-
1
-
-
0035692769
-
Ewing tumour: Incidence, prognosis and treatment options
-
Paulussen M, Frohlich B, Jurgens H. Ewing tumour: incidence, prognosis and treatment options. Paediatr Drugs 2001;3:899-913. (Pubitemid 34074816)
-
(2001)
Pediatric Drugs
, vol.3
, Issue.12
, pp. 899-913
-
-
Paulussen, M.1
Frohlich, B.2
Jurgens, H.3
-
2
-
-
70149105476
-
Ewing's sarcoma: Standard and experimental treatment options
-
Subbiah V, Anderson P, Lazar AJ, Burdett E, Raymond K, Ludwig JA. Ewing's sarcoma: standard and experimental treatment options. Curr Treat Options Oncol 2009;10:126-40.
-
(2009)
Curr Treat Options Oncol
, vol.10
, pp. 126-140
-
-
Subbiah, V.1
Anderson, P.2
Lazar, A.J.3
Burdett, E.4
Raymond, K.5
Ludwig, J.A.6
-
3
-
-
64249135764
-
Novel agents on the horizon for cancer therapy
-
Ma WW, Adjei AA. Novel agents on the horizon for cancer therapy. CA Cancer J Clin 2009;59:111-37.
-
(2009)
CA Cancer J Clin
, vol.59
, pp. 111-137
-
-
Ma, W.W.1
Adjei, A.A.2
-
4
-
-
70349753195
-
Advances in Ewing's sarcoma research: Where are we now and what lies ahead?
-
Ordonez JL, Osuna D, Herrero D, de Alava E, Madoz-Gurpide J. Advances in Ewing's sarcoma research: where are we now and what lies ahead? Cancer Res 2009;69:7140-50.
-
(2009)
Cancer Res
, vol.69
, pp. 7140-7150
-
-
Ordonez, J.L.1
Osuna, D.2
Herrero, D.3
De Alava, E.4
Madoz-Gurpide, J.5
-
5
-
-
0029829794
-
EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro
-
Kovar H, Aryee DN, Jug G, Henockl C, Schemper M, Delattre O, et al. EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro. Cell Growth Differ 1996;7:429-37. (Pubitemid 26362087)
-
(1996)
Cell Growth and Differentiation
, vol.7
, Issue.4
, pp. 429-437
-
-
Kovar, H.1
Aryee, D.N.T.2
Jug, G.3
Henockl, C.4
Schemper, M.5
Delattre, O.6
Thomas, G.7
Gadner, H.8
-
6
-
-
0031025207
-
EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells
-
Tanaka K, Iwakuma T, Harimaya K, Sato H, Iwamoto Y. EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells. J Clin Invest 1997;99:239-47. (Pubitemid 27053464)
-
(1997)
Journal of Clinical Investigation
, vol.99
, Issue.2
, pp. 239-247
-
-
Tanaka, K.1
Iwakuma, T.2
Harimaya, K.3
Sato, H.4
Iwamoto, Y.5
-
7
-
-
0034694834
-
EWS Fli-1 antisense nanocapsules inhibits Ewing sarcoma-related tumor in mice
-
DOI 10.1006/bbrc.2000.3963
-
Lambert G, Bertrand JR, Fattal E, Subra F, Pinto-Alphandary H, Malvy C, et al. EWS fli-1 antisense nanocapsules inhibits Ewing sarcomarelated tumor in mice. Biochem Biophys Res Commun 2000;279:401-6. (Pubitemid 32016729)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.279
, Issue.2
, pp. 401-406
-
-
Lambert, G.1
Bertrand, J.R.2
Fattal, E.3
Subra, F.4
Pinto-Alphandary, H.5
Malvy, C.6
Auclair, C.7
Couvreur, P.8
-
8
-
-
77955729370
-
Oncogenic partnerships: EWSFLI1 protein interactions initiate key pathways of Ewing's sarcoma
-
Erkizan HV, Uversky VN, Toretsky JA. Oncogenic partnerships: EWSFLI1 protein interactions initiate key pathways of Ewing's sarcoma. Clin Cancer Res 2010;16:4077-83.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4077-4083
-
-
Erkizan, H.V.1
Uversky, V.N.2
Toretsky, J.A.3
-
9
-
-
0030695913
-
The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts
-
DOI 10.1074/jbc.272.49.30822
-
Toretsky JA, Kalebic T, Blakesley V, LeRoith D, Helman LJ. The insulinlike growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblasts. J Biol Chem 1997;272:30822-7. (Pubitemid 27527522)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.49
, pp. 30822-30827
-
-
Toretsky, J.A.1
Kalebic, T.2
Blakesley, V.3
LeRoith, D.4
Helman, L.J.5
-
10
-
-
0025632981
-
Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor
-
Yee D, Favoni RE, Lebovic GS, Lombana F, Powell DR, Reynolds CP, et al. Insulin-like growth factor I expression by tumors of neuroectodermal origin with the t(11;22) chromosomal translocation. A potential autocrine growth factor. J Clin Invest 1990;86:1806-14.
-
(1990)
J Clin Invest
, vol.86
, pp. 1806-1814
-
-
Yee, D.1
Favoni, R.E.2
Lebovic, G.S.3
Lombana, F.4
Powell, D.R.5
Reynolds, C.P.6
-
11
-
-
0029838475
-
Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: A possible therapeutic target
-
Scotlandi K, Benini S, Sarti M, Serra M, Lollini PL, Maurici D, et al. Insulin-like growth factor I receptor-mediated circuit in Ewing's sarcoma/peripheral neuroectodermal tumor: a possible therapeutic target. Cancer Res 1996;56:4570-4. (Pubitemid 26338048)
-
(1996)
Cancer Research
, vol.56
, Issue.20
, pp. 4570-4574
-
-
Scotlandi, K.1
Benini, S.2
Sarti, M.3
Serra, M.4
Lollini, P.-L.5
Maurici, D.6
Picci, P.7
Manara, M.C.8
Baldini, N.9
-
12
-
-
77955661924
-
Recent advances in the molecular pathogenesis of Ewing's sarcoma
-
Toomey EC, Schiffman JD, Lessnick SL. Recent advances in the molecular pathogenesis of Ewing's sarcoma. Oncogene 2010;29:4504-16.
-
(2010)
Oncogene
, vol.29
, pp. 4504-4516
-
-
Toomey, E.C.1
Schiffman, J.D.2
Lessnick, S.L.3
-
13
-
-
56749110996
-
The type 1 insulin-like growth factor receptor pathway
-
Chitnis MM, Yuen JS, Protheroe AS, Pollak M, Macaulay VM. The type 1 insulin-like growth factor receptor pathway. Clin Cancer Res 2008;14:6364-70.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6364-6370
-
-
Chitnis, M.M.1
Yuen, J.S.2
Protheroe, A.S.3
Pollak, M.4
Macaulay, V.M.5
-
15
-
-
0032838772
-
DNA protein cross-links produced by NSC 652287, a novel thiophene derivative active against human renal cancer cells
-
Nieves-Neira W, Rivera MI, Kohlhagen G, Hursey ML, Pourquier P, Sausville EA, et al. DNA protein cross-links produced by NSC 652287, a novel thiophene derivative active against human renal cancer cells. Mol Pharmacol 1999;56:478-84. (Pubitemid 29406874)
-
(1999)
Molecular Pharmacology
, vol.56
, Issue.3
, pp. 478-484
-
-
Nieves-Neira, W.1
Rivera, M.I.2
Kohlhagen, G.3
Hursey, M.L.4
Pourquier, P.5
Sausville, E.A.6
Pommier, Y.7
-
16
-
-
11144315535
-
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
-
DOI 10.1038/nm1146
-
Issaeva N, Bozko P, Enge M, Protopopova M, Verhoef LG, Masucci M, et al. Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nat Med 2004;10:1321-8. (Pubitemid 40022713)
-
(2004)
Nature Medicine
, vol.10
, Issue.12
, pp. 1321-1328
-
-
Issaeva, N.1
Bozko, P.2
Enge, M.3
Protopopova, M.4
Verhoef, L.G.G.C.5
Masucci, M.6
Pramanik, A.7
Selivanova, G.8
-
17
-
-
26244440782
-
Targeting MDM2 by the small molecule RITA: Towards the development of new multi-target drugs against cancer
-
Espinoza-Fonseca LM. Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer. Theor Biol Med Model 2005;2:38.
-
(2005)
Theor Biol Med Model
, vol.2
, pp. 38
-
-
Espinoza-Fonseca, L.M.1
-
18
-
-
77953562379
-
Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA
-
Zhao CY, Grinkevich VV, Nikulenkov F, Bao W, Selivanova G. Rescue of the apoptotic-inducing function of mutant p53 by small molecule RITA. Cell Cycle 2010;9:1847-55.
-
(2010)
Cell Cycle
, vol.9
, pp. 1847-1855
-
-
Zhao, C.Y.1
Grinkevich, V.V.2
Nikulenkov, F.3
Bao, W.4
Selivanova, G.5
-
19
-
-
77953592090
-
Improving pharmacological rescue of p53 function: RITA targets mutant p53
-
Girardini JE, Del Sal G. Improving pharmacological rescue of p53 function: RITA targets mutant p53. Cell Cycle 2010;9:1847-55.
-
(2010)
Cell Cycle
, vol.9
, pp. 1847-1855
-
-
Girardini, J.E.1
Del Sal, G.2
-
20
-
-
0002952791
-
Ewing's sarcoma family of tumors
-
Masters JRW, Palsson B, editors. The Netherlands: Kluwer Academic Publisher
-
Van Valen F. Ewing's sarcoma family of tumors. In:Masters JRW, Palsson B, editors. Human cell culture vol I. The Netherlands: Kluwer Academic Publisher; 1999. p. 55-85.
-
(1999)
Human Cell Culture
, vol.1
, pp. 55-85
-
-
Van Valen, F.1
-
21
-
-
0025043497
-
Establishment and characterization of a primitive neuroectodermal tumor of bone continuous cell line (LAP-35)
-
Bagnara GP, Serra M, Giovannini M, Badiali M, Stella M, Montaldi A, et al. Establishment and characterization of a primitive neuroectodermal tumor of bone continuous cell line (LAP-35). Int J Cell Cloning 1990;8:409-24. (Pubitemid 20359751)
-
(1990)
International Journal of Cell Cloning
, vol.8
, Issue.6
, pp. 409-424
-
-
Bagnara, G.P.1
Serra, M.2
Giovannini, M.3
Badiali, M.4
Stella, M.5
Montaldi, A.6
Granchi, D.7
Paolucci, P.8
Rocchi, P.9
Pession, A.10
Picci, P.11
Paolucci, G.12
Campanacci, M.13
Tessarollo, L.14
Cavazzana, A.O.15
-
22
-
-
74949090294
-
Molecular characterization of commonly used cell lines for bone tumor research: A trans-European EuroBoNet effort
-
Ottaviano L, Schaefer KL, Gajewski M, Huckenbeck W, Baldus S, Rogel U, et al. Molecular characterization of commonly used cell lines for bone tumor research: a trans-European EuroBoNet effort. Genes Chromosomes Cancer 2010;49:40-51.
-
(2010)
Genes Chromosomes Cancer
, vol.49
, pp. 40-51
-
-
Ottaviano, L.1
Schaefer, K.L.2
Gajewski, M.3
Huckenbeck, W.4
Baldus, S.5
Rogel, U.6
-
23
-
-
0026530821
-
Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines
-
Davidoff AM, Pence JC, Shorter NA, Iglehart JD, Marks JR. Expression of p53 in human neuroblastoma- and neuroepithelioma-derived cell lines. Oncogene 1992;7:127-33.
-
(1992)
Oncogene
, vol.7
, pp. 127-133
-
-
Davidoff, A.M.1
Pence, J.C.2
Shorter, N.A.3
Iglehart, J.D.4
Marks, J.R.5
-
24
-
-
73349085544
-
Interactions between MDM2 and TP53 genetic alterations, and their impact on response to MDM2 inhibitors and other chemotherapeutic drugs in cancer cells
-
Liu W, He L, Ramirez J, Ratain MJ. Interactions between MDM2 and TP53 genetic alterations, and their impact on response to MDM2 inhibitors and other chemotherapeutic drugs in cancer cells. Clin Cancer Res 2009;15:7602-7.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7602-7607
-
-
Liu, W.1
He, L.2
Ramirez, J.3
Ratain, M.J.4
-
25
-
-
0033152250
-
Selective toxicity of the tricyclic thiophene NSC 652287 in renal carcinoma cell lines Differential accumulation and metabolism
-
DOI 10.1016/S0006-2952(99)00046-5, PII S0006295299000465
-
Rivera MI, Stinson SF, Vistica DT, Jorden JL, Kenney S, Sausville EA. Selective toxicity of the tricyclic thiophene NSC 652287 in renal carcinoma cell lines: differential accumulation and metabolism. Biochem Pharmacol 1999;57:1283-95. (Pubitemid 29185150)
-
(1999)
Biochemical Pharmacology
, vol.57
, Issue.11
, pp. 1283-1295
-
-
Rivera, M.I.1
Stinson, S.F.2
Vistica, D.T.3
Jorden, J.L.4
Kenney, S.5
Sausville, E.A.6
-
26
-
-
0034351716
-
Murine model for skeletal metastases of Ewing's sarcoma
-
Scotlandi K, Benini S, Manara MC, Serra M, Nanni P, Lollini PL, et al. Murine model for skeletal metastases of Ewing's sarcoma. J Orthop Res 2000;18:959-66.
-
(2000)
J Orthop Res
, vol.18
, pp. 959-966
-
-
Scotlandi, K.1
Benini, S.2
Manara, M.C.3
Serra, M.4
Nanni, P.5
Lollini, P.L.6
-
27
-
-
22044434446
-
Role of insulin-like growth factor I receptor signalling in cancer
-
DOI 10.1038/sj.bjc.6602627
-
Larsson O, Girnita A, Girnita L. Role of insulin-like growth factor 1 receptor signalling in cancer. Br J Cancer 2005;92:2097-101. (Pubitemid 40966242)
-
(2005)
British Journal of Cancer
, vol.92
, Issue.12
, pp. 2097-2101
-
-
Larsson, O.1
Girnita, A.2
Girnita, L.3
-
28
-
-
68049131458
-
HIPK2 regulation by MDM2 determines tumor cell response to the p53-reactivating drugs nutlin-3 and RITA
-
Rinaldo C, Prodosmo A, Siepi F, Moncada A, Sacchi A, Selivanova G, et al. HIPK2 regulation by MDM2 determines tumor cell response to the p53-reactivating drugs nutlin-3 and RITA. Cancer Res 2009;69:6241-8.
-
(2009)
Cancer Res
, vol.69
, pp. 6241-6248
-
-
Rinaldo, C.1
Prodosmo, A.2
Siepi, F.3
Moncada, A.4
Sacchi, A.5
Selivanova, G.6
-
29
-
-
80053934582
-
Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of Hdmx
-
Spinnler C, Hedstr€om E, Li H, de Lange J, Teunisse AF, Verlaan-de-Vries M, et al. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of Hdmx. Cell Death Differ 2011;18:1736-45.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1736-1745
-
-
Spinnler, C.1
Hedstrom, E.2
Li, H.3
De Lange, J.4
Teunisse, A.F.5
Verlaan-de-Vries, M.6
-
30
-
-
65449154815
-
Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis
-
Grinkevich VV, Nikulenkov F, Shi Y, Enge M, Bao W, Maljukova A, et al. Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis. Cancer Cell 2009;15:441-53.
-
(2009)
Cancer Cell
, vol.15
, pp. 441-453
-
-
Grinkevich, V.V.1
Nikulenkov, F.2
Shi, Y.3
Enge, M.4
Bao, W.5
Maljukova, A.6
-
31
-
-
78649645749
-
RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses
-
Saha MN, Jiang H, Mukai A, Chang H. RITA inhibits multiple myeloma cell growth through induction of p53-mediated caspase-dependent apoptosis and synergistically enhances nutlin-induced cytotoxic responses. Mol Cancer Ther 2010;9:3041-51.
-
(2010)
Mol Cancer Ther
, vol.9
, pp. 3041-3051
-
-
Saha, M.N.1
Jiang, H.2
Mukai, A.3
Chang, H.4
-
32
-
-
55849095485
-
Role of ubiquitination in IGF-1 receptor signaling and degradation
-
Sehat B, Andersson S, Vasilcanu R, Girnita L, Larsson O. Role of ubiquitination in IGF-1 receptor signaling and degradation. PLoS One 2007;2:e340.
-
(2007)
PLoS One
, vol.2
-
-
Sehat, B.1
Andersson, S.2
Vasilcanu, R.3
Girnita, L.4
Larsson, O.5
-
33
-
-
0242289370
-
In vitro downregulation of growth factors by insulin-like growth factor binding protein-3 in cervical cancer
-
DOI 10.1016/S0090-8258(03)00513-4
-
Mathur RS, Mathur SP. In vitro downregulation of growth factors by insulin-like growth factor binding protein-3 in cervical cancer. Gynecol Oncol 2003;91:410-5. (Pubitemid 37346337)
-
(2003)
Gynecologic Oncology
, vol.91
, Issue.2
, pp. 410-415
-
-
Mathur, R.S.1
Mathur, S.P.2
-
34
-
-
3543026281
-
EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3
-
DOI 10.1128/MCB.24.16.7275-7283.2004
-
Prieur A, Tirode F, Cohen P, Delattre O. EWS/FLI-1 silencing and gene profiling of Ewing cells reveal downstream oncogenic pathways and a crucial role for repression of insulin-like growth factor binding protein 3. Mol Cell Biol 2004;24:7275-83. (Pubitemid 39014452)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.16
, pp. 7275-7283
-
-
Prieur, A.1
Tirode, F.2
Cohen, P.3
Delattre, O.4
-
36
-
-
48649110734
-
Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis
-
Sehat B, Andersson S, Girnita L, Larsson O. Identification of c-Cbl as a new ligase for insulin-like growth factor-I receptor with distinct roles from Mdm2 in receptor ubiquitination and endocytosis. Cancer Res 2008;68:5669-77.
-
(2008)
Cancer Res
, vol.68
, pp. 5669-5677
-
-
Sehat, B.1
Andersson, S.2
Girnita, L.3
Larsson, O.4
-
37
-
-
60649103811
-
MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53
-
Enge M, Bao W, Hedström E, Jackson SP, Moumen A, Selivanova G. MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53. Cancer Cell 2009;15:171-83.
-
(2009)
Cancer Cell
, vol.15
, pp. 171-183
-
-
Enge, M.1
Bao, W.2
Hedström, E.3
Jackson, S.P.4
Moumen, A.5
Selivanova, G.6
-
38
-
-
0030666852
-
Transformed cells require continuous activity of RNA polymerase II to resist oncogene-induced apoptosis
-
Koumenis C, Giaccia A. Transformed cells require continuous activity of RNA polymerase II to resist oncogene-induced apoptosis. Mol Cell Biol 1997;17:7306-16. (Pubitemid 27505960)
-
(1997)
Molecular and Cellular Biology
, vol.17
, Issue.12
, pp. 7306-7316
-
-
Koumenis, C.1
Giaccia, A.2
-
39
-
-
21444432928
-
Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria
-
DOI 10.1074/jbc.M410691200
-
Arima Y, Nitta M, Kuninaka S, Zhang D, Fujiwara T, Taya Y, et al. Transcriptional blockade induces p53-dependent apoptosis associated with translocation of p53 to mitochondria. J Biol Chem 2005;280:19166-76. (Pubitemid 41379623)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19166-19176
-
-
Arima, Y.1
Nitta, M.2
Kuninaka, S.3
Zhang, D.4
Fujiwara, T.5
Taya, Y.6
Nakao, M.7
Saya, H.8
-
40
-
-
57049180854
-
The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor
-
Higashi Y, Sukhanov S, Parthasarathy S, Delafontaine P. The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor. Am J Physiol Heart Circ Physiol 2008;295:H1684-9.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
-
-
Higashi, Y.1
Sukhanov, S.2
Parthasarathy, S.3
Delafontaine, P.4
-
41
-
-
0022575813
-
Three alkaloids as selective destroyers of cancer cells in mice. Synergy with classic anticancer drugs
-
Beljanski M, Beljanski MS. Three alkaloids as selective destroyers of cancer cells in mice. Synergy with classic anticancer drugs. Oncology 1986;43:198-203. (Pubitemid 16121737)
-
(1986)
Oncology
, vol.43
, Issue.3
, pp. 198-203
-
-
Beljanski, M.1
Beljanski, M.S.2
-
42
-
-
40049085123
-
Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen
-
DOI 10.1177/1087057108315038
-
Sasiela CA, Stewart DH, Kitagaki J, Safiran YJ, Yang Y, Weissman AM, et al. Identification of inhibitors for MDM2 ubiquitin ligase activity from natural product extracts by a novel high-throughput electrochemiluminescent screen. J Biomol Screen 2008;13:229-37. (Pubitemid 351322873)
-
(2008)
Journal of Biomolecular Screening
, vol.13
, Issue.3
, pp. 229-237
-
-
Sasiela, C.A.1
Stewart, D.H.2
Kitagaki, J.3
Safiran, Y.J.4
Yang, Y.5
Weissman, A.M.6
Oberoi, P.7
Davydov, I.V.8
Goncharova, E.9
Beutler, J.A.10
McMahon, J.B.11
O'Keefe, B.R.12
-
43
-
-
0034708458
-
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
-
DOI 10.1074/jbc.275.12.8945
-
Fang S, Jensen JP,Ludwig RL, Vousden KH, Weissman AM. Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53. J Biol Chem 2000;275:8945-51. (Pubitemid 30180252)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.12
, pp. 8945-8951
-
-
Fang, S.1
Jensen, J.P.2
Ludwig, R.L.3
Vousden, K.H.4
Weissman, A.M.5
-
44
-
-
64649086259
-
Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and hypoxia
-
Yang J, Ahmed A, Poon E, Perusinghe N, de Haven BA, Box G, et al. Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell apoptosis in normoxia and hypoxia. Mol Cell Biol 2009;29:2243-53.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 2243-2253
-
-
Yang, J.1
Ahmed, A.2
Poon, E.3
Perusinghe, N.4
De Haven, B.A.5
Box, G.6
-
45
-
-
42249111043
-
Mutated and non-mutated TP53 as targets in the treatment of leukaemia
-
DOI 10.1111/j.1365-2141.2008.07046.x
-
Nahi H, Selivanova G, Lehmann S, Mollgard L, Bengtzen S, Concha H, et al. Mutated and non-mutated TP53 as targets in the treatment of leukaemia. Br J Haematol 2008;141:445-53. (Pubitemid 351550548)
-
(2008)
British Journal of Haematology
, vol.141
, Issue.4
, pp. 445-453
-
-
Nahi, H.1
Selivanova, G.2
Lehmann, S.3
Mollgard, L.4
Bengtzen, S.5
Concha, H.6
Svensson, A.7
Wiman, K.G.8
Merup, M.9
Paul, C.10
-
46
-
-
21644463635
-
beta-arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth Factor-1 receptor by acting as adaptor for the MDM2 E3 ligase
-
DOI 10.1074/jbc.M501129200
-
Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Girnita A, Lefkowitz RJ, et al. {beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. J Biol Chem 2005;280:24412-9. (Pubitemid 40934525)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.26
, pp. 24412-24419
-
-
Girnita, L.1
Shenoy, S.K.2
Sehat, B.3
Vasilcanu, R.4
Girnita, A.5
Lefkowitz, R.J.6
Larsson, O.7
-
47
-
-
53649093334
-
Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival
-
Froment P, Dupont J, Christophe-Marine J. Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival. Cell Cycle 2008;7:3098-103.
-
(2008)
Cell Cycle
, vol.7
, pp. 3098-3103
-
-
Froment, P.1
Dupont, J.2
Christophe-Marine, J.3
-
48
-
-
84858005791
-
1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma
-
Mackintosh C, Ordóñez JL, García-Domínguez DJ, Sevillano V, Llombart- Bosch A, Szuhai K, et al. 1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcoma. Oncogene 2012;31:1287-98.
-
(2012)
Oncogene
, vol.31
, pp. 1287-1298
-
-
Mackintosh, C.1
Ordóñez, J.L.2
García-Domínguez, D.J.3
Sevillano, V.4
Llombart-Bosch, A.5
Szuhai, K.6
-
49
-
-
0345824732
-
Cell Cycle Regulatory Functions of the Human Oncoprotein MDM2
-
Deb SP. Cell cycle regulatory functions of the human oncoprotein MDM2. Mol Cancer Res 2003;1:1009-16. (Pubitemid 38044976)
-
(2003)
Molecular Cancer Research
, vol.1
, Issue.14
, pp. 1009-1016
-
-
Deb, S.P.1
-
50
-
-
20044367805
-
Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: A highly lethal subset associated with poor chemoresponse
-
DOI 10.1200/JCO.2005.02.081
-
Huang H-Y, Illei PB, Zhao Z, Mazumdar M, Huvos AG, Healey JH, et al. Ewing sarcomas with p53 mutation or 16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponse. J Clin Oncol 2005;23:548-58. (Pubitemid 46224232)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.3
, pp. 548-558
-
-
Huang, H.-Y.1
Illei, P.B.2
Zhao, Z.3
Mazumdar, M.4
Huvos, A.G.5
Healey, J.H.6
Wexler, L.H.7
Gorlick, R.8
Meyers, P.9
Ladanyi, M.10
|