메뉴 건너뛰기




Volumn 92, Issue 1, 2012, Pages 103-111

Erratum: Compartment-specific gene regulation of the car inducer efavirenz in vivo (Clinical Pharmacology and Therapeutics (2012) 92 (103-111) DOI: 10.1038/clpt.2012.34);Compartment-specific gene regulation of the CAR inducer efavirenz in vivo

Author keywords

[No Author keywords available]

Indexed keywords

4BETA HYDROXYCHOLESTEROL; BILIRUBIN; CHOLESTEROL DERIVATIVE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 2B6; EFAVIRENZ; EZETIMIBE; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84862591111     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.213     Document Type: Erratum
Times cited : (32)

References (50)
  • 1
    • 0032169485 scopus 로고    scopus 로고
    • The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
    • Lehmann, J.M., McKee, D.D., Watson, M.A., Willson, T.M., Moore, J.T. & Kliewer, S.A. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J. Clin. Invest. 102, 1016-1023 (1998).
    • (1998) J. Clin. Invest. , vol.102 , pp. 1016-1023
    • Lehmann, J.M.1    McKee, D.D.2    Watson, M.A.3    Willson, T.M.4    Moore, J.T.5    Kliewer, S.A.6
  • 2
  • 3
    • 0037016761 scopus 로고    scopus 로고
    • Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor
    • Gerbal-Chaloin, S., Daujat, M., Pascussi, J.M., Pichard-Garcia, L., Vilarem, M.J. &Maurel, P. Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor. J. Biol. Chem. 277, 209-217 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 209-217
    • Gerbal-Chaloin, S.1    Daujat, M.2    Pascussi, J.M.3    Pichard-Garcia, L.4    Vilarem, M.J.5    Maurel, P.6
  • 4
    • 1342344703 scopus 로고    scopus 로고
    • Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression
    • Gardner-Stephen, D. et al. Human PXR variants and their differential effects on the regulation of human UDP-glucuronosyltransferase gene expression. Drug Metab. Dispos. 32, 340-347 (2004).
    • (2004) Drug Metab. Dispos. , vol.32 , pp. 340-347
    • Gardner-Stephen, D.1
  • 5
    • 1042287037 scopus 로고    scopus 로고
    • The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics
    • Sugatani, J. et al. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics. Biochem. Pharmacol. 67, 989-1000 (2004).
    • (2004) Biochem. Pharmacol. , vol.67 , pp. 989-1000
    • Sugatani, J.1
  • 7
    • 38749090899 scopus 로고    scopus 로고
    • Regulation of sulfotransferase enzymes by prototypical microsomal enzyme inducers in mice
    • Alnouti, Y. & Klaassen, C.D. Regulation of sulfotransferase enzymes by prototypical microsomal enzyme inducers in mice. J. Pharmacol. Exp. Ther. 324, 612-621 (2008).
    • (2008) J. Pharmacol. Exp. Ther. , vol.324 , pp. 612-621
    • Alnouti, Y.1    Klaassen, C.D.2
  • 8
    • 56449083452 scopus 로고    scopus 로고
    • Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer
    • Meyer Zu Schwabedissen, H.E., Tirona, R.G., Yip, C.S., Ho, R.H. & Kim, R.B. Interplay between the nuclear receptor pregnane X receptor and the uptake transporter organic anion transporter polypeptide 1A2 selectively enhances estrogen effects in breast cancer. Cancer. Res. 68, 9338-9347 (2008).
    • (2008) Cancer. Res. , vol.68 , pp. 9338-9347
    • Meyer Zu Schwabedissen, H.E.1    Tirona, R.G.2    Yip, C.S.3    Ho, R.H.4    Kim, R.B.5
  • 9
    • 0035805536 scopus 로고    scopus 로고
    • Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin
    • Geick, A., Eichelbaum, M. & Burk, O. Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. J. Biol. Chem. 276, 14581-14587 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 14581-14587
    • Geick, A.1    Eichelbaum, M.2    Burk, O.3
  • 10
    • 0346099111 scopus 로고    scopus 로고
    • Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes
    • Wang, H. & LeCluyse, E.L. Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes. Clin. Pharmacokinet. 42, 1331-1357 (2003).
    • (2003) Clin. Pharmacokinet. , vol.42 , pp. 1331-1357
    • Wang, H.1    LeCluyse, E.L.2
  • 11
    • 0034691064 scopus 로고    scopus 로고
    • St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor
    • Moore, L.B. et al. St. John's wort induces hepatic drug metabolism through activation of the pregnane X receptor. Proc. Natl. Acad. Sci. USA 97, 7500-7502 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 7500-7502
    • Moore, L.B.1
  • 12
    • 72949089249 scopus 로고    scopus 로고
    • Herb-drug interactions with St John's wort (Hypericum perforatum): An update on clinical observations
    • Borrelli, F. & Izzo, A.A. Herb-drug interactions with St John's wort (Hypericum perforatum): an update on clinical observations. AAPS J. 11, 710-727 (2009).
    • (2009) AAPS J. , vol.11 , pp. 710-727
    • Borrelli, F.1    Izzo, A.A.2
  • 13
    • 26844549175 scopus 로고    scopus 로고
    • A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression
    • Burk, O., Arnold, K.A., Geick, A., Tegude, H. & Eichelbaum, M. A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression. Biol. Chem. 386, 503-513 (2005).
    • (2005) Biol. Chem. , vol.386 , pp. 503-513
    • Burk, O.1    Arnold, K.A.2    Geick, A.3    Tegude, H.4    Eichelbaum, M.5
  • 14
    • 0037016761 scopus 로고    scopus 로고
    • Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor
    • Gerbal-Chaloin, S., Daujat, M., Pascussi, J.M., Pichard-Garcia, L., Vilarem, M.J. &Maurel, P. Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor. J. Biol. Chem. 277, 209-217 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 209-217
    • Gerbal-Chaloin, S.1    Daujat, M.2    Pascussi, J.M.3    Pichard-Garcia, L.4    Vilarem, M.J.5    Maurel, P.6
  • 15
    • 0033525886 scopus 로고    scopus 로고
    • The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
    • Sueyoshi, T., Kawamoto, T., Zelko, I., Honkakoski, P. & Negishi, M. The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. J. Biol. Chem. 274, 6043-6046 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 6043-6046
    • Sueyoshi, T.1    Kawamoto, T.2    Zelko, I.3    Honkakoski, P.4    Negishi, M.5
  • 16
    • 0035029401 scopus 로고    scopus 로고
    • The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR
    • Sugatani, J. et al. The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR. Hepatology 33, 1232-1238 (2001).
    • (2001) Hepatology , vol.33 , pp. 1232-1238
    • Sugatani, J.1
  • 17
    • 0035918186 scopus 로고    scopus 로고
    • Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics
    • Smirlis, D., Muangmoonchai, R., Edwards, M., Phillips, I.R. & Shephard, E.A. Orphan receptor promiscuity in the induction of cytochromes p450 by xenobiotics. J. Biol. Chem. 276, 12822-12826 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 12822-12826
    • Smirlis, D.1    Muangmoonchai, R.2    Edwards, M.3    Phillips, I.R.4    Shephard, E.A.5
  • 18
    • 0028210426 scopus 로고
    • A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements
    • Baes, M., Gulick, T., Choi, H.S., Martinoli, M.G., Simha, D. & Moore, D.D. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements. Mol. Cell. Biol. 14, 1544-1552 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1544-1552
    • Baes, M.1    Gulick, T.2    Choi, H.S.3    Martinoli, M.G.4    Simha, D.5    Moore, D.D.6
  • 19
    • 0037931737 scopus 로고    scopus 로고
    • Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
    • Maglich, J.M. et al. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J. Biol. Chem. 278, 17277-17283 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 17277-17283
    • Maglich, J.M.1
  • 20
    • 22344439421 scopus 로고    scopus 로고
    • Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor
    • Kobayashi, K. et al. Identification of HMG-CoA reductase inhibitors as activators for human, mouse and rat constitutive androstane receptor. Drug Metab. Dispos. 33, 924-929 (2005).
    • (2005) Drug Metab. Dispos. , vol.33 , pp. 924-929
    • Kobayashi, K.1
  • 21
    • 33845881481 scopus 로고    scopus 로고
    • Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers
    • Faucette, S.R. et al. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers. J. Pharmacol. Exp. Ther. 320, 72-80 (2007).
    • (2007) J. Pharmacol. Exp. Ther. , vol.320 , pp. 72-80
    • Faucette, S.R.1
  • 22
    • 77958512342 scopus 로고    scopus 로고
    • Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients
    • Ngaimisi, E. et al. Long-term efavirenz autoinduction and its effect on plasma exposure in HIV patients. Clin. Pharmacol. Ther. 88, 676-684 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 676-684
    • Ngaimisi, E.1
  • 23
    • 21544472342 scopus 로고    scopus 로고
    • Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: Results of AIDS Clinical Trials Group 5108 Study
    • AIDS Clinical Trials Group A5108 Team
    • Gerber, J.G. et al.; AIDS Clinical Trials Group A5108 Team. Effect of efavirenz on the pharmacokinetics of simvastatin, atorvastatin, and pravastatin: results of AIDS Clinical Trials Group 5108 Study. J. Acquir. Immune Defic. Syndr. 39, 307-312 (2005).
    • (2005) J. Acquir. Immune Defic. Syndr. , vol.39 , pp. 307-312
    • Gerber, J.G.1
  • 24
    • 58149129621 scopus 로고    scopus 로고
    • 4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin
    • Diczfalusy, U., Kanebratt, K.P., Bredberg, E., Andersson, T.B., Böttiger, Y. &Bertilsson, L. 4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin. Br. J. Clin. Pharmacol. 67, 38-43 (2009).
    • (2009) Br. J. Clin. Pharmacol. , vol.67 , pp. 38-43
    • Diczfalusy, U.1    Kanebratt, K.P.2    Bredberg, E.3    Andersson, T.B.4    Böttiger, Y.5    Bertilsson, L.6
  • 25
    • 84857235431 scopus 로고    scopus 로고
    • Impact of efavirenz on intestinal metabolism and transport: Insights from an interaction study with ezetimibe in healthy volunteers
    • Oswald, S. et al. Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers. Clin. Pharmacol.Ther. 91, 506-513 (2012).
    • (2012) Clin. Pharmacol.Ther. , vol.91 , pp. 506-513
    • Oswald, S.1
  • 27
    • 37549069338 scopus 로고    scopus 로고
    • Transcription factor and drug-metabolizing enzyme gene expression in lymphocytes from healthy human subjects
    • Siest, G. et al. Transcription factor and drug-metabolizing enzyme gene expression in lymphocytes from healthy human subjects. Drug Metab. Dispos. 36, 182-189 (2008).
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 182-189
    • Siest, G.1
  • 28
    • 77954315743 scopus 로고    scopus 로고
    • Lack of P-glycoprotein induction by rifampicin and phenobarbital in human lymphocytes
    • Manceau, S. et al. Lack of P-glycoprotein induction by rifampicin and phenobarbital in human lymphocytes. Int. J. Pharm. 395, 98-103 (2010).
    • (2010) Int. J. Pharm. , vol.395 , pp. 98-103
    • Manceau, S.1
  • 30
    • 0042627777 scopus 로고    scopus 로고
    • The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro
    • Chandler, B. et al. The effects of protease inhibitors and nonnucleoside reverse transcriptase inhibitors on p-glycoprotein expression in peripheral blood mononuclear cells in vitro. J. Acquir. Immune Defic. Syndr. 33, 551-556 (2003).
    • (2003) J. Acquir. Immune Defic. Syndr. , vol.33 , pp. 551-556
    • Chandler, B.1
  • 31
    • 73949149076 scopus 로고    scopus 로고
    • Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes
    • Janneh, O. et al. Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes. J. Antimicrob. Chemother. 64, 1002-1007 (2009).
    • (2009) J. Antimicrob. Chemother. , vol.64 , pp. 1002-1007
    • Janneh, O.1
  • 32
    • 77957338981 scopus 로고    scopus 로고
    • No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment
    • Burhenne, J. et al. No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment. Antimicrob. Agents Chemother. 54, 4185-4191 (2010).
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 4185-4191
    • Burhenne, J.1
  • 33
    • 80051685348 scopus 로고    scopus 로고
    • Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenzcontaining regimens
    • German Competence Network for HIV/AIDS Coordinators
    • Wyen, C. et al.; German Competence Network for HIV/AIDS Coordinators. Cytochrome P450 2B6 (CYP2B6) and constitutive androstane receptor (CAR) polymorphisms are associated with early discontinuation of efavirenzcontaining regimens. J. Antimicrob. Chemother. 66, 2092-2098 (2011).
    • (2011) J. Antimicrob. Chemother. , vol.66 , pp. 2092-2098
    • Wyen, C.1
  • 34
    • 23744464363 scopus 로고    scopus 로고
    • Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver
    • Albermann, N. et al. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver. Biochem. Pharmacol. 70, 949-958 (2005).
    • (2005) Biochem. Pharmacol. , vol.70 , pp. 949-958
    • Albermann, N.1
  • 36
    • 0036335573 scopus 로고    scopus 로고
    • Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans
    • Mouly, S. et al. Hepatic but not intestinal CYP3A4 displays dose-dependent induction by efavirenz in humans. Clin. Pharmacol. Ther. 72, 1-9 (2002).
    • (2002) Clin. Pharmacol. Ther. , vol.72 , pp. 1-9
    • Mouly, S.1
  • 37
    • 0036367792 scopus 로고    scopus 로고
    • Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response
    • Wei, P., Zhang, J., Dowhan, D.H., Han, Y. & Moore, D.D. Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response. Pharmacogenomics J. 2, 117-126 (2002).
    • (2002) Pharmacogenomics J. , vol.2 , pp. 117-126
    • Wei, P.1    Zhang, J.2    Dowhan, D.H.3    Han, Y.4    Moore, D.D.5
  • 38
    • 77956237647 scopus 로고    scopus 로고
    • Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier
    • Wang, X., Sykes, D.B. & Miller, D.S. Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. Mol. Pharmacol. 78, 376-383 (2010).
    • (2010) Mol. Pharmacol. , vol.78 , pp. 376-383
    • Wang, X.1    Sykes, D.B.2    Miller, D.S.3
  • 40
    • 0035997339 scopus 로고    scopus 로고
    • Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture
    • Störmer, E., von Moltke, L.L., Perloff, M.D. & Greenblatt, D.J. Differential modulation of P-glycoprotein expression and activity by non-nucleoside HIV-1 reverse transcriptase inhibitors in cell culture. Pharm. Res. 19, 1038-1045 (2002).
    • (2002) Pharm. Res. , vol.19 , pp. 1038-1045
    • Störmer, E.1    Von Moltke, L.L.2    Perloff, M.D.3    Greenblatt, D.J.4
  • 42
    • 10744221611 scopus 로고    scopus 로고
    • Identification of novel alternative splice variants of human constitutive androstane receptor and characterization of their expression in the liver
    • Jinno, H. et al. Identification of novel alternative splice variants of human constitutive androstane receptor and characterization of their expression in the liver. Mol. Pharmacol. 65, 496-502 (2004).
    • (2004) Mol. Pharmacol. , vol.65 , pp. 496-502
    • Jinno, H.1
  • 43
    • 73949102632 scopus 로고    scopus 로고
    • A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3
    • Chen, T. et al. A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3. J. Pharmacol. Exp. Ther. 332, 106-115 (2010).
    • (2010) J. Pharmacol. Exp. Ther. , vol.332 , pp. 106-115
    • Chen, T.1
  • 44
    • 0035696398 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors
    • Smith, P.F., DiCenzo, R. & Morse, G.D. Clinical pharmacokinetics of non-nucleoside reverse transcriptase inhibitors. Clin. Pharmacokinet. 40, 893-905 (2001).
    • (2001) Clin. Pharmacokinet. , vol.40 , pp. 893-905
    • Smith, P.F.1    DiCenzo, R.2    Morse, G.D.3
  • 45
    • 6344266966 scopus 로고    scopus 로고
    • Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences
    • Lamba, J.K. et al. Expression of constitutive androstane receptor splice variants in human tissues and their functional consequences. J. Pharmacol. Exp. Ther. 311, 811-821 (2004).
    • (2004) J. Pharmacol. Exp. Ther. , vol.311 , pp. 811-821
    • Lamba, J.K.1
  • 46
    • 4344562884 scopus 로고    scopus 로고
    • Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor
    • Arnold, K.A., Eichelbaum, M. & Burk, O. Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor. Nucl. Recept. 2, 1 (2004).
    • (2004) Nucl. Recept. , vol.2 , pp. 1
    • Arnold, K.A.1    Eichelbaum, M.2    Burk, O.3
  • 47
    • 4544383423 scopus 로고    scopus 로고
    • Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans
    • Giessmann, T. et al. Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans. Clin. Pharmacol. Ther. 76, 192-200 (2004).
    • (2004) Clin. Pharmacol. Ther. , vol.76 , pp. 192-200
    • Giessmann, T.1
  • 48
    • 0025748762 scopus 로고
    • The measurement of bilirubin fractions in serum
    • Doumas, B.T. & Wu, T.W. The measurement of bilirubin fractions in serum. Crit. Rev. Clin. Lab. Sci. 28, 415-445 (1991).
    • (1991) Crit. Rev. Clin. Lab. Sci. , vol.28 , pp. 415-445
    • Doumas, B.T.1    Wu, T.W.2
  • 49
    • 71849114209 scopus 로고    scopus 로고
    • 4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - Effects of itraconazole in man
    • Lütjohann, D. et al. 4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man. Int. J. Clin. Pharmacol. Ther. 47, 709-715 (2009).
    • (2009) Int. J. Clin. Pharmacol. Ther. , vol.47 , pp. 709-715
    • Lütjohann, D.1
  • 50
    • 44949231424 scopus 로고    scopus 로고
    • Analyzing real-time PCR data by the comparative C(T) method
    • Schmittgen, T.D. & Livak, K.J. Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3, 1101-1108 (2008).
    • (2008) Nat. Protoc. , vol.3 , pp. 1101-1108
    • Schmittgen, T.D.1    Livak, K.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.