Modulation of lead biohazards using a combination of epicatechin and lycopene in rats

Human and Experimental Toxicology

Volumn 30, Issue 10, 2011, Pages 1674-1681

  Komousani, Taha A ^a   Moselhy, Said S ^a  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

epicatechin; lead toxicity; lycopene

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; EPICATECHIN; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LEAD; LOW DENSITY LIPOPROTEIN CHOLESTEROL; LYCOPENE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSAFETY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; ERYTHROCYTE; LEAD POISONING; LIPID PEROXIDATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALKALINE PHOSPHATASE; ANIMALS; ANTIOXIDANTS; CAROTENOIDS; CATECHIN; DRUG SYNERGISM; ENVIRONMENTAL POLLUTANTS; GLUTATHIONE; LEAD; LIPID PEROXIDATION; LIPIDS; MALE; ORGANOMETALLIC COMPOUNDS; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TRANSFERASES;

RATTUS;

EID: 80054850055     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327110396536     Document Type: Article

References (36)

1. Bauer JD Clinical Laboratory Methods. St. Louis, MO: The C.V. Mosby Co ; 1982 :
2. Hassanin LAM The effect of lead pollution on the susceptibility of rats to anticoagulants rodenticides. Faculty of Science, Cairo University, Giza, Egypt: M.Sc. Thesis. Zoology Department ; 1994 :
3. Latner AL. Clinical Biochemistry. Tramper C, ed. Philadelphia, PA: Sunders ; 1975: 180-199.
4. Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med. 1963 ; 61: 882-888
5. Bolognani Fantin AM, Franchini A, Trevisan P, Pederzoli A. Histopathological and cytochemical changes induced in the liver of goldenfish Carassius carassius var. auratus by short-term exposure to lead. Acta Histochem. 1992 ; 92: 228-235
6. Bradford M. Rapid and sensitive method for quantification of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 ; 72: 248-254
7. Cuzzocrea S, Reiter RJ. Pharmacological action of melatonin in shock, inflammation and ischemia/reprefusion injury. Eur J Pharmacol. 2001 ; 426: 1-10 (Pubitemid 32781781)
8. El-Missiry MA. Prophylactic effect of melatonin on lead induce inhibition of heme biosynthesis and deterioration of antioxidant system in male rats. J Biochem Mol Toxicol. 2000 ; 14: 57-62
9. Damek-Poprawa M, Sawicka-Kapusta K. Histopathological changes in the liver, kidneys, and testes of bank voles environmentally exposed to heavy metal emissions from the steelworks and zinc smelter in Poland. Environ Res. 2004 ; 96: 72-78 (Pubitemid 38916764)
10. El-Sokkary GH, Kamel ES, Reiter RJ. Prophylactic effect of melatonin in reducing lead-induced neurotoxicity in the rat. Cell Mol Biol Lett. 2003 ; 8: 461-470 (Pubitemid 36834664)
11. Esterbauer H, Cheeseman KH. Determination of aldehydic lipid peroxidation products: malondialdehyde and 4- hydroxyalkenals. Meth Enzymol. 1990 ; 186: 407-421 (Pubitemid 20279982)
12. Flora SJ, Pande M, Mehta A. Beneficial effect of combined administration of some naturally occurring antioxidants (vitamins) and thiol chelators in the treatment of chronic lead intoxication. Chem Biol Interact. 2003 ; 145: 267-280 (Pubitemid 36549111)
13. Stohs SJ, Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med. 1995 ; 18: 321-336
14. Tao-Tao L, Ning-Sheng L, Yan L, Fan Y, Yi L, Zi-Qing M, Li-Sheng Z. Effects of long-term tea polyphenols consumption on hepatic microsomal drug-metabolizing enzymes and liver function in Wistar rats. World J Gastroenterol. 2003 ; 9: 2742-2744
15. Susa N, Ueno S, Furukawa Y, Ueda J, Sugiyama M. Potent protective effect of melatonin on chromium(VI)-induced DNA single-strand breaks, cytotoxicity, and lipid peroxidation in primary cultures of rat hepatocytes. Toxicol Appl Pharmacol. 1997 ; 144: 377-384 (Pubitemid 27268360)
16. Buettner GR. The pecking order of free radicals and antioxidants: lipid peroxidation, a-tocopherol, and ascorbate. Arch Biochem Biophys. 1993 ; 300: 535-543 (Pubitemid 23232908)
17. Burton GW, Ingold KU. Vitamin E: application of the principles of physical organic chemistry to the exploration of its structure and function. Acc Chem Res. 1986 ; 19: 194-201
18. Moselhy SS, Al Meslamani MA. Chemopreventive effect of lycopene alone or with melatonin against the genesis of oxidative stress and mammary tumors induced by 7, 12 dimethyl(a)benzanthracene in Sprague Dawley female rats. Mol Cell Biochem. 2008 ; 319: 175-180
19. Gurer H, Ercal N. Can antioxidants be beneficial in the treatment of lead poisoning?. Free Radic Biol Med. 2000 ; 29: 927-945
20. Ribarov SR, Benov LC. Relationship between the hemolytic action of heavy metals and lipid peroxidation. Biochim Biophys Acta. 1981 ; 640: 721-726 (Pubitemid 11134807)
21. Hiraku Y, Kawanishi S. Mechanism of oxidative DNA damage induced by delta-aminolevulinic acid in the presence of copper ion. Cancer Res. 1996 ; 56: 1786-1793 (Pubitemid 26118214)
22. Sugawara E, Nakamura K, Miyake T, et al. Lipid peroxidation and concentration of glutathione in erythrocytes from workers exposed to lead. Br J Ind Med. 1991 ; 48: 239-242
23. Esterbauer H, Cheeseman KH. Determination of aldehydic lipid peroxidation products: malondialdehyde and 4-hydroxyalkenals. Meth Enzymol. 1990 ; 186: 407-421 (Pubitemid 20279982)
24. Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J Biol Chem. 1972 ; 247: 3170-3175
25. Beutler E, Duron O, Kelly BM. Improved method for the determination of blood glutathione. J Lab Clin Med. 1963 ; 61: 882-888
26. Chiba M, Shinohara A, Matsushita K, et al. Indices of lead-exposure in blood and urine of lead-exposed workers and concentrations of major and trace elements and activities of SOD, GSHPx and catalase in their blood. Tohoku J Exp Med. 1996 ; 178: 49-62 (Pubitemid 126542981)
27. Han SG, Kim Y, Kashon ML, et al. Correlates of oxidative stress and free-radical activity in serum from asymptomatic shipyard welders. Am J Respir Crit Care Med. 2005 ; 172: 1541-1548 (Pubitemid 43076543)
28. Kasperczyk S, Kasperczyk A, Ostalowska A, et al. Activity of glutathione peroxidase, glutathione reductase, and lipid peroxidation in erythrocytesin workers exposed to lead. Biol Trace Elem Res. 2004 ; 102: 61-72 (Pubitemid 40105007)
29. Toxicological profile for lead. (Draft for Public Comment). Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service ; 2005: 43-59.
30. El-Sayed AMA and Fouzy ASM. Effect of Lead Administration on Some Blood Biochemical Parameters. 3rd ed. CTOX-DC, OS 7.2.. 1995 :
31. Tandon SK, Snigh S, Prasad S, Mathur N. Influence of l-lysine and zinc administration during exposure to lead or lead and ethanol in rats. Biol Trace Elements Res. 1997 ; 57: 51-58 (Pubitemid 27323564)
32. Skoczynska A, Smolik R. The effect of combined exposure to lead and cadmium on serum lipids and lipid peroxides level in rats. Int Occup Med Environ Health. 1994 ; 7: 263-271 (Pubitemid 24374399)
33. Antonowicz J, Andrzejak R, Lepetow T, Skoczynska A, Smolik R. Blood lipid parameters in smelters chronically exposed to heavy metals. Med Pr. 1996 ; 47: 207-215
34. Staessen JA, Roels H, Lauwerys RR, Amery A. Low-level lead exposure and blood pressure. J Hum Hypertens. 1995 ; 9: 303-328
35. Vaziri ND, Sica DA. Lead-induced hypertension: role of oxidative stress. Curr Hypertens Rep. 2004 ; 6: 314-320 (Pubitemid 39144657)
36. Vaziri ND, Wang XQ, Oveisi F, Rad B. Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension. 2000 ; 36: 142-146 (Pubitemid 30602167)