메뉴 건너뛰기




Volumn 66, Issue 7, 2003, Pages 1231-1244

Interaction of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with induced adipocyte differentiation in mouse embryonic fibroblasts (MEFs) involves tyrosine kinase c-Src

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin (TCDD); Aryl hydrocarbon receptor (AhR); c Src; CCAAT enhancer binding protein (C EBP); Differentiation; Mouse embryonic fibroblasts (MEFs)

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACYL COENZYME A DESATURASE; AROMATIC HYDROCARBON RECEPTOR; ASCORBIC ACID; CCAAT ENHANCER BINDING PROTEIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; GLYCEROL 2 PHOSPHATE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; TRIACYLGLYCEROL; TYROSINE KINASE C SRC; UNCLASSIFIED DRUG;

EID: 0141740717     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(03)00404-0     Document Type: Article
Times cited : (46)

References (41)
  • 1
    • 0020010617 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons. Examinations of the mechanism of toxicity
    • Poland A., Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons. Examinations of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22:1982;517-554.
    • (1982) Annu. Rev. Pharmacol. Toxicol. , vol.22 , pp. 517-554
    • Poland, A.1    Knutson, J.C.2
  • 2
    • 0028891272 scopus 로고
    • Ah receptor role in TCDD toxicity: Still some mysteries but no myth - A reply to the commentary by Dr. L.W.D. Weber, Dr. B.U. Stahl
    • Okey A.B., Riddick D.S., Harper P.D. Ah receptor role in TCDD toxicity: still some mysteries but no myth - a reply to the commentary by Dr. L.W.D. Weber, Dr. B.U. Stahl. Toxicol. Lett. 75:1995;249-254.
    • (1995) Toxicol. Lett. , vol.75 , pp. 249-254
    • Okey, A.B.1    Riddick, D.S.2    Harper, P.D.3
  • 3
    • 0033990325 scopus 로고    scopus 로고
    • Role of the aromatic hydrocarbon receptor and (Ah) gene battery in the oxidative stress response, cell cycle control, and apoptosis
    • Nebert D.W., Roe A.L., Dieter M.Z., Solis W.A., Yang Y., Dalton T.P. Role of the aromatic hydrocarbon receptor and (Ah) gene battery in the oxidative stress response, cell cycle control, and apoptosis. Biochem. Pharmacol. 59:2000;65-85.
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 65-85
    • Nebert, D.W.1    Roe, A.L.2    Dieter, M.Z.3    Solis, W.A.4    Yang, Y.5    Dalton, T.P.6
  • 4
    • 0034009222 scopus 로고    scopus 로고
    • ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor
    • LaPres J.J., Glover E., Dunham E.E., Bunger M.K., Bradfield C.A. ARA9 modifies agonist signaling through an increase in cytosolic aryl hydrocarbon receptor. J. Biol. Chem. 275:2000;6153-6159.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6153-6159
    • LaPres, J.J.1    Glover, E.2    Dunham, E.E.3    Bunger, M.K.4    Bradfield, C.A.5
  • 5
    • 0033551511 scopus 로고    scopus 로고
    • Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization
    • Meyer B.K., Perdew G.H. Characterization of the AhR-hsp90-XAP2 core complex and the role of the immunophilin-related protein XAP2 in AhR stabilization. Biochemistry. 38:1999;8907-8917.
    • (1999) Biochemistry , vol.38 , pp. 8907-8917
    • Meyer, B.K.1    Perdew, G.H.2
  • 6
    • 0033531928 scopus 로고    scopus 로고
    • Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (aryl hydrocarbon) receptor
    • Kazlauskas A., Poellinger L., Pongratz I. Evidence that the co-chaperone p23 regulates ligand responsiveness of the dioxin (aryl hydrocarbon) receptor. J. Biol. Chem. 274:1999;13519-13524.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13519-13524
    • Kazlauskas, A.1    Poellinger, L.2    Pongratz, I.3
  • 7
    • 0030897705 scopus 로고    scopus 로고
    • Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo
    • Carver L.A., Bradfield C.A. Ligand-dependent interaction of the aryl hydrocarbon receptor with a novel immunophilin homolog in vivo. J. Biol. Chem. 72:1997;11452-11456.
    • (1997) J. Biol. Chem. , vol.72 , pp. 11452-11456
    • Carver, L.A.1    Bradfield, C.A.2
  • 8
    • 0031002895 scopus 로고    scopus 로고
    • A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Ma Q., Whitlock J.P.J. A novel cytoplasmic protein that interacts with the Ah receptor, contains tetratricopeptide repeat motifs, and augments the transcriptional response to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Biol. Chem. 272:1997;8878-8884.
    • (1997) J. Biol. Chem. , vol.272 , pp. 8878-8884
    • Ma, Q.1    Whitlock, J.P.J.2
  • 9
    • 0029963257 scopus 로고    scopus 로고
    • The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cycle and differentiated state independently of dioxin
    • Ma Q., Whitlock J.P.J. The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cycle and differentiated state independently of dioxin. Mol. Cell Biol. 16:1996;2144-2150.
    • (1996) Mol. Cell Biol. , vol.16 , pp. 2144-2150
    • Ma, Q.1    Whitlock, J.P.J.2
  • 12
    • 0025600969 scopus 로고
    • TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD
    • Abbott B.D., Birnbaum L.S. TCDD-induced altered expression of growth factors may have a role in producing cleft palate and enhancing the incidence of clefts after coadministration of retinoic acid and TCDD. Toxicol. Appl. Pharmacol. 106:1990;418-432.
    • (1990) Toxicol. Appl. Pharmacol. , vol.106 , pp. 418-432
    • Abbott, B.D.1    Birnbaum, L.S.2
  • 13
    • 0027600765 scopus 로고
    • Tetrachlorodibenzo-p-dioxin (TCDD) accelerates differentiation of murine preimplantation embryos in vitro
    • Blankenship A.L., Suffia M.C., Matsumura F., Walsh K.J., Wiley L.M. Tetrachlorodibenzo-p-dioxin (TCDD) accelerates differentiation of murine preimplantation embryos in vitro. Reprod. Toxicol. 7:1993;255-261.
    • (1993) Reprod. Toxicol. , vol.7 , pp. 255-261
    • Blankenship, A.L.1    Suffia, M.C.2    Matsumura, F.3    Walsh, K.J.4    Wiley, L.M.5
  • 14
    • 0028815062 scopus 로고
    • Inhibition of 3T3-L1 adipose differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Phillips M.A., Enan E., Liu P.C.C., Matsumura F. Inhibition of 3T3-L1 adipose differentiation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. J. Cell Sci. 108:1995;395-402.
    • (1995) J. Cell Sci. , vol.108 , pp. 395-402
    • Phillips, M.A.1    Enan, E.2    Liu, P.C.C.3    Matsumura, F.4
  • 15
    • 0028023138 scopus 로고
    • Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Gaido K.W., Maness S.C. Regulation of gene expression and acceleration of differentiation in human keratinocytes by 2,3,7,8-tetrachlorodibenzo-p-dioxin. Toxicol. Appl. Pharmacol. 127:1994;199-208.
    • (1994) Toxicol. Appl. Pharmacol. , vol.127 , pp. 199-208
    • Gaido, K.W.1    Maness, S.C.2
  • 16
    • 0023936663 scopus 로고
    • Reduction of adipose tissue lipoprotein lipase activity as a result of in vivo administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the guinea pig
    • Brewster D.W., Matsumura F. Reduction of adipose tissue lipoprotein lipase activity as a result of in vivo administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin to the guinea pig. Biochem. Pharmacol. 37:1988;2247-2253.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 2247-2253
    • Brewster, D.W.1    Matsumura, F.2
  • 17
    • 77957186809 scopus 로고
    • Relationship of alterations in energy metabolism to hypophagia in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • Potter C.L., Menahan L.A., Peterson R.E. Relationship of alterations in energy metabolism to hypophagia in rats treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam. Appl. Toxicol. 6:1986;89-97.
    • (1986) Fundam. Appl. Toxicol. , vol.6 , pp. 89-97
    • Potter, C.L.1    Menahan, L.A.2    Peterson, R.E.3
  • 18
    • 0031745543 scopus 로고    scopus 로고
    • Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis
    • Alexander D.L., Ganem L.G., Fernandez-Salguero P., Gonzalez F., Jefcoate C.R. Aryl-hydrocarbon receptor is an inhibitory regulator of lipid synthesis and of commitment to adipogenesis. J. Cell Sci. 111:1998;3311-3322.
    • (1998) J. Cell Sci. , vol.111 , pp. 3311-3322
    • Alexander, D.L.1    Ganem, L.G.2    Fernandez-Salguero, P.3    Gonzalez, F.4    Jefcoate, C.R.5
  • 19
    • 0029939543 scopus 로고    scopus 로고
    • Alteration by 2,3,7,8-tetrachlorodibenzo-p-dioxin of CCAAT/enhancer binding protein correlates with suppression of adipocyte differentiation in 3T3-L1 cells
    • Liu P.C.C., Phillips M.A., Matsumura F. Alteration by 2,3,7,8-tetrachlorodibenzo-p-dioxin of CCAAT/enhancer binding protein correlates with suppression of adipocyte differentiation in 3T3-L1 cells. Mol. Pharmacol. 49:1996;989-997.
    • (1996) Mol. Pharmacol. , vol.49 , pp. 989-997
    • Liu, P.C.C.1    Phillips, M.A.2    Matsumura, F.3
  • 20
    • 0030032069 scopus 로고    scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibition of fat cell differentiation
    • Brodie A.E., Azarenko V.A., Hu C.Y. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) inhibition of fat cell differentiation. Toxicol. Lett. 84:1996;55-59.
    • (1996) Toxicol. Lett. , vol.84 , pp. 55-59
    • Brodie, A.E.1    Azarenko, V.A.2    Hu, C.Y.3
  • 21
    • 0032504530 scopus 로고    scopus 로고
    • Depletion of arylhydrocarbon receptor during adipose differentiation in 3T3-L1 cells
    • Shimba S., Todoroki K., Aoyagi T., Tezuka M. Depletion of arylhydrocarbon receptor during adipose differentiation in 3T3-L1 cells. Biochem. Biophys. Res. Commun. 249:1998;131-137.
    • (1998) Biochem. Biophys. Res. Commun. , vol.249 , pp. 131-137
    • Shimba, S.1    Todoroki, K.2    Aoyagi, T.3    Tezuka, M.4
  • 22
    • 0028245235 scopus 로고
    • Regulation of glucose transport in the NIH 3T3-L1 preadipocyte cell line by TCDD
    • Olsen H., Enan E., Matsumura F. Regulation of glucose transport in the NIH 3T3-L1 preadipocyte cell line by TCDD. Environ. Health Perspect. 102:1994;454-459.
    • (1994) Environ. Health Perspect. , vol.102 , pp. 454-459
    • Olsen, H.1    Enan, E.2    Matsumura, F.3
  • 23
    • 0034858316 scopus 로고    scopus 로고
    • Arylhydrocarbon receptor (AhR) is involved in negative regulation of adipose differentiation in 3T3-L1 cells: AhR inhibits adipose differentiation independently of dioxin
    • Shimba S., Wada T., Tezuka M. Arylhydrocarbon receptor (AhR) is involved in negative regulation of adipose differentiation in 3T3-L1 cells: AhR inhibits adipose differentiation independently of dioxin. J. Cell Sci. 114:2001;2809-2817.
    • (2001) J. Cell Sci. , vol.114 , pp. 2809-2817
    • Shimba, S.1    Wada, T.2    Tezuka, M.3
  • 25
    • 0032515065 scopus 로고    scopus 로고
    • The role of C/EBP genes in adipocyte differentiation
    • Darlington G.J., Ross S.E., MacDougald O.A. The role of C/EBP genes in adipocyte differentiation. J. Biol. Chem. 273:1998;30057-30060.
    • (1998) J. Biol. Chem. , vol.273 , pp. 30057-30060
    • Darlington, G.J.1    Ross, S.E.2    MacDougald, O.A.3
  • 26
    • 0032784238 scopus 로고    scopus 로고
    • Differential toxicities of TCDD in vivo among normal, c-Src knockout, geldanamycin- and quercetin-treated mice
    • Dunlap D.Y., Moreno-Aliaga M.J., Wu Z., Matsumura F. Differential toxicities of TCDD in vivo among normal, c-Src knockout, geldanamycin- and quercetin-treated mice. Toxicology. 135:1999;95-107.
    • (1999) Toxicology , vol.135 , pp. 95-107
    • Dunlap, D.Y.1    Moreno-Aliaga, M.J.2    Wu, Z.3    Matsumura, F.4
  • 27
    • 0037139361 scopus 로고    scopus 로고
    • Effects of Src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-Src knockout mice procured through six generations of backcrossings to C57BL/6 mice
    • Dunlap D.Y., Ikeda I., Nagashima H., Vogel C.F.A., Matsumura F. Effects of Src-deficiency on the expression of in vivo toxicity of TCDD in a strain of c-Src knockout mice procured through six generations of backcrossings to C57BL/ 6 mice. Toxicology. 172:2002;125-141.
    • (2002) Toxicology , vol.172 , pp. 125-141
    • Dunlap, D.Y.1    Ikeda, I.2    Nagashima, H.3    Vogel, C.F.A.4    Matsumura, F.5
  • 28
    • 0016693548 scopus 로고
    • An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion
    • Green H., Kehinde O. An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell. 5:1975;19-27.
    • (1975) Cell , vol.5 , pp. 19-27
    • Green, H.1    Kehinde, O.2
  • 29
    • 0015752438 scopus 로고
    • Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division
    • Reznikoff C.A., Brankow D.W., Heidelberger C. Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division. Cancer Res. 33:1973;3231-3238.
    • (1973) Cancer Res. , vol.33 , pp. 3231-3238
    • Reznikoff, C.A.1    Brankow, D.W.2    Heidelberger, C.3
  • 30
    • 0026511284 scopus 로고
    • Antisense CCAAT/enhancer-binding protein in RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes
    • Lin F.T., Lane M.D. Antisense CCAAT/enhancer-binding protein in RNA suppresses coordinate gene expression and triglyceride accumulation during differentiation of 3T3-L1 preadipocytes. Genes Dev. 6:1992;533-544.
    • (1992) Genes Dev. , vol.6 , pp. 533-544
    • Lin, F.T.1    Lane, M.D.2
  • 31
    • 0020456517 scopus 로고
    • Hormonal regulation of stearoyl coenzyme A desaturase activity and lipogenesis during adipose conversion of 3T3-L1 cells
    • Kasturi R., Joshi V.C. Hormonal regulation of stearoyl coenzyme A desaturase activity and lipogenesis during adipose conversion of 3T3-L1 cells. J. Biol. Chem. 257:1982;12224-12230.
    • (1982) J. Biol. Chem. , vol.257 , pp. 12224-12230
    • Kasturi, R.1    Joshi, V.C.2
  • 33
    • 0028113007 scopus 로고
    • Transcriptional activation function of the mouse Ah receptor nuclear translocator
    • Li H., Dong L., Whitlock J.P. Transcriptional activation function of the mouse Ah receptor nuclear translocator. J. Biol. Chem. 269:1994;28098-28105.
    • (1994) J. Biol. Chem. , vol.269 , pp. 28098-28105
    • Li, H.1    Dong, L.2    Whitlock, J.P.3
  • 34
    • 0026050219 scopus 로고
    • Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
    • Cao Z., Umek R.M., McKnight S.L. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells. Genes Dev. 5:1991;1538-1552.
    • (1991) Genes Dev. , vol.5 , pp. 1538-1552
    • Cao, Z.1    Umek, R.M.2    McKnight, S.L.3
  • 35
    • 0024297268 scopus 로고
    • Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase
    • Ntambi J.M., Buhrow S.A., Kaestner K.H., Christy R.J., Sibley E., Kelly T.J. Jr., Lane M.D. Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase. J. Biol. Chem. 263(33):1988;17291-17300.
    • (1988) J. Biol. Chem. , vol.263 , Issue.33 , pp. 17291-17300
    • Ntambi, J.M.1    Buhrow, S.A.2    Kaestner, K.H.3    Christy, R.J.4    Sibley, E.5    Kelly T.J., Jr.6    Lane, M.D.7
  • 36
    • 0032891042 scopus 로고    scopus 로고
    • Troglitazone upregulates nitric oxide synthesis in vascular smooth muscle cells
    • Hattori Y., Hattori S., Kasai K. Troglitazone upregulates nitric oxide synthesis in vascular smooth muscle cells. Hypertension. 33:1999;943-948.
    • (1999) Hypertension , vol.33 , pp. 943-948
    • Hattori, Y.1    Hattori, S.2    Kasai, K.3
  • 37
    • 0025112855 scopus 로고
    • Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte
    • Sabath D.E., Broome H.E., Prystowsky M.B. Glyceraldehyde-3-phosphate dehydrogenase mRNA is a major interleukin 2-induced transcript in a cloned T-helper lymphocyte. Gene. 91:1990;185-191.
    • (1990) Gene , vol.91 , pp. 185-191
    • Sabath, D.E.1    Broome, H.E.2    Prystowsky, M.B.3
  • 38
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler S., Itoh S., Vivien D., ten Dijke P., Huet S., Gauthier J.M. Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:1998;3091-3100.
    • (1998) EMBO J. , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    Ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 39
    • 0024210678 scopus 로고
    • The DNA recognition site for the dioxin-Ah receptor complex: Nucleotide sequence and functional analysis
    • Denison M.S., Fisher J.M., Whitlock J.P. The DNA recognition site for the dioxin-Ah receptor complex: nucleotide sequence and functional analysis. J. Biol. Chem. 263:1988;17221-17224.
    • (1988) J. Biol. Chem. , vol.263 , pp. 17221-17224
    • Denison, M.S.1    Fisher, J.M.2    Whitlock, J.P.3
  • 40
    • 0036250319 scopus 로고    scopus 로고
    • Correlation between the high expression of C/EBPβ protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3-L1 cells
    • Liu P.C.C., Moreno-Aliaga M.J., Dunlap D.Y., Hu X.-M., Denison M.S., Matsumura F. Correlation between the high expression of C/EBPβ protein in F442A cells and their relative resistance to antiadipogenic action of TCDD in comparison to 3T3-L1 cells. J. Biochem. Mol. Toxicol. 16:2002;70-83.
    • (2002) J. Biochem. Mol. Toxicol. , vol.16 , pp. 70-83
    • Liu, P.C.C.1    Moreno-Aliaga, M.J.2    Dunlap, D.Y.3    Hu, X.-M.4    Denison, M.S.5    Matsumura, F.6
  • 41
    • 0032523221 scopus 로고    scopus 로고
    • Suppression of C/EBPα and induction of C/EPBβ in mouse adipose tissue and liver
    • Liu P.C.C., Dunlap D.Y., Matsumura F. Suppression of C/EBPα and induction of C/EPBβ in mouse adipose tissue and liver. Biochem. Pharmacol. 55:1998;1647-1655.
    • (1998) Biochem. Pharmacol. , vol.55 , pp. 1647-1655
    • Liu, P.C.C.1    Dunlap, D.Y.2    Matsumura, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.