Lack of P-glycoprotein induction by rifampicin and phenobarbital in human lymphocytes

International Journal of Pharmaceutics

Volumn 395, Issue 1-2, 2010, Pages 98-103

  Manceau, S ^a,b   Giraud, C ^a,b   Decleves X ^c   Batteux, F ^a   Chouzenoux, S ^a   Tang, R ^c   Dauchy, S ^c   Scherrmann, J M ^c   Weill, B ^a   Morini, J P ^b   Perrot, J Y ^b   Treluyer J M ^a,b  

^a UNIVERSITÉ PARIS DESCARTES   (France)

^b ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^c INSERM   (France)

Author keywords

CAR; Lymphocyte; P glycoprotein; Phenobarbital; PXR; Rifampicin

Indexed keywords

CELL NUCLEUS RECEPTOR; CONSTITUTIVE ANDROSTANE RECEPTOR; GLYCOPROTEIN P; MULTIDRUG RESISTANCE PROTEIN 1; PHENOBARBITAL; PREGNANE X RECEPTOR; RIFAMPICIN; ABCB1 PROTEIN, HUMAN; CELL RECEPTOR; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN; STEROID RECEPTOR;

ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; EX VIVO STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTESTINE CELL; LIVER CELL; LYMPHOBLASTOID CELL LINE; LYMPHOCYTE; MEMBRANE TRANSPORT; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; DRUG EFFECTS; DRUG INTERACTION; GENETIC TRANSFECTION; GENETICS; HL 60 CELL LINE; METABOLISM; TIME; UPREGULATION;

DRUG INTERACTIONS; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; LYMPHOCYTES; P-GLYCOPROTEIN; P-GLYCOPROTEINS; PHENOBARBITAL; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; RIFAMPIN; RNA, MESSENGER; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 77954315743     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.05.016     Document Type: Article

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