Roles of Catalase and Hydrogen Peroxide in Green Tea Polyphenol-Induced Chemopreventive Effects

Journal of Pharmacology and Experimental Therapeutics

Volumn 308, Issue 1, 2004, Pages 317-323

  Yamamoto, Tetsuya ^a   Lewis, Jill ^b   Wataha, John ^b   Dickinson, Douglas ^b   Singh, Baldev ^b   Bollag, Wendy B ^b   Ueta, Eisaku ^a   Osaki, Tokio ^a   Athar, Mohammad ^c   Schuster, George ^b   Hsu, Stephen ^b  

^a KOCHI MEDICAL SCHOOL   (Japan)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CATALASE; EPIGALLOCATECHIN GALLATE; HYDROGEN PEROXIDE; POLYPHENOL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ARTICLE; CANCER INHIBITION; CANCER PREVENTION; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KERATINOCYTE; MITOCHONDRION; MOUTH CARCINOMA; OXIDATIVE STRESS; PRIORITY JOURNAL; TEA; WESTERN BLOTTING;

ACETYLCYSTEINE; CASPASE 3; CASPASES; CATALASE; CATECHIN; CELL DIVISION; CELL SURVIVAL; CHEMOPREVENTION; DRUG COMBINATIONS; ENZYME ACTIVATION; FLAVONOIDS; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; PHENOLS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TEA; TUMOR CELLS, CULTURED;

EID: 9144249568     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.103.058891     Document Type: Article

References (40)

1. Ahmad N, Gupta S, and Mukhtar H (2000) Green tea polyphenol epigallocatechin-3-gallate differentially modulates nuclear factor kappaB in cancer cells versus normal cells. Arch Biochem Biophys 376:338-346.
2. Balasubramanian S, Efimova T, and Eckert RL (2002) Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes. J Biol Chem 277:1828-1836.
3. Barthelman M, Bair WB, 3rd, Stickland KK, Chen W, Timmermann BN, Valcic S, Dong Z and Bowden GT (1998) (-)-Epigallocatechin-3-gallate inhibition of ultraviolet B-induced AP-1 activity. Carcinogenesis 19:2201-2204.
4. Chai PC, Long LH, and Halliwell B (2003) Contribution of hydrogen peroxide to the cytotoxicity of green tea and red wines. Biochem Biophys Res Commun 304:650-654.
5. Chen C, Shen G, Hebbar V, Hu R, Owuor ED, and Kong AN (2003) Epigallocatechin-3-gallate-induced stress signals in HT-29 human colon adenocarcinoma cells. Carcinogenesis 8:1369-78.
6. Chen C, Yu R, Owuor ED, and Kong AN (2000) Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKs) and caspases by major green tea polyphenol components during cell survival and death. Arch Pharm Res 23:605-612.
7. Chen L, Yang X, Jiao H, and Zhao B (2002) Tea catechins protect against lead-induced cytotoxicity, lipid peroxidation, and membrane fluidity in HepG2 cells. Toxicol Sci 69:149-156.
8. Chung JY, Huang C, Meng X, Dong Z, and Yang CS (1999) Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved. Cancer Res 59:4610-4617.
9. Dashwood WM, Orner GA, and Dashwood RH (2002) Inhibition of beta-catenin/Tcf activity by white tea, green tea, and epigallocatechin-3-gallate (EGCG): minor contribution of H(2)O(2) at physiologically relevant EGCG concentrations. Biochem Biophys Res Commun 296:584-588.
10. Dong Z, Ma W, Huang C, and Yang CS (1997) Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate, and theaflavins. Cancer Res 57:4414-4419.
11. Dong Z (2000) Effects of food factors on signal transduction pathways. Biofactors 12:17-28.
12. Gupta S, Ahmad N, Nieminen AL, and Mukhtar H (2000) Growth inhibition, cell-cycle dysregulation, and induction of apoptosis by green tea constituent (-)-epigallocatechin-3-gallate in androgen-sensitive and androgen-insensitive human prostate carcinoma cells. Toxicol Appl Pharmacol 164:82-90.
13. Gupta S, Hussain T, and Mukhtar H (2003) Molecular pathway for (-)-epigallocatechin-3-gallate-induced cell cycle arrest and apoptosis of human prostate carcinoma cells. Arch Biochem Biophys 410:177-185.
14. Halliwell B (2003) Oxidative stress in cell culture: an under-appreciated problem? FEBS Lett 540:3-6.
15. Higdon JV and Frei B (2003) Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions. Crit Rev Food Sci Nutr 43:89-143.
16. Hong J, Lu H, Meng X, Ryu JH, Hara Y, and Yang CS (2002) Stability, cellular uptake, biotransformation and efflux of tea polyphenol (-)-epigallocatechin-3-gallate in HT-29 human colon adenocarcinoma cells. Cancer Res 62:7241-7246.
17. Hsu S, Bollag WB, Lewis J, Huang Q, Singh B, Sharawy M, Yamamoto T, and Schuster G (2003a) Green tea polyphenols induce differentiation and proliferation in epidermal keratinocytes. J Pharmacol Exp Ther 306:29-34.
18. Hsu S, Lewis J, Singh B, Schoenlein P, Osaki T, Athar M, Porter AG, and Schuster G (2003b) Green tea polyphenol targets the mitochondria in tumor cells inducing caspase 3-dependent apoptosis. Anticancer Res 23:1533-1539.
19. Hsu S, Lewis JB, Borke JL, Singh B, Dickinson DP, Caughman GB, Athar M, Drake L, Aiken AC, Huynh CT et al. (2001) Chemopreventive effects of green tea polyphenols correlate with reversible induction of p57 expression. Anticancer Res 21:3743-3748.
20. Hsu S, Yu FS, Lewis J, Singh B, Borke J, Osaki T, Athar M, and Schuster G (2002a) Induction of p57 is required for cell survival when exposed to green tea polyphenols. Anticancer Res 22:4115-4120.
21. Hsu SD, Singh BB, Lewis JB, Borke JL, Dickinson DP, Drake L, Caughman GB, and Schuster GS (2002b) Chemoprevention of oral cancer by green tea. Gen Dent 50:140-146.
22. Jung YD and Ellis LM (2001) Inhibition of tumour invasion and angiogenesis by epigallocatechin gallate (EGCG), a major component of green tea. Int J Exp Pathol 82:309-316.
23. Katiyar SK and Elmets CA (2001) Green tea polyphenolic antioxidants and skin photoprotection (Review). Int J Oncol 18:1307-1313.
24. Kong AN, Yu R, Chen C, Mandlekar S, and Primiano T (2000) Signal transduction events elicited by natural products: role of MAPK and caspase pathways in homeostatic response and induction of apoptosis. Arch Pharm Res 23:1-16.
25. Kong AN, Yu R, Lei W, Mandlekar S, Tan TH, and Ucker DS (1998) Differential activation of MAPK and ICE/Ced-3 protease in chemical-induced apoptosis: the role of oxidative stress in the regulation of mitogen-activated protein kinases (MAPKs) leading to gene expression and survival or activation of caspases leading to apoptosis. Restor Neurol Neurosci 12:63-70.
26. Lee SR, Im KJ, Suh SI, and Jung JG (2003) Protective effect of green tea polyphenol (-)-epigallocatechin gallate and other antioxidants on lipid peroxidation in gerbil brain homogenates. Phytother Res 17:206-209.
27. Liang YC, Lin-Shiau SY, Chen CF, and Lin JK (1999) Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate. J Cell Biochem 75:1-12.
28. Liberto M and Cobrinik D (2000) Growth factor-dependent induction of p21(CIP1) by the green tea polyphenol, epigallocatechin gallate. Cancer Lett 154:151-161.
29. Lin JK, Liang YC, and Lin-Shiau SY (1999) Cancer chemoprevention by tea polyphenols through mitotic signal transduction blockade. Biochem Pharmacol 58: 911-915.
30. Long LH, Lan AN, Hsuan FT, and Halliwell B (1999) Generation of hydrogen peroxide by "antioxidant" beverages and the effect of milk addition. Is cocoa the best beverage? Free Radic Res Commun 31:67-71.
31. Nakagawa H, Wachi M, Woo JT, Kato M, Kasai S, Takahashi F, Lee IS, and Nagai K (2002) Fenton reaction is primarily involved in a mechanism of (-)-epigallocatechin-3-gallate to induce osteoclastic cell death. Biochem Biophys Res Commun 292:94-101.
32. Roy M, Chakrabarty S, Sinha D, Bhattacharya RK, and Siddiqi M (2003) Anticlastogenic, antigenotoxic and apoptotic activity of epigallocatechin gallate: a green tea polyphenol. Mutat Res 523-524:33-41.
33. Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Isemura M, and Yuo A (2002) Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis. Biochem J 368:705-720.
34. Sakagami H, Arakawa H, Maeda M, Satoh K, Kadofuku T, Fukuchi K, and Gomi K (2001) Production of hydrogen peroxide and methionine sulfoxide by epigallocatechin gallate and antioxidants. Anticancer Res 21:2633-2641.
35. Tanaka R (2000) Protective effects of (-)-epigallocatechin gallate and (+)-catechin on paraquat-induced genotoxicity in cultured cells. J Toxicol Sci 25:199-204.
36. Wei H, Zhang X, Zhao JF, Wang ZY, Bickers D, and Lebwohl M (1999) Scavenging of hydrogen peroxide and inhibition of ultraviolet light-induced oxidative DNA damage by aqueous extracts from green and black teas. Free Radic Biol Med 26:1427-1435.
37. Yamamoto T, Hsu S, Lewis J, Wataha J, Ueta E, Osaki T, Luckwood P, Singh B, Dickinson D, and Schuster G (2003) Green tea polyphenol creates differential oxidative environments in normal vs. malignant cells. J Pharmacol Exp Ther., in press.
38. Yang GY, Liao J, Kim K, Yurkow EJ, and Yang CS (1998) Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis 19:611-616.
39. Yang GY, Liao J, Li C, Chung J, Yurkow EJ, Ho CT, and Yang CS (2000) Effect of black and green tea polyphenols on c-jun phosphorylation and H(2)O(2) production in transformed and non-transformed human bronchial cell lines: possible mechanisms of cell growth inhibition and apoptosis induction. Carcinogenesis 21:2035-2039.
40. Zhu N, Huang TC, Yu Y, LaVoie EJ, Yang CS, and Ho CT (2000) Identification of oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin with H(2)O(2). J Agric Food Chem 48:979-981.