2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced changes in activities of nuclear protein kinases and phosphatases affecting DNA binding activity of c-Myc and AP-1 in the livers of guinea pigs

Biochemical Pharmacology

Volumn 59, Issue 7, 2000, Pages 741-751

  Ashida, Hitoshi ^a   Nagy, Scott ^a   Matsumura, Fumio ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Casein kinase II; Guinea pig; Nuclear transcription factors; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CALCIUM CHLORIDE; CALMODULIN; CASEIN KINASE II; CYCLIC AMP; GENISTEIN; HEPARIN; MYC PROTEIN; OKADAIC ACID; PHOSPHATASE; PROTEIN KINASE; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR AP 1; VANADIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA BINDING; DNA RESPONSIVE ELEMENT; ENZYME ACTIVITY; GUINEA PIG; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TISSUE CULTURE; WESTERN BLOTTING;

ANIMALS; CELL NUCLEUS; DNA; GUINEA PIGS; MALE; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-MYC; TERATOGENS; TETRACHLORODIBENZODIOXIN; TRANSCRIPTION FACTOR AP-1;

EID: 0033981668     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00387-1     Document Type: Article

References (27)

1. Poland A., Knutson J.C. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons Examination of the mechanism of toxicity . Annu Rev Pharmacol Toxicol. 22:1982;517-554.
2. Silbergeld E.K., Gasiewicz T.A. Dioxins and the Ah receptor. Am J Ind Med. 16:1989;455-474.
3. Bock K.W. Aryl hydrocarbon or dioxin receptor Biologic and toxic responses . Rev Physiol Biochem Pharmacol. 125:1994;1-42.
4. Poland A., Kende A. The genetic expression of aryl hydrocarbon hydroxylase activity Evidence for a receptor mutation in nonresponsive mice . Hiatt H.H., Watson S.D., Winsten J.A. Origins of Human Cancer. 1977;847-867 Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
5. Poland A and Kimbrough RD (Eds.), Biological Mechanisms of Dioxin Action, Banbury Report 18, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1984.
6. Fisher J.M., Jones K.W., Whitlock J.P. Jr. Activation of transcription as a general mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin action. Mol Carcinog. 1:1989;216-221.
7. Madhukar B.V., Brewster D.W., Matsumura F. Effects of in vivo-administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on receptor binding of epidermal growth factor in the hepatic plasma membrane of rat, guinea pig, mouse, and hamster. Proc Natl Acad Sci USA. 81:1984;7407-7411.
8. c-src. J Biochem Toxicol. 2:1987;141-154.
9. ras and down-regulation of EGF receptor. Mol Toxicol. 2:1989;177-186.
10. Tullis K., Olsen H., Bombick D.W., Matsumura F., Jankun J. TCDD causes stimulation of c-ras expression in the hepatic plasma membrane in vivo and in vitro. J Biochem Toxicol. 7:1992;107-116.
11. Matsumura F. How important is the protein phosphorylation pathway in the toxic expression of dioxin-type chemicals? Biochem Pharmacol. 48:1994;215-224.
12. Ma X., Babish J.G. Acute 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure results in enhanced tyrosylphosphorylation and expression of murine hepatic cyclin dependent kinases. Biochem Biophys Res Commun. 197:1993;1070-1077.
13. cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210. J Cell Biol. 117:1992;1041-1053.
14. cdc2 in vitro and at mitosis. J Biol Chem. 267:1992;13943-13951.
15. Taylor S.J., Shalloway D. The cell cycle and c-Src. Curr Opin Genet Dev. 3:1993;26-34.
16. Hershman H.R. Primary response genes induced by growth factors and tumor promoters. Annu Rev Biochem. 60:1991;281-319.
17. Meek D.W., Street A.J. Nuclear protein phosphorylation and growth control. Biochem J. 287:1992;1-15.
18. Boyle W.J., Smeal T., Defize L.H., Angel P., Woodgett J.R., Karin M., Hunter T. Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA-binding activity. Cell. 64:1991;573-584.
19. Montminy M.R., Gonzalez G.A., Yamamoto K.K. Regulation of c-AMP-inducible genes by CREB. Trends Neurosci. 13:1990;184-188.
20. Pulverer B.J., Kyriakis J.M., Auruch J., Nikolakaki E., Woodgett J.R. Phosphorylation of c-Jun mediated by MAP kinases. Nature. 353:1991;670-674.
21. Lüscher B., Eisenman R.N. New light on Myc and Myb. Part I. Myc. Genes Dev. 4:1990;2025-2035.
22. Lin A., Frost J., Deng T., Smeal T., Al-Alawi N., Kikkawa U., Hunter T., Brenner D., Karin M. Casein kinase II is a negative regulator of c-Jun DNA binding and AP-1 activity. Cell. 70:1992;777-789.
23. Ashida H., Matsumura F. Effect of in vivo administered 2,3,7,8-tetrachlorodibenzo-p-dioxin on DNA binding activities of nuclear transcription factors in liver of guinea pigs. J Biochem Mol Toxicol. 12:1998;191-204.
24. Enan E., Matsumura F. Regulation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of the DNA binding activity of transcriptional factors via nuclear protein phosphorylation in guinea pig adipose tissue. Biochem Pharmacol. 50:1995;1199-1206.
25. Lowry O.H., Rosebrough N.J., Farr A.L., Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem. 193:1951;265-275.
26. Kuenzel E.A., Krebs E.G. A synthetic peptide substrate specific for casein kinase II. Proc Natl Acad Sci USA. 82:1985;737-741.
27. Sambrook J, Fritsch EF and Maniatis T, Labeling of synthetic oligonucleotides by phosphorylation with bacteriophage T4 polynucleotide kinase. Molecular Cloning: A Laboratory Manual, 2nd Edn, pp. 11.31-11.32. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, 1989.