Effect of curcumin analog on γ-radiation-induced cellular changes in primary culture of isolated rat hepatocytes in vitro

Chemico-Biological Interactions

Volumn 176, Issue 1, 2008, Pages 1-8

  Srinivasan, M ^a   Sudheer, A Ram ^a   Rajasekaran, K N ^b   Menon, Venugopal P ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b UNIVERSITY OF KERALA   (India)

Author keywords

Radiation; Comet assay; Curcumin analog; DNA damage; Hepatocytes; Lipid peroxidation

Indexed keywords

BIS 1,7 (2 HYDROXYPHENYL)HEPTA 1,6 DIENE 3,5 DIONE; COLLAGENASE; CURCUMIN; CURCUMIN DERIVATIVE; GLUTATHIONE; PHENOL DERIVATIVE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROTECTION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; DRUG STRUCTURE; ENZYME ACTIVITY; GAMMA RADIATION; IN VITRO STUDY; LIPID PEROXIDATION; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; RAT;

ANIMALS; ANTIOXIDANTS; CATALASE; CELL SEPARATION; CELLS, CULTURED; CURCUMIN; DNA DAMAGE; GAMMA RAYS; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HEPATOCYTES; HYDROGEN BONDING; MALE; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 52949147778     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.03.006     Document Type: Article

References (40)

1. Jagetia G.C., Rajanikant G.K., Rao S.K., and Shrinath Baliga M. Alteration in the glutathione, glutathione peroxidase, superoxide dismutase and lipid peroxidation by ascorbic acid in the skin of mice exposed to fractionated γ-radiation. Clin. Chim. Acta 332 (2003) 111-121
2. Jagetia G.C., and Reddy T.K. Modulation of radiation induced alterations in the antioxidant status of mice by naringin. Life Sci. 77 (2005) 780-794
3. Nair C.K.K., Parida D.K., and Noumra T. Radioprotectors in radiotherapy. J. Radiat. Res. 42 (2001) 21-37
4. Von Sonntag. The Chemical Basis of Radiation Biology (1987), Taylor and Francis, London
5. Spotheim-Maurizot M., Gariner F., Sabattier R., and Charlier M. Metal ions protects DNA against strand breakage induced by fast neutrons. Int. J. Radiat. Biol. 62 (1992) 659-666
6. Agrawal A., and Kale R.K. Radiation induced peroxidative damage: mechanism and significance. Indian J. Exp. Biol. 39 4 (2001) 209-291
7. Rajendra Prasad N., Menon V.P., Vasudev V., and Pugalendi K.V. Radioprotective effect of seasamol on γ-radiation induced DNA damage, lipid peroxidation and antioxidants level in cultured human lymphocytes. Toxicology 209 (2005) 225-235
8. Pandey B.N., and Mishra K.P. Fluorescence and ESR studies on membrane oxidative damage by γ-radiation. Appl. Magn. Reson. 18 (2000) 483-492
9. Anto R.J., George J., Dinesh Babu K.V., Rajasekharan K.N., and Kuttan R. Antimutagenic and anticarcinogenic activity of natural and synthetic curcuminoids. Mutat. Res. 370 (1996) 127-131
10. Srinivasan A., Menon V.P., Periyasamy V., and Rajasekaran K.N. Protection of pancreatic β-cell by the potential antioxidant bis-o-hydroxycinnamoyl methane, analogue of natural curcuminoid in experimental diabetes. J. Pharm. Pharm. Sci. 6 3 (2003) 327-333
11. Rukkumani R., Aruna K., Suresh Varma P., and Menon V.P. Protective role of a novel curcuminoid on alcohol and PUFA-induced hyperlipidemia. Toxicol. Mech. Methods 15 (2005) 227-234
12. Devasena T., Rajasekaran K.N., and Menon V.P. Bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione (a curcumin analog) ameliorates DMH-induced hepatic oxidative stress during colon carcinogenesis. Pharmacol. Res. 46 (2002) 39-45
13. Dinesh Babu K.V., and Rajasekaran K.N. Simplified conditions for the synthesis of curcumin 1 and other curcuminoids. Org. Prep. Proced. Int. 26 (1994) 674-677
14. Santhosh A., Mathew S., and Sudhakaran P.R. Synthesis of sulphated proteoglycans by primary cultures of rat hepatocyte modulation by matrix substratum. Mol. Cell. Biochem. 165 1 (1996) 1-7
15. Singh N.P. Microgels for estimation of DNA strand break DNA protein crosslink and apoptosis. Mutat. Res. 455 (2000) 111-127
16. Niehaus W.G., and Samuelsson B. Formation of malondialdehyde from phospholipid arachidonate during microsomal lipid peroxidation. Eur. J. Biochem. 6 (1968) 126-130
17. Ellman G.L. Tissue sulphydryl groups. Arch. Biochem. Biophys. 82 (1959) 70-77
18. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin-phenol reagent. J. Biol. Chem. 193 1 (1951) 265-275
19. Kakkar P., Das B., and Viswanathan P.N. A modified spectrophotometric assay of superoxide dismutase. Indian J. Biochem. Biophys. 21 2 (1984) 130-132
20. Sinha K.A. Colorimetric assay of catalase. Anal. Biochem. 47 (1972) 389-394
21. Rotruck J.T., Pope A.L., Gauther H.E., Swanson A.B., and Hofeman D.G. Selenium biochemical roles as a component of glutathione peroxidase. Science 179 (1973) 588-590
22. Grinda D.J., Murley J.S., and Kataoka Y. Radioprotectants: current status and new directions. Oncology 63 2 (2002) 2-10
23. Hui Z., Naikum Z., Rang Z., Xiumin L., and Huifang C. Effect of ionizing radiation on bio-oxidase activities in cytoplasm of mouse blood liver cells. Chin. J. Radiat. Med. Prot. 16 3 (1996) 179-182
24. Kamat J.P., Boloor K.K., Devasagayam T.P.A., and Venkatachalam S.R. Antioxidant properties of Asparaguss racemous against damage induced by γ-radiation in rat liver mitochondria. J. Ethnopharmacol. 71 (2000) 425-435
25. Turner N.D., Braby L.A., Ford J., and Lupton J.R. Opportunities for nutritional amelioration of radiation-induced cellular damage. Nutrition 18 (2002) 904-912
26. Ohata Y., Kongo-Nishimura M., Matsura T., Yamada K., Kitagawa A., and Kishikawa T. Melatonin prevents disruption of hepatic reactive oxygen species metabolism in rats treated with carbon tetrachloride. J. Pineal Res. 36 (2004) 10-17
27. Halliwell B. Effect of diet on cancer development: is oxidative DNA damage a biomarker?. Free Radic. Biol. Med. 32 (2002) 968-974
28. Riley P.A. Free radicals in biology: oxidative stress and the effect of ionizing radiation. Int. J. Radiat. Biol. 65 (1994) 27-33
29. Indira Priyadarsini K. Free radical reactions of curcumin in membrane models. Free Radic. Biol. Med. 23 6 (1997) 838-843
30. Khopde S.M., Priyadarsini K.I., Guha S.N., Satav J.G., Venkatesan P., and Rao M.N. Inhibition of radiation-induced lipid peroxidation by tetrahydro curcumin: possible mechanism by pulse radiolysis. Biosci. Biotechnol. Biochem. 64 3 (2000) 503-509
31. Rukkumani R., Aruna K., Varma P.S., Rajasekaran K.N., and Menon V.P. Comparative effects of curcumin and an analog of curcumin on alcohol and PUFA induced oxidative stress. J. Pharm. Pharm. Sci. 7 2 (2004) 274-283
32. Pan G.X., Spencer L., and Leary G.J. Reactivity of ferulic acid and its derivative towards hydrogen peroxide and peracetic acid. J. Agric. Food Chem. 47 (1999) 3325-3331
33. Sreejayan, and Rao M.N. Nitric oxide scavenging by curcuminoids. J. Pharm. Pharmacol. 49 (1997) 105-107
34. Subramanian M., Sreejayan, Rao M.N., Devasagayam T.P., and Singh B.B. Diminution of singlet oxygen-induced DNA damage by curcumin and related antioxidants. Mutat. Res. 311 21 (1994) 249-255
35. Polasa K., Naidu A.N., Ravindranath I., and Krishanaswamy K. Inhibition of B(a)P induced strand breaks in presence of curcumin. Mutat. Res. 557 2 (2004) 203-213
36. 3+ on curcumin-induced chromosomal aberrations in CHO cells. Genet. Mol. Biol. 28 (2005) 161-164
37. Lodovici M., Raimondi L., Guglielmi F., Gemignani S., and Dolara P. Protection against ultraviolet B induced oxidative DNA damage in rabbit corneal derived cells (SIRC) by 4-coumaric acid. Toxicology 184 (2003) 141-147
38. Srinivasan M., Ram Sudheer A., Raveendran Pillai K., Raghu Kumar P., Sudhakaran P.R., and Menon V.P. Modulatory effects of curcumin on γ-radiation-induced cellular damage in primary culture of isolated rat hepatocytes. Environ. Toxicol. Pharm. 27 (2007) 98-105
39. Sreejayan, and Rao M.N. Curcuminoids as potent inhibitors of lipid peroxidation. J. Pharm. Pharmacol. 46 (1994) 1013-1016
40. Kalpana C., Sudheer A.R., Rajasekharan K.N., and Menon V.P. Comparative effects of curcumin and its synthetic analogue on tissue lipid peroxidation and antioxidant status during nicotine-induced toxicity. Singapore Med. J. 48 (2007) 124-130