-
1
-
-
68549126922
-
The cytoskeleton and cancer
-
Hall, A. The cytoskeleton and cancer. Cancer Metastasis Rev. 2009, 28, 5-14.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 5-14
-
-
Hall, A.1
-
2
-
-
0032939619
-
Rho GTPases are over-expressed in human tumors
-
Fritz, G.; Just, I.; Kaina, B. Rho GTPases are over-expressed in human tumors. Int. J. Cancer 1999, 81, 682-687.
-
(1999)
Int. J. Cancer
, vol.81
, pp. 682-687
-
-
Fritz, G.1
Just, I.2
Kaina, B.3
-
3
-
-
0037048326
-
Rho GTPases in human breast tumours: Expression and mutation analyses and correlation with clinical parameters
-
Fritz, G.; Brachetti, C.; Bahlmann, F.; Schmidt, M.; Kaina, B. Rho GTPases in human breast tumours: Expression and mutation analyses and correlation with clinical parameters. Br. J. Cancer 2002, 87, 635-644.
-
(2002)
Br. J. Cancer
, vol.87
, pp. 635-644
-
-
Fritz, G.1
Brachetti, C.2
Bahlmann, F.3
Schmidt, M.4
Kaina, B.5
-
4
-
-
78650927755
-
Pleiotropic functions of Rho GTPase signaling: A Trojan horse or Achilles' heel for breast cancer treatment
-
McHenry, P.R.; Vargo-Gogola, T. Pleiotropic functions of Rho GTPase signaling: A Trojan horse or Achilles' heel for breast cancer treatment? Curr. Drug Targets 2010, 11, 1043-1058.
-
(2010)
Curr. Drug Targets
, vol.11
, pp. 1043-1058
-
-
McHenry, P.R.1
Vargo-Gogola, T.2
-
5
-
-
67649522162
-
Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis
-
Holland, A.J.; Cleveland, D.W. Boveri revisited: Chromosomal instability, aneuploidy and tumorigenesis. Nat. Rev. 2009, 10, 478-487.
-
(2009)
Nat. Rev
, vol.10
, pp. 478-487
-
-
Holland, A.J.1
Cleveland, D.W.2
-
6
-
-
0037455574
-
RhoA is required for cortical retraction and rigidity during mitotic cell rounding
-
Maddox, A.S.; Burridge, K. RhoA is required for cortical retraction and rigidity during mitotic cell rounding. J. Cell Biol. 2003, 160, 255-265.
-
(2003)
J. Cell Biol
, vol.160
, pp. 255-265
-
-
Maddox, A.S.1
Burridge, K.2
-
7
-
-
79955382980
-
RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts
-
Melendez, J.; Stengel, K.; Zhou, X.; Chauhan, B.K.; Debidda, M.; Andreassen, P.; Lang, R.A.; Zheng, Y. RhoA GTPase is dispensable for actomyosin regulation but is essential for mitosis in primary mouse embryonic fibroblasts. J. Biol. Chem. 2011, 286, 15132-15137.
-
(2011)
J. Biol. Chem
, vol.286
, pp. 15132-15137
-
-
Melendez, J.1
Stengel, K.2
Zhou, X.3
Chauhan, B.K.4
Debidda, M.5
Andreassen, P.6
Lang, R.A.7
Zheng, Y.8
-
8
-
-
77950627707
-
Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression
-
Woodcock, S.A.; Rushton, H.J.; Castaneda-Saucedo, E.; Myant, K.; White, G.R.; Blyth, K.; Sansom, O.J.; Malliri, A. Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression. Curr. Biol. 2010, 20, 669-675.
-
(2010)
Curr. Biol
, vol.20
, pp. 669-675
-
-
Woodcock, S.A.1
Rushton, H.J.2
Castaneda-Saucedo, E.3
Myant, K.4
White, G.R.5
Blyth, K.6
Sansom, O.J.7
Malliri, A.8
-
9
-
-
1942455757
-
Cdc42 and mDia3 regulate microtubule attachment to kinetochores
-
Yasuda, S.; Oceguera-Yanez, F.; Kato, T.; Okamoto, M.; Yonemura, S.; Terada, Y.; Ishizaki, T.; Narumiya, S. Cdc42 and mDia3 regulate microtubule attachment to kinetochores. Nature 2004, 428, 767-771.
-
(2004)
Nature
, vol.428
, pp. 767-771
-
-
Yasuda, S.1
Oceguera-Yanez, F.2
Kato, T.3
Okamoto, M.4
Yonemura, S.5
Terada, Y.6
Ishizaki, T.7
Narumiya, S.8
-
10
-
-
78149469280
-
RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication
-
Kanai, M.; Crowe, M.S.; Zheng, Y.; Vande Woude, G.F.; Fukasawa, K. RhoA and RhoC are both required for the ROCK II-dependent promotion of centrosome duplication. Oncogene 2010, 29, 6040-6050.
-
(2010)
Oncogene
, vol.29
, pp. 6040-6050
-
-
Kanai, M.1
Crowe, M.S.2
Zheng, Y.3
vande Woude, G.F.4
Fukasawa, K.5
-
11
-
-
0032559362
-
Rho GTPases and the actin cytoskeleton
-
Hall, A. Rho GTPases and the actin cytoskeleton. Science 1998, 279, 509-514.
-
(1998)
Science
, vol.279
, pp. 509-514
-
-
Hall, A.1
-
12
-
-
79953853847
-
Loss of Rho GDIalpha and resistance to tamoxifen via effects on estrogen receptor alpha
-
Barone, I.; Brusco, L.; Gu, G.; Selever, J.; Beyer, A.; Covington, K.R.; Tsimelzon, A.; Wang, T.; Hilsenbeck, S.G.; Chamness, G.C.; Ando, S.; Fuqua, S.A. Loss of Rho GDIalpha and resistance to tamoxifen via effects on estrogen receptor alpha. J. Natl. Cancer Inst. 2011, 103, 538-552.
-
(2011)
J. Natl. Cancer Inst
, vol.103
, pp. 538-552
-
-
Barone, I.1
Brusco, L.2
Gu, G.3
Selever, J.4
Beyer, A.5
Covington, K.R.6
Tsimelzon, A.7
Wang, T.8
Hilsenbeck, S.G.9
Chamness, G.C.10
Ando, S.11
Fuqua, S.A.12
-
13
-
-
78650305929
-
The role of fibroblast Tiam1 in tumor cell invasion and metastasis
-
Xu, K.; Rajagopal, S.; Klebba, I.; Dong, S.; Ji, Y.; Liu, J.; Kuperwasser, C.; Garlick, J.A.; Naber, S.P.; Buchsbaum, R.J. The role of fibroblast Tiam1 in tumor cell invasion and metastasis. Oncogene 2010, 29, 6533-6542.
-
(2010)
Oncogene
, vol.29
, pp. 6533-6542
-
-
Xu, K.1
Rajagopal, S.2
Klebba, I.3
Dong, S.4
Ji, Y.5
Liu, J.6
Kuperwasser, C.7
Garlick, J.A.8
Naber, S.P.9
Buchsbaum, R.J.10
-
14
-
-
56649124726
-
Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice
-
Strumane, K.; Rygiel, T.; van der Valk, M.; Collard, J.G. Tiam1-deficiency impairs mammary tumor formation in MMTV-c-neu but not in MMTV-c-myc mice. J. Cancer Res. Clin. Oncol. 2009, 135, 69-80.
-
(2009)
J. Cancer Res. Clin. Oncol
, vol.135
, pp. 69-80
-
-
Strumane, K.1
Rygiel, T.2
van der Valk, M.3
Collard, J.G.4
-
15
-
-
0029594555
-
P190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking
-
Burbelo, P.D.; Miyamoto, S.; Utani, A.; Brill, S.; Yamada, K.M.; Hall, A.; Yamada, Y. p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking. J. Biol. Chem. 1995, 270, 30919-30926.
-
(1995)
J. Biol. Chem
, vol.270
, pp. 30919-30926
-
-
Burbelo, P.D.1
Miyamoto, S.2
Utani, A.3
Brill, S.4
Yamada, K.M.5
Hall, A.6
Yamada, Y.7
-
16
-
-
54149096498
-
Coordination of Rho and Rac GTPase function via p190B RhoGAP
-
Bustos, R.I.; Forget, M.A.; Settleman, J.E.; Hansen, S.H. Coordination of Rho and Rac GTPase function via p190B RhoGAP. Curr. Biol. 2008, 18, 1606-1611.
-
(2008)
Curr. Biol
, vol.18
, pp. 1606-1611
-
-
Bustos, R.I.1
Forget, M.A.2
Settleman, J.E.3
Hansen, S.H.4
-
17
-
-
77449112267
-
Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression
-
doi:10.1186/bcr2352
-
Heckman-Stoddard, B.M.; Vargo-Gogola, T.; McHenry, P.R.; Jiang, V.; Herrick, M.P.; Hilsenbeck, S.G.; Settleman, J.; Rosen, J.M. Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression. Breast Cancer Res. 2009, 11, doi:10.1186/bcr2352.
-
(2009)
Breast Cancer Res
, vol.11
-
-
Heckman-Stoddard, B.M.1
Vargo-Gogola, T.2
McHenry, P.R.3
Jiang, V.4
Herrick, M.P.5
Hilsenbeck, S.G.6
Settleman, J.7
Rosen, J.M.8
-
18
-
-
78650949091
-
P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis
-
doi:10.1186/bcr2643
-
McHenry, P.R.; Sears, J.C.; Herrick, M.P.; Chang, P.; Heckman-Stoddard, B.M.; Rybarczyk, M.; Chodosh, L.A.; Gunther, E.J.; Hilsenbeck, S.G.; Rosen, J.M.; Vargo-Gogola, T. P190B RhoGAP has pro-tumorigenic functions during MMTV-Neu mammary tumorigenesis and metastasis. Breast Cancer Res. 2010, 12, doi:10.1186/bcr2643.
-
(2010)
Breast Cancer Res
, vol.12
-
-
McHenry, P.R.1
Sears, J.C.2
Herrick, M.P.3
Chang, P.4
Heckman-Stoddard, B.M.5
Rybarczyk, M.6
Chodosh, L.A.7
Gunther, E.J.8
Hilsenbeck, S.G.9
Rosen, J.M.10
Vargo-Gogola, T.11
-
19
-
-
0242425847
-
P190rhogap is cell cycle regulated and affects cytokinesis
-
Su, L.; Agati, J.M.; Parsons, S.J. p190RhoGAP is cell cycle regulated and affects cytokinesis. J. Cell Biol. 2003, 163, 571-582.
-
(2003)
J. Cell Biol
, vol.163
, pp. 571-582
-
-
Su, L.1
Agati, J.M.2
Parsons, S.J.3
-
20
-
-
64049115859
-
P190rhogap negatively regulates Rho activity at the cleavage furrow of mitotic cells
-
Su, L.; Pertz, O.; Mikawa, M.; Hahn, K.; Parsons, S.J. p190RhoGAP negatively regulates Rho activity at the cleavage furrow of mitotic cells. Exp. Cell Res. 2009, 315, 1347-1359.
-
(2009)
Exp. Cell Res
, vol.315
, pp. 1347-1359
-
-
Su, L.1
Pertz, O.2
Mikawa, M.3
Hahn, K.4
Parsons, S.J.5
-
21
-
-
47749118760
-
Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis
-
Mikawa, M.; Su, L.; Parsons, S.J. Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis. Cell Cycle (Georgetown, Tex) 2008, 7, 2003-2012.
-
(2008)
Cell Cycle (Georgetown, Tex)
, vol.7
, pp. 2003-2012
-
-
Mikawa, M.1
Su, L.2
Parsons, S.J.3
-
22
-
-
77956261156
-
Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesis
-
Manchinelly, S.A.; Miller, J.A.; Su, L.; Miyake, T.; Palmer, L.; Mikawa, M.; Parsons, S.J. Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesis. J. Biol. Chem. 1998, 285, 26923-26932.
-
(1998)
J. Biol. Chem
, vol.285
, pp. 26923-26932
-
-
Manchinelly, S.A.1
Miller, J.A.2
Su, L.3
Miyake, T.4
Palmer, L.5
Mikawa, M.6
Parsons, S.J.7
-
23
-
-
0037453716
-
Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis
-
Sordella, R.; Jiang, W.; Chen, G.C.; Curto, M.; Settleman, J. Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell 2003, 113, 147-158.
-
(2003)
Cell
, vol.113
, pp. 147-158
-
-
Sordella, R.1
Jiang, W.2
Chen, G.C.3
Curto, M.4
Settleman, J.5
-
24
-
-
2942589265
-
SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway
-
Kontaridis, M.I.; Eminaga, S.; Fornaro, M.; Zito, C.I.; Sordella, R.; Settleman, J.; Bennett, A.M. SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Mol. Cell. Biol. 2004, 24, 5340-5352.
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 5340-5352
-
-
Kontaridis, M.I.1
Eminaga, S.2
Fornaro, M.3
Zito, C.I.4
Sordella, R.5
Settleman, J.6
Bennett, A.M.7
-
25
-
-
49449085504
-
Quantitative atlas of mitotic phosphorylation
-
Dephoure, N.; Zhou, C.; Villen, J.; Beausoleil, S.A.; Bakalarski, C.E.; Elledge, S.J.; Gygi, S.P. A quantitative atlas of mitotic phosphorylation. Proc. Natl. Acad. Sci. USA 2008, 105, 10762-10767.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 10762-10767
-
-
Dephoure, N.1
Zhou, C.2
Villen, J.3
Beausoleil, S.A.4
Bakalarski, C.E.5
Elledge, S.J.6
Gygi, S.P.A.7
-
26
-
-
0031724591
-
Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation
-
Roof, R.W.; Haskell, M.D.; Dukes, B.D.; Sherman, N.; Kinter, M.; Parsons, S.J. Phosphotyrosine (p-Tyr)-dependent and -independent mechanisms of p190 RhoGAP-p120 RasGAP interaction: Tyr 1105 of p190, a substrate for c-Src, is the sole p-Tyr mediator of complex formation. Mol. Cell. Biol. 1998, 18, 7052-7063.
-
(1998)
Mol. Cell. Biol
, vol.18
, pp. 7052-7063
-
-
Roof, R.W.1
Haskell, M.D.2
Dukes, B.D.3
Sherman, N.4
Kinter, M.5
Parsons, S.J.6
-
27
-
-
0029153801
-
C-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation
-
Chang, J.H.; Gill, S.; Settleman, J.; Parsons, S.J. C-Src regulates the simultaneous rearrangement of actin cytoskeleton, p190RhoGAP, and p120RasGAP following epidermal growth factor stimulation. J. Cell Biol. 1995, 130, 355-368.
-
(1995)
J. Cell Biol
, vol.130
, pp. 355-368
-
-
Chang, J.H.1
Gill, S.2
Settleman, J.3
Parsons, S.J.4
-
29
-
-
78650664775
-
Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells
-
Fenech, M.; Kirsch-Volders, M.; Natarajan, A.T.; Surralles, J.; Crott, J.W.; Parry, J.; Norppa, H.; Eastmond, D.A.; Tucker, J.D.; Thomas, P. Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells. Mutagenesis 2011, 26, 125-132.
-
(2011)
Mutagenesis
, vol.26
, pp. 125-132
-
-
Fenech, M.1
Kirsch-Volders, M.2
Natarajan, A.T.3
Surralles, J.4
Crott, J.W.5
Parry, J.6
Norppa, H.7
Eastmond, D.A.8
Tucker, J.D.9
Thomas, P.10
-
30
-
-
0035972237
-
Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells
-
Cimini, D.; Howell, B.; Maddox, P.; Khodjakov, A.; Degrassi, F.; Salmon, E.D. Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells. J. Cell Biol. 2001, 153, 517-527.
-
(2001)
J. Cell Biol
, vol.153
, pp. 517-527
-
-
Cimini, D.1
Howell, B.2
Maddox, P.3
Khodjakov, A.4
Degrassi, F.5
Salmon, E.D.6
-
31
-
-
33750612373
-
Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors
-
Cimini, D.; Wan, X.; Hirel, C.B.; Salmon, E.D. Aurora kinase promotes turnover of kinetochore microtubules to reduce chromosome segregation errors. Curr. Biol. 2006, 16, 1711-1718.
-
(2006)
Curr. Biol
, vol.16
, pp. 1711-1718
-
-
Cimini, D.1
Wan, X.2
Hirel, C.B.3
Salmon, E.D.4
-
32
-
-
8444237458
-
G protein control of microtubule assembly
-
Zheng, Y. G protein control of microtubule assembly. Annu. Rev. Cell Dev. Biol. 2004, 20, 867-894.
-
(2004)
Annu. Rev. Cell Dev. Biol
, vol.20
, pp. 867-894
-
-
Zheng, Y.1
-
33
-
-
33749548216
-
Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development
-
Matheson, S.F.; Hu, K.Q.; Brouns, M.R.; Sordella, R.; VanderHeide, J.D.; Settleman, J. Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development. Dev. Neurosci. 2006, 28, 538-550.
-
(2006)
Dev. Neurosci
, vol.28
, pp. 538-550
-
-
Matheson, S.F.1
Hu, K.Q.2
Brouns, M.R.3
Sordella, R.4
Vanderheide, J.D.5
Settleman, J.6
-
34
-
-
0038517913
-
P190-B RhoGAP regulates mammary ductal morphogenesis
-
Chakravarty, G.; Hadsell, D.; Buitrago, W.; Settleman, J.; Rosen, J.M. p190-B RhoGAP regulates mammary ductal morphogenesis. Mol. Endocrinol. (Baltimore, MD) 2003, 17, 1054-1065.
-
(2003)
Mol. Endocrinol. (Baltimore, MD)
, vol.17
, pp. 1054-1065
-
-
Chakravarty, G.1
Hadsell, D.2
Buitrago, W.3
Settleman, J.4
Rosen, J.M.5
-
35
-
-
80755153153
-
P190A RhoGAP is required for mammary gland development
-
Heckman-Stoddard, B.M.; Vargo-Gogola, T.; Herrick, M.P.; Visbal, A.P.; Lewis, M.T.; Settleman, J.; Rosen, J.M. P190A RhoGAP is required for mammary gland development. Dev. Biol. 2011, 360, 1-10.
-
(2011)
Dev. Biol
, vol.360
, pp. 1-10
-
-
Heckman-Stoddard, B.M.1
Vargo-Gogola, T.2
Herrick, M.P.3
Visbal, A.P.4
Lewis, M.T.5
Settleman, J.6
Rosen, J.M.7
-
36
-
-
77955486630
-
Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase
-
Vazquez-Novelle, M.D.; Petronczki, M. Relocation of the chromosomal passenger complex prevents mitotic checkpoint engagement at anaphase. Curr. Biol. 2010, 20, 1402-1407.
-
(2010)
Curr. Biol
, vol.20
, pp. 1402-1407
-
-
Vazquez-Novelle, M.D.1
Petronczki, M.2
-
37
-
-
84857690106
-
Kinetochore flexibility: Creating a dynamic chromosome-spindle interface
-
O'Connell, C.B.; Khodjakov, A.; McEwen, B.F. Kinetochore flexibility: Creating a dynamic chromosome-spindle interface. Curr. Opin. Cell Biol. 2012, 24, 40-47.
-
(2012)
Curr. Opin. Cell Biol
, vol.24
, pp. 40-47
-
-
O'Connell, C.B.1
Khodjakov, A.2
McEwen, B.F.3
-
38
-
-
35948943082
-
Aneuploidy: Instigator and inhibitor of tumorigenesis
-
Weaver, B.A.; Cleveland, D.W. Aneuploidy: Instigator and inhibitor of tumorigenesis. Cancer Res. 2007, 67, 10103-10105.
-
(2007)
Cancer Res
, vol.67
, pp. 10103-10105
-
-
Weaver, B.A.1
Cleveland, D.W.2
-
39
-
-
0347915641
-
Increases in estrogen receptor-alpha concentration in breast cancer cells promote serine 118/104/106-independent AF-1 transactivation and growth in the absence of estrogen
-
Fowler, A.M.; Solodin, N.; Preisler-Mashek, M.T.; Zhang, P.; Lee, A.V.; Alarid, E.T. Increases in estrogen receptor-alpha concentration in breast cancer cells promote serine 118/104/106-independent AF-1 transactivation and growth in the absence of estrogen. FASEB J. 2004, 18, 81-93.
-
(2004)
FASEB J
, vol.18
, pp. 81-93
-
-
Fowler, A.M.1
Solodin, N.2
Preisler-Mashek, M.T.3
Zhang, P.4
Lee, A.V.5
Alarid, E.T.6
|