Implication of cyclic nucleotide phosphodiesterase inhibition in the vasorelaxant activity of the citrus-fruits flavonoid (±)-naringenin

Planta Medica

Volumn 71, Issue 2, 2005, Pages 99-107

  Orallo, Francisco ^a   Camiña, Mercedes ^a   Álvarez, Ezequiel ^a   Basaran, Hélène ^b   Lugnier, Claire ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b CNRS   (France)

Author keywords

( ) naringenin; 45ca2+ uptake; Cyclic nucleotide phosphodiesterases; Flavanone; Rat aorta; Vasorelaxation

Indexed keywords

AURANTIIN; CALCIUM; CITRUS FRUIT EXTRACT; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; FLAVANONE; FLAVONOID; GLIBENCLAMIDE; HYPOXANTHINE; NARINGENIN; OKADAIC ACID; PHENYLEPHRINE; PHOSPHODIESTERASE I; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE V; POTASSIUM CHLORIDE; SCAVENGER; SUPEROXIDE; TETRYLAMMONIUM; XANTHINE OXIDASE;

ANIMAL CELL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; AORTA; AORTA MEDIA; ARTERY ENDOTHELIUM; ARTICLE; CALCIUM TRANSPORT; CITRUS FRUIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; NONHUMAN; RAT; SCAVENGING SYSTEM; SMOOTH MUSCLE FIBER; VASOCONSTRICTION; VASODILATATION;

ANIMALS; AORTA; CALCIUM; CITRUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; FLAVANONES; FLAVONOIDS; FRUIT; INHIBITORY CONCENTRATION 50; MALE; NUCLEOTIDES, CYCLIC; PHOSPHORIC DIESTER HYDROLASES; PHYTOTHERAPY; RATS; RATS, WISTAR; VASODILATION; VASODILATOR AGENTS;

ANIMALIA; BOVINAE; CITRUS;

EID: 14944367071     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-837774     Document Type: Article

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