0027402152
-
Multiple promoters direct tissue-specific expression of the rat BDNF gene
-
Timmusk T, Palm K, Metsis M, Reintam T, Paalme V, Saarma M, Persson H (1993) Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron 10:475-489
-
(1993)
Neuron
, vol.10
, pp. 475-489
-
-
Timmusk, T.1
Palm, K.2
Metsis, M.3
Reintam, T.4
Paalme, V.5
Saarma, M.6
Persson, H.7
-
28
-
-
14644390283
-
Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo
-
Pattabiraman PP, Tropea D, Chiaruttini C, Tongiorgi E, Cattaneo A, Domenici L (2005) Neuronal activity regulates the developmental expression and subcellular localization of cortical BDNF mRNA isoforms in vivo. Mol Cell Neurosci 28:556-570
-
(2005)
Mol Cell Neurosci
, vol.28
, pp. 556-570
-
-
Pattabiraman, P.P.1
Tropea, D.2
Chiaruttini, C.3
Tongiorgi, E.4
Cattaneo, A.5
Domenici, L.6
-
29
-
-
0141894133
-
Neuronal polarity and trafficking
-
Horton AC, Ehlers MD (2003) Neuronal polarity and trafficking. Neuron 40:277-295
-
(2003)
Neuron
, vol.40
, pp. 277-295
-
-
Horton, A.C.1
Ehlers, M.D.2
-
30
-
-
0033559386
-
Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons
-
Mowla SJ, Pareek S, Farhadi HF, Petrecca K, Fawcett JP, Seidah NG, Morris SJ, Sossin WS, Murphy RA (1999) Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons. J Neurosci 19:2069-2080
-
(1999)
J Neurosci
, vol.19
, pp. 2069-2080
-
-
Mowla, S.J.1
Pareek, S.2
Farhadi, H.F.3
Petrecca, K.4
Fawcett, J.P.5
Seidah, N.G.6
Morris, S.J.7
Sossin, W.S.8
Murphy, R.A.9
-
31
-
-
12344328770
-
Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e
-
Lou H, Kim S-K, Zaitsev E, Snell CR, Lu B, Loh YP (2005) Sorting and activity-dependent secretion of BDNF require interaction of a specific motif with the sorting receptor carboxypeptidase e. Neuron 45:245-255
-
(2005)
Neuron
, vol.45
, pp. 245-255
-
-
Lou, H.1
Kim, S.-K.2
Zaitsev, E.3
Snell, C.R.4
Lu, B.5
Loh, Y.P.6
-
32
-
-
21544461501
-
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway
-
Chen Z-Y, Ieraci A, Teng H, Dall H, Meng C-X, Herrera DG, Nykjaer A, Hempstead BL, Lee FS (2005) Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway. J Neurosci 25:6156-6166
-
(2005)
J Neurosci
, vol.25
, pp. 6156-6166
-
-
Chen, Z.-Y.1
Ieraci, A.2
Teng, H.3
Dall, H.4
Meng, C.-X.5
Herrera, D.G.6
Nykjaer, A.7
Hempstead, B.L.8
Lee, F.S.9
-
33
-
-
77249091890
-
Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: Effects of gender and ethnicity
-
Verhagen M, van der Meij A, van Deurzen PAM, Janzing JGE, Arias-Vásquez A, Buitelaar JK, Franke B (2010) Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. Mol Psychiatry 15:260-271
-
(2010)
Mol Psychiatry
, vol.15
, pp. 260-271
-
-
Verhagen, M.1
Van Der Meij, A.2
Van Deurzen, P.A.M.3
Janzing, J.G.E.4
Arias-Vásquez, A.5
Buitelaar, J.K.6
Franke, B.7
-
34
-
-
77955431930
-
The BDNF Val66Met polymorphism and anxiety: Support for animal knock-in studies from a genetic association study in humans
-
Montag C, Basten U, Stelzel C, Fiebach CJ, Reuter M (2010) The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans. Psychiatry Res 179:86-90
-
(2010)
Psychiatry Res
, vol.179
, pp. 86-90
-
-
Montag, C.1
Basten, U.2
Stelzel, C.3
Fiebach, C.J.4
Reuter, M.5
-
35
-
-
78149267659
-
Variant brain-derived neurotrophic factor Val66Met endophenotypes: Implications for posttraumatic stress disorder
-
Frielingsdorf H, Bath KG, Soliman F, Difede J, Casey BJ, Lee FS (2010) Variant brain-derived neurotrophic factor Val66Met endophenotypes: implications for posttraumatic stress disorder. Ann N Y Acad Sci 1208:150-157
-
(2010)
Ann N Y Acad Sci
, vol.1208
, pp. 150-157
-
-
Frielingsdorf, H.1
Bath, K.G.2
Soliman, F.3
Difede, J.4
Casey, B.J.5
Lee, F.S.6
-
36
-
-
77954421126
-
The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus
-
Ninan I, Bath KG, Dagar K, Perez-Castro R, Plummer MR, Lee FS, Chao MV (2010) The BDNF Val66Met polymorphism impairs NMDA receptor-dependent synaptic plasticity in the hippocampus. J Neurosci 30:8866-8870
-
(2010)
J Neurosci
, vol.30
, pp. 8866-8870
-
-
Ninan, I.1
Bath, K.G.2
Dagar, K.3
Perez-Castro, R.4
Plummer, M.R.5
Lee, F.S.6
Chao, M.V.7
-
37
-
-
0030726894
-
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin
-
Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA (1997) Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum Mol Genet 6:2205-2212
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2205-2212
-
-
Engelender, S.1
Sharp, A.H.2
Colomer, V.3
Tokito, M.K.4
Lanahan, A.5
Worley, P.6
Holzbaur, E.L.7
Ross, C.A.8
-
38
-
-
0032563107
-
A human HAP1 homologue. Cloning, expression, and interaction with huntingtin
-
Li SH, Hosseini SH, Gutekunst CA, Hersch SM, Ferrante RJ, Li XJ (1998) A human HAP1 homologue. Cloning, expression, and interaction with huntingtin. J Biol Chem 273:19220-19227
-
(1998)
J Biol Chem
, vol.273
, pp. 19220-19227
-
-
Li, S.H.1
Hosseini, S.H.2
Gutekunst, C.A.3
Hersch, S.M.4
Ferrante, R.J.5
Li, X.J.6
-
39
-
-
33645642673
-
Interaction of Huntingtin-associated protein-1 with kinesin light chain: Implications in intracellular trafficking in neurons
-
McGuire JR, Rong J, Li S-H, Li X-J (2006) Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. J Biol Chem 281:3552-3559
-
(2006)
J Biol Chem
, vol.281
, pp. 3552-3559
-
-
McGuire, J.R.1
Rong, J.2
Li, S.-H.3
Li, X.-J.4
-
40
-
-
79955507013
-
Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation and processing
-
Yang M, Lim Y, Li X, Zhong J-H, Zhou X-F (2011) Precursor of brain-derived neurotrophic factor (proBDNF) forms a complex with huntingtin associated protein-1 (HAP1) and sortilin that modulates proBDNF trafficking, degradation and processing. J Biol Chem 286:16272-16284
-
(2011)
J Biol Chem
, vol.286
, pp. 16272-16284
-
-
Yang, M.1
Lim, Y.2
Li, X.3
Zhong, J.-H.4
Zhou, X.-F.5
-
41
-
-
80051940841
-
Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation
-
Evans SF, Irmady K, Ostrow K, Kim T, Nykjaer A, Saftig P, Blobel C, Hempstead BL (2011) Neuronal brain-derived neurotrophic factor is synthesized in excess, with levels regulated by sortilin-mediated trafficking and lysosomal degradation. J Biol Chem 286:29556-29567
-
(2011)
J Biol Chem
, vol.286
, pp. 29556-29567
-
-
Evans, S.F.1
Irmady, K.2
Ostrow, K.3
Kim, T.4
Nykjaer, A.5
Saftig, P.6
Blobel, C.7
Hempstead, B.L.8
-
42
-
-
79960455447
-
Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?
-
Skeldal S, Matusica D, Nykjaer A, Coulson EJ (2011) Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?: neuronal life, growth and death signalling are crucially regulated by intra-membrane proteolysis and trafficking of p75 (NTR). Bioessays 33:614-625
-
(2011)
Neuronal Life, Growth and Death Signalling Are Crucially Regulated by Intra-membrane Proteolysis and Trafficking of P75 (NTR). Bioessays
, vol.33
, pp. 614-625
-
-
Skeldal, S.1
Matusica, D.2
Nykjaer, A.3
Coulson, E.J.4
-
43
-
-
33747051514
-
Interaction of survival and death signaling in basal forebrain neurons: Roles of neurotrophins and proneurotrophins
-
Volosin M, Song W, Almeida RD, Kaplan DR, Hempstead BL, Friedman WJ (2006) Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. J Neurosci 26:7756-7766
-
(2006)
J Neurosci
, vol.26
, pp. 7756-7766
-
-
Volosin, M.1
Song, W.2
Almeida, R.D.3
Kaplan, D.R.4
Hempstead, B.L.5
Friedman, W.J.6
-
44
-
-
11144355567
-
Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury
-
Harrington AW, Leiner B, Blechschmitt C, Arevalo JC, Lee R, Mörl K, Meyer M, Hempstead BL, Yoon SO, Giehl KM (2004) Secreted proNGF is a pathophysiological death-inducing ligand after adult CNS injury. Proc Natl Acad Sci U S A 101:6226-6230
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 6226-6230
-
-
Harrington, A.W.1
Leiner, B.2
Blechschmitt, C.3
Arevalo, J.C.4
Lee, R.5
Mörl, K.6
Meyer, M.7
Hempstead, B.L.8
Yoon, S.O.9
Giehl, K.M.10
-
45
-
-
37549030132
-
p75NTR and sortilin increase after facial nerve injury
-
Provenzano MJ, Xu N, Ver Meer MR, Clark JJ, Hansen MR (2008) p75NTR and sortilin increase after facial nerve injury. Laryngoscope 118:87-93
-
(2008)
Laryngoscope
, vol.118
, pp. 87-93
-
-
Provenzano, M.J.1
Xu, N.2
Ver Meer, M.R.3
Clark, J.J.4
Hansen, M.R.5
-
46
-
-
36448986390
-
Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia
-
Wei Y, Wang N, Lu Q, Zhang N, Zheng D, Li J (2007) Enhanced protein expressions of sortilin and p75NTR in retina of rat following elevated intraocular pressure-induced retinal ischemia. Neurosci Lett 429:169-174
-
(2007)
Neurosci Lett
, vol.429
, pp. 169-174
-
-
Wei, Y.1
Wang, N.2
Lu, Q.3
Zhang, N.4
Zheng, D.5
Li, J.6
-
47
-
-
43049146531
-
Up-regulation of pro-nerve growth factor, neurotrophin receptor p75, and sortilin is associated with retrovirus-induced spongiform encephalomyelopathy
-
Stoica G, Lungu G, Kim H-T, Wong PKY (2008) Up-regulation of pro-nerve growth factor, neurotrophin receptor p75, and sortilin is associated with retrovirus-induced spongiform encephalomyelopathy. Brain Res 1208:204-216
-
(2008)
Brain Res
, vol.1208
, pp. 204-216
-
-
Stoica, G.1
Lungu, G.2
Kim, H.-T.3
Wong, P.K.Y.4
-
48
-
-
33750950147
-
The dynamic distribution of TrkB receptors before, during, and after synapse formation between cortical neurons
-
Gomes RA, Hampton C, El-Sabeawy F, Sabo SL, McAllister AK (2006) The dynamic distribution of TrkB receptors before, during, and after synapse formation between cortical neurons. J Neurosci 26:11487-11500
-
(2006)
J Neurosci
, vol.26
, pp. 11487-11500
-
-
Gomes, R.A.1
Hampton, C.2
El-Sabeawy, F.3
Sabo, S.L.4
McAllister, A.K.5
-
50
-
-
0028291238
-
Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents
-
Ernfors P, Lee KF, Kucera J, Jaenisch R (1994) Lack of neurotrophin-3 leads to deficiencies in the peripheral nervous system and loss of limb proprioceptive afferents. Cell 77:503-512
-
(1994)
Cell
, vol.77
, pp. 503-512
-
-
Ernfors, P.1
Lee, K.F.2
Kucera, J.3
Jaenisch, R.4
-
51
-
-
0027491104
-
Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death
-
Klein R, Smeyne RJ, Wurst W, Long LK, Auerbach BA, Joyner AL, Barbacid M (1993) Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death. Cell 75:113-122
-
(1993)
Cell
, vol.75
, pp. 113-122
-
-
Klein, R.1
Smeyne, R.J.2
Wurst, W.3
Long, L.K.4
Auerbach, B.A.5
Joyner, A.L.6
Barbacid, M.7
-
52
-
-
0029558477
-
Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons
-
Minichiello L, Piehl F, Vazquez E, Schimmang T, Hökfelt T, Represa J, Klein R (1995) Differential effects of combined trk receptor mutations on dorsal root ganglion and inner ear sensory neurons. Development 121:4067-4075
-
(1995)
Development
, vol.121
, pp. 4067-4075
-
-
Minichiello, L.1
Piehl, F.2
Vazquez, E.3
Schimmang, T.4
Hökfelt, T.5
Represa, J.6
Klein, R.7
-
53
-
-
0028223015
-
Clinical and neuropathological criteria for frontotemporal dementia
-
Englund B et al (1994) Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry 57:416-418
-
(1994)
J Neurol Neurosurg Psychiatry
, vol.57
, pp. 416-418
-
-
Englund, B.1
-
54
-
-
4444248435
-
Clinicopathological correlates in frontotemporal dementia
-
Hodges JR, Davies RR, Xuereb JH, Casey B, Broe M, Bak TH, Kril JJ, Halliday GM (2004) Clinicopathological correlates in frontotemporal dementia. Ann Neurol 56:399-406
-
(2004)
Ann Neurol
, vol.56
, pp. 399-406
-
-
Hodges, J.R.1
Davies, R.R.2
Xuereb, J.H.3
Casey, B.4
Broe, M.5
Bak, T.H.6
Kril, J.J.7
Halliday, G.M.8
-
55
-
-
4344642855
-
Frontotemporal lobar degeneration and ubiquitin immunohistochemistry
-
Josephs KA, Holton JL, Rossor MN, Godbolt AK, Ozawa T, Strand K, Khan N, Al-Sarraj S, Revesz T (2004) Frontotemporal lobar degeneration and ubiquitin immunohistochemistry. Neuropathol Appl Neurobiol 30:369-373
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, pp. 369-373
-
-
Josephs, K.A.1
Holton, J.L.2
Rossor, M.N.3
Godbolt, A.K.4
Ozawa, T.5
Strand, K.6
Khan, N.7
Al-Sarraj, S.8
Revesz, T.9
-
56
-
-
84860389481
-
Progranulin and TDP-43: Mechanistic links and future directions
-
Kumar-Singh S (2011) Progranulin and TDP-43: Mechanistic links and future directions. J Mol Neurosci 45:561-573
-
(2011)
J Mol Neurosci
, vol.45
, pp. 561-573
-
-
Kumar-Singh, S.1
-
57
-
-
79953180492
-
Characterizing the RNA targets and position-dependent splicing regulation by TDP-43
-
Tollervey JR, Curk T, Rogelj B, Briese M, Cereda M, Kayikci M, Konig J, Hortobagyi T, Nishimura AL, Zupunski V et al (2011) Characterizing the RNA targets and position-dependent splicing regulation by TDP-43. Nat Neurosci 14:452-458
-
(2011)
Nat Neurosci
, vol.14
, pp. 452-458
-
-
Tollervey, J.R.1
Curk, T.2
Rogelj, B.3
Briese, M.4
Cereda, M.5
Kayikci, M.6
Konig, J.7
Hortobagyi, T.8
Nishimura, A.L.9
Zupunski, V.10
-
58
-
-
38349128462
-
A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder
-
Baum AE, Akula N, Cabanero M, Cardona I, Corona W, Klemens B, Schulze TG, Cichon S, Rietschel M, Nothen MM et al (2008) A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder. Mol Psychiatry 13:197-207
-
(2008)
Mol Psychiatry
, vol.13
, pp. 197-207
-
-
Baum, A.E.1
Akula, N.2
Cabanero, M.3
Cardona, I.4
Corona, W.5
Klemens, B.6
Schulze, T.G.7
Cichon, S.8
Rietschel, M.9
Nothen, M.M.10
-
59
-
-
79953185674
-
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43
-
Polymenidou M, Lagier-Tourenne C, Hutt KR, Huelga SC, Moran J, Liang TY, Ling SC, Sun E,Wancewicz E, Mazur C et al (2011) Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nat Neurosci 14:459-468
-
(2011)
Nat Neurosci
, vol.14
, pp. 459-468
-
-
Polymenidou, M.1
Lagier-Tourenne, C.2
Hutt, K.R.3
Huelga, S.C.4
Moran, J.5
Liang, T.Y.6
Ling, S.C.7
Sun, E.8
Wancewicz, E.9
Mazur, C.10
-
60
-
-
0033635553
-
Quantitative neurohistological features of frontotemporal degeneration
-
Arnold SE, Han LY, Clark CM, Grossman M, Trojanowski JQ (2000) Quantitative neurohistological features of frontotemporal degeneration. Neurobiol Aging 21:913-919
-
(2000)
Neurobiol Aging
, vol.21
, pp. 913-919
-
-
Arnold, S.E.1
Han, L.Y.2
Clark, C.M.3
Grossman, M.4
Trojanowski, J.Q.5
-
61
-
-
77956850818
-
TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia
-
Mackenzie IR, Rademakers R, Neumann M (2010) TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia. Lancet Neurol 9:995-1007
-
(2010)
Lancet Neurol
, vol.9
, pp. 995-1007
-
-
Mackenzie, I.R.1
Rademakers, R.2
Neumann, M.3
-
62
-
-
33746919083
-
Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17
-
Baker M, Mackenzie IR, Pickering-Brown SM, Gass J, Rademakers R, Lindholm C, Snowden J, Adamson J, Sadovnick AD, Rollinson S et al (2006) Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 442:916-919
-
(2006)
Nature
, vol.442
, pp. 916-919
-
-
Baker, M.1
Mackenzie, I.R.2
Pickering-Brown, S.M.3
Gass, J.4
Rademakers, R.5
Lindholm, C.6
Snowden, J.7
Adamson, J.8
Sadovnick, A.D.9
Rollinson, S.10
-
63
-
-
33746910649
-
Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21
-
Cruts M, Gijselinck I, van der Zee J, Engelborghs S, Wils H, Pirici D, Rademakers R, Vandenberghe R, Dermaut B, Martin J-J et al (2006) Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21. Nature 442:920-924
-
(2006)
Nature
, vol.442
, pp. 920-924
-
-
Cruts, M.1
Gijselinck, I.2
Van Der Zee, J.3
Engelborghs, S.4
Wils, H.5
Pirici, D.6
Rademakers, R.7
Vandenberghe, R.8
Dermaut, B.9
Martin, J.-J.10
-
64
-
-
80855130704
-
Potential mechanisms of progranulin-deficient FTLD
-
Ward ME, Miller BL (2011) Potential mechanisms of progranulin-deficient FTLD. J Mol Neurosci 45:574-582
-
(2011)
J Mol Neurosci
, vol.45
, pp. 574-582
-
-
Ward, M.E.1
Miller, B.L.2
-
65
-
-
33750590113
-
The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene
-
Mackenzie IRA, Baker M, Pickering-Brown S, Hsiung G-YR, Lindholm C, Dwosh E, Gass J, Cannon A, Rademakers R, Hutton M et al (2006) The neuropathology of frontotemporal lobar degeneration caused by mutations in the progranulin gene. Brain 129:3081-3090
-
(2006)
Brain
, vol.129
, pp. 3081-3090
-
-
Mackenzie, I.R.A.1
Baker, M.2
Pickering-Brown, S.3
Hsiung, G.-Y.R.4
Lindholm, C.5
Dwosh, E.6
Gass, J.7
Cannon, A.8
Rademakers, R.9
Hutton, M.10
-
66
-
-
78449286213
-
Sortilinmediated endocytosis determines levels of the frontotemporal dementia protein, progranulin
-
Hu F, Padukkavidana T, Vaegter CB, Brady OA, Zheng Y, Mackenzie IR, Feldman HH, Nykjaer A, Strittmatter SM (2010) Sortilinmediated endocytosis determines levels of the frontotemporal dementia protein, progranulin. Neuron 68:654-667
-
(2010)
Neuron
, vol.68
, pp. 654-667
-
-
Hu, F.1
Padukkavidana, T.2
Vaegter, C.B.3
Brady, O.A.4
Zheng, Y.5
Mackenzie, I.R.6
Feldman, H.H.7
Nykjaer, A.8
Strittmatter, S.M.9
-
67
-
-
79958831842
-
C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking
-
Zheng Y, Brady OA, Meng PS, Mao Y, Hu F (2011) C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking. PLoS One 6:e21023
-
(2011)
PLoS One
, vol.6
-
-
Zheng, Y.1
Brady, O.A.2
Meng, P.S.3
Mao, Y.4
Hu, F.5
-
68
-
-
77954578417
-
Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging
-
Ahmed Z, Sheng H, Xu YF, Lin WL, Innes AE, Gass J, Yu X, Wuertzer CA, Hou H, Chiba S et al (2010) Accelerated lipofuscinosis and ubiquitination in granulin knockout mice suggest a role for progranulin in successful aging. Am J Pathol 177:311-324
-
(2010)
Am J Pathol
, vol.177
, pp. 311-324
-
-
Ahmed, Z.1
Sheng, H.2
Xu, Y.F.3
Lin, W.L.4
Innes, A.E.5
Gass, J.6
Yu, X.7
Wuertzer, C.A.8
Hou, H.9
Chiba, S.10
-
69
-
-
78649796276
-
Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma
-
Carrasquillo MM, Nicholson AM, Finch N, Gibbs JR, Baker M, Rutherford NJ, Hunter TA, DeJesus-Hernandez M, Bisceglio GD, Mackenzie IR et al (2010) Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma. Am J Hum Genet 87:890-897
-
(2010)
Am J Hum Genet
, vol.87
, pp. 890-897
-
-
Carrasquillo, M.M.1
Nicholson, A.M.2
Finch, N.3
Gibbs, J.R.4
Baker, M.5
Rutherford, N.J.6
Hunter, T.A.7
DeJesus-Hernandez, M.8
Bisceglio, G.D.9
Mackenzie, I.R.10
-
70
-
-
33847662852
-
Soluble protein oligomers in neurodegeneration: Lessons from the Alzheimer's amyloid beta-peptide
-
Haass C, Selkoe DJ (2007) Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide. Nat Rev Mol Cell Biol 8:101-112
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 101-112
-
-
Haass, C.1
Selkoe, D.J.2
-
71
-
-
33749042749
-
Sorting through the cell biology of Alzheimer's disease: Intracellular pathways to pathogenesis
-
Small SA, Gandy S (2006) Sorting through the cell biology of Alzheimer's disease: intracellular pathways to pathogenesis. Neuron 52:15-31
-
(2006)
Neuron
, vol.52
, pp. 15-31
-
-
Small, S.A.1
Gandy, S.2
-
72
-
-
4043141580
-
Loss of apolipoprotein e receptor LR11 in Alzheimer disease
-
Scherzer CR, Offe K, Gearing M, Rees HD, Fang G, Heilman CJ, Schaller C, Bujo H, Levey AI, Lah JJ (2004) Loss of apolipoprotein E receptor LR11 in Alzheimer disease. Arch Neurol 61:1200-1205
-
(2004)
Arch Neurol
, vol.61
, pp. 1200-1205
-
-
Scherzer, C.R.1
Offe, K.2
Gearing, M.3
Rees, H.D.4
Fang, G.5
Heilman, C.J.6
Schaller, C.7
Bujo, H.8
Levey, A.I.9
Lah, J.J.10
-
73
-
-
26444607532
-
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein
-
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X et al (2005) Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein. Proc Natl Acad Sci U S A 102:13461-13466
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13461-13466
-
-
Andersen, O.M.1
Reiche, J.2
Schmidt, V.3
Gotthardt, M.4
Spoelgen, R.5
Behlke, J.6
Von Arnim, C.A.7
Breiderhoff, T.8
Jansen, P.9
Wu, X.10
-
74
-
-
33748536734
-
LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease
-
Dodson SE, Gearing M, Lippa CF, Montine TJ, Levey AI, Lah JJ (2006) LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease. J Neuropathol Exp Neurol 65:866-872
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 866-872
-
-
Dodson, S.E.1
Gearing, M.2
Lippa, C.F.3
Montine, T.J.4
Levey, A.I.5
Lah, J.J.6
-
75
-
-
78651297619
-
Meta-analysis of the association between variants in SORL1 and Alzheimer disease
-
Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R et al (2011) Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Arch Neurol 68:99-106
-
(2011)
Arch Neurol
, vol.68
, pp. 99-106
-
-
Reitz, C.1
Cheng, R.2
Rogaeva, E.3
Lee, J.H.4
Tokuhiro, S.5
Zou, F.6
Bettens, K.7
Sleegers, K.8
Tan, E.K.9
Kimura, R.10
-
76
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R,Hasegawa Het al (2007) The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet 39:168-177
-
(2007)
Nat Genet
, vol.39
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
Gu, Y.4
Kawarai, T.5
Zou, F.6
Katayama, T.7
Baldwin, C.T.8
Cheng, R.9
Hasegawa, H.10
-
77
-
-
34247177933
-
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort
-
Lee JH, Cheng R, Schupf N, Manly J, Lantigua R, Stern Y, Rogaeva E, Wakutani Y, Farrer L, St George-Hyslop P et al (2007) The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Arch Neurol 64:501-506
-
(2007)
Arch Neurol
, vol.64
, pp. 501-506
-
-
Lee, J.H.1
Cheng, R.2
Schupf, N.3
Manly, J.4
Lantigua, R.5
Stern, Y.6
Rogaeva, E.7
Wakutani, Y.8
Farrer, L.9
St George-Hyslop, P.10
-
78
-
-
80053906759
-
Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers
-
Alexopoulos P, Guo L-H, Kratzer M, Westerteicher C, Kurz A, Perneczky R (2011) Impact of SORL1 single nucleotide polymorphisms on Alzheimer's disease cerebrospinal fluid markers. Dement Geriatr Cogn Disord 32:164-170
-
(2011)
Dement Geriatr Cogn Disord
, vol.32
, pp. 164-170
-
-
Alexopoulos, P.1
Guo, L.-H.2
Kratzer, M.3
Westerteicher, C.4
Kurz, A.5
Perneczky, R.6
-
79
-
-
63649164073
-
Trafficking, a key player in regulated intramembrane proteolysis
-
Sannerud R, Annaert W (2009) Trafficking, a key player in regulated intramembrane proteolysis. Semin Cell Dev Biol 20:183-190
-
(2009)
Semin Cell Dev Biol
, vol.20
, pp. 183-190
-
-
Sannerud, R.1
Annaert, W.2
-
80
-
-
33644516276
-
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11
-
Andersen OM, Schmidt V, Spoelgen R, Gliemann J, Behlke J, Galatis D, McKinstry WJ, Parker MW, Masters CL, Hyman BT et al (2006) Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11. Biochemistry 45:2618-2628
-
(2006)
Biochemistry
, vol.45
, pp. 2618-2628
-
-
Andersen, O.M.1
Schmidt, V.2
Spoelgen, R.3
Gliemann, J.4
Behlke, J.5
Galatis, D.6
McKinstry, W.J.7
Parker, M.W.8
Masters, C.L.9
Hyman, B.T.10
-
81
-
-
32544435097
-
The Lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments
-
Offe K, Dodson SE, Shoemaker JT, Fritz JJ, Gearing M, Levey AI, Lah JJ (2006) The Lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments. J Neurosci 26:1596-1603
-
(2006)
J Neurosci
, vol.26
, pp. 1596-1603
-
-
Offe, K.1
Dodson, S.E.2
Shoemaker, J.T.3
Fritz, J.J.4
Gearing, M.5
Levey, A.I.6
Lah, J.J.7
-
82
-
-
36349025159
-
SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1
-
Schmidt V, Sporbert A, Rohe M, Reimer T, Rehm A, Andersen OM, Willnow TE (2007) SorLA/LR11 regulates processing of amyloid precursor protein via interaction with adaptors GGA and PACS-1. J Biol Chem 282:32956-32964
-
(2007)
J Biol Chem
, vol.282
, pp. 32956-32964
-
-
Schmidt, V.1
Sporbert, A.2
Rohe, M.3
Reimer, T.4
Rehm, A.5
Andersen, O.M.6
Willnow, T.E.7
-
83
-
-
58149373433
-
Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: Evidence for a proximal role in Alzheimer's disease
-
Dodson SE, Andersen OM, Karmali V, Fritz JJ, Cheng D, Peng J, Levey AI, Willnow TE, Lah JJ (2008) Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease. J Neurosci 28:12877-12886
-
(2008)
J Neurosci
, vol.28
, pp. 12877-12886
-
-
Dodson, S.E.1
Andersen, O.M.2
Karmali, V.3
Fritz, J.J.4
Cheng, D.5
Peng, J.6
Levey, A.I.7
Willnow, T.E.8
Lah, J.J.9
-
84
-
-
47249144294
-
Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis
-
Rohe M, Carlo A-S, Breyhan H, Sporbert A, Militz D, Schmidt V, Wozny C, Harmeier A, Erdmann B, Bales KR et al (2008) Sortilin-related receptor with A-type repeats (SORLA) affects the amyloid precursor protein-dependent stimulation of ERK signaling and adult neurogenesis. J Biol Chem 283:14826-14834
-
(2008)
J Biol Chem
, vol.283
, pp. 14826-14834
-
-
Rohe, M.1
Carlo, A.-S.2
Breyhan, H.3
Sporbert, A.4
Militz, D.5
Schmidt, V.6
Wozny, C.7
Harmeier, A.8
Erdmann, B.9
Bales, K.R.10
-
85
-
-
33749348509
-
A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking
-
Scott GK, Fei H, Thomas L, Medigeshi GR, Thomas G (2006) A PACS-1, GGA3 and CK2 complex regulates CI-MPR trafficking. EMBO J 25:4423-4435
-
(2006)
EMBO J
, vol.25
, pp. 4423-4435
-
-
Scott, G.K.1
Fei, H.2
Thomas, L.3
Medigeshi, G.R.4
Thomas, G.5
-
86
-
-
0037196416
-
The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding
-
Jacobsen L, Madsen P, Nielsen MS, Geraerts WPM, Gliemann J, Smit AB, Petersen CM (2002) The sorLA cytoplasmic domain interacts with GGA1 and -2 and defines minimum requirements for GGA binding. FEBS Lett 511:155-158
-
(2002)
FEBS Lett
, vol.511
, pp. 155-158
-
-
Jacobsen, L.1
Madsen, P.2
Nielsen, M.S.3
Geraerts, W.P.M.4
Gliemann, J.5
Smit, A.B.6
Petersen, C.M.7
-
87
-
-
27744576858
-
Model-guided microarray implicates the retromer complex in Alzheimer's disease
-
Small SA, Kent K, Pierce A, Leung C, Kang MS, Okada H, Honig L, Vonsattel J-P, Kim T-W (2005) Model-guided microarray implicates the retromer complex in Alzheimer's disease. Ann Neurol 58:909-919
-
(2005)
Ann Neurol
, vol.58
, pp. 909-919
-
-
Small, S.A.1
Kent, K.2
Pierce, A.3
Leung, C.4
Kang, M.S.5
Okada, H.6
Honig, L.7
Vonsattel, J.-P.8
Kim, T.-W.9
-
88
-
-
44449165118
-
Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation
-
Muhammad A, Flores I, Zhang H, Yu R, Staniszewski A, Planel E, Herman M, Ho L, Kreber R, Honig LS et al (2008) Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation. Proc Natl Acad Sci U S A 105:7327-7332
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 7327-7332
-
-
Muhammad, A.1
Flores, I.2
Zhang, H.3
Yu, R.4
Staniszewski, A.5
Planel, E.6
Herman, M.7
Ho, L.8
Kreber, R.9
Honig, L.S.10
-
89
-
-
84863011338
-
Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing
-
Fjorback AW, Seaman M, Gustafsen C, Mehmedbasic A, Gokool S, Wu C, Militz D, Schmidt V, Madsen P, Nyengaard JR et al (2012) Retromer binds the FANSHY sorting motif in SorLA to regulate amyloid precursor protein sorting and processing. J Neurosci 32:1467-1480
-
(2012)
J Neurosci
, vol.32
, pp. 1467-1480
-
-
Fjorback, A.W.1
Seaman, M.2
Gustafsen, C.3
Mehmedbasic, A.4
Gokool, S.5
Wu, C.6
Militz, D.7
Schmidt, V.8
Madsen, P.9
Nyengaard, J.R.10
-
90
-
-
0035573660
-
LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro
-
Taira K, Bujo H, Hirayama S, Yamazaki H, Kanaki T, Takahashi K, Ishii I, Miida T, Schneider WJ, Saito Y (2001) LR11, a mosaic LDL receptor family member, mediates the uptake of ApoE-rich lipoproteins in vitro. Arterioscler Thromb Vasc Biol 21:1501-1506
-
(2001)
Arterioscler Thromb Vasc Biol
, vol.21
, pp. 1501-1506
-
-
Taira, K.1
Bujo, H.2
Hirayama, S.3
Yamazaki, H.4
Kanaki, T.5
Takahashi, K.6
Ishii, I.7
Miida, T.8
Schneider, W.J.9
Saito, Y.10
-
91
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
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