The effects of daily consumption of grapefruit on body weight, lipids, and blood pressure in healthy, overweight adults

Metabolism: Clinical and Experimental

Volumn 61, Issue 7, 2012, Pages 1026-1035

  Dow, Caitlin A ^a   Going, Scott B ^a   Chow, Hsiao Hui S ^a,b   Patil, Bhimanagouda S ^c   Thomson, Cynthia A ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN;

ADULT; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; FEMALE; FOOD INTAKE; GRAPEFRUIT; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SYSTOLIC BLOOD PRESSURE; WAIST CIRCUMFERENCE; WEIGHT REDUCTION;

ADULT; BLOOD PRESSURE; CITRUS PARADISI; DIET, REDUCING; FEMALE; HUMANS; LIPIDS; MALE; MIDDLE AGED; OVERWEIGHT; WAIST CIRCUMFERENCE; WEIGHT LOSS;

EID: 84862133204     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2011.12.004     Document Type: Article

References (39)

1. H. Ghandehari, V. Le, and S. Kamal-Bahl Abdominal obesity and the spectrum of global cardiometabolic risks in US adults Int J Obes (Lond) 33 2009 239 248
2. Russell GV, Pierce CW, Nunley. L. Financial implications of obesity. Orthop Clin North Am 2011, 42:123-7, vii.
3. M. Selassie, and A.C. Sinha The epidemiology and aetiology of obesity: a global challenge Best Pract Res Clin Anaesthesiol 25 2011 1 9
4. G.L. Bakris Current perspectives on hypertension and metabolic syndrome J Manag Care Pharm 13 2007 S3 5
5. P.A. Heidenreich, J.G. Trogdon, and O.A. Khavjou Forecasting the future of cardiovascular disease in the United States: a policy statement from the American Heart Association Circulation 123 2011 933 944
6. Zelman K. The grapefruit diet: what it is. Healthy eating diet. Accessed at www.webmd.com/diet on May 27, 2011.
7. R.L. Duyff Food folklore: tales and truths about what we eat. 1st ed. pp 23 1999 John Wiley & Sons New York, NY
8. C. Dallas, A. Gerbi, and G. Tenca Lipolytic effect of a polyphenolic citrus dry extract of red orange, grapefruit, orange (SINETROL) in human body fat adipocytes. Mechanism of action by inhibition of cAMP-phosphodiesterase (PDE) Phytomedicine 15 2008 783 792
9. K.W. Cho, Y.O. Kim, and J.E. Andrade Dietary naringenin increases hepatic peroxisome proliferators-activated receptor alpha protein expression and decreases plasma triglyceride and adiposity in rats Eur J Nutr 50 2011 81 88
10. H.J. Silver, M.S. Dietrich, and K.D. Niswender Effects of grapefruit, grapefruit juice and water preloads on energy balance, weight loss, body composition, and cardiometabolic risk in free-living obese adults Nutr Metab (Lond) 8 2011 8
11. K. Fujioka, F. Greenway, and J. Sheard The effects of grapefruit on weight and insulin resistance: relationship to the metabolic syndrome J Med Food 9 2006 49 54 (Pubitemid 44153617)
12. J.E. Flood-Obbagy, and B.J. Rolls The effect of fruit in different forms on energy intake and satiety at a meal Appetite 52 2009 416 422
13. I. Erlund, M.L. Silaste, and G. Alfthan Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets, and diets high or low in fruit and vegetables Eur J Clin Nutr 56 2002 891 898
14. S. Rizza, R. Muniyappa, and M. Iantorno Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome J Clin Endocrinol Metab 96 2011 E782 792
15. C. Morand, C. Dubray, and D. Milenkovic Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers Am J Clin Nutr 93 2011 73 80
16. I. Demonty, Y. Lin, and Y.E. Zebregs The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women J Nutr 140 2010 1615 1620
17. F. Orallo, M. Camina, and E. Alvarez Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus-fruits flavonoid (+/-)-naringenin Planta Med 71 2005 99 107 (Pubitemid 40363550)
18. S.Y. Kim, H.J. Kim, and M.K. Lee Naringin time-dependently lowers hepatic cholesterol biosynthesis and plasma cholesterol in rats fed high-fat and high-cholesterol diet J Med Food 9 2006 582 586
19. E.E. Mulvihill, E.M. Allister, and B.G. Sutherland Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor-null mice with diet-induced insulin resistance Diabetes 58 2009 2198 2210
20. S.M. Jeon, H.K. Kim, and H.J. Kim Hypocholesterolemic and antioxidative effects of naringenin and its two metabolites in high-cholesterol fed rats Transl Res 149 2007 15 21 (Pubitemid 44969644)
21. R. Gupta, and S. Guptha Strategies for initial management of hypertension Indian J Med Res 132 2010 531 542
22. S. Gorinstein, A. Caspi, and I. Libman Red grapefruit positively influences serum triglyceride level in patients suffering from coronary atherosclerosis: studies in vitro and in humans J Agric Food Chem 54 2006 1887 1892
23. R. Landberg, Q. Sun, and E.B. Rimm Selected dietary flavonoids are associated with markers of inflammation and endothelial dysfunction in U.S. women J Nutr 141 2011 618 625
24. N.P.B. Raper, L. Ingwersen, L. Steinfeldt, and J. Anand An overview of USDA's Dietary Intake Data System J Food Compos Anal 17 2004 545 555 (Pubitemid 38801450)
25. T.G. Lohman, A.F. Roche, and R. Martorell Anthropometric standardization reference manual 1988 Human Kinetics Books Champaign (Ill)
26. R.A. Dale, L.H. Jensen, and M.J. Krantz Comparison of two point-of-care lipid analyzers for use in global cardiovascular risk assessments Ann Pharmacother 42 2008 633 639 (Pubitemid 351619933)
27. B.J.G. Girennavar, J.L. Jifon, and B.S. Patil Variation of bioactive furocoumarins and flavonoids in different varieties of grapefruit and pummelo Eur Food Res Technol 226 2008 1269 1275 (Pubitemid 351464489)
28. L.S. Freedman, A. Schatzkin, and D. Midthune Dealing with dietary measurement error in nutritional cohort studies J Natl Cancer Inst 103 2011 1086 1092
29. W. Shen, M. Punyanitya, and J. Chen Waist circumference correlates with metabolic syndrome indicators better than percentage fat Obesity (Silver Spring) 14 2006 727 736 (Pubitemid 46219749)
30. T.D. Giles, B.C. Berk, and H.R. Black Expanding the definition and classification of hypertension J Clin Hypertens (Greenwich) 7 2005 505 512
31. A.J. Wilburn, D.S. King, and J. Glisson The natural treatment of hypertension J Clin Hypertens (Greenwich) 6 2004 242 248
32. C. Antoniades, C. Shirodaria, and N. Warrick 5-Methyltetrahydrofolate rapidly improves endothelial function and decreases superoxide production in human vessels: effects on vascular tetrahydrobiopterin availability and endothelial nitric oxide synthase coupling Circulation 114 2006 1193 1201 (Pubitemid 44386484)
33. U.J. Jung, H.J. Kim, and J.S. Lee Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects Clin Nutr 22 2003 561 568 (Pubitemid 37455724)
34. J.W. Anderson, P. Baird, and R.H. Davis Jr Health benefits of dietary fiber Nutr Rev 67 2009 188 205
35. F. Lopez-Jimenez, and M. Cortes-Bergoderi Update: systemic diseases and the cardiovascular system (i): obesity and the heart Rev Esp Cardiol 64 2011 140 149
36. J.A. Lardizabal, and P.C. Deedwania Benefits of statin therapy and compliance in high risk cardiovascular patients Vasc Health Risk Manag 6 2010 843 853
37. R.Y. Mukhtar, and J.P. Reckless Statin-induced myositis: a commonly encountered or rare side effect? Curr Opin Lipidol 16 2005 640 647 (Pubitemid 43012162)
38. S. Fichtlscherer, C. Schmidt-Lucke, and S. Bojunga Differential effects of short-term lipid lowering with ezetimibe and statins on endothelial function in patients with CAD: clinical evidence for 'pleiotropic' functions of statin therapy Eur Heart J 27 2006 1182 1190
39. S.S. Dhaliwal, and T.A. Welborn Measurement error and ethnic comparisons of measures of abdominal obesity Prev Med 49 2009 148 152