Radio-modulatory effects of Green Tea Catechin EGCG on pBR322 plasmid DNA and murine splenocytes against gamma-radiation induced damage

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 747, Issue 1, 2012, Pages 62-70

  Richi, Benila ^a   Kale, Raosaheb K ^b   Tiku, Ashu B ^a  

^a JAWAHARLAL NEHRU UNIVERSITY   (India)

^b CENTRAL UNIVERSITY OF GUJARAT   (India)

Author keywords

Antioxidant; DNA damage; Epigallocatechin 3 gallate; Gamma radiation; Polyphenols; Radioprotection

Indexed keywords

ASCORBIC ACID; EPIGALLOCATECHIN GALLATE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LACTATE DEHYDROGENASE; PLASMID DNA; QUERCETIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA STRAND BREAKAGE; DRUG EFFECT; ENZYME ACTIVITY; GAMMA IRRADIATION; LIPID PEROXIDATION; MALE; MEMBRANE DAMAGE; MEMBRANE FLUIDITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; RADIATION PROTECTION; SPLEEN CELL;

ANIMALS; ANTIMUTAGENIC AGENTS; ANTIOXIDANTS; CATECHIN; CELL DEATH; DNA DAMAGE; GAMMA RAYS; LIPID PEROXIDATION; MICE; RADIATION-PROTECTIVE AGENTS; SPLEEN; TEA;

MURINAE;

EID: 84862333848     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2012.04.002     Document Type: Article

References (59)

1. Moores B.M., Regulla D. A review of the scientific basis for radiation protection of the patient. Radiat. Prot. Dosimetry 2011, 147:22-29.
2. Mobbs S.F., Muirhead C.R., Harrison J.D. Risks from ionising radiation: an HPA viewpoint paper for safegrounds. J. Radiol. Prot. 2011, 31:289-307.
3. Weiss J.F., Landauer M.R. Protection against ionizing radiation by antioxidant nutrients and phytochemicals. Toxicology 2003, 189:1-20.
4. Arora R., Gupta D., Chawla R., Sagar R., Sharma A., Kumar R., Prasad J., Singh S., Samanta N., Sharma R.K. Radioprotection by plant products: present status and future prospects. Phytother. Res. 2005, 19:1-22.
5. Citrin D., Cotrim A.P., Hyodo F., Baum B.J., Krishna M.C., Mitchell J.B. Radioprotectors and mitigators of radiation-induced normal tissue injury. Oncologist 2010, 15:360-371.
6. Ullah M.F., Khan M.W. Food as medicine: potential therapeutic tendencies of plant derived polyphenolic compounds. Asian Pac. J. Cancer Prev. 2008, 9:187-195.
7. Suganuma M., Saha A., Fujiki H. New cancer treatment strategy using combination of green tea catechins and anticancer drugs. Cancer Sci. 2011, 102:317-323.
8. Lambert J.D., Elias R.J. The antioxidant and pro-oxidant activities of green tea polyphenols: a role in cancer prevention. Arch. Biochem. Biophys. 2010, 501:65-72.
9. Singh R., Akhtar N., Haqqi T.M. Green tea polyphenol epigallocatechin-3-gallate: inflammation and arthritis. Life Sci. 2010, 86:907-918.
10. Fujiki H., Green Tea Health benefits as cancer preventive for humans. The Chemical Record 2005, 5:119-132.
11. Mejia E.G.Z., Ramirez-Mares M.V., Puangpraphant S. Bioactive components of tea: Cancer, inflammation and behavior. Brain Behav. Immun. 2009, 23:721-731.
12. Lee M.H., Han D.W., Hyon S.H., Park J.C. Apoptosis of human fibrosarcoma HT-1080 cells by epigallocatechin-3-O-gallate via induction of p53 and caspases as well as suppression of Bcl-2 and phosphorylated nuclear factor-κB. Apoptosis 2011, 16:75-85.
13. Rice-Evans C. Implications of the mechanisms of action of tea polyphenols as antioxidants in vitro for chemoprevention in humans. Proc. Soc. Exp. Biol. Med. 1999, 220:262-266.
14. Qi X. Reactive oxygen species scavenging activities and inhibition on DNA oxidative damage of dimeric compounds from the oxidation of (-)-epigallocatechin-3-O-gallate. Fitoterapia 2010, 81:205-209.
15. Yoshioka H., Kurosaki H., Yoshinaga K., Saito K., Yoshioka H. Beta ray-induced scission of DNA in tritiated water and protection by a green tea percolate and (-)-epigallocatechin gallate. Biosci. Biotechnol. Biochem. 1997, 61:1560-1563.
16. Yoshioka H., Akai G., Yoshinaga K., Hasegawa K., Yoshioka H. Protecting effect of a green tea percolate and its main constituents against gamma ray-induced scission of DNA. Biosci. Biotechnol. Biochem. 1996, 60:117-119.
17. Katiyar S.K., Challa A., McCormick T.S., Cooper K.D., Mukhtar H. Prevention of UVB-induced immunosuppression in mice by the green tea polyphenol (-)-epigallocatechin-3-gallate may be associated with alterations in IL-10 and IL-12 production. Carcinogenesis 1999, 20:2117-2124.
18. Katiyar S.K. Green tea prevents non-melanoma skin cancer by enhancing DNA repair. Arch. Biochem. Biophys. 2011, 508:152-158.
19. Kondo H., Park S.H., Watanabe K., Yamamoto Y., Akashi M. Polyphenol (-)-epigallocatechin gallate inhibits apoptosis induced by irradiation in human HaCaT keratinocytes. Biochem. Biophys. Res. Commun. 2004, 316:59-64.
20. Guo S., Hu Y., Liu P., Wang Y., Guo D., Wang D., Liao H. Protective activity of different concentration of tea polyphenols and its major compound EGCG against whole body irradiation-induced injury in mice. Zhongguo Zhong Yao Za Zhi 2010, 35:1328-1331.
21. Lee H.J., Kim J.S., Moon C., Kim J.C., Lee Y.S., Jang J.S., Jo S.K., Kim S.H. Modification of gamma-radiation response in mice by green tea polyphenols. Phytother. Res. 2008, 22:1380-1383.
22. Yamamoto T., Staples J., Wataha J., Lewis J., Lockwood P., Schoenlein P., Rao S., Osaki T., Dickinson D., Kamatani T., Schuster G., Hsu S. Protective effects of EGCG on salivary gland cells treated with gamma-radiation or cis-platinum(II)diammine dichloride. Anticancer Res. 2004, 24:3065-3073.
23. Yang H., Zonder J.A., Dou Q.P. Clinical development of novel proteasome inhibitors for cancer treatment. Expert. Opin. Investig. Drugs 2009, 18:957-971.
24. Baatout S., Derradji H., Jacquet P., Mergeay M. Increased radiation sensitivity of an eosinophilic cell line following treatment with epigallocatechin-gallate, resveratrol and curcuma. Int. J. Mol. Med. 2005, 15:337-352.
25. Maurya D.K., Adhikari S., Nair C.K.K., Devasagayam T.P.A. DNA protective properties of vanillin against γ-radiation under different conditions: possible mechanisms. Mutat. Res. 2007, 634:69-80.
26. Haggerty D.F., Kalra V.K., Popjak G., Reynold E.E., Chiapelli F. Fluorescence polarization measurements on normal and mutant human skin fibroblasts. Arch. Biochem. Biophys. 1978, 189:51-62.
27. Singh N.P. Microgels for estimation of DNA strand breaks, DNA-protein cross links and apoptosis. Mutat. Res. 2000, 455:111-127.
28. Habig W.H., Pabst M.J., Jacoby W.B. Glutathione-S-transferase: the first enzymatic step in mercapturic acid formation. J. Biol. Chem. 1974, 249:7130-7139.
29. Marklund S., Marklund G. Involvement of superoxide anion radical in autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur. J. Biochem. 1974, 47:469-474.
30. Bergmeyer H.U., Bernt E. Lactic dehydrogenase. Meth. Enzym. Anal. 1974, 2:574-579.
31. Moron M.A., Dipierre I.W., Mannervick B. Levels of glutathione, glutathione reductase and glutathione-S- transferase activities in rat lung and liver. Biochim. Biophys. Acta 1979, 582:67-78.
32. Varshney R., Kale R.K. 1990, Effects of calmodulin antagonists on radiation-induced lipid peroxidation in microsomes. Int. J. Radiat. Biol. 1990, 58:533-543.
33. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with folin phenol reagent. J. Biol. Chem. 1951, 193:265-275.
34. Nakagawa T., Yokozawa T. Direct scavenging of nitric oxide and superoxide by green tea. Food Chem. Toxicol. 2002, 40:1745-1750.
35. Yang C.S., Wang X., Lu G., Picinich S.C. Cancer prevention by tea: animal studies, molecular mechanisms and human relevance. Nat. Rev. Cancer 2009, 9:429-439.
36. Parshad R., Sanford K.K., Price F.M., Steele V.E., Tarone R.E., Kelloff G.J., Boone C.W. Protective action of plant polyphenols on radiation-induced chromatid breaks in cultured human cells. Anticancer Res. 1998, 18:3263-3266.
37. Anderson R.F., Fisher L.J., Hara Y., Harris T., Mak W.B., Melton L.D., Packer J.E. Green tea catechins partially protect DNA from OH radical-induced strand breaks and base damage through fast chemical repair of DNA radicals. Carcinogenesis 2001, 22:1189-1193.
38. Katiyar S.K., Afaq F., Perez A., Mukhtar H. Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis 2001, 22:287-294.
39. Agrawal A., Kale R.K. Radiation induced peroxidative damage: mechanism and significance. Indian J. Exp. Biol. 2001, 39:209-291.
40. Srinivasan M., Sudheer A.R., Rajasekaran K.N., Menon V.P. Effect of curcumin analog on γ-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro. Chem. Biol. Interact. 2008, 176:1-8.
41. Benderitter M., Genod L.V., Berroud A., Muller S., Donner M., Voisin P. Radio-induced structural membrane modifications: a potential bioindicator of ionizing radiation exposure?. Int. J. Radiat. Biol. 1999, 75:1043-1053.
42. Cabrera C., Artacho R., Gimenez R. Beneficial effects of green tea-a review. J. Am. Coll. Nutr. 2006, 25:79-99.
43. Saffari Y., Sadrzadeh S.M. Green tea metabolite EGCG protects membranes against oxidative damage in vitro. Life Sci. 2004, 74:1513-1518.
44. Ohta Y., Kongo-Nishimura M., Matsura T., Yamada K., Kitagawa A., Kishikawa T. Melatonin prevents disruption of hepatic reactive oxygen species metabolism in rats treated with carbon tetrachloride. J. Pineal Res. 2004, 36:10-17.
45. Stadtman E.R. Protein oxidation and aging. Science 1992, 257:1220-1224.
46. Myhrstad M.C., Carlsen H., Nordstrom O., Blomhoff R., Moskaug J.Q. Flavonoids increase the intracellular glutathione level by transactivation of the γ-glutamylcysteine synthetase catalytical subunit promoter. Free Radic. Biol. Med. 2002, 32:386-393.
47. Na H.K., Surh Y.J. Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG. Food Chem. Toxicol. 2008, 46:1271-1278.
48. Yokozawa T., Dong E., Nakagawa T., Kashiwagi H., Nakagawa H., Takeuchi S., Chung H.Y. In vitro and in vivo studies on the radical-scavenging activity of tea. J. Agric. Food Chem. 1998, 46:2143-2150.
49. Frei B., Higdon J.V. Antioxidant activity of tea polyphenols in vivo: evidence from animal studies. J. Nutr. 2003, 133:3275S-3284S.
50. Hu Y., Guo D.H., Liu P., Cao J.J., Wang Y.P., Yin J., Zhu Y., Rahman K. Bioactive components from the tea polyphenols influence on endogenous antioxidant defense system and modulate inflammatory cytokines after total-body irradiation in mice. J. Phymed. 2011, 18:970-975.
51. Yamamoto T., Lewis J., Wataha J., Dickinson D., Singh B., Bollag W.B., Ueta E., Osaki T., Athar M., Schuster G., Hsu S. Roles of catalase and hydrogen peroxide in green tea polyphenol induced chemopreventive effects. J. Pharmacol. Exp. Ther. 2004, 308:317-323.
52. Ahmad N., Gupta S., Mukhtar H. Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kb in cancer cells versus normal cells. Arch. Biochem. Biophys. 2000, 376:338-346.
53. Chen Z.P., Schell J.B., Ho C.T., Chen K.Y. Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts. Cancer Lett. 1998, 129:173-179.
54. Yamamoto T., Hsu S., Lewis J., Wataha J., Dickinson D., Singh B., Bollag W.B., Lockwood P., Ueta E., Osaki T., Schuster G. Green tea polyphenol causes differential oxidative environments in tumor versus normal epithelial cells. J. Pharmacol. Exp. Ther. 2003, 307:230-236.
55. Jeong H.J., Kim E.M., Min J.J., Bom H.S., Kim Y.H., Jeong Y.D., Kim C.G. Differential effects of green tea polyphenol in the (-irradiation induced human leukemia and lymphoblastic cell damage. Korean J. Nucl. Med. 2003, 37:308-316.
56. Gibellini L., Pinti M., Nasi M., Montagna J.P., De Biasi S., Roat E., Bertoncelli L., Cooper E.L., Cossarizza A. Quercetin and cancer chemoprevention. Evid. Based Complement Alternat. Med. 2011, 2011:1-15.
57. Koyama S., Kodama S., Suzuki K., Matsumoto T., Miyazaki T., Watanabe M. Radiation-induced long-lived radicals which cause mutation and transformation. Mutat. Res. 1998, 421:45-54.
58. Noroozi M., Angerson W.J., Lean M.E. Effects of flavonoids and vitamin C on oxidative DNA damage to human lymphocytes. Am. J. Clin. Nutr. 1998, 67:1210-1218.
59. Johnson M.K., Loo G. Effects of epigallocatechin gallate and quercetin on oxidative damage to cellular DNA. Mutat. Res. 2000, 459:211-218.