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Volumn , Issue , 2011, Pages 197-215

Nongenomic Route of Action of TCDD: Identity, Characteristics, and Toxicological Significance

Author keywords

"nongenomic signaling" cancer promoter; Ligand activated AHR, "stress response"; TCDD nongenomic, toxicology

Indexed keywords


EID: 84862245261     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118140574.ch13     Document Type: Chapter
Times cited : (8)

References (91)
  • 1
    • 34548363297 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor sans xenobiotics: endogenous function in genetic model systems
    • McMillan, B. J. and Bradfield, C. A. (2007). The aryl hydrocarbon receptor sans xenobiotics: endogenous function in genetic model systems. Molecular Pharmacology, 72, 487-498.
    • (2007) Molecular Pharmacology , vol.72 , pp. 487-498
    • McMillan, B.J.1    Bradfield, C.A.2
  • 2
    • 0034676509 scopus 로고    scopus 로고
    • Is CYP1A1 induction always related to AHR signaling pathway?
    • Delescluse, C., Lemaire, G., de Sousa, G., and Rahmani, R. (2000). Is CYP1A1 induction always related to AHR signaling pathway? Toxicology, 153, 73-82.
    • (2000) Toxicology , vol.153 , pp. 73-82
    • Delescluse, C.1    Lemaire, G.2    de Sousa, G.3    Rahmani, R.4
  • 3
    • 47949133729 scopus 로고    scopus 로고
    • Inflammation
    • Weiss, U. (2008). Inflammation. Nature, 454, 427.
    • (2008) Nature , vol.454 , pp. 427
    • Weiss, U.1
  • 4
    • 26944440532 scopus 로고    scopus 로고
    • Post-transcriptional and nongenomic effects of glucocorticoids
    • Stellato, C. (2004). Post-transcriptional and nongenomic effects of glucocorticoids. Proceedings of American Thoracic Society, 1, 255-263.
    • (2004) Proceedings of American Thoracic Society , vol.1 , pp. 255-263
    • Stellato, C.1
  • 5
    • 34548289084 scopus 로고    scopus 로고
    • MAPK kinases as nucleo-cytoplasmic shuttles for PPARg
    • Burgermeister, E. and Seger, R. (2007). MAPK kinases as nucleo-cytoplasmic shuttles for PPARg. Cell Cycle, 6, 1539-1548.
    • (2007) Cell Cycle , vol.6 , pp. 1539-1548
    • Burgermeister, E.1    Seger, R.2
  • 6
    • 48149099758 scopus 로고    scopus 로고
    • Estrogen, NF-kB, and the heat shock response
    • Stice, J. P. and Knowlton, A. A. (2008). Estrogen, NF-kB, and the heat shock response. Molecular Medicine, 14, 517-527.
    • (2008) Molecular Medicine , vol.14 , pp. 517-527
    • Stice, J.P.1    Knowlton, A.A.2
  • 7
    • 0023777632 scopus 로고
    • 1α,25 (OH)2 vitamin D3: a steroid hormone capable of producing pleiotropic receptor-mediated biological responses by both genomic and nongenomic mechanisms
    • Cancela, L., Nemere, I., and Norman, A. W. (1988). 1α,25 (OH)2 vitamin D3: a steroid hormone capable of producing pleiotropic receptor-mediated biological responses by both genomic and nongenomic mechanisms. Journal of Steroid Biochemistry, 30, 33-9.
    • (1988) Journal of Steroid Biochemistry , vol.30 , pp. 33-9
    • Cancela, L.1    Nemere, I.2    Norman, A.W.3
  • 8
    • 33846862008 scopus 로고    scopus 로고
    • Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles
    • Vasudevan, N. and Pfaff, D. W. (2007). Membrane-initiated actions of estrogens in neuroendocrinology: emerging principles. Endocrine Reviews, 28, 1-19.
    • (2007) Endocrine Reviews , vol.28 , pp. 1-19
    • Vasudevan, N.1    Pfaff, D.W.2
  • 9
    • 0842291441 scopus 로고    scopus 로고
    • Making sense of cross-talk between steroid hormone receptors and intracellular signaling pathways: who will have the last word?
    • Lange, C. A. (2004). Making sense of cross-talk between steroid hormone receptors and intracellular signaling pathways: who will have the last word? Molecular Endocrinology, 18, 269-278.
    • (2004) Molecular Endocrinology , vol.18 , pp. 269-278
    • Lange, C.A.1
  • 10
    • 23044504053 scopus 로고    scopus 로고
    • Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer
    • Freeman, M. R., Cinar, B., and Lu, M. L. (2005). Membrane rafts as potential sites of nongenomic hormonal signaling in prostate cancer. Trends in Endocrinology and Metabolism, 16, 273-279.
    • (2005) Trends in Endocrinology and Metabolism , vol.16 , pp. 273-279
    • Freeman, M.R.1    Cinar, B.2    Lu, M.L.3
  • 11
    • 12244275029 scopus 로고    scopus 로고
    • Adynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins
    • Carlson, D. B. and Perdew, G. H. (2002).Adynamic role for the Ah receptor in cell signaling? Insights from a diverse group of Ah receptor interacting proteins. Journal of Biochemical and Molecular Toxicology, 16, 317-325.
    • (2002) Journal of Biochemical and Molecular Toxicology , vol.16 , pp. 317-325
    • Carlson, D.B.1    Perdew, G.H.2
  • 13
    • 0022407093 scopus 로고
    • Cell membrane associated protein kinase C as receptor of diterpene ester co-carcinogens of the tumor promoter type and the phenotypic expression of tumors
    • Hecker, E. (1985). Cell membrane associated protein kinase C as receptor of diterpene ester co-carcinogens of the tumor promoter type and the phenotypic expression of tumors. Arzneimittelforschung, 35, 1890-1903.
    • (1985) Arzneimittelforschung , vol.35 , pp. 1890-1903
    • Hecker, E.1
  • 15
    • 0025757038 scopus 로고
    • Arachidonic acid as a mediator of some of the actions of phorbolmyristate acetate, a tumor promoter and inducer of differentiation
    • Das, U. N. (1991). Arachidonic acid as a mediator of some of the actions of phorbolmyristate acetate, a tumor promoter and inducer of differentiation. Prostaglandins Leukotrienes and Essential Fatty Acids, 42, 241-244.
    • (1991) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.42 , pp. 241-244
    • Das, U.N.1
  • 16
    • 0033962448 scopus 로고    scopus 로고
    • Clinical relevance of the oxidative stress concept
    • Haffner, S.M. (2000). Clinical relevance of the oxidative stress concept. Metabolism, 49, 30-34.
    • (2000) Metabolism , vol.49 , pp. 30-34
    • Haffner, S.M.1
  • 17
    • 33750494955 scopus 로고    scopus 로고
    • Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kB and AP-1 as prime targets
    • Kundu, J. K., Shin, Y. K., and Surh, Y. J. (2006). Resveratrol modulates phorbol ester-induced pro-inflammatory signal transduction pathways in mouse skin in vivo: NF-kB and AP-1 as prime targets. Biochemical Pharmacology, 72, 1506-1515.
    • (2006) Biochemical Pharmacology , vol.72 , pp. 1506-1515
    • Kundu, J.K.1    Shin, Y.K.2    Surh, Y.J.3
  • 18
    • 46949111517 scopus 로고    scopus 로고
    • Curcumin decreases 12-O-tetradecanoylphorbol-13-acetateinduced protein kinaseCtranslocation to modulate downstream targets in mouse skin
    • Garg, R., Ramchandani, A. G., and Maru, G. B. (2008). Curcumin decreases 12-O-tetradecanoylphorbol-13-acetateinduced protein kinaseCtranslocation to modulate downstream targets in mouse skin. Carcinogenesis, 29, 1249-1257.
    • (2008) Carcinogenesis , vol.29 , pp. 1249-1257
    • Garg, R.1    Ramchandani, A.G.2    Maru, G.B.3
  • 19
    • 33746025348 scopus 로고    scopus 로고
    • Postgenomic approaches to understanding the mechanisms of environmentally induced phenotypic plasticity
    • Cossins, A., Fraser, J., Hughes, M., and Gracey,A. (2006). Postgenomic approaches to understanding the mechanisms of environmentally induced phenotypic plasticity. Journal of Experimental Biology, 209, 2328-2336.
    • (2006) Journal of Experimental Biology , vol.209 , pp. 2328-2336
    • Cossins, A.1    Fraser, J.2    Hughes, M.3    Gracey, A.4
  • 20
    • 36348964221 scopus 로고    scopus 로고
    • Heat shock proteins: linking danger and pathogen recognition
    • Osterloh, A. and Breloer, M. (2008). Heat shock proteins: linking danger and pathogen recognition. Medical Microbiology and Immunology, 197, 1-8.
    • (2008) Medical Microbiology and Immunology , vol.197 , pp. 1-8
    • Osterloh, A.1    Breloer, M.2
  • 21
    • 38849133044 scopus 로고    scopus 로고
    • A calculated response: control of inflammation by the innate immune system
    • Barton, G. M. (2008). A calculated response: control of inflammation by the innate immune system. Journal of Clinical Investigation, 118, 413-420.
    • (2008) Journal of Clinical Investigation , vol.118 , pp. 413-420
    • Barton, G.M.1
  • 22
    • 12844257378 scopus 로고    scopus 로고
    • Studies on the mechanism of rapid activation of protein tyrosine phosphorylation activities, particularly c-Src kinase, by TCDD in MCF10A
    • Mazina, O., Park, S., Sano, H., Wong, P., and Matsumura, F. (2004). Studies on the mechanism of rapid activation of protein tyrosine phosphorylation activities, particularly c-Src kinase, by TCDD in MCF10A. Journal of Biochemical and Molecular Toxicology, 18, 313-321.
    • (2004) Journal of Biochemical and Molecular Toxicology , vol.18 , pp. 313-321
    • Mazina, O.1    Park, S.2    Sano, H.3    Wong, P.4    Matsumura, F.5
  • 23
    • 12844265289 scopus 로고    scopus 로고
    • TCDD causes suppression of growth and differentiation of MCF10A, human mammary epithelial cells by interfering with their insulin receptor signaling through c-Src kinase and ERK activation
    • Park, S., Mazina, O., Kitagawa, A., Wong, P., and Matsumura, F. (2004). TCDD causes suppression of growth and differentiation of MCF10A, human mammary epithelial cells by interfering with their insulin receptor signaling through c-Src kinase and ERK activation. Journal of Biochemical and Molecular Toxicology, 18, 322-331.
    • (2004) Journal of Biochemical and Molecular Toxicology , vol.18 , pp. 322-331
    • Park, S.1    Mazina, O.2    Kitagawa, A.3    Wong, P.4    Matsumura, F.5
  • 24
    • 28844487903 scopus 로고    scopus 로고
    • Characterization of antiapoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A
    • Park, S. and Matsumura, F. (2006). Characterization of antiapoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A. Toxicology, 217, 139-146.
    • (2006) Toxicology , vol.217 , pp. 139-146
    • Park, S.1    Matsumura, F.2
  • 25
    • 45749119506 scopus 로고    scopus 로고
    • Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells
    • Dong, B. and Matsumura, F. (2008). Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells. Molecular Pharmacology, 74, 255-263.
    • (2008) Molecular Pharmacology , vol.74 , pp. 255-263
    • Dong, B.1    Matsumura, F.2
  • 26
    • 64749105469 scopus 로고    scopus 로고
    • The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells
    • Dong, B and Matsumura, F. (2009). The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells. Molecular Endocrinology, 23, 549-558.
    • (2009) Molecular Endocrinology , vol.23 , pp. 549-558
    • Dong, B.1    Matsumura, F.2
  • 27
    • 0026648792 scopus 로고
    • Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1
    • Puga, A., Nebert, D.W., and Carrier, F. (1992). Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1. DNA and Cell Biology, 11, 269-281.
    • (1992) DNA and Cell Biology , vol.11 , pp. 269-281
    • Puga, A.1    Nebert, D.W.2    Carrier, F.3
  • 29
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov, R. (2008). Origin and physiological roles of inflammation. Nature, 454, 428-435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 30
    • 55649091206 scopus 로고    scopus 로고
    • Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages
    • Sciullo, E. M., Vogel, C. F., Li, W., and Matsumura, F. (2008). Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages. Archives of Biochemistry and Biophysics, 480, 143-155.
    • (2008) Archives of Biochemistry and Biophysics , vol.480 , pp. 143-155
    • Sciullo, E.M.1    Vogel, C.F.2    Li, W.3    Matsumura, F.4
  • 31
    • 58849106775 scopus 로고    scopus 로고
    • Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes
    • Li, W. and Matsumura, F. (2008). Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. Biochemistry, 47, 13997-14008.
    • (2008) Biochemistry , vol.47 , pp. 13997-14008
    • Li, W.1    Matsumura, F.2
  • 32
    • 38649085672 scopus 로고    scopus 로고
    • Development of a human adipocyte model derived from human mesenchymal stem cells (hMSC) as a tool for toxicological studies on the action of TCDD
    • Li, W., Vogel, C. F., Fujiyoshi, P., and Matsumura, F. (2008). Development of a human adipocyte model derived from human mesenchymal stem cells (hMSC) as a tool for toxicological studies on the action of TCDD. Biological Chemistry, 389, 169-177.
    • (2008) Biological Chemistry , vol.389 , pp. 169-177
    • Li, W.1    Vogel, C.F.2    Fujiyoshi, P.3    Matsumura, F.4
  • 33
    • 70449658819 scopus 로고    scopus 로고
    • TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys
    • Dong, B., Nishimura, N., Vogel, C. F., Tohyama, C., and Matsumura, F. (2010). TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys. Biochemical Pharmacology, 79, 487-497.
    • (2010) Biochemical Pharmacology , vol.79 , pp. 487-497
    • Dong, B.1    Nishimura, N.2    Vogel, C.F.3    Tohyama, C.4    Matsumura, F.5
  • 34
    • 0021965629 scopus 로고
    • TCDD (2,3,7,8-tetrachlorodibenzo-pdioxin) causes increases in protein kinases particularly protein kinase C in the hepatic plasma membrane of the rat and the guinea pig
    • Bombick, D. W., Madhukar, B. V., Brewster, D. W., and Matsumura, F. (1985). TCDD (2,3,7,8-tetrachlorodibenzo-pdioxin) causes increases in protein kinases particularly protein kinase C in the hepatic plasma membrane of the rat and the guinea pig. Biochemical and Biophysical Research Communications, 127, 296-302.
    • (1985) Biochemical and Biophysical Research Communications , vol.127 , pp. 296-302
    • Bombick, D.W.1    Madhukar, B.V.2    Brewster, D.W.3    Matsumura, F.4
  • 35
    • 0023361772 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes elevation of the levels of the protein tyrosine kinase pp60c-src
    • Bombick, D.W. and Matsumura, F. (1987). 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes elevation of the levels of the protein tyrosine kinase pp60c-src. Journal of Biochemical Toxicology, 2, 141-154.
    • (1987) Journal of Biochemical Toxicology , vol.2 , pp. 141-154
    • Bombick, D.W.1    Matsumura, F.2
  • 36
    • 0024260540 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an increase in protein kinases associated with epidermal growth factor receptor in the hepatic plasma membrane
    • Madhukar, B. V., Ebner, K., Matsumura, F., Bombick, D. W., Brewster D. W., and Kawamoto, T. (1988). 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an increase in protein kinases associated with epidermal growth factor receptor in the hepatic plasma membrane. Journal of Biochemical Toxicology, 3, 261-277.
    • (1988) Journal of Biochemical Toxicology , vol.3 , pp. 261-277
    • Madhukar, B.V.1    Ebner, K.2    Matsumura, F.3    Bombick, D.W.4    Brewster, D.W.5    Kawamoto, T.6
  • 37
    • 0027433695 scopus 로고
    • TCDD-mediated changes in hepatic epidermal growth factor receptor may be a critical event in the hepatocarcinogenic action of TCDD
    • Sewall, C. H., Lucier, G.W., Tritscher, A. M., and Clark, G. C. (1993). TCDD-mediated changes in hepatic epidermal growth factor receptor may be a critical event in the hepatocarcinogenic action of TCDD. Carcinogenesis, 14, 1885-1893.
    • (1993) Carcinogenesis , vol.14 , pp. 1885-1893
    • Sewall, C.H.1    Lucier G.W Tritscher, A.M.2    Clark, G.C.3
  • 38
    • 0028311722 scopus 로고
    • A model of effects of TCDD on expression of rat liver proteins
    • Kohn, M. C. and Portier, C. J. (1994). A model of effects of TCDD on expression of rat liver proteins. Progress in Clinical Biology Research, 387, 211-222.
    • (1994) Progress in Clinical Biology Research , vol.387 , pp. 211-222
    • Kohn, M.C.1    Portier, C.J.2
  • 39
    • 0025600969 scopus 로고
    • TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD
    • Abbott, B. D. and Birnbaum, L. S. (1990). TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD. Toxicology and Applied Pharmacology, 106, 418-432.
    • (1990) Toxicology and Applied Pharmacology , vol.106 , pp. 418-432
    • Abbott, B.D.1    Birnbaum, L.S.2
  • 40
    • 20544456909 scopus 로고    scopus 로고
    • Effects of epidermal growth factor (EGF), transforming growth factor-alpha (TGFa), and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFa knockout mouse strains
    • Part A
    • Abbott, B. D., Buckalew, A. R., and Leffler, K. E. (2005). Effects of epidermal growth factor (EGF), transforming growth factor-alpha (TGFa), and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fusion of embryonic palates in serum-free organ culture using wild-type, EGF knockout, and TGFa knockout mouse strains. Birth Defects Research, Part A, 73, 447-454.
    • (2005) Birth Defects Research , vol.73 , pp. 447-454
    • Abbott, B.D.1    Buckalew, A.R.2    Leffler, K.E.3
  • 41
    • 0028093471 scopus 로고
    • How important is the protein phosphorylation pathway in the toxic expression of dioxin-type chemicals?
    • Matsumura, F. (1994). How important is the protein phosphorylation pathway in the toxic expression of dioxin-type chemicals? Biochemical Pharmacology, 48, 215-224.
    • (1994) Biochemical Pharmacology , vol.48 , pp. 215-224
    • Matsumura, F.1
  • 42
    • 33748649052 scopus 로고    scopus 로고
    • Mechanistic investigation on the cause for reduced toxicity of TCDD in wa-1 homozygous TGFa mutant strain of mice as compared its matching wild-type counterpart, C57BL/6J mice
    • Kitamura, N., Wong, P., and Matsumura, F. (2006). Mechanistic investigation on the cause for reduced toxicity of TCDD in wa-1 homozygous TGFa mutant strain of mice as compared its matching wild-type counterpart, C57BL/6J mice. Journal of Biochemical and Molecular Toxicology, 20, 151-158.
    • (2006) Journal of Biochemical and Molecular Toxicology , vol.20 , pp. 151-158
    • Kitamura, N.1    Wong, P.2    Matsumura, F.3
  • 43
    • 0033003606 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated membrane translocation of c-Src protein kinase in liver WB-F344 cells
    • Kohle, C., Gschaidmeier, H., Lauth, D., Topell, S., Zitzer, H., and Bock, K. W. (1999). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-mediated membrane translocation of c-Src protein kinase in liver WB-F344 cells. Archives of Toxicology, 73, 152-158.
    • (1999) Archives of Toxicology , vol.73 , pp. 152-158
    • Kohle, C.1    Gschaidmeier, H.2    Lauth, D.3    Topell, S.4    Zitzer, H.5    Bock, K.W.6
  • 44
    • 59149096524 scopus 로고    scopus 로고
    • Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AHR) signaling pathways
    • Haarmann-Stemmann, T., Bothe, H., and Abel, J. (2009). Growth factors, cytokines and their receptors as downstream targets of arylhydrocarbon receptor (AHR) signaling pathways. Biochemical Pharmacology, 77, 508-520.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 508-520
    • Haarmann-Stemmann, T.1    Bothe, H.2    Abel, J.3
  • 45
    • 0345677931 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes increases in expression of c-erb-A and levels of protein-tyrosine kinases in selected tissues of responsive mouse strains
    • Bombick, D. W., Jankun, J., Tullis, K., and Matsumura, F. (1988). 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes increases in expression of c-erb-A and levels of protein-tyrosine kinases in selected tissues of responsive mouse strains. Proceedings of the National Academy of Sciences of the United States of America, 85, 4128-4132.
    • (1988) Proceedings of the National Academy of Sciences of the United States of America , vol.85 , pp. 4128-4132
    • Bombick, D.W.1    Jankun, J.2    Tullis, K.3    Matsumura, F.4
  • 46
    • 0031567132 scopus 로고    scopus 로고
    • Comparative in vitro and in vivo protein kinase C activation by selected pesticides and transition metal salts
    • Bagchi, D., Bagchi, M., Tang, L., and Stohs, S. J. (1997). Comparative in vitro and in vivo protein kinase C activation by selected pesticides and transition metal salts. Toxicology Letters, 91, 31-37.
    • (1997) Toxicology Letters , vol.91 , pp. 31-37
    • Bagchi, D.1    Bagchi, M.2    Tang, L.3    Stohs, S.J.4
  • 47
    • 0029948241 scopus 로고    scopus 로고
    • Modulation of protein kinase C-related signal transduction by 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibits cell cycle dependence
    • Weber, T. J., Chapkin, R. S., Davidson, L. A., and Ramos, K. S. (1996). Modulation of protein kinase C-related signal transduction by 2,3,7,8-tetrachlorodibenzo-p-dioxin exhibits cell cycle dependence. Archives of Biochemistry and Biophysics, 328, 227-232.
    • (1996) Archives of Biochemistry and Biophysics , vol.328 , pp. 227-232
    • Weber, T.J.1    Chapkin, R.S.2    Davidson, L.A.3    Ramos, K.S.4
  • 48
    • 0347416983 scopus 로고    scopus 로고
    • Protein kinase C delta is activated in mouse ovarian surface epithelial cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Williams, S. R., Son, D. S., and Terranova, P. F. (2004). Protein kinase C delta is activated in mouse ovarian surface epithelial cancer cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Toxicology, 195, 1-17.
    • (2004) Toxicology , vol.195 , pp. 1-17
    • Williams, S.R.1    Son, D.S.2    Terranova, P.F.3
  • 49
    • 33847682316 scopus 로고    scopus 로고
    • TCDD alters PKC signaling pathways in developing neuronal cells in culture
    • Kim, S. Y., Lee, H. G., Choi, E. J., Park, K. Y., and Yang, J. H. (2007). TCDD alters PKC signaling pathways in developing neuronal cells in culture. Chemosphere, 67, S421-S427.
    • (2007) Chemosphere , vol.67
    • Kim, S.Y.1    Lee, H.G.2    Choi, E.J.3    Park, K.Y.4    Yang, J.H.5
  • 50
    • 0027333084 scopus 로고
    • Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on protein kinase C and inositol phosphate metabolism in primary cultures of rat hepatocytes
    • Wolfle, D., Schmutte, C., and Marquardt, H. (1993). Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on protein kinase C and inositol phosphate metabolism in primary cultures of rat hepatocytes. Carcinogenesis, 14, 2283-2287.
    • (1993) Carcinogenesis , vol.14 , pp. 2283-2287
    • Wolfle, D.1    Schmutte, C.2    Marquardt, H.3
  • 51
    • 0036449453 scopus 로고    scopus 로고
    • Review article: cyclic AMP sensors in living cells: what signals can they actually measure?
    • Rich, T. C. and Karpen, J. W. (2002). Review article: cyclic AMP sensors in living cells: what signals can they actually measure? Annals of Biomedical Engineering, 30, 1088-1099.
    • (2002) Annals of Biomedical Engineering , vol.30 , pp. 1088-1099
    • Rich, T.C.1    Karpen, J.W.2
  • 52
    • 59149105386 scopus 로고    scopus 로고
    • The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxinactivated Ah receptor to cause toxic effects
    • Matsumura, F. (2009). The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxinactivated Ah receptor to cause toxic effects. Biochemical Pharmacology, 77, 608-626.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 608-626
    • Matsumura, F.1
  • 54
    • 0028670595 scopus 로고
    • Omega-3 and omega-6 fatty acids and PGE2 stimulate the growth of normal but not tumor mouse mammary epithelial cells: evidence for alterations in the signaling pathways in tumor cells
    • McKenzie, K. E., Bandyopadhyay, G. K., Imagawa, W., Sun, K., and Nandi, S. (1994). Omega-3 and omega-6 fatty acids and PGE2 stimulate the growth of normal but not tumor mouse mammary epithelial cells: evidence for alterations in the signaling pathways in tumor cells. Prostaglandins Leukotrienes and Essential Fatty Acids, 51, 437-443.
    • (1994) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.51 , pp. 437-443
    • McKenzie, K.E.1    Bandyopadhyay, G.K.2    Imagawa, W.3    Sun, K.4    Nandi, S.5
  • 57
    • 70349336104 scopus 로고    scopus 로고
    • Protein kinase CK2 in health and disease: cellular functions of protein kinase CK2: a dynamic affair
    • Filhol, O. and Cochet, C. (2000). Protein kinase CK2 in health and disease: cellular functions of protein kinase CK2: a dynamic affair. Cell and Molecular Life Science, 66, 1830-1839.
    • (2000) Cell and Molecular Life Science , vol.66 , pp. 1830-1839
    • Filhol, O.1    Cochet, C.2
  • 58
    • 0028884540 scopus 로고
    • Regulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of the DNA binding activity of transcriptional factors via nuclear protein phosphorylation in guinea pig adipose tissue
    • Enan, E. and Matsumura, F. (1995). Regulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of the DNA binding activity of transcriptional factors via nuclear protein phosphorylation in guinea pig adipose tissue. Biochemical Pharmacology, 50, 1199-1206.
    • (1995) Biochemical Pharmacology , vol.50 , pp. 1199-1206
    • Enan, E.1    Matsumura, F.2
  • 59
    • 0033981668 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced changes in activities of nuclear protein kinases and phosphatases affecting DNA binding activity of c-Myc and AP-1 in the livers of guinea pigs
    • Ashida, H., Nagy, S., and Matsumura, F. (2000). 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced changes in activities of nuclear protein kinases and phosphatases affecting DNA binding activity of c-Myc and AP-1 in the livers of guinea pigs. Biochemical Pharmacology, 59, 741-751.
    • (2000) Biochemical Pharmacology , vol.59 , pp. 741-751
    • Ashida, H.1    Nagy, S.2    Matsumura, F.3
  • 60
    • 48149109091 scopus 로고    scopus 로고
    • Protein kinase CK2, and important regulator of the inflammatory response?
    • Singh, N. N. and Ramji, D. P. (2008). Protein kinase CK2, and important regulator of the inflammatory response? Journal of Molecular Medicine, 86, 887-897.
    • (2008) Journal of Molecular Medicine , vol.86 , pp. 887-897
    • Singh, N.N.1    Ramji, D.P.2
  • 61
    • 77952952508 scopus 로고    scopus 로고
    • Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes
    • Adenuga, D. and Rahman, I. (2010). Protein kinase CK2-mediated phosphorylation of HDAC2 regulates co-repressor formation, deacetylase activity and acetylation of HDAC2 by cigarette smoke and aldehydes. Archives of Biochemistry and Biophysics, 498, 62-73.
    • (2010) Archives of Biochemistry and Biophysics , vol.498 , pp. 62-73
    • Adenuga, D.1    Rahman, I.2
  • 63
    • 33645816542 scopus 로고    scopus 로고
    • TCDD suppresses insulinresponsive glucose transporter (GLUT-4) gene expression through C/EBP nuclear transcription factors in 3T3-L1 adipocytes
    • Liu, P. C. and Matsumura, F. (2007). TCDD suppresses insulinresponsive glucose transporter (GLUT-4) gene expression through C/EBP nuclear transcription factors in 3T3-L1 adipocytes. Journal of Biochemical and Molecular Toxicology, 20, 79-87.
    • (2007) Journal of Biochemical and Molecular Toxicology , vol.20 , pp. 79-87
    • Liu, P.C.1    Matsumura, F.2
  • 65
    • 59149093141 scopus 로고    scopus 로고
    • AHR acts as an E3 ubiquitin ligase to modulate steroid receptor functions
    • Ohtake, F., Fujii-Kuriyama, Y., and Kato, S. (2009). AHR acts as an E3 ubiquitin ligase to modulate steroid receptor functions. Biochemical Pharmacology, 77, 474-484.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 474-484
    • Ohtake, F.1    Fujii-Kuriyama, Y.2    Kato, S.3
  • 67
    • 59149104324 scopus 로고    scopus 로고
    • A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kB family
    • Vogel, C. F. and Matsumura, F. (2009). A new cross-talk between the aryl hydrocarbon receptor and RelB, a member of the NF-kB family. Biochemical Pharmacology, 77, 734-745.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 734-745
    • Vogel, C.F.1    Matsumura, F.2
  • 70
    • 0037139361 scopus 로고    scopus 로고
    • Effects of src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-src knockout mice procured through six generations of backcrossings to C57BL/6 mice
    • Dunlap, D. Y., Ikeda, I, Nagashima, H., Vogel, C. F., and Matsumura, F. (2002). Effects of src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-src knockout mice procured through six generations of backcrossings to C57BL/6 mice. Toxicology, 172, 125-141.
    • (2002) Toxicology , vol.172 , pp. 125-141
    • Dunlap, D.Y.1    Ikeda, I.2    Nagashima, H.3    Vogel, C.F.4    Matsumura, F.5
  • 71
    • 0141740717 scopus 로고    scopus 로고
    • Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with induced adipocyte differentiation in mouse embryonic fibroblasts (MEFs) involves tyrosine kinase c-Src
    • Vogel, C. F. and Matsumura, F. (2003). Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with induced adipocyte differentiation in mouse embryonic fibroblasts (MEFs) involves tyrosine kinase c-Src. Biochemical Pharmacology, 66, 1231-1244.
    • (2003) Biochemical Pharmacology , vol.66 , pp. 1231-1244
    • Vogel, C.F.1    Matsumura, F.2
  • 72
    • 0025606624 scopus 로고
    • A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism
    • Couture, L. A., Abbott, B. D., and Birnbaum L. S. (1990). A critical review of the developmental toxicity and teratogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin: recent advances toward understanding the mechanism. Teratology, 42, 619-627.
    • (1990) Teratology , vol.42 , pp. 619-627
    • Couture, L.A.1    Abbott, B.D.2    Birnbaum, L.S.3
  • 73
    • 0015698125 scopus 로고
    • Postnatal effects of maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Moore, J. A., Gupta, B. N., Zinkl, J. G., and Vos, J. G. (1973). Postnatal effects of maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Environmental Health Perspectives, 5, 81-85.
    • (1973) Environmental Health Perspectives , vol.5 , pp. 81-85
    • Moore, J.A.1    Gupta, B.N.2    Zinkl, J.G.3    Vos, J.G.4
  • 74
    • 0025969817 scopus 로고
    • Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery
    • Couture-Haws, L., Harris, M.W., McDonald, M. M., Lockhart, A. C., and Birnbaum, L. S. (1991). Hydronephrosis in mice exposed to TCDD-contaminated breast milk: identification of the peak period of sensitivity and assessment of potential recovery. Toxicology and Applied Pharmacology, 107, 413-428.
    • (1991) Toxicology and Applied Pharmacology , vol.107 , pp. 413-428
    • Couture-Haws, L.1    Harris, M.W.2    McDonald, M.M.3    Lockhart, A.C.4    Birnbaum, L.S.5
  • 76
    • 0029926250 scopus 로고    scopus 로고
    • Pharmacological manipulation of cyclo-oxygenase-2 in the inflamed hydronephrotic kidney
    • Seibert, K., Masferrer, J. L., Needleman, P., and Salvemini, D. (1996). Pharmacological manipulation of cyclo-oxygenase-2 in the inflamed hydronephrotic kidney. British Journal of Pharmacology, 117, 1016-1020.
    • (1996) British Journal of Pharmacology , vol.117 , pp. 1016-1020
    • Seibert, K.1    Masferrer, J.L.2    Needleman, P.3    Salvemini, D.4
  • 77
    • 4143150641 scopus 로고    scopus 로고
    • Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells
    • Yang, F. and Bleich, D. (2004). Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells. Journal of Biological Chemistry, 279, 35403-35411.
    • (2004) Journal of Biological Chemistry , vol.279 , pp. 35403-35411
    • Yang, F.1    Bleich, D.2
  • 78
    • 69049109776 scopus 로고    scopus 로고
    • Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A(2)alpha gene by 2,3,7,8-tetrachlorodibenzop-dioxin in mouse hepatoma Hepa-1c1c7 cells
    • Kinehara, M., Fukuda, I., Yoshida, K., and Ashida, H. (2009). Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A(2)alpha gene by 2,3,7,8-tetrachlorodibenzop-dioxin in mouse hepatoma Hepa-1c1c7 cells. Journal of Bioscience and Bioengineering, 108, 277-281.
    • (2009) Journal of Bioscience and Bioengineering , vol.108 , pp. 277-281
    • Kinehara, M.1    Fukuda, I.2    Yoshida, K.3    Ashida, H.4
  • 79
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: positive and negative feedback loops
    • Harris, S. L. and Levine, A. J. (2005). The p53 pathway: positive and negative feedback loops. Oncogene, 24, 2899-2908.
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 80
    • 25144494203 scopus 로고    scopus 로고
    • Redundancy of biological regulation as the basis of emergence of multidrug resistance
    • Shtil, A. A. and Azare, J. (2005). Redundancy of biological regulation as the basis of emergence of multidrug resistance. International Reviews on Cytology, 246, 1-29.
    • (2005) International Reviews on Cytology , vol.246 , pp. 1-29
    • Shtil, A.A.1    Azare, J.2
  • 81
    • 59349094114 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor (AHR) pathway as a regulatory pathway for cell adhesion and matrix metabolism
    • Kung, T., Murphy, K. A., and White, L. A. (2009). The aryl hydrocarbon receptor (AHR) pathway as a regulatory pathway for cell adhesion and matrix metabolism. Biochemical Pharmacology, 77, 536-546.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 536-546
    • Kung, T.1    Murphy, K.A.2    White, L.A.3
  • 82
    • 59149086440 scopus 로고    scopus 로고
    • AHR signaling in prostate growth, morphogenesis, and disease
    • Vezina, C. M., Lin, T. M., and Peterson, R. E. (2009). AHR signaling in prostate growth, morphogenesis, and disease. Biochemical Pharmacology, 77, 566-576.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 566-576
    • Vezina, C.M.1    Lin, T.M.2    Peterson, R.E.3
  • 83
    • 0030220845 scopus 로고    scopus 로고
    • Stimulation of calcium uptake in cultured rat hippocampal neurons by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Hanneman,W. H., Legare, M. E., Barhoumi, R., Burghardt, R. C., Safe, S., and Tiffany-Castiglioni, E. (1996). Stimulation of calcium uptake in cultured rat hippocampal neurons by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicology, 112, 19-28.
    • (1996) Toxicology , vol.112 , pp. 19-28
    • Hanneman, W.H.1    Legare, M.E.2    Barhoumi, R.3    Burghardt, R.C.4    Safe, S.5    Tiffany-Castiglioni, E.6
  • 84
    • 59149083365 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event?
    • Ray, S. and Swanson, H. I. (2009). Activation of the aryl hydrocarbon receptor by TCDD inhibits senescence: a tumor promoting event? Biochemical Pharmacology, 77, 681-688.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 681-688
    • Ray, S.1    Swanson, H.I.2
  • 86
    • 17344370677 scopus 로고    scopus 로고
    • Evolution and integration of innate immune recognition systems: the Toll-like receptors
    • Takeda, K. (2005). Evolution and integration of innate immune recognition systems: the Toll-like receptors. Journal of Endotoxin Research, 11, 51-55.
    • (2005) Journal of Endotoxin Research , vol.11 , pp. 51-55
    • Takeda, K.1
  • 87
    • 29244462498 scopus 로고    scopus 로고
    • Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway
    • Cullinan, S. B. and Diehl, J. A. (2006). Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway. International Journal of Biochemistry and Cell Biology, 38, 317-332.
    • (2006) International Journal of Biochemistry and Cell Biology , vol.38 , pp. 317-332
    • Cullinan, S.B.1    Diehl, J.A.2
  • 88
    • 0035965951 scopus 로고    scopus 로고
    • Concurrent inflammation as a determinant of susceptibility to toxicity from xenobiotic agents
    • Ganey, P. E. and Roth, R. A. (2001). Concurrent inflammation as a determinant of susceptibility to toxicity from xenobiotic agents. Toxicology, 169, 195-208.
    • (2001) Toxicology , vol.169 , pp. 195-208
    • Ganey, P.E.1    Roth, R.A.2
  • 89
    • 2942530310 scopus 로고    scopus 로고
    • ERKand p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions
    • Roux, P. P. and Blenis, J. (2004).ERKand p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions. Microbiology and Molecular Biology Reviews, 68, 320-344.
    • (2004) Microbiology and Molecular Biology Reviews , vol.68 , pp. 320-344
    • Roux, P.P.1    Blenis, J.2
  • 90
    • 59149086780 scopus 로고    scopus 로고
    • The immune phenotype of AHR null mouse mutants: not a simple mirror of xenobiotic receptor overactivation
    • Esser, C. (2009). The immune phenotype of AHR null mouse mutants: not a simple mirror of xenobiotic receptor overactivation. Biochemical Pharmacology, 77, 597-607.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 597-607
    • Esser, C.1
  • 91
    • 59149104736 scopus 로고    scopus 로고
    • AHR-mediated immunomodulation: the role of altered transcription
    • Kirkvliet N. I. (2009). AHR-mediated immunomodulation: the role of altered transcription. Biochemical Pharmacology, 77, 746-760.
    • (2009) Biochemical Pharmacology , vol.77 , pp. 746-760
    • Kirkvliet, N.I.1


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