Mercury-induced hepatotoxicity in zebrafish: In vivo mechanistic insights from transcriptome analysis, phenotype anchoring and targeted gene expression validation

BMC Genomics

Volumn 11, Issue 1, 2010, Pages

  Ung, Choong Y ^a   Lam, Siew H ^a   Hlaing, Mya M ^a   Winata, Cecilia L ^a   Korzh, Svetlana ^a   Mathavan, Sinnakaruppan ^b   Gong, Zhiyuan ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CELL NUCLEUS RECEPTOR; DNA; FATTY ACID; GLYCOGEN; MERCURY; MITOCHONDRIAL PROTEIN; PROTEASOME; TRANSCRIPTOME; WNT PROTEIN; ARSENIC;

ADIPOGENESIS; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL CYCLE; CELL MOTILITY; CONTROLLED STUDY; DISEASE MODEL; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DNA DAMAGE; ELECTRON TRANSPORT; ENDOCRINE DISEASE; FATTY ACID OXIDATION; FATTY ACID SYNTHESIS; GENE EXPRESSION PROFILING; GLUCONEOGENESIS; HUMAN; HUMAN CELL; IN VIVO STUDY; LIPID VESICLE; LIVER PARENCHYMA; LIVER TOXICITY; METABOLIC DISORDER; MICROARRAY ANALYSIS; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; RNA ANALYSIS; SIGNAL TRANSDUCTION; TOXICOGENETICS; VALIDATION PROCESS; ZEBRA FISH; ANIMAL; CELL ADHESION; CELL LINE; CYTOLOGY; DNA MICROARRAY; DRUG EFFECT; GENETICS; LIVER; LIVER CELL; METABOLISM;

ANIMALIA; DANIO RERIO;

ANIMALS; APOPTOSIS; ARSENIC; CELL ADHESION; CELL LINE; GENE EXPRESSION PROFILING; HEPATOCYTES; HUMANS; LIVER; MERCURY; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ZEBRAFISH;

EID: 77950384564     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-11-212     Document Type: Article

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